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Fig. 6 | Cancer Cell International

Fig. 6

From: ROS impairs tumor vasculature normalization through an endocytosis effect of caveolae on extracellular SPARC

Fig. 6

Intracellular co-localized expression of phosphorylated Caveolin-1 (red) and SPARC (green) was significantly increased in HUVECs in response to H2O2 treatment relative to the control group. Data presented were mean ± SD. Phosphorylated caveolin-1 and SPARC at different H2O2 treatment time points were compared by ANOVA, * represents p-value less than 0.05, *** represents p-value less than 0.01

HUVECs: human umbilical vein endothelial cells; SPARC: secreted acidic and cysteine-rich protein; ANOVA: analysis of variance

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