Fig. 1

CDCA5 expression correlates with ccRCC progression in patients. A, B Data form TCGA dataset were analyzed to evaluate CDCA5 mRNA levels in normal kidney and tumor tissues (A), or different clinical stages (B). C Overall survival of patients stratified according to tumor CDCA5 expression. D Western blot analysis of CDCA5 protein expression in 10 ccRCC patients (T, tumor tissue; N, paired normal tissue). E Representative images of CDCA5 in different histological grades of ccRCC tumor tissues (n = 3 in each group). Scale bar: 100 um. ***P < 0.001