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Fig. 1 | Cancer Cell International

Fig. 1

From: Let-7a induces metabolic reprogramming in breast cancer cells via targeting mitochondrial encoded ND4

Fig. 1

A Differential distribution of mitomiRs upon DOX induced mitochondrial stress in MCF-7 cells. The relative expression of the represented mitoRs was normalized by U6. B Relative expression of let-7a in cellular and mitochondrial RNA isolated from MCF-7 cells. C Mass spectrometric analysis of mitochondrial proteins in let-7a mimic/antisense transfected MCF-7 cells. Results are represented as abundance ratio control/let-7a mimic/antisense. D Predicted target site for let-7a in the ND4 3’-UTR. The p-value was calculated with the download version of RNAhybrid. The data are represented as mean + SD analyzed by unpaired t-test, n = 3. (p < 0.05). ** indicates the level of significance

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Cancer Cell International

ISSN: 1475-2867

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