Fig. 4

EphB2 knockdown when combined with radiation treatment results in decreased cell viability in medulloblastoma cells. MTT analysis (a, b) and Trypan blue analysis (c, d) show significant decrease in cell viability and decrease in relative percent of total number of cells in both DAOY and UW228 cells when knocked down for EphB2 receptor and combined with 8 Gy dose of radiation compared to other control and experimental groups at 120–144 h post-XRT. Each experiment was replicated two to three times. Data represent mean ± standard error. Student’s t test was used to make comparisons between different groups. *p < 0.05, **p < 0.005, ***p < 0.0005