Table 1 Correlation between CPNE1 mRNA expression and OS and RFS in HCC based on different clinical parameters by Kaplan–Meier plotter

Gender

 Female

1.7 (0.97–3)

0.063

106

2.02 (1.11–3.66)

0.019

 Male

1.74 (1.12–2.71)

0.013

210

0.66 (0.43–1.02)

0.061

Stage

 I

1.66 (0.83–3.32)

0.15

153

0.81 (0.47–1.41)

0.46

 II

2.24 (1–5.03)

0.045

75

0.48 (0.23–0.98)

0.039

 III

2.53 (1.37–4.86)

0.0022

70

2.04 (1.08–3.85)

0.026

 IV

NA

NA

0

NA

NA

Grade

 1

3.16 (1.19–8.41)

0.015

45

4.1 (1.48–11.38)

0.0036

 2

1.77 (1.06–2.96)

0.027

149

1.62 (0.99–2.65)

0.055

 3

1.64 (0.89–3.05)

0.11

107

0.67 (0.39–1.17)

0.16

 4

NA

NA

11

NA

NA

Hepatitis virus

 Yes

1.28 (0.67–2.45)

0.46

139

0.6 (0.35–1.01)

0.053

 None

1.85 (1.15–2.96)

0.0097

143

2.22 (1.33–3.71)

0.0017

Alcohol consumption

 Yes

2.3 (1.18–4.49)

0.012

99

0.65 (0.33–1.29)

0.22

 None

1.83 (1–3.34)

0.046

183

1.56 (1–2.45)

0.05