Variable | Multivariable analysis for RFS | Multivariable analysis for EFS | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p* | HR | 95% CI | p* | |
Age | ||||||
<10 | 1 | Reference | - | 1 | Reference | - |
≥10 | 0.239 | 0.023-2.518 | 0.847 | 0.300 | 0.036-2.466 | 0.244 |
WBC (109/L) | ||||||
<50 | 1 | Reference | - | 1 | Reference | - |
≥50 | 4.677 | 1.715-12.760 | 0.003 | 3.745 | 1.062-13.204 | 0.072 |
BCR-ABL | ||||||
Negative | 1 | Reference | - | 1 | Reference | - |
Positive | 7.190 | 2.022-25.567 | 0.118 | 2.701 | 0.497-14.681 | 0.250 |
TEL-AML1 | ||||||
Negative | 1 | Reference | - | 1 | Reference | - |
Positive | 0.508 | 0.057-4.550 | 0.104 | 0.316 | 0.038-2.629 | 0.059 |
E2A-PBX1 | ||||||
Negative | ||||||
Positive | 1 | Reference | - | 1 | Reference | - |
7.557 | 1.416-40.334 | 0.257 | 3.890 | 0.877-17.248 | 0.222 | |
CNS involvement | ||||||
Absent | 1 | Reference | - | 1 | Reference | - |
Present | 25.259 | 5.124-124.504 | 0.001 | 11.375 | 1.487-86.991 | 0.019 |
rs1544105 | ||||||
CT + TT | 1 | Reference | - | 1 | Reference | - |
CC | 4.992 | 1.550-16.078 | 0.007 | 2.723 | 0.766-9.674 | 0.059 |