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  2. Runt related transcription factor3 (RUNX3) is considered as a tumor suppressor gene (TSG) that functions through the TGF-β dependent apoptosis. Promoter methylation of the CpG islands of RUNX3 and overexpressi...

    Authors: Asad Ur Rehman, Mohammad Askandar Iqbal, Real Sumayya Abdul Sattar, Snigdha Saikia, Mohammad Kashif, Wasif Mohammad Ali, Subhash Medhi, Sundeep Singh Saluja and Syed Akhtar Husain
    Citation: Cancer Cell International 2020 20:445
    Content type: Primary research Published on:

  3. Urological cancers are responsible for thousands of cancer-related deaths around the world. Despite all developments in therapeutic approaches for cancer therapy, the absence of efficient treatments is a criti...

    Authors: Mohammad Hossein Pourhanifeh, Azam Hosseinzadeh, Kobra Bahrampour Juybari and Saeed Mehrzadi
    Citation: Cancer Cell International 2020 20:444
    Content type: Review Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:466

  4. The microRNA miR-221-3p has previously been found to be an underlying biomarker of pancreatic cancer. However, the mechanisms of miR-221-3p underlying its role in pancreatic cancer pathogenesis, proliferation ...

    Authors: Xuejiao Wu, Jia Huang, Zilin Yang, Ying Zhu, Yongping Zhang, Jiancheng Wang and Weiyan Yao
    Citation: Cancer Cell International 2020 20:443
    Content type: Primary research Published on:

  5. Acute lymphoblastic leukemia (ALL) is an aggressive hematopoietic malignancy that is most commonly observed in children. Alantolactone (ALT) has been reported to exhibit anti-tumor activity in different types ...

    Authors: Ce Shi, Wenjia Lan, Zhenkun Wang, Dongguang Yang, Jia Wei, Zhiyu Liu, Yueqiu Teng, Mengmeng Gu, Tian Yuan, Fenglin Cao, Jin Zhou and Yang Li
    Citation: Cancer Cell International 2020 20:442
    Content type: Primary research Published on:

  7. It has reported that long non-coding RNAs (lncRNAs) exerted regulatory functions by targeting specific genes through a competing endogenous RNA (ceRNA) pathway. LncRNA OIP5-AS1 has been identified as a tumor-e...

    Authors: Yu Wang, Lei Dou, Yun Qin, Huiyuan Yang and Peng Yan
    Citation: Cancer Cell International 2020 20:440
    Content type: Primary research Published on:

  8. KLF5 is a member of the Kruppel-like factor, subfamily of zinc finger proteins that are involved in cancers. KLF5 functions as a transcription factor and regulates the diverse protein-coding genes (PCGs) in color...

    Authors: Qi Liao, Linbo Chen, Ning Zhang, Yang Xi, Shiyun Hu, Derry Minyao Ng, Fatma Yislam Hadi Ahmed, Guofang Zhao, Xiaoxiang Fan, Yangyang Xie, Xiaoyu Dai, Yanping Jin, Jiaxin Ge, Changzheng Dong, Xinjun Zhang and Junming Guo
    Citation: Cancer Cell International 2020 20:439
    Content type: Primary research Published on:

  9. Non-small cell lung cancer (NSCLC) is a deadly human malignancy, and previous studies support the contribution of microRNAs (miRNAs) to cancer assessment. It has been reported that miR-1231 can be used as a bi...

    Authors: Jing Li, Jialiang Xu, Zhijun Cao, Shouzuo Du and Luyu Zhang
    Citation: Cancer Cell International 2020 20:438
    Content type: Primary research Published on:

  12. Cholangiocarcinoma (CCA) is a rare tumor that arises from cholangiocytes, the epithelial cells of the bile duct. The tumor is characterized by insidious onset, high degree of malignancy, poor prognosis and hig...

    Authors: Mingzhen Bai, Wenkang Fu, Gang Su, Jie Cao, Long Gao, Chongfei Huang, Haidong Ma, Jinduo Zhang, Ping Yue, Bing Bai, Yanyan Lin, Wenbo Meng and Xun Li
    Citation: Cancer Cell International 2020 20:435
    Content type: Review Published on:

  13. The genetic variants of the ARID5B gene have recently been reported to be associated with disease susceptibility and treatment outcome in childhood acute lymphoblastic leukemia (ALL). However, few studies have ex...

    Authors: Minori Tamai, Meixian Huang, Keiko Kagami, Masako Abe, Shinpei Somazu, Tamao Shinohara, Daisuke Harama, Atsushi Watanabe, Koshi Akahane, Kumiko Goi, Kanji Sugita, Hiroaki Goto, Masayoshi Minegishi, Shotaro Iwamoto and Takeshi Inukai
    Citation: Cancer Cell International 2020 20:434
    Content type: Primary research Published on:

  14. Gastric cancer (GC) is one of the high-risk cancers that lacks effective methods for prognosis prediction. Therefore, we searched for immune cells related to the prognosis of GC and studied the role of related...

    Authors: Gang Hu, Ningjie Sun, Jiansong Jiang and Xiansheng Chen
    Citation: Cancer Cell International 2020 20:433
    Content type: Primary research Published on:

  15. Lung adenocarcinoma is metastatic cancer with a high mortality rate. Circular RNAs (circRNAs) are a type of noncoding RNA and play a vital role in cancer progression. However, the expression and function of ci...

    Authors: Yongyong Yan, Jiantian Yang, Janak L. Pathak, Haiyan Wang, Jun Zha, Yongxiang Wei, Haibo Tang and Linhu Ge
    Citation: Cancer Cell International 2020 20:432
    Content type: Primary research Published on:

  16. Circular RNA (circRNA), an novel type of non-coding RNA, could interact with miRNA and protein molecules to regulate the occurrence and progression of hepatocellular carcinoma (HCC). However, little is known a...

    Authors: Yabin Yu, Suyang Han, Meng Li, Yan Song and Fuzhen Qi
    Citation: Cancer Cell International 2020 20:431
    Content type: Primary research Published on:

  17. Growing evidence has revealed the involvement of circular RNAs (circRNAs) in numerous carcinogenesis. However, the role of circRNAs in the cancer biology of colorectal cancer (CRC) remains vague.

    Authors: Jiabin Du, Jianhua Xu, Junxing Chen, Weinan Liu, Pengcheng Wang and Kai Ye
    Citation: Cancer Cell International 2020 20:430
    Content type: Primary research Published on:

  18. Tumor necrosis factor receptor (TNFR)-related factors (TRAFs) are important linker molecules in the tumor necrosis factor superfamily (TNFSF) and the Toll-like/interleukin-1 receptor (TLR/ILR) superfamily. The...

    Authors: Jiaoduan Li, Nian Liu, Ling Tang, Bei Yan, Xiang Chen, Jianglin Zhang and Cong Peng
    Citation: Cancer Cell International 2020 20:429
    Content type: Review Published on:

  19. Glioma is one prevalent malignant tumor originates from the central nervous system. Dysregulation of long non-coding RNAs (lncRNAs) has been found to be a molecular signature behind the pathology of a variety ...

    Authors: Jianguo Qi, Zhengrui Wang, Zhensheng Zhao and Lijun Liu
    Citation: Cancer Cell International 2020 20:428
    Content type: Primary research Published on:

  20. Circular RNAs (circRNAs) are a novel class of noncoding RNAs. Increasing evidence indicates that circRNAs play an important role in the occurrence and development of tumors. However, the role of circRNA hsa_ci...

    Authors: Liang Jing, Junhui Wu, Xiaocheng Tang, Min Ma, Fei Long, Buning Tian and Changwei Lin
    Citation: Cancer Cell International 2020 20:427
    Content type: Primary research Published on:

  21. The methylation of the CpG islands of the LINE-1 promoter is a tight control mechanism on the function of mobile elements. However, simultaneous quantification of promoter methylation and transcription of LINE...

    Authors: Milad Shademan, Khadijeh Zare, Morteza Zahedi, Hooman Mosannen Mozaffari, Hadi Bagheri Hosseini, Kamran Ghaffarzadegan, Ladan Goshayeshi and Hesam Dehghani
    Citation: Cancer Cell International 2020 20:426
    Content type: Primary research Published on:

  22. Dysregulation of fatty acid (FA) metabolism is involved in hepatocellular carcinoma (HCC) development. Non-POU domain-containing octamer binding protein (NONO), known as the component of nuclear paraspeckles, ...

    Authors: Hongda Ding, Junpeng Liu, Caibin Wang and Yang Su
    Citation: Cancer Cell International 2020 20:425
    Content type: Primary research Published on:

  23. Cervical cancer (CC) is the one of most common malignant gynecological tumors, which is characterized with the high mortality and recurrence rate. Previous studies have elucidated the oncogenic role of small n...

    Authors: Jin Liu, Xiaojiao Liu and Rong Li
    Citation: Cancer Cell International 2020 20:424
    Content type: Primary research Published on:

  25. Krüppel-like factor 8 (KLF8), a cancer-promoting factor that regulates critical gene transcription and cellular cancer-related events, has been implicated in tumor development and progression. However, the fun...

    Authors: Ming-Da Wang, Hao Xing, Chao Li, Lei Liang, Han Wu, Xin-Fei Xu, Li-Yang Sun, Meng-Chao Wu, Feng Shen and Tian Yang
    Citation: Cancer Cell International 2020 20:422
    Content type: Primary research Published on:

  26. New screening techniques may affect the optimal approaches for the prevention of cervical cancer. We evaluated the cost-effectiveness and accuracy of alternative screening strategies to provide evidence for ce...

    Authors: Binhua Dong, Lihua Chen, Wenyu Lin, Yingying Su, Xiaodan Mao, Diling Pan, Guanyu Ruan, Huifeng Xue, Yafang Kang and Pengming Sun
    Citation: Cancer Cell International 2020 20:421
    Content type: Primary research Published on:

  27. Most cancer cells exhibit increased glycolysis and use this metabolic pathway cell growth and proliferation. Targeting cancer cells’ metabolism is a promising strategy in inhibiting cancer cell progression. We...

    Authors: Ahmed Ghdhban Al-Ziaydi, Ahmed Majeed Al-Shammari, Mohammed I. Hamzah, Haider Sabah kadhim and Majid Sakhi Jabir
    Citation: Cancer Cell International 2020 20:420
    Content type: Primary research Published on:

  28. Glioblastoma (GBM) is a common and aggressive primary brain tumor, and the prognosis for GBM patients remains poor. This study aimed to identify the key genes associated with the development of GBM and provide...

    Authors: Wei-cheng Lu, Hui Xie, Ce Yuan, Jin-jiang Li, Zhao-yang Li and An-hua Wu
    Citation: Cancer Cell International 2020 20:419
    Content type: Primary research Published on:

  29. Tribbles pseudokinase 3 (TRIB3) protein is a pseudokinase which plays an important role in cellular stress, metabolism, and tumor progression. However, the expression and function of TRIB3 in ovarian cancer is...

    Authors: Shuang Wang, Caixia Wang, Xiao Li, Yuexin Hu, Rui Gou, Qian Guo, Xin Nie, Juanjuan Liu, Liancheng Zhu and Bei Lin
    Citation: Cancer Cell International 2020 20:418
    Content type: Primary research Published on:

  30. Immunocompetent animal models are required to study tumor-host interactions, immunotherapy, and immunotherapeutic combinations, however the currently available immunocompetent lung cancer models have substanti...

    Authors: Kyle Nolan, Gregory Verzosa, Tim Cleaver, Darinee Tippimanchai, Lisa N. DePledge, Xiao-Jing Wang, Christian Young, Anh Le, Robert Doebele, Howard Li and Stephen P. Malkoski
    Citation: Cancer Cell International 2020 20:417
    Content type: Primary research Published on:

  31. This study aimed to investigate the relationship among miR-145-5p, ANGPT2 and the NOD_LIKE_RECEPTOR pathway, thereby revealing the molecular mechanism of these three factors underlying the proliferation, migratio...

    Authors: Kai Zhou, Binbin Song, Ming Wei, Jubo Fang and Yufen Xu
    Citation: Cancer Cell International 2020 20:416
    Content type: Primary research Published on:

  32. Oral squamous cell carcinoma (OSCC) is a common kind of squamous cell carcinoma of the head and neck, which is a threat to public health. Long noncoding RNAs (lncRNAs) are associated with the development of va...

    Authors: Su-Wei Fu, Yan Zhang, Shen Li, Zhi-Yan Shi, Juan Zhao and Qing-Li He
    Citation: Cancer Cell International 2020 20:415
    Content type: Primary research Published on:

  33. Long non-coding RNAs (lncRNAs) play a vital role in the genesis and development of human cancer. LncRNA MIR99AHG has been reported to be upregulated in acute myeloid leukemia (AML); however, its function in ga...

    Authors: Qingyang Meng, Xiangjun Wang, Tongqing Xue, Qiangfang Zhao, Wei Wang and Kun Zhao
    Citation: Cancer Cell International 2020 20:414
    Content type: Primary research Published on:

  35. Endometrial cancer (EC) is a common malignancy of the female reproductive system. Circular RNAs (circRNAs) were demonstrated to exert critical roles in cancers, including EC. This study aimed to investigate th...

    Authors: Youjuan Jia, Meijuan Liu and Shuxia Wang
    Citation: Cancer Cell International 2020 20:412
    Content type: Primary research Published on:

  36. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Chia-Chen Hsu, Yu-Fu Su, Kuo-Yang Tsai, Feng-Chih Kuo, Chi-Fu Chiang, Chu-Yen Chien, Ying-Chen Chen, Chien-Hsing Lee, Yu-Chiao Wu, Kun Wang, Shyun-Yeu Liu and Yi-Shing Shieh
    Citation: Cancer Cell International 2020 20:410
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2020 20:300

  37. Diagnosis of metastatic castrate resistant prostate cancer (mCRPC) with current biomarkers is difficult and often results in unnecessary invasive procedures as well as over-diagnosis and over-treatment. There ...

    Authors: Shengri Tian, Zhen Lei, Zuo Gong, Zhonghai Sun, Dongyuan Xu and Minhu Piao
    Citation: Cancer Cell International 2020 20:409
    Content type: Review Published on:

  38. Nasopharyngeal carcinoma (NPC) is an epithelial malignancy with high morbidity rates in the east and southeast Asia. The molecular mechanisms of NPC remain largely unknown. We explored the pathogenesis, potent...

    Authors: Yuanji Xu, Xinyi Huang, Wangzhong Ye, Yangfan Zhang, Changkun Li, Penggang Bai, Zhizhong Lin and Chuanben Chen
    Citation: Cancer Cell International 2020 20:408
    Content type: Primary research Published on:

  39. Oral squamous cell carcinoma (OSCC) is a more common cancer in the world. Emerging evidence suggests that circular RNAs (circRNAs) participate in the progression of OSCC. However, the role of circ_0000140 in O...

    Authors: Jia Guo, Yuanyuan Su and Meng Zhang
    Citation: Cancer Cell International 2020 20:407
    Content type: Primary research Published on:

  40. Hepatocellular carcinoma (HCC) is a high mortality disease, the fifth most general cancer worldwide, and the second leading to cancer-related deaths, with more than 500,000 new patients diagnosed each year. Fi...

    Authors: Zeng-hong Wu and Dong-liang Yang
    Citation: Cancer Cell International 2020 20:406
    Content type: Primary research Published on:

  41. Despite being one of the leading cancer types in the world, the diagnosis of oral cancer and its suitable therapeutic options remain limited. This study aims to investigate the single and chemosensitizing effe...

    Authors: In-Hyoung Yang, Seung-Hyun Hong, Minjung Jung, Chi-Hyun Ahn, Hye-Jung Yoon, Seong Doo Hong, Sung-Dae Cho and Ji-Ae Shin
    Citation: Cancer Cell International 2020 20:405
    Content type: Primary research Published on:

  42. Circular RNAs (circRNAs) play vital roles in hepatocellular carcinoma development. However, the role and mechanism of circRNA hsa_circ_0000517 (circ_0000517) in hepatocellular carcinoma development were largel...

    Authors: Shuwei He, Jianzeng Yang, Shitao Jiang, Yuan Li and Xingmin Han
    Citation: Cancer Cell International 2020 20:404
    Content type: Primary research Published on:

  43. Long non-coding RNA (lncRNA) BM742401 is a tumor suppressor in gastric cancer and chronic lymphocytic leukemia. As the promoter and coding region of BM742401 are fully embedded in a CpG island, we hypothesized th...

    Authors: Zhenhai Li, Shaji Kumar, Dong-Yan Jin, George A. Calin, Wee-Joo Chng, Kam-Leung Siu, Ming-Wai Poon and Chor Sang Chim
    Citation: Cancer Cell International 2020 20:403
    Content type: Primary research Published on:

  46. Breast cancer (BC) is the most common malignancy among women. Emerging studies have demonstrated that circular RNA (circRNA) zinc finger RNA binding protein (circZFR) serves as a crucial regulator in many huma...

    Authors: Zhuo Chen, Fang Wang, Youyi Xiong, Nan Wang, Yuanting Gu and Xinguang Qiu
    Citation: Cancer Cell International 2020 20:400
    Content type: Primary research Published on:

  47. Iron metabolism disorder is closely associated with several malignant tumors, however the mechanisms underlying iron and the carcinogenesis in osteosarcoma are not yet well understood.

    Authors: Shuo Ni, Yanbin Kuang, Yin Yuan and Baoqing Yu
    Citation: Cancer Cell International 2020 20:399
    Content type: Primary research Published on:

  48. Oral squamous cell carcinoma (OSCC), a form of head and neck squamous cell carcinoma (HNSCC) has a poor 5-year survival rate. OSCC patients are often treated with cisplatin but resistance to chemotherapy is of...

    Authors: Xiao-han Li, Dan Li, Chang Liu, Ming-ming Zhang, Xiao-jiao Guan and Ya-ping Fu
    Citation: Cancer Cell International 2020 20:398
    Content type: Primary research Published on:

  49. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Tong Li, Qiaofei Liu, Ronghua Zhang, Quan Liao and Yupei Zhao
    Citation: Cancer Cell International 2020 20:397
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2020 20:341

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Cancer Cell International

ISSN: 1475-2867

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