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Fig. 2 | Cancer Cell International

Fig. 2

From: Targeting deubiquitinating enzymes in cancer stem cells

Fig. 2

Regulating CSCs differentiation and pluripotency by ubiquitination and deubiquitination. Ubiquitination of core stem cell transcription factors or related key proteins by E3 ligases may drive CSCs differentiation, but deubiquitination of those proteins by DUBs mediates stem pluripotency

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