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Fig. 3 | Cancer Cell International

Fig. 3

From: ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARC

Fig. 3

Ultrasonography showed that VI and VFI within tumor tissues were significantly decreased after the H2O2 treatments when compared to the control group. After treating with DPI, the perfusion signals were significantly upregulated. The yellow arrow indicated the tumor areas; A&B figure was LLC model while C&D figure represented B16F10 model. Data presented were mean ± SD. Differences of VI and VFI among treatment groups were assessed by ANOVA, *** represents p- value less than 0.01

VI: vascularization index; VFI: vascularization flow index; LLC: Lewis lung carcinoma cell line; B16F10: murine melanoma cell line; ANOVA: analysis of variance

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Cancer Cell International

ISSN: 1475-2867

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