Toxoplasma gondii suppresses proliferation and migration of breast cancer cells by regulating their transcriptome

Table 5 Transcriptome changes of T. gondii after interaction with breast cancer cells annotation results of PHI database ^a

Transcriptome	After interaction with MCF-7 cells		After interaction with MDA-MB-231 cells
Transcriptome	T. gondii RH	T. gondii ME49	T. gondii RH	T. gondii ME49
Gene counts
Up-regulated	1369	843	1422	902
Down-regulated	1648	888	1569	1341
PHI database ^b annotation results genes which interacted with Human genes
Up-regulated	ROP16 ROP18	-	ROP16 ROP18	-
Down-regulated	crt	TgIST	crt	TgIST, GRA15, GRA24, MIC13

^a The filter criteria was set as fold changes ≥ 1.5 and adjusted p-value < 0.05;
^b PHI, Pathogen Host Interaction

ISSN: 1475-2867