Skip to main content
Fig. 2 | Cancer Cell International

Fig. 2

From: ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARC

Fig. 2

Perfusion function of vessels within LLC (A&B) and B16F10 (C&D) tissues was significantly impaired after H2O2 treatment when compared to the controls (FITC-lectin+, green; CD31+ endothelial cells, red). Data presented were mean ± SD. After treating with DPI, the proportion of vessels with normal perfusion function was significantly increased (P < 0.01). Differences among two H2O2-treated and DPI-treated groups were tested by ANOVA, with the *** representing p values less than 0.01

LLC: Lewis lung carcinoma cell line; B16F10: murine melanoma cell line; DPI: diphenyleneiodonium; ANOVA: analysis of variance

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us