Fig. 6From: ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARCIntracellular co-localized expression of phosphorylated Caveolin-1 (red) and SPARC (green) was significantly increased in HUVECs in response to H2O2 treatment relative to the control group. Data presented were mean ± SD. Phosphorylated caveolin-1 and SPARC at different H2O2 treatment time points were compared by ANOVA, * represents p-value less than 0.05, *** represents p-value less than 0.01 HUVECs: human umbilical vein endothelial cells; SPARC: secreted acidic and cysteine-rich protein; ANOVA: analysis of varianceBack to article page