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  2. Over the years, long non-coding RNAs (lncRNAs) have been clarified in malignancies, this research was focused on the role of lncRNA cartilage injury-related (lncRNA-CIR) in osteosarcoma cells.

    Authors: Shiwei Liu, Jingchao Li, Liang Kang, Yueyang Tian and Yuan Xue
    Citation: Cancer Cell International 2019 19:349
    Content type: Primary research Published on:

  3. Casticin, an isoflavone compound extracted from the herb Fructus Viticis, has demonstrated anti-inflammatory and anticancer activities and properties. The aim of this study was to investigate the effects and m...

    Authors: Jingxian Liu, Jinghong Yang, Yuhe Hou, Zhenwei Zhu, Jie He, Hao Zhao, Xidong Ye, Dengke Li, Zhaohui Wu, Zhongxi Huang, Bingtao Hao and Kaitai Yao
    Citation: Cancer Cell International 2019 19:348
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2021 21:138

  4. Ovarian cancer (OC) is a gynecological malignancy with a high mortality. Cisplatin-based treatment is the typical treatment regimen for OC patients; however, it may cause unfavorable resistance. The current st...

    Authors: Hua Guo, Chunfang Ha, Hui Dong, Zhijuan Yang, Yuan Ma and Yonghui Ding
    Citation: Cancer Cell International 2019 19:347
    Content type: Primary research Published on:

  5. Treatments that generate T cell-mediated immunity to a patient’s unique neoantigens are the current holy grail of cancer immunotherapy. In particular, treatments that do not require cumbersome and individualiz...

    Authors: Stephen M. Shaw, Jenny Middleton, Kim Wigglesworth, Amber Charlemagne, Oliver Schulz, Melanie S. Glossop, Giles F. Whalen, Robert Old, Mike Westby, Chris Pickford, Rinat Tabakman, Irit Carmi-Levy, Abi Vainstein, Ella Sorani, Arik A. Zur and Sascha A. Kristian
    Citation: Cancer Cell International 2019 19:346
    Content type: Primary research Published on:

  6. Glioblastoma has been seen as the most common malignancy of brain tumor. Emerging reports has claimed that SNHG29 (LRRC75A-AS1) was involved in several biological processes via modulation of signaling pathway,...

    Authors: Lizhang Han, Zhonggang Li, Yuquan Jiang, Zheng Jiang and Ling Tang
    Citation: Cancer Cell International 2019 19:345
    Content type: Primary research Published on:

  7. Gastric cancer (GC) is one of the most common gastrointestinal malignancies worldwide. Emerging evidence indicates that hyperglycemia promotes tumor progression, especially the processes of migration, invasion...

    Authors: Xin Xu, Bang Chen, Shaopu Zhu, Jiawei Zhang, Xiaobo He, Guodong Cao and Bo Chen
    Citation: Cancer Cell International 2019 19:344
    Content type: Primary research Published on:

  8. The progression of ductal carcinoma in situ (DCIS) into invasive ductal carcinoma (IDC) is prevented by normal breast myoepithelial cells. Studies have suggested that EMT-associated genes were enriched in IDC ...

    Authors: Li Wang, Cong Xu, Xia Liu, Yang Yang, Lu Cao, Guomin Xiang, Fang Liu, Shuling Wang, Jing Liu, Qingxiang Meng, Jiao Jiao and Yun Niu
    Citation: Cancer Cell International 2019 19:343
    Content type: Primary research Published on:

  9. As a novel type of isothiocyanate derived from radish seeds from cruciferous vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various important biological effects, such as anti-oxid...

    Authors: Chengjuan Zhang, Junxia Zhang, Qiong Wu, Benling Xu, Guoguo Jin, Yan Qiao, Simin Zhao, Yang Yang, Jinwen Shang, Xiaofang Li and Kangdong Liu
    Citation: Cancer Cell International 2019 19:342
    Content type: Primary research Published on:

  10. Circulating tumor cells (CTCs) are a rare subset of cells found in the blood of patients with solid tumors, which function as a seed for metastases. Cancer cells metastasize through the bloodstream either as s...

    Authors: Chang Yang, Bai-Rong Xia, Wei-Lin Jin and Ge Lou
    Citation: Cancer Cell International 2019 19:341
    Content type: Review Published on:

  11. Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, especially in China, with high metastasis and poor prognosis. Recently, as the core component of the polycomb repressive complex...

    Authors: Xiaonian Zhu, Wei Luo, Chunhua Bei, Juan Kong, Shidong Zhang, Yuanyuan Fu, Di Li and Shengkui Tan
    Citation: Cancer Cell International 2019 19:340
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2020 20:486

  12. Ovarian cancer is one of the leading causes of female death worldwide, with a poor prognosis of advanced patients. Sevoflurane, a volatile anesthetic commonly used in clinical operations, has been reported to ...

    Authors: Chuanfeng Zhang, Baosheng Wang, Xiuqin Wang, Xiugui Sheng and Yongchun Cui
    Citation: Cancer Cell International 2019 19:339
    Content type: Primary research Published on:

  13. The dysregulation of circABCB10 may play an critical role in tumor progression. However, its function in liver cancer (HCC) is still unclear. Therefore, this experimental design is based on circABCB10 to explo...

    Authors: Yu Fu, Limin Cai, Xuexue Lei and Dunwei Wang
    Citation: Cancer Cell International 2019 19:338
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2020 20:485

  14. Muscle-invasive bladder cancer (MIBC) is originated in the muscle wall of the bladder, and is the ninth most common malignancy worldwide. However, there are no reliable, accurate and robust gene signatures for...

    Authors: Ping-Bao Zhang, Zi-Li Huang, Yong-Hua Xu, Jin Huang, Xin-Yu Huang and Xiu-Yan Huang
    Citation: Cancer Cell International 2019 19:337
    Content type: Primary research Published on:

  15. Autophagy is an evolutionarily conserved process through which cells degrade and recycle cytoplasm. The relation among autophagy, apoptosis and tumor is highly controversial until now and the molecular mechani...

    Authors: Jing Liu, Shuaiyu Long, Huanan Wang, Nannan Liu, Chuchu Zhang, Lingling Zhang and Yingjie Zhang
    Citation: Cancer Cell International 2019 19:336
    Content type: Primary research Published on:

  16. The high prevalence of alternative splicing among genes implies the importance of genomic complexity in regulating normal physiological processes and diseases such as gastric cancer (GC). The standard form of ...

    Authors: Wei-zhao Peng, Ji-xi Liu, Chao-feng Li, Ren Ma and Jian-zheng Jie
    Citation: Cancer Cell International 2019 19:335
    Content type: Primary research Published on:

  17. Endometrial carcinoma (EC) accounts for 5.8% of all cancers in Saudi females. Although most ECs are sporadic, 2–5% tend to be familial, being associated with Lynch syndrome and Cowden syndrome. In this study, ...

    Authors: Abdul K. Siraj, Sandeep Kumar Parvathareddy, Rong Bu, Kaleem Iqbal, Sarah Siraj, Tariq Masoodi, Rica Micaela Concepcion, Laila Omar Ghazwani, Ismail AlBadawi, Fouad Al-Dayel and Khawla S. Al-Kuraya
    Citation: Cancer Cell International 2019 19:334
    Content type: Primary research Published on:

  19. Abiraterone and MDV3100 are two effective anticancer agents for prostate cancer, however, the mechanism of their downstream action remains undefined.

    Authors: Jingli Han, Junhua Zhang, Wei Zhang, Dalei Zhang, Ying Li, Jinsong Zhang, Yaqun Zhang, Tongxiang Diao, Luwei Cui, Wenqing Li, Fei Xiao, Ming Liu and Lihui Zou
    Citation: Cancer Cell International 2019 19:332
    Content type: Primary research Published on:

  21. Abnormal activation of the classic Wnt signaling pathway is closely related to the occurrence of epithelial cancers. B-cell lymphoma 9 (BCL9), a transcription factor, is a novel oncogene discovered in the clas...

    Authors: Jing Wang, Mingjun Zheng, Liancheng Zhu, Lu Deng, Xiao Li, Linging Gao, Caixia Wang, Huimin Wang, Juanjuan Liu and Bei Lin
    Citation: Cancer Cell International 2019 19:330
    Content type: Primary research Published on:

  22. Hepatocellular carcinoma (HCC) is the most prevalent type of malignant liver disease worldwide. Molecular changes in HCC collectively contribute to Wnt/β-catenin, as a tumor proliferative signaling pathway, to...

    Authors: Jafar Ai, Neda Ketabchi, Javad Verdi, Nematollah Gheibi, Hossein Khadem Haghighian and Maria Kavianpour
    Citation: Cancer Cell International 2019 19:329
    Content type: Review Published on:

  23. Circular RNA Itchy E3 ubiquitin protein ligase (Circ-ITCH) is significantly down-regulated in various kinds of tumors, however, the mechanisms of action and functions of circITCH gene in prostate cancer (PC) a...

    Authors: Xuegang Wang, Rong Wang, Zhun Wu and Peide Bai
    Citation: Cancer Cell International 2019 19:328
    Content type: Primary research Published on:

  24. The aim of this study was to investigate the regulatory network of lncRNAs as competing endogenous RNAs (ceRNA) in bladder urothelial carcinoma (BUC) based on gene expression data derived from The Cancer Genom...

    Authors: Jiawu Wang, Chengyao Zhang, Yan Wu, Weiyang He and Xin Gou
    Citation: Cancer Cell International 2019 19:327
    Content type: Primary research Published on:

  25. Osteosarcoma (OS) is still a disease with high mortality from malignant tumors in children and adolescents. Due to its poor treatment, this study explored the involvement of lncRNA ZFAS1/microRNA-135a (miR-135...

    Authors: Zilong Zhao, Xiafei Lin, Yunhui Tong and Wenxia Li
    Citation: Cancer Cell International 2019 19:326
    Content type: Primary research Published on:

  26. The large involvement of long non-coding RNAs (LncRNAs) in the biological progression of numerous cancers has been reported. The function of lncRNA KCNQ1OT1 in bladder cancer (BC) remains largely unknown. This...

    Authors: Jingyu Wang, Hao Zhang, Jie Situ, Mingzhao Li and Hua Sun
    Citation: Cancer Cell International 2019 19:325
    Content type: Primary research Published on:

  27. Spindle and kinetochore associated protein 1 (SKA1) is a protein involved in chromosome congression and mitosis. It has been found to be upregulated and oncogenic in several human cancers. Herein, we investiga...

    Authors: Xizhao Wang, Yu Zeng, Mingfeng Zhou, Xian Zhang, Anqi Xu, Jie Lin, Zhiyong Wu, Cheng Xie, Jie Luo, Shengfeng Ding, Zhengming Zhan, Hao Long and Ye Song
    Citation: Cancer Cell International 2019 19:324
    Content type: Primary research Published on:

  28. There is growing evidence of the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). The objective was to discuss whether exosomal lncRNA HNF1A-AS1 impacted drug resistance in CC via binding to mic...

    Authors: Xiaoqiong Luo, Jingxi Wei, Feng-lian Yang, Xiao-xia Pang, Feng Shi, Yu-xia Wei, Bi-yun Liao and Jun-li Wang
    Citation: Cancer Cell International 2019 19:323
    Content type: Primary research Published on:

  29. Autologous tumor-infiltrating lymphocytes (Tils) immunotherapy is a promising treatment in patients with advanced hepatocellular cancer. Although Tils treatment has shown great promise, their persistence and t...

    Authors: Benling Xu, Long Yuan, Guangyu Chen, Tiepeng Li, Jinxue Zhou, Chengjuan Zhang, Peng Qin, Musleh M. Muthana, Shengdian Wang, Xuexiang Du and Quanli Gao
    Citation: Cancer Cell International 2019 19:322
    Content type: Primary research Published on:

  30. Since FTO was recognized as the first m6A demethylase, the understanding of its biological function has been widely expanded. However, the role of FTO in cervical cancer tumorigenesis remains unclear.

    Authors: Dongling Zou, Lei Dong, Chenying Li, Zhe Yin, Shuan Rao and Qi Zhou
    Citation: Cancer Cell International 2019 19:321
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:423

  31. Pancreatic cancer (PC) is one of the deadliest cancers about the digestive system. Recent researches have validated that long non-coding RNAs (lncRNAs) play vital roles in various cancers, while the function o...

    Authors: Luyang Zhang, Yunjian Wang, Ling Zhang, Guohua You, Congyu Li, Bo Meng, Minghe Zhou and Min Zhang
    Citation: Cancer Cell International 2019 19:320
    Content type: Primary research Published on:

  32. Osteosarcoma is the most common bone tumors which consisted of malignant mesenchymal cells generating osteoid and immature bone. It has been showed that osteosarcoma is common in children and adolescents and s...

    Authors: Hadis Fathizadeh, Hamed Mirzaei and Zatollah Asemi
    Citation: Cancer Cell International 2019 19:319
    Content type: Review Published on:

  33. This study aimed to investigate the prognostic value of the potential biomarker collagen triple helix repeat containing 1 (CTHRC1) in lung adenocarcinoma (LUAD) patients.

    Authors: Yangshan Chen, Yu Sun, Yongmei Cui, Yiyan Lei, Neng Jiang, Wenting Jiang, Han Wang, Lili Chen, Jiping Luo, Yanyang Chen, Kejing Tang, Chengzhi Zhou and Zunfu Ke
    Citation: Cancer Cell International 2019 19:318
    Content type: Primary research Published on:

  34. Cisplatin plus pemetrexed combination therapy is considered the standard treatment for patients with advanced, non-squamous, non-small-cell lung cancer (NSCLC). However, advanced NSCLC has a 5-year survival ra...

    Authors: Yanyun Gao, Patrick Dorn, Shengchen Liu, Haibin Deng, Sean R. R. Hall, Ren-Wang Peng, Ralph A. Schmid and Thomas M. Marti
    Citation: Cancer Cell International 2019 19:317
    Content type: Primary research Published on:

  35. Glioma is a lethal malignant brain tumor, which affects the brain functions and is life-threatening. LncRNA UCA1 was identified as a pivotal regulator for tumorigenesis of glioma. MiR-206 was discovered to pro...

    Authors: Zhi Huang, Xuya Zhao, Xiaowen Wu, Lei Xiang, Yingnan Yuan, Shi Zhou and Wenfeng Yu
    Citation: Cancer Cell International 2019 19:316
    Content type: Primary research Published on:

  36. The prognostic value of pre-treatment platelet-to-lymphocyte ratio (PLR) in patients with urothelial carcinoma (UC) remains controversial. Therefore, this meta-analysis aimed to identify the prognostic impact ...

    Authors: Yuhai Bao, Yin Wang, Xiaodong Li, Mingjun Pan, Hongze Zhang, Zegen Cheng and Xueyi Wang
    Citation: Cancer Cell International 2019 19:315
    Content type: Primary research Published on:

  37. The plant homeodomain (PHD) finger protein 14 (PHF14) is a vital member of PHD finger protein families. Abnormal expression of PHF14 has been identified in various cancers and is known to be implicated in the ...

    Authors: Shuai Wu, Chen Luo, Fengjiao Li, N. U. Farrukh Hameed, Qiuyan Jin and Jie Zhang
    Citation: Cancer Cell International 2019 19:314
    Content type: Primary research Published on:

  38. Long noncoding RNAs (lncRNAs) play essential roles in tumor progression. However, the functions and targets of lncRNAs in neuroblastoma (NB) progression still remain to be determined. In this study, we aimed t...

    Authors: Huan-yu Zhang, Mao-qing Xing, Jing Guo, Jin-chuan Zhao, Xin Chen, Zhong Jiang, Hong Zhang and Qian Dong
    Citation: Cancer Cell International 2019 19:313
    Content type: Primary research Published on:

  39. Bladder cancer is the most common human urological malignancies with poor prognosis, and the pathophysiology of bladder cancer involves multi-linkages of regulatory networks in the bladder cancer cells. Recent...

    Authors: Jinan Guo, Zhixin Chen, Hongtao Jiang, Zhou Yu, Junming Peng, Jing Xie, ZaiShang Li, Weiqing Wu, Zhiqiang Cheng and Kefeng Xiao
    Citation: Cancer Cell International 2019 19:312
    Content type: Primary research Published on:

  40. Clear cell renal cell carcinoma (ccRCC) is the most common renal cell carcinoma subtype with a poor prognosis. LncRNA-LET is a long non-coding RNA (lncRNA) that is down-regulated in ccRCC tissues. However, its...

    Authors: Zhuo Ye, Jiachen Duan, Lihui Wang, Yanli Ji and Baoping Qiao
    Citation: Cancer Cell International 2019 19:311
    Content type: Primary research Published on:

  41. Amphicrine carcinoma, in which endocrine and epithelial cell constituents are present within the same cell, is very rare. This study characterized the clinicopathologic and survival analysis of this tumor, fur...

    Authors: Dan Huang, Fei Ren, Shujuan Ni, Cong Tan, Weiwei Weng, Meng Zhang, Midie Xu, Lei Wang, Qinghua Xu and Weiqi Sheng
    Citation: Cancer Cell International 2019 19:310
    Content type: Primary research Published on:

  42. Galectins constitute a family of β-galactoside-binding proteins, which influence various hallmarks of pancreatic cancer, including cell proliferation, invasion and migration; immune escape; and angiogenesis. A...

    Authors: Qiqing Sun, Yiyin Zhang, Mengqi Liu, Zeng Ye, Xianjun Yu, Xiaowu Xu and Yi Qin
    Citation: Cancer Cell International 2019 19:309
    Content type: Review Published on:

  43. MicroRNAs (miRNAs) play key roles in tumorigenesis and progression of gastric cancer (GC). miR-1269 has been reported to be upregulated in several cancers and plays a crucial role in carcinogenesis and cancer ...

    Authors: Wen-Li Liu, Hu-xia Wang, Cheng-xin Shi, Fei-yu Shi, Ling-yu Zhao, Wei Zhao and Guang-hui Wang
    Citation: Cancer Cell International 2019 19:308
    Content type: Primary research Published on:

  44. Lymph node metastasis is one of the most important factors affecting the prognosis of tongue cancer, and the molecular mechanism regulating lymph node metastasis of tongue cancer is poorly known.

    Authors: Fang Xiao, Yinhua Dai, Yujiao Hu, Mengmeng Lu and Qun Dai
    Citation: Cancer Cell International 2019 19:307
    Content type: Primary research Published on:

  45. Increased cell mobility is a signature when tumor cells undergo epithelial-to-mesenchymal transition. TGF-β is a key stimulating factor to promote the transcription of a variety of downstream genes to accelera...

    Authors: Jing Huang, Siyuan Chang, Yabin Lu, Jing Wang, Yang Si, Lijian Zhang, Shan Cheng and Wen G. Jiang
    Citation: Cancer Cell International 2019 19:306
    Content type: Primary research Published on:

  46. Switch-associated protein 70 (SWAP-70) is a guanine nucleotide exchange factor that is involved in cytoskeletal rearrangement and regulation of migration and invasion of malignant tumors. However, the mechanis...

    Authors: Lin Shi, Huize Liu, Yifeng Wang, Yulong Chong, Jie Wang, Guanzheng Liu, Xu Zhang, Xiangyu Chen, Huan Li, Mingshan Niu, Jun Liang, Rutong Yu and Xuejiao Liu
    Citation: Cancer Cell International 2019 19:305
    Content type: Primary research Published on:

  47. Cervical cancer (CC) is the fourth leading cause of cancer-associated death in women worldwide. Recently, long noncoding RNA (lncRNA) prostate cancer gene expression marker 1 (PCGEM1) has been demonstrated to ...

    Authors: Qian Zhang, Jindan Zheng and Lili Liu
    Citation: Cancer Cell International 2019 19:304
    Content type: Primary research Published on:

  48. Ovarian cancer is the third most common cause of death among gynecologic malignancies worldwide. Understanding the biology and molecular pathogenesis of ovarian epithelial tumors is key to developing improved ...

    Authors: Amata Amy Soriano, Tiziana de Cristofaro, Tina Di Palma, Serena Dotolo, Priyanka Gokulnath, Antonella Izzo, Gaetano Calì, Angelo Facchiano and Mariastella Zannini
    Citation: Cancer Cell International 2019 19:303
    Content type: Primary research Published on:

  49. Tongue squamous cell carcinoma (TSCC) is a most invasive cancer with high mortality and poor prognosis. It is reported that lncRNA DANCR has implications in multiple types of cancers. However, its biological r...

    Authors: Ying Zheng, Bowen Zheng, Xue Meng, Yuwen Yan, Jia He and Yi Liu
    Citation: Cancer Cell International 2019 19:302
    Content type: Primary research Published on:
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Cancer Cell International

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