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  1. To explore the effects of combinations of antiangiogenic agents and chemotherapy agents on non-small cell lung cancer (NSCLC) patients and indirectly compare the therapeutic effect of Endostar combined with ch...

    Authors: Yimin Li, Yonglin Yi, Anqi Lin, Peng Luo and Jian Zhang
    Citation: Cancer Cell International 2020 20:548
    Content type: Review Published on:

  2. RAS association domain family protein 1A (RASSF1A) promoter hypermethylation is suggested to be linked to hepatocellular carcinoma (HCC), but the results remained controversial.

    Authors: Gang Xu, Xiaoxiang Zhou, Jiali Xing, Yao Xiao, Bao Jin, Lejia Sun, Huayu Yang, Shunda Du, Haifeng Xu and Yilei Mao
    Citation: Cancer Cell International 2020 20:547
    Content type: Primary research Published on:

  3. Pathogenesis of colorectal cancer (CRC) is connected to deregulation of apoptosis while the effect of lncRNAs, as critical regulatory molecules, on this pathway is not clear well. The present study aimed to id...

    Authors: Fatemeh Akbari, Maryam Peymani, Ali Salehzadeh and Kamran Ghaedi
    Citation: Cancer Cell International 2020 20:546
    Content type: Primary research Published on:

  4. Docetaxel resistance affects prognosis in advanced prostate cancer (PCa). The precise mechanisms remain unclear. Transcription factor Forkhead box M1 (FOXM1), which participates in cell proliferation and cell ...

    Authors: Hongbo Yu, Zheng Xu, Maomao Guo, Weiwan Wang, Weican Zhang, Sudong Liang, Zhibin Xu, Jun Ye, Gangyi Zhu, Chenyang Zhang and Jianzhong Lin
    Citation: Cancer Cell International 2020 20:545
    Content type: Primary research Published on:

  5. The HER2 + tumor immune microenvironment is composed of macrophages, natural killer cells, and tumor infiltrating lymphocytes, which produce pro-inflammatory cytokines. Determining the effect of T-cells on HER...

    Authors: Patrick N. Song, Ameer Mansur, Kari J. Dugger, Tessa R. Davis, Grant Howard, Thomas E. Yankeelov and Anna G. Sorace
    Citation: Cancer Cell International 2020 20:544
    Content type: Primary research Published on:

  6. Long noncoding RNAs (lncRNAs) are important functional regulators of many biological processes of cancers. However, the mechanisms by which lncRNAs modulate androgen-independent prostate cancer (AIPC) developm...

    Authors: Weiyuan Li, Ganggang Yang, Dengke Yang, Dong Li and Qian Sun
    Citation: Cancer Cell International 2020 20:543
    Content type: Primary research Published on:

  7. ZBTB protein is an important member of the C2H2 zinc finger protein family. As a transcription factor, it is widely involved in the transcriptional regulation of genes, cell proliferation, differentiation, and...

    Authors: Rong Geng, Yuhua Zheng, Donghua zhou, Qingdong Li, Ruiman Li and Xiaoling Guo
    Citation: Cancer Cell International 2020 20:542
    Content type: Primary research Published on:

  8. Uterine corpus endometrial carcinoma (UCEC) is a frequent gynecological malignancy with a poor prognosis particularly at an advanced stage. Herein, this study aims to construct prognostic markers of UCEC based...

    Authors: Cankun Zhou, Chaomei Li, Fangli Yan and Yuhua Zheng
    Citation: Cancer Cell International 2020 20:541
    Content type: Primary research Published on:

  9. Yangyin Fuzheng Jiedu Prescription (YFJP) is a traditional Chinese medicine (TCM) indicated for the treatment of hepatocellular carcinoma (HCC). Its potential targets and molecular mechanisms are not clear. Th...

    Authors: Fengna Yan, Miaomiao Feng, Xinhui Wang, Peng Wang, Yuqing Xie, Xiaoli Liu, Weihong Li and Zhiyun Yang
    Citation: Cancer Cell International 2020 20:540
    Content type: Primary research Published on:

  10. Polyamines are aliphatic compounds with more than two amino groups that play various important roles in human cells. In cancer, polyamine metabolism dysfunction often occurs, and regulatory mechanisms of polya...

    Authors: Jiajing Li, Yan Meng, Xiaolin Wu and Yuxin Sun
    Citation: Cancer Cell International 2020 20:539
    Content type: Review Published on:

  11. Bladder cancer (BC) is a commonly diagnosed malignant tumor in the urinary system, with a high morbidity and a high recurrence rate. Current studies indicated that metabolism-associated genes (MAGs) having cri...

    Authors: Chengquan Shen, Jing Liu, Liping Wang, Zhijuan Liang, Haitao Niu and Yonghua Wang
    Citation: Cancer Cell International 2020 20:538
    Content type: Primary research Published on:

  12. Application of novel methods in cancer therapy is important in terms of management and treatment of the life-threatening disorder. It appears that autophagy is a potential target in cancer therapy, as a variet...

    Authors: Milad Ashrafizadeh, Zahra Ahmadi, Tahereh Farkhondeh and Saeed Samarghandian
    Citation: Cancer Cell International 2020 20:537
    Content type: Review Published on:

  13. Long noncoding RNAs (lncRNAs) are composed of > 200 nucleotides; they lack the ability to encode proteins but play important roles in a variety of human tumors. A large number of studies have shown that dysreg...

    Authors: Bin Xu, Jie Mei, Wei Ji, Zheng Bian, Jiantong Jiao, Jun Sun and Junfei Shao
    Citation: Cancer Cell International 2020 20:536
    Content type: Review Published on:

  14. Growing evidence has indicated the vital parts of long non-coding RNAs (lncRNAs) in modulating the progression of assorted human cancers, including cervical cancer (CC). Nevertheless, the role and mechanism of...

    Authors: Yihong Chen, Qiumei Wu, Jing Lin and Juanbing Wei
    Citation: Cancer Cell International 2020 20:535
    Content type: Primary research Published on:

  15. Drug resistance is a major obstacle to successful chemotherapy for epithelial ovarian cancer (EOC). We found a subset of miRNAs associated with the response to first-line platinum-based chemotherapy in EOC by ...

    Authors: Xiaotang Yu, Xinchen Zhang, Guang Wang, Bo Wang, Yanfang Ding, Jinyao Zhao, Hanlin Liu and Shiying Cui
    Citation: Cancer Cell International 2020 20:534
    Content type: Primary research Published on:

  17. Viruses are obligate parasites that depend on host cells to provide the energy and molecular precursors necessary for successful infection. The main component of virus-induced metabolic reprogramming is the ac...

    Authors: Jing Cai, Wenbo Zhu, Yuan Lin, Jun Hu, Xincheng Liu, Wencang Xu, Ying Liu, Cheng Hu, Songmin He, Shoufang Gong, Guangmei Yan and Jiankai Liang
    Citation: Cancer Cell International 2020 20:532
    Content type: Primary research Published on:

  18. Long noncoding RNAs (lncRNAs) have been proved to be an important regulator in gene expression. In almost all kinds of cancers, lncRNAs participated in the process of pathogenesis, invasion, and metastasis. Me...

    Authors: Shengyang Ge, Yuanyuan Mi, Xiaojun Zhao, Qingfeng Hu, Yijun Guo, Fan Zhong, Yang Zhang, Guowei Xia and Chuanyu Sun
    Citation: Cancer Cell International 2020 20:531
    Content type: Primary research Published on:

  19. The effect of the geriatric nutritional risk index (GNRI) on the prognosis of patients with gastrointestinal malignancy remains unclear. The aim of our study was to systematically explore the value of the GNRI...

    Authors: Hailun Xie, Shuangyi Tang, Lishuang Wei and Jialiang Gan
    Citation: Cancer Cell International 2020 20:530
    Content type: Review Published on:

  20. Abnormal proliferation, metastasis and epithelial-mesenchymal transformation (EMT) of lens epithelial cells (LECs) are direct factors of posterior capsular opacification (PCO). Nuclear enriched abundant transc...

    Authors: Huajun Wang and Guangying Zheng
    Citation: Cancer Cell International 2020 20:529
    Content type: Primary research Published on:

  21. Protein regulator of cytokinesis 1 (PRC1) has been reported to play important role in the pathogenesis of various cancers. However, its role in colon cancer has not been studied. Here, we aimed to investigate ...

    Authors: Tianxiang Xu, Xiaoxia Wang, Xiangdong Jia, Weishi Gao, Junhua Li, Fengying Gao, Ping Zhan and Wu Ji
    Citation: Cancer Cell International 2020 20:528
    Content type: Primary research Published on:

  22. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Mohsen Keshavarz, Ailar Sabbaghi, Seyed Mohammad Miri, Abolhasan Rezaeyan, Yaser Arjeini and Amir Ghaemi
    Citation: Cancer Cell International 2020 20:527
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2020 20:131

  23. Circular RNAs (circRNAs) have been discovered to participate in the carcinogenesis of multiple cancers. However, the role of circRNAs in esophageal squamous cell carcinoma (ESCC) progression is yet to be prope...

    Authors: Xiaoyong Li, Laichun Song, Bo Wang, Chao Tao, Lei Shi and Ming Xu
    Citation: Cancer Cell International 2020 20:526
    Content type: Primary research Published on:

  24. Melanoma as a type of skin cancer, is associated with a high mortality rate. Therefore, early diagnosis and efficient surgical treatment of this disease is very important. Photodynamic therapy (PDT) involves t...

    Authors: Khatereh Khorsandi, Reza Hosseinzadeh and Elham Chamani
    Citation: Cancer Cell International 2020 20:525
    Content type: Primary research Published on:

  26. Pyruvate kinase is a terminal enzyme in the glycolytic pathway, where it catalyzes the conversion of phosphoenolpyruvate to pyruvate and production of ATP via substrate level phosphorylation. PKM2 is one of fo...

    Authors: Xun Chen, Shangwu Chen and Dongsheng Yu
    Citation: Cancer Cell International 2020 20:523
    Content type: Review Published on:

  27. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Seyed Mohammad Miri, Mir Saeed Ebrahimzadeh, Elahe Abdolalipour, Mahsa Yazdi, Hassan Hosseini Ravandi and Amir Ghaemi
    Citation: Cancer Cell International 2020 20:522
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2020 20:380

  29. Novel chemotherapeutic drugs with good anti-tumor activity are of pressing need for bladder cancer treatment. In this study, plumbagin (PL), a natural plant-derived drug extracted from Chinese herbals, was ide...

    Authors: Renjie Zhang, Zijian Wang, Wenjie You, Fengfang Zhou, Zicheng Guo, Kaiyu Qian, Yu Xiao and Xinghuan Wang
    Citation: Cancer Cell International 2020 20:520
    Content type: Primary research Published on:

  30. Cytotoxic T-lymphocyte associated protein 4 (CTLA4) inhibitors have been shown to significantly prolong the overall survival (OS) in a wide range of cancers. However, its application in clear cell renal cell c...

    Authors: Shiyi Liu, Feiyan Wang, Wei Tan, Li Zhang, Fangfang Dai, Yanqing Wang, Yaqi Fan, Mengqin Yuan, Dongyong Yang, Yajing Zheng, Zhimin Deng, Yeqiang Liu and Yanxiang Cheng
    Citation: Cancer Cell International 2020 20:519
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2021 21:296

  31. Glioma is the most frequent and lethal primary brain malignancy. Amounting evidence has highlighted the importance of exosomal microRNAs (miRNAs or miRs) in this malignancy. This study aimed to investigate the...

    Authors: Meng Wang, Yi Zhao, Zhi-Yun Yu, Ren-De Zhang, Shu-Ang Li, Peng Zhang, Ti-Kun Shan, Xue-You Liu, Ze-Ming Wang, Pei-Chao Zhao and Hong-Wei Sun
    Citation: Cancer Cell International 2020 20:518
    Content type: Primary research Published on:

  32. Ovarian cancer (OC) is a common gynecological cancer and characterized by high metastatic potential. MicroRNAs (miRNAs, miRs) have the promise to be harnessed as prognostic and therapeutic biomarkers for OC. H...

    Authors: Yang Gu and Shulan Zhang
    Citation: Cancer Cell International 2020 20:517
    Content type: Primary research Published on:

  33. The upregulation of ADAM17 has been reported to be associated with invasion and metastasis in various tumors, however the molecular mechanism of ADAM17 in the progression of hepatocellular carcinoma (HCC) rema...

    Authors: Yuqi Xiang, Liyu Liu, Ying Wang, Bo Li, Jinwu Peng and Deyun Feng
    Citation: Cancer Cell International 2020 20:516
    Content type: Primary research Published on:

  34. CD137 is a target for tumor immunotherapy. However, the role of CD137 in gastric cancer (GC), especially in inducing GC cell apoptosis, has not been studied.

    Authors: Ben-Shun Hu, Tian Tang, Jun-Li Jia, Bi-Chen Xie, Tie-Long Wu, Ying-Yue Sheng, Yu-Zheng Xue and Hua-Min Tang
    Citation: Cancer Cell International 2020 20:513
    Content type: Primary research Published on:

  35. Prostate cancer (PCa) is a kind of malignancy occurring in the prostate gland. Substantial researches have proved the major role of long noncoding RNAs (lncRNAs) in PCa. However, the role of long intergenic no...

    Authors: Enhui Ma, Qianqian Wang, Jinhua Li, Xinqi Zhang, Zhenjia Guo and Xiaofeng Yang
    Citation: Cancer Cell International 2020 20:515
    Content type: Primary research Published on:

  36. Long noncoding RNAs (lncRNAs) are involved in the tumorigenesis and progression of human cancers, including renal cell carcinoma (RCC). Small nucleolar RNA host gene 4 (SNHG4) is reported to play an essential ...

    Authors: Jie Wu, Tingting Liu, Lulu Sun, Shaojin Zhang and Gang Dong
    Citation: Cancer Cell International 2020 20:514
    Content type: Primary research Published on:

  37. The prognosis of colon cancer is poor for metastasis, while the mechanism, especially adipocytes related, is not yet clear. The purpose of this study is to determine the effects of fatty acid binding protein 4...

    Authors: Wenying Tian, Wenjia Zhang, Yan Zhang, Tianyue Zhu, Yuting Hua, Hui Li, Qinglin Zhang and Min Xia
    Citation: Cancer Cell International 2020 20:512
    Content type: Primary research Published on:

  38. Colorectal cancer (CRC) is considered as the second common death-induced cancer. More recently, association of long non-coding RNAs (lncRNAs) with CRC has been extensively investigated. Therefore, the present ...

    Authors: Zhiyan Ruan, Hongling Deng, Minhua Liang, Zhe Xu, Manxiang Lai, Hong Ren, Xiangliang Deng and Xinguo Su
    Citation: Cancer Cell International 2020 20:511
    Content type: Primary research Published on:

  39. Due to the high morbidity and poor clinical outcomes, early predictive and prognostic biomarker identification is desiderated in colorectal cancer (CRC). As a homologue of the Deleted in Colorectal Cancer (DCC...

    Authors: Meng Zhang, Zhou Zhou, Xue-kai Pan, Yun-jiao Zhou, Hai-ou Li, Pei-shan Qiu, Meng-na Zhang, Ru-yi Peng, Hai-zhou Wang, Lan Liu, Jing Liu and Qiu Zhao
    Citation: Cancer Cell International 2020 20:510
    Content type: Primary research Published on:

  40. Plakophilins (PKPs) are widely involved in gene transcription, translation, and signal transduction, playing a crucial role in tumorigenesis and progression. However, the function and potential mechanism of PK...

    Authors: Lingling Gao, Xiao Li, Qian Guo, Xin Nie, Yingying Hao, Qing Liu, Juanjuan Liu, Liancheng Zhu, Limei Yan and Bei Lin
    Citation: Cancer Cell International 2020 20:509
    Content type: Primary research Published on:

  41. As an aggressive subtype of breast cancer with a high risk of recurrence, triple-negative breast cancer (TNBC) lacks available treatment targets. LncRNA MIR100HG promotes cell proliferation in TNBC. However, f...

    Authors: Fei-Yu Chen, Zhi-Yang Zhou, Ke-Jing Zhang, Jian Pang and Shou-Man Wang
    Citation: Cancer Cell International 2020 20:508
    Content type: Primary research Published on:

  43. Increasing evidence has indicated that long noncoding RNAs (lncRNAs) play various important roles in the development of cancers. The widespread applications of ribosome profiling and ribosome nascent chain com...

    Authors: Mujie Ye, Jingjing Zhang, Meng Wei, Baihui Liu and Kuiran Dong
    Citation: Cancer Cell International 2020 20:506
    Content type: Review Published on:

  44. Cancer stem cells (CSCs) play an important role in tumor invasion and metastasis. CD44 is the most commonly used marker of CSCs, with the potential to act as a determinant against the invasion and migration of...

    Authors: Xiaodong Yan, Dali Han, Zhiqiang Chen, Chao Han, Wei Dong, Li Han, Lei Zou, Jianbo Zhang, Yan Liu and Jie Chai
    Citation: Cancer Cell International 2020 20:505
    Content type: Primary research Published on:

  45. LOXL1-AS1 is a long non-coding RNA (lncRNA) that plays crucial roles in various cancers. However, the functional role of LOXL1-AS1 in laryngocarcinoma remains unclear. Thus we planned to probe into the functio...

    Authors: Guijun He, Wenfeng Yao, Liang Li, Yang Wu, Guojian Feng and Li Chen
    Citation: Cancer Cell International 2020 20:504
    Content type: Primary research Published on:

  46. Non-small cell lung cancer (NSCLC) includes lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC). MicroRNA (miRNA) plays an important role in the regulation of post-transcriptional gene expressio...

    Authors: Xinyue Du, Shuangmiao Wang, Xingyan Liu, Tao He, Xiangui Lin, Simin Wu, Dan Wang, Jiao Li, Wenhua Huang and Huiling Yang
    Citation: Cancer Cell International 2020 20:502
    Content type: Primary research Published on:

  47. Several studies have reported that the systemic immune-inflammation index (SII) is associated with the prognosis of patients with urologic cancers (UCs). The aim of this study was to systematically evaluate th...

    Authors: Yilong Huang, Yunfeng Gao, Yushen Wu and Huapeng Lin
    Citation: Cancer Cell International 2020 20:499
    Content type: Review Published on:

  48. Despite improvements in nasopharyngeal carcinoma (NPC) treatment, patients with recurrence and metastasis still have a poor prognosis. Thus, the identification of novel biomarkers is urgently needed to predict...

    Authors: Donglan Huang, Qianqian Liu, Weijun Zhang, Chunyue Huang, Ronghui Zheng, Guofeng Xie, Hongmei Wang, Baochang Jia, Jianjun Shi, Yawei Yuan and Min Deng
    Citation: Cancer Cell International 2020 20:498
    Content type: Primary research Published on:

  49. Long noncoding RNAs (LncRNAs) have been reported to critically regulate gastric cancer (GC). Recently, it was reported that LBX2 antisense RNA 1 (LBX2-AS1) is abnormally expressed in GC. However, the role of L...

    Authors: LiPan Peng, ZeZhong Chen, GuangChuan Wang, ShuBo Tian, Shuai Kong, Tao Xu, XiaoHua An and YueZhi Chen
    Citation: Cancer Cell International 2020 20:497
    Content type: Primary research Published on:

  50. Myeloid-derived suppressor cells (MDSCs) are known suppressors of antitumor immunity and contribute to immunosuppressive microenvironment during tumor development including lung cancer. Accumulating evidence s...

    Authors: Guangping Meng, Jinying Wei, Yanjun Wang, Danhua Qu and Jie Zhang
    Citation: Cancer Cell International 2020 20:495
    Content type: Primary research Published on:
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Cancer Cell International

ISSN: 1475-2867

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