Volume 4 Supplement 1

Association for Immunotherapy of Cancer: Cancer Immunotherapy - 2nd Annual Meeting

Meeting abstracts

Association for Immunotherapy of Cancer: Cancer Immunotherapy - 2nd Annual Meeting. Go to conference site.

Mainz, Germany6-7 May 2004

Concatenated PDF 4S1

Page 1 of 2

Bispecific costimulatory molecules for activation of tumor-killing lymphocytes

Authors: R Weth, M Biburger and W Wels

Citation: Cancer Cell International 2004 4(Suppl 1):S1

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Antibody-based immunoreceptors: the impact of signalling domain, binding affinity and costimulation

Authors: A Hombach, C Heuser and H Abken

Citation: Cancer Cell International 2004 4(Suppl 1):S2

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Tolerability and efficacy of the trifunctional antibody removab^® (anti-EpCAM x anti-CD3) in patients with malignant ascites due to ovarian cancer: Results of a phase I/II study

Authors: P Wimberger, A Burges, V Gorbounova, H Sommer, B Schmalfeldt, J Pfisterer, M Lichinitser, A Makhson, M Ströhlein, W Eiermann, M Biakhov, V Moiseenko, A du Bois and R Kimmig

Citation: Cancer Cell International 2004 4(Suppl 1):S3

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HLA DR-directed bispecific single-chain Fv antibodies for lymphoma therapy

Authors: Y Wachter, J Brünke, S Schuster, K Barbin, M Peipp, T Valerius, M Gramatzki, G Fey and R Repp

Citation: Cancer Cell International 2004 4(Suppl 1):S4

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Increased frequency of CTLA4⁺ TGFβ⁺ CD4⁺ CD25⁺ T cells in peripheral blood of patients with chronic lymphatic leukemia and multiple myeloma

Authors: M Beyer, M Kochanek, M von Bergwelt-Baildon, A Popov, J Wolf and JL Schultze

Citation: Cancer Cell International 2004 4(Suppl 1):S5

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MMP-7 inhibits CTL – tumor cell interaction

Authors: S Gregor, V Alla, J Kuball, M Theobald, PR Galle, D Strand and S Strand

Citation: Cancer Cell International 2004 4(Suppl 1):S6

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Genetically modified natural killer cells specifically recognizing the tumor-associated antigens ErbB2/HER2 and EpCAM

Authors: C Uherek, T Müller, T Tonn, B Uherek, H-G Klingemann and WS Wels

Citation: Cancer Cell International 2004 4(Suppl 1):S7

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Rapid functional exhaustion and deletion of cytotoxic T lymphocytes following immunization with recombinant adenovirus

Authors: E Scandella, P Krebs, B Odermatt and B Ludewig

Citation: Cancer Cell International 2004 4(Suppl 1):S8

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High frequency of functionally active Melan-A specific T cells in a patient with progressive immunoproteasome-deficient melanoma

Authors: N Meidenbauer, A Zippelius, MJ Pittet, M Laumer, S Vogl, J Heymann, M Rehli, B Seliger, S Schwarz, F-A Le Gal, PY Dietrich, R Andreesen, P Romero and A Mackensen

Citation: Cancer Cell International 2004 4(Suppl 1):S9

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Adoptive T cell therapy using antigen-specific CD8⁺ T cells for the treatment of patients with metastatic melanoma: a phase I clinical study

Authors: N Meidenbauer, S Vogl, M Laumer, J Heymann, R Andreesen and A Mackensen

Citation: Cancer Cell International 2004 4(Suppl 1):S10

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Large scale in vitro expansion of polyclonal human CD4⁺CD25^high regulatory T cells

Authors: P Hoffmann, R Eder, LA Kunz-Schughart, R Andreesen and M Edinger

Citation: Cancer Cell International 2004 4(Suppl 1):S11

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Reversible HLA multimers (streptamers) for isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens

Authors: J Neudorfer, B Schmidt, K Huster, M Schiemann, T Schmidt, H Wagner, C Peschel, DH Busch and H Bernhard

Citation: Cancer Cell International 2004 4(Suppl 1):S12

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Therapeutic efficacy of RAGE-1 and MAGE-9 peptide specific cytotoxic T cell clones in renal cell carcinoma

Authors: N Oehlrich, M Linnebacher, S Stevanovic and M Zoeller

Citation: Cancer Cell International 2004 4(Suppl 1):S13

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The role of glycosylation as a modulator for signalling strength in T cells

Authors: B Hauptrock, J Kuball, R-H Voss, M Brkic, C Huber and M Theobald

Citation: Cancer Cell International 2004 4(Suppl 1):S14

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Migration of dendritic cells to regional lymph nodes in a vaccination trial

Authors: A Riccobon, R Ridolfi, R Galassi, M Petrini, M Stefanelli, L Fiammenghi, G Giorgetti, A Moretti, L Ridolfi and G Fiorentini

Citation: Cancer Cell International 2004 4(Suppl 1):S15

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Transitory response to vaccination with PSCA-/PSA-peptide loaded, autologous dendritic cells in patients with metastatic, hormone-refractory prostate cancer

Authors: AK Kaskel, R Zeiser, R Jochim, W Schultze-Seemann, CF Waller and H Veelken

Citation: Cancer Cell International 2004 4(Suppl 1):S16

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Vaccination with WT1 induces high frequency memory and effector T cells in peripheral blood and bone marrow associated with complete remission of recurrent AML

Authors: A Letsch, C Scheibenbogen, AM Asemissen, V Mailänder, E Thiel and U Keilholz

Citation: Cancer Cell International 2004 4(Suppl 1):S17

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LUD00-014: Phase I Study of recombinant vaccinia-NY-ESO-1 (rV-NY-ESO-1) and recombinant fowlpox-NY-ESO-1 (rF-NY-ESO-1) in patients with NY-ESO-1 or LAGE positive cancers

Authors: A Bender, J Karbach, A Neumann, M Biskamp, D Jäger, S Gnjatic, E Hoffman, LJ Old, A Knuth and E Jäger

Citation: Cancer Cell International 2004 4(Suppl 1):S18

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Tumor vaccination after allogeneic bone marrow cell reconstitution of the non-myeloablatively conditioned tumor-bearing murine host

Authors: M Zöller

Citation: Cancer Cell International 2004 4(Suppl 1):S19

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Limiting the risk of immunogenicity by identification and removal of T-cell epitopes (DeImmunisation™)

Authors: K Hellendoorn, T Jones, J Watkins, M Baker, A Hamilton and F Carr

Citation: Cancer Cell International 2004 4(Suppl 1):S20

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Proteasome inhibition enhances HLA-class-II antibody-dependent polymorphonuclear cell mediated cytotoxicity against B-cell lymphoma

Authors: B Stockmeyer, M Gramatzki and R Repp

Citation: Cancer Cell International 2004 4(Suppl 1):S21

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Increased effector functions of a monoclonal antibody by glycoform engineering

Authors: G Waxenecker, M Schuster, P Umana, P Brünker, I Froihofer, S Wiederkum, C Schwager, H Klug, GC Mudde, G Himmler and H Loibner

Citation: Cancer Cell International 2004 4(Suppl 1):S22

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Inhibition of signaling via erbB-receptors by antibodies that target the Lewis Y-antigen

Authors: G Waxenecker, M Klinger, H Farhan, M Freissmuth, G Himmler, E Janzek, GC Mudde and H Loibner

Citation: Cancer Cell International 2004 4(Suppl 1):S23

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Release of iC3b from apoptotic pancreatic tumor cells induces tolerance by binding to immature dendritic cells

Authors: J Schmidt, MW Büchler and A Märten

Citation: Cancer Cell International 2004 4(Suppl 1):S24

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Bisphosphonic acid acts as Gamma/Delta T cell activating antigen and has direct cytotoxic activity against pancreatic carcinoma cells

Authors: J Schmidt, Mv Lilienfeld-Toal, MW Büchler and A Märten

Citation: Cancer Cell International 2004 4(Suppl 1):S25

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Regulation of p53 tumor specific immune responses in colorectal cancer patients

Authors: M Büter, M Gasser, T Mueller, D Meyer, N Schramm, A Müller, A Trumpfheller, S Müller, A Thiede and AM Waaga-Gasser

Citation: Cancer Cell International 2004 4(Suppl 1):S26

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Assessment of genes associated with immune activation and regulation in pancreatic cancer patients

Authors: M Gasser, TF Mueller, A Müller, M Becker, N Schramm, M Büter, AM Gassel, A Thiede, H-J Gassel and AM Waaga-Gasser

Citation: Cancer Cell International 2004 4(Suppl 1):S27

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Modulation of tumour directed B cell responses by NK cells

Authors: M Jensen, A Buhl, C Hoyer, S Schmitz, S Tawadros, H Harald-Sedlacek, J Schultze and F Berthold

Citation: Cancer Cell International 2004 4(Suppl 1):S28

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NFκB activation and TGFβ loss signatures are prominent ex vivo responses of peripheral blood mononuclear cells

Authors: T Zander, D Re, S Beyer, M Hellmich, A Popov, I Büchmann, J Wolf, S Debey and JL Schultze

Citation: Cancer Cell International 2004 4(Suppl 1):S29

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Enrichment of functional CD8 memory T cells specific for MUC1 in Bone Marrow of Multiple Myeloma Patients

Authors: M Witzens, C Choi, M Bucur, M Feuerer, N Sommerfeldt, A Trojan, A Ho, V Schirrmacher, H Goldschmidt and P Beckhove

Citation: Cancer Cell International 2004 4(Suppl 1):S30

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Isolated γδ T cells express natural cytotoxicity receptors

Authors: M von Lilienfeld-Toal, J Nattermann, G Feldmann and IGH Schmidt-Wolf

Citation: Cancer Cell International 2004 4(Suppl 1):S31

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The kinetics of accumulation of adoptively transferred ovalbumin-specific T cells in a transgenic, ovalbumin-expressing murine tumor

Authors: R Agger, MS Petersen, CC Fleischer and ME Hokland

Citation: Cancer Cell International 2004 4(Suppl 1):S32

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Tumor-specific murine T cell receptors displace endogenous TCRs in human T cells

Authors: R-H Voss, S Thomas, J Kuball, R Engel, M Brkic, P Guillaume, P Romero, C Huber and M Theobald

Citation: Cancer Cell International 2004 4(Suppl 1):S33

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Induction of leukemia reactive, allogeneic donor lymphocytes

Authors: AK Kaskel, T Portugal, H Veelken and J Finke

Citation: Cancer Cell International 2004 4(Suppl 1):S34

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Identification of a melanoma-associated chondroitin sulfate proteoglycan (MCSP) peptide recognized by CD4⁺ T lymphocytes on human melanoma cells

Authors: CS Erfurt, C Heirman, K Thielemans, G Schuler and ES Schultz

Citation: Cancer Cell International 2004 4(Suppl 1):S35

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Chimeric carrier proteins for targeted delivery of tumor antigens to professional antigen presenting cells

Authors: F Rohrbach, R Weth, M Kursar, H-W Mittrücker and W Wels

Citation: Cancer Cell International 2004 4(Suppl 1):S36

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Particulate antigenic structures: highly immunogenic carriers for T cell epitopes derived from tumour antigens

Authors: M Brinkman, J Walter, S Grein, MJW Thies, C Reiser and J Hess

Citation: Cancer Cell International 2004 4(Suppl 1):S37

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Development, monitoring and first immunological results of a phase I/II vaccination trial using genetically modified allogeneic breast cancer cells

Authors: B Gückel, S Stumm, C Rentzsch, S Kayser, I Gruber, A Marmé, J Huober, F Autschbach, S Meuer and D Wallwiener

Citation: Cancer Cell International 2004 4(Suppl 1):S38

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Dendritic cell-based immunotherapy of hormone refractory prostate carcinoma (HRPCa) – a pilot trial

Authors: B Hildenbrand, A Langenkamp, B Sauer, C Stoll, O Constantiniu, R Leo, C Unger and M Azemar

Citation: Cancer Cell International 2004 4(Suppl 1):S39

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The European Searchable Tumour Cell and Databank, ESTDAB, as a tool for research in cancer immunology

Authors: L Müller, D Schadendorf, S Stevanovic, A Knights, E Badalian, L Wedel and G Pawelec

Citation: Cancer Cell International 2004 4(Suppl 1):S40

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Efficient in vitro expression of human reverse transcriptase (hTERT) in dendritic cells of lung cancer patients using RNA electrotransfection

Authors: A-K Brill, W Klapper, U Weingartz, I Bolz, A Heiser, D Kabelitz, M Kneba and B Gahn

Citation: Cancer Cell International 2004 4(Suppl 1):S41

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Parvovirus H1-induced tumor cell death enhances human immune response via crosspresentation of dendritic cells

Authors: M Zeidler, J Cornelis, T Woelfel, J Rommeleare, PR Galle, M Heike and M Moehler

Citation: Cancer Cell International 2004 4(Suppl 1):S42

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Optimizing the antigen loading of dendritic cells with exogenous peptides

Authors: ES Schultz, D Dieckmann, B Ring and G Schuler

Citation: Cancer Cell International 2004 4(Suppl 1):S43

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Phase I/II study of vaccination with immature and mature dendritic cells in patients with melanoma and renal cell carcinoma

Authors: M Petrini, L Fiammenghi, L Ridolfi, M Stefanelli, G Migliori, C Brolli, A Riccobon and R Ridolfi

Citation: Cancer Cell International 2004 4(Suppl 1):S44

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Survival and homing of ex vivo expanded donor derived dendritic cells after allogeneic BMT

Authors: C Schimmelpfennig, S Schulz, C Arber, J Baker, I Tarner, J McBride, CG Fathman, C Contag and R Negrin

Citation: Cancer Cell International 2004 4(Suppl 1):S45

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PBMCs transfected with RNActive stimulate specific T-cells

Authors: R Teufel, J-P Carralot, B Scheel, I Hörr and Steve Pascolo

Citation: Cancer Cell International 2004 4(Suppl 1):S46

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Addition of histamine to IL-2 treatment augments T1 cell-function in melanoma patients in vivo: results from a randomized clinical trial of IL-2 with or without histamine (MP 104)

Authors: AM Asemissen, C Scheibenbogen, A Letsch, K Hellstrand, K Gehlsen, E Thiel and U Keilholz

Citation: Cancer Cell International 2004 4(Suppl 1):S47

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Peptide vaccination induces specific effector and memory T cells but fails to enhance preexisting T cell immunity

Authors: A Letsch, U Keilholz, D Nagorsen, AM Asemissen, E Thiel and C Scheibenbogen

Citation: Cancer Cell International 2004 4(Suppl 1):S48

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Biological characterization of CD40-activated B cells as a prerequisite for their use as cellular adjuvant in cancer vaccines

Authors: MS von Bergwelt-Baildon, B Maecker, F Fiore, LM Nadler and JL Schultze

Citation: Cancer Cell International 2004 4(Suppl 1):S49

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Identification of a novel epitope derived from the cancer-germline antigen, HAGE, displaying both in-vitro and in-vivo immunogenicity

Authors: Ashley Knights, Stephanie McArdle, Ludmila Müller, Robert Rees and Graham Pawelec

Citation: Cancer Cell International 2004 4(Suppl 1):S50

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