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  1. Studies have shown that miR-502-5p functions as a tumor suppressor and is associated with tumor growth and metastasis. This study intends to uncover the potential mechanism of miR-502-5p functioning as a tumor...

    Authors: Wendao You, Xiaoyu Liu, Yang Yu, Chen Chen, Yujia Xiong, Yiting Liu, Yibin Sun, Chenhuan Tan, Hanshuo Zhang, Yadong Wang and Rui Li
    Citation: Cancer Cell International 2020 20:395
    Content type: Primary research Published on:

  3. Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNA...

    Authors: Xiaolong Zhu, Lan Jiang, Hui Yang, Tianbing Chen, Xingwei Wu and Kun Lv
    Citation: Cancer Cell International 2020 20:393
    Content type: Primary research Published on:

  4. The situation faced by breast cancer patients, especially those with triple-negative breast cancer, is still grave. More effective therapeutic targets are needed to optimize the clinical management of breast c...

    Authors: Wei Peng, Jian-Di Li, Jing-Jing Zeng, Xiao-Ping Zou, Deng Tang, Wei Tang, Min-Hua Rong, Ying Li, Wen-Bin Dai, Zhong-Qing Tang, Zhen-Bo Feng and Gang Chen
    Citation: Cancer Cell International 2020 20:392
    Content type: Primary research Published on:

  5. Circular RNAs (circRNAs) are a new group of non-coding RNAs that play vital roles in cancer occurrence, including gastric cancer (GC). Nevertheless, the role and underlying regulatory mechanisms of circHIPK3 i...

    Authors: Qingchun Li, Yuan Tian, Yun Liang and Chang Li
    Citation: Cancer Cell International 2020 20:391
    Content type: Primary research Published on:

  6. The introduction of combined conventional cytostatics and pathway-specific inhibitors has opened new treatment options for several cancer types including hematologic neoplasia such as leukaemias. As the detail...

    Authors: L.-M. Sklarz, Y. S. Gladbach, M. Ernst, M. Hamed, C. Roolf, S. Sender, J. Beck, E. Schütz, S. Fischer, S. Struckmann, C. Junghanss, G. Fuellen and H. Murua Escobar
    Citation: Cancer Cell International 2020 20:390
    Content type: Primary research Published on:

  7. Recently, extensive evidence has clarified the crucial role of circular RNAs (circRNAs) as a pro-tumor or anti-cancer participant in human malignancies. A new circRNA derived from oxysterol binding protein lik...

    Authors: Shanshan Yang, Yiwen Jiang, Xiaoli Ren, Dan Feng, Liaoyun Zhang, Deying He, Shiyao Hong, Li Jin, Fang Zhang and Shun Lu
    Citation: Cancer Cell International 2020 20:389
    Content type: Primary research Published on:

  8. Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors originated from digestive system around the world and the treatment was limited by the unclear mechanism. DNA polymerase e...

    Authors: Yongjun Zhu, Gang Chen, Yang Song, Zhiming Chen and Xiaofeng Chen
    Citation: Cancer Cell International 2020 20:388
    Content type: Primary research Published on:

  9. The incidence and death rate of non-small cell lung cancer (NSCLC) in China ranks the first among the malignant tumors. Circular RNA (circRNA) was reported to be involved in the progression of NSCLC. Our study...

    Authors: Liang Wang, Lantao Zhao and Yonghong Wang
    Citation: Cancer Cell International 2020 20:387
    Content type: Primary research Published on:

  10. The aim of this study was to identify prognostic long non-coding RNAs (lncRNAs) and develop a multi-lncRNA signature for suvival prediction in esophageal squamous cell carcinoma (ESCC).

    Authors: Lan zhang, Pan Li, Enjie Liu, Chenju Xing, Di Zhu, Jianying Zhang, Weiwei Wang and Guozhong Jiang
    Citation: Cancer Cell International 2020 20:386
    Content type: Primary research Published on:

  11. Cervical squamous cell carcinoma (CSCC) is one of the main causes of cancer-related deaths in women worldwide. The present study was conducted with the main objective of determining the potential role of recep...

    Authors: Jing Wang and Shengcai Chen
    Citation: Cancer Cell International 2020 20:385
    Content type: Primary research Published on:

  12. Melanoma is a cancer that has a high mortality rate in the absence of targeted therapy. Conventional therapies such as surgery, chemotherapy, and radiotherapy are associated with poor prognosis. The expression...

    Authors: Shaghayegh Haghjooy Javanmard, Golnaz Vaseghi, Ahmad Ghasemi, Laleh Rafiee, Gordon A. Ferns, Hajar Naji Esfahani and Reza Nedaeinia
    Citation: Cancer Cell International 2020 20:384
    Content type: Primary research Published on:

  13. The pathogenesis of multiple myeloma (MM) is not completely known. Uncovering the potential mechanism of MM initiation and progression is essential for identifying novel diagnostic and therapeutic targets. Her...

    Authors: Yan Wang, Quande Lin, Chunge Song, Ruojin Ma and Xiaojie Li
    Citation: Cancer Cell International 2020 20:383
    Content type: Primary research Published on:

  14. Pancreatic cancer is a common malignant tumor of the digestive tract. It has a high degree of malignancy and poor prognosis. Finding effective molecular markers has great significance for pancreatic cancer dia...

    Authors: Mu-jing Ke, Lian-dong Ji and Yi-xiong Li
    Citation: Cancer Cell International 2020 20:382
    Content type: Primary research Published on:

  15. Chemo-resistance is one of the main obstacles in the treatment of prostate cancer (PCa). Long non-coding RNA small nucleolar RNA host gene 6 (SNHG6) is involved in the chemo-resistance of various tumors. We ai...

    Authors: Chunhui Cao, Guanghai Sun and Chunlin Liu
    Citation: Cancer Cell International 2020 20:381
    Content type: Primary research Published on:

  16. Newcastle disease virus (NDV) has shown noticeable oncolytic properties, especially against cervical cancer. However, in order to improve the spread rate and oncotoxicity of the virus, employment of other ther...

    Authors: Seyed Mohammad Miri, Mir Saeed Ebrahimzadeh, Elahe Abdolalipour, Mahsa Yazdi, Hassan Hosseini Ravandi and Amir Ghaemi
    Citation: Cancer Cell International 2020 20:380
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:522

  17. The roots of Salvia miltiorrhiza are used in traditional Chinese medicine (TCM) and have high medicinal value. Tanshinone IIA (Tan IIA) is the active ingredient of Salvia miltiorrhiza which can inhibit the growth...

    Authors: Zi-Yuan Nie, Ming-Hui Zhao, Bao-Qian Cheng, Rong-Fang Pan, Tian-Rui Wang, Yan Qin and Xue-Jun Zhang
    Citation: Cancer Cell International 2020 20:379
    Content type: Primary research Published on:

  18. Growing evidence has demonstrated that glutathione peroxidases (GPXs) family genes play critical roles in onset and progression of human cancer. However, a systematic study regarding expression, diagnostic and...

    Authors: Weiyang Lou, Bisha Ding, Shuqian Wang and Peifen Fu
    Citation: Cancer Cell International 2020 20:378
    Content type: Primary research Published on:

  19. Breast cancer is a common malignancy in women. Among breast cancer types, triple-negative breast cancer (TNBC) tends to affect younger women, is prone to axillary lymph node, lung, and bone metastases; and has...

    Authors: Chengli Lu, Zhiyuan Ma, Xiaoming Cheng, Huichao Wu, Biguang Tuo, Xuemei Liu and Taolang Li
    Citation: Cancer Cell International 2020 20:377
    Content type: Review Published on:

  20. Numerous studies have shown that long noncoding RNAs play important roles in human cancer progression. Although zebrafish xenografts have recently become a novel in vivo model for human cancer research, whethe...

    Authors: Wenyi Shen, Juan Pu, Jing Sun, Bing Tan, Wei Wang, Lili Wang, Jianmeng Cheng and Yangsong Zuo
    Citation: Cancer Cell International 2020 20:376
    Content type: Primary research Published on:

  21. The aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the diagnosis and treatment of B cell malignancies. With 4.3% of all new can...

    Authors: Michelle H. Townsend, Zac E. Ence, Taylor P. Cox, John E. Lattin, Weston Burrup, Michael K. Boyer, Stephen R. Piccolo, Richard A. Robison and Kim L. O’Neill
    Citation: Cancer Cell International 2020 20:375
    Content type: Primary research Published on:

  22. Glioma is the most primary central nervous system tumor in adults. The 5 year survival rate for glioma patients remains poor, although treatment strategies had improved in the past few decades. The cumulative ...

    Authors: Niya Long, Liangzhao Chu, Jun Jia, Shuo Peng, Yuan Gao, Hua Yang, Yaoming Yang, Yan Zhao and Jian Liu
    Citation: Cancer Cell International 2020 20:374
    Content type: Primary research Published on:

  23. Ovarian cancer (OC) is the most malignant tumor in the female reproductive system. About 75% of OC in complete remission of clinical symptoms still develop a recurrence. Therefore, searching for new treatment ...

    Authors: Fangfang Bi, Ying Chen and Qing Yang
    Citation: Cancer Cell International 2020 20:373
    Content type: Primary research Published on:

  24. Long non-coding RNAs (LncRNAs) have been increasingly confirmed to be abnormally expressed in human cancer and closely related to tumorigenesis. LncRNA ACTA2-AS1 is abnormally expressed in multiple tumors and ...

    Authors: Lingli Luo, Min Wang, Xianping Li, Can Luo, Shan Tan, Sheng Yin, Lei Liu and Xiaolin Zhu
    Citation: Cancer Cell International 2020 20:372
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2024 24:76

  25. Hepatocellular carcinoma (HCC) is the most aggressive and frequently diagnosed malignancy of the liver. Despite aggressive therapy, life expectancy of many patients in these cases is extended by only a few mon...

    Authors: Yi Xiao, Qiang Gong, Wenhong Wang, Fang Liu, Qinghong Kong, Feng Pan, Xiaoke Zhang, Changyan Yu, Shanshan Hu, Fang Fan, Sanhua Li and Yun Liu
    Citation: Cancer Cell International 2020 20:371
    Content type: Primary research Published on:

  27. Reversible acetylation of α-tubulin has been implicated in modulating microtuble structures and functions, which may subsequently involve in cellular apoptosis and autophage. But how to trigger apoptosis or au...

    Authors: Qilin Wang and Xiangguo Liu
    Citation: Cancer Cell International 2020 20:369
    Content type: Primary research Published on:

  29. T cell receptor gamma locus antisense RNA 1 (TRG-AS1) has been reported to involve in the progression of glioblastoma, however the role and its underlying molecular mechanism in hepatocellular carcinoma (HCC) ...

    Authors: Xuehu Sun, Yeben Qian, Xingyu Wang, Rongge Cao, Jianlin Zhang, Weidong Chen and Maoyong Fang
    Citation: Cancer Cell International 2020 20:367
    Content type: Primary research Published on:

  30. Transgelin, an actin-binding protein, is associated with cytoskeleton remodeling. Findings from our previous studies demonstrated that transgelin was up-regulated in node-positive colorectal cancer (CRC) versu...

    Authors: Zhen-xian Lew, Hui-min Zhou, Yuan-yuan Fang, Zhen Ye, Wa Zhong, Xin-yi Yang, Zhong Yu, Dan-yu Chen, Si-min Luo, Li-fei Chen and Ying Lin
    Citation: Cancer Cell International 2020 20:366
    Content type: Primary research Published on:

  31. Mammary Paget’s disease (MPD) is an uncommon cutaneous intraepithelial malignancy with ulceration of the nipple or areola. Its pathogenesis and genomic mutation remain largely unknown and no cell lines are est...

    Authors: Bo Pan, Dongyi Zhao, Yaqian Liu, Na Li, Chen Song, Ning Li, Xuelu Li, Man Li and Zuowei Zhao
    Citation: Cancer Cell International 2020 20:365
    Content type: Primary research Published on:

  32. Cisplatin resistance of ovarian yolk sac tumors (oYST) is a clinical challenge due to dismal patient prognosis, even though the disease is extremely rare. We investigated potential association between cisplati...

    Authors: Silvia Schmidtova, Lambert C. J. Dorssers, Katarina Kalavska, Ad J. M. Gillis, J. Wolter Oosterhuis, Hans Stoop, Svetlana Miklikova, Zuzana Kozovska, Monika Burikova, Katarina Gercakova, Erika Durinikova, Michal Chovanec, Michal Mego, Lucia Kucerova and Leendert H. J. Looijenga
    Citation: Cancer Cell International 2020 20:364
    Content type: Primary research Published on:

  34. As a new kind of RNA, circular RNA (circRNA) is a endogenous non-coding RNA with circular structure, which has the characteristics of universality, stability, conservatism and specificity. CircRNA can specific...

    Authors: Xiaoqing Zhang, Ning Lu, Li Wang, Yixuan Wang, Minna Li, Ying Zhou, Honglin Yan, Manli Cui, Mingxin Zhang and Lingmin Zhang
    Citation: Cancer Cell International 2020 20:362
    Content type: Review Published on:

  35. Human papillomaviruses (HPVs) and Epstein–Barr virus (EBV), known oncoviruses, can be co-present and cooperate in the initiation and/or progression of human carcinomas, including head and neck. Based on this f...

    Authors: Hamda Al-Thawadi, Ishita Gupta, Ayesha Jabeen, Faruk Skenderi, Tahar Aboulkassim, Amber Yasmeen, Mohammed I. Malki, Gerald Batist, Semir Vranic and Ala-Eddin Al Moustafa
    Citation: Cancer Cell International 2020 20:361
    Content type: Primary research Published on:

  36. Hepatocellular carcinoma (HCC) is the most common malignant heterogeneous disease in primary liver tumors. Circular RNA hsa_circ_0000517 (hsa_circ_0000517) is connected with HCC prognosis. Nevertheless, there ...

    Authors: Shuwei He, Zhengwu Guo, Qian Kang, Xu Wang and Xingmin Han
    Citation: Cancer Cell International 2020 20:360
    Content type: Primary research Published on:

  38. Cervical cancer (CC) is the 4th most common cancer-related death in gynecological cancer worldwide. It has been reported that many lncRNAs contribute to oncogenesis although the fundamental mechanisms are basi...

    Authors: Xinghua Shi, Jinzhi Huo, Xingping Gao, Hua Cai and Weipei Zhu
    Citation: Cancer Cell International 2020 20:358
    Content type: Primary research Published on:

  39. Increasing researches have reported that circular RNA UBAP2 (circUBAP2) may be a potential prognosis biomarker and participate in the development of several cancers; however, the role of circUBAP2 in cervical ...

    Authors: Lingli Meng, Xiupeng Jia, Wenying Yu, Chunnian Wang, Jie Chen and Fenglei Liu
    Citation: Cancer Cell International 2020 20:357
    Content type: Primary research Published on:

  40. EPB41L1 gene (erythrocyte membrane protein band 4.1 like 1) encodes the protein 4.1N, a member of 4.1 family, playing a vital role in cell adhesion and migration, which is associated with the malignant progres...

    Authors: Taotao Liang, Siyao Sang, Qi Shao, Chen Chen, Zhichao Deng, Ting Wang and Qiaozhen Kang
    Citation: Cancer Cell International 2020 20:356
    Content type: Primary research Published on:

  41. Esophageal cancer is one of the most common cancers worldwide with poor prognosis and high mortality. The transcription factor SNAI1, encoding Snail1, is important for metastatic progression in esophageal cancer ...

    Authors: Gang Li, Hong-wei Qi, He-gui Dong, Ping Bai, Ming Sun and Hai-yan Liu
    Citation: Cancer Cell International 2020 20:355
    Content type: Primary research Published on:

  42. Cervical cancer (CC) is one of the most common female malignancies over the world. Microtubule-associated protein 7 (MAP7) belongs to the family of microtubule-associated proteins (MAPs) which involve in micro...

    Authors: Ning Tang, Dan Lyu, Jian-Fang Chang, Zhi-Tao Liu, Yan Zhang and Hai-Ping Liu
    Citation: Cancer Cell International 2020 20:354
    Content type: Primary research Published on:

  44. anaplastic thyroid cancer (ATC) is one of the most lethal and aggressive cancers. Evidence has shown that the tumorigenesis of ATC is a multistep process involving the accumulation of genetic and epigenetic ch...

    Authors: Hilda Samimi, Sayed Mahmoud Sajjadi-Jazi, Soroush Seifirad, Rasha Atlasi, Habibollah Mahmoodzadeh, Mohammad Ali Faghihi and Vahid Haghpanah
    Citation: Cancer Cell International 2020 20:352
    Content type: Review Published on:

  45. Gastric cancer is a serious malignant tumor associated with aberrant circular RNAs (circRNAs) expression. In this study, we aim to investigate the role and the underlying mechanism of circ_0000190, a circRNA i...

    Authors: Gui-Jun Wang, Tian-Yu Yu, Yan-Rong Li, Yang-Jun Liu and Bei-Bei Deng
    Citation: Cancer Cell International 2020 20:351
    Content type: Primary research Published on:

  47. Genetic and epigenetic alterations have been indicated to be closely correlated with the carcinogenesis, DNA methylation is one of most frequently occurring molecular behavior that take place early during this...

    Authors: Qixin Lian, Bo Wang, Lijun Fan, Junqiang Sun, Guilai Wang and Jidong Zhang
    Citation: Cancer Cell International 2020 20:349
    Content type: Primary research Published on:

  48. Long non-coding RNAs (lncRNAs) are a class of endogenous non-coding RNAs of longer than 200 bp that play crucial roles in cancer biology. Here, we assessed the tumorigenic properties of a long noncoding RNA, M...

    Authors: Zhi Zhou, Shan Zhang and Yaqiong Xiong
    Citation: Cancer Cell International 2020 20:348
    Content type: Primary research Published on:

  49. Human AlkB homolog H5 (ALKBH5) is a primary m6A demethylase, which is dysregulated and acts as a biological and pharmacological role in human cancers or non-cancers. ALKBH5 plays a dual role in various cancers...

    Authors: Jinyan Wang, Jinqiu Wang, Quan Gu, Yajun Ma, Yan Yang, Jing Zhu and Quan’an Zhang
    Citation: Cancer Cell International 2020 20:347
    Content type: Review Published on:

  50. Colorectal cancer (CRC) is one of the most common digestive malignant tumors in the world. Ubiquitin-specific peptidase 18 (USP18) plays a regulatory role in tumorigenesis, and abnormal expression of Snail1 is...

    Authors: Fakun Huang, Chengying Zheng, Longkai Huang, Changqing Lin and Jiaxing Wang
    Citation: Cancer Cell International 2020 20:346
    Content type: Primary research Published on:
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Cancer Cell International

ISSN: 1475-2867

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