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  1. The incidence of lung squamous cell carcinoma (LUSC) increased substantially in recent years. Systematical investigation of the immunogenomic pattern is critical to improve the prognosis of LUSC.

    Authors: Jianguo Zhang, Jianzhong Zhang, Cheng Yuan, Yuan Luo, Yangyi Li, Panpan Dai, Wenjie Sun, Nannan Zhang, Jiangbo Ren, Junhong Zhang, Yan Gong and Conghua Xie
    Citation: Cancer Cell International 2020 20:330
    Content type: Primary research Published on:

  2. Despite decades of therapeutic trials, effective diagnosis, many drugs available and numerous studies on breast cancer, it remains the deadliest cancer in women. In order to choose the most appropriate treatme...

    Authors: Augustin Le Naour, Yvonne Koffi, Mariane Diab, Delphine Le Guennec, Stéphanie Rougé, Sahar Aldekwer, Nicolas Goncalves-Mendes, Jérémie Talvas, Marie-Chantal Farges, Florence Caldefie-Chezet, Marie-Paule Vasson and Adrien Rossary
    Citation: Cancer Cell International 2020 20:328
    Content type: Primary research Published on:

  3. The outlook for new therapeutic approaches is pivotal to ameliorate the deterioration caused by the abrogated Wnt signaling. Long non-coding RNAs (lncRNAs) are tiny molecules that have begun emerging as vital mol...

    Authors: Zeeshan Javed, Khushbukhat Khan, Haleema Sadia, Shahid Raza, Bahare Salehi, Javad Sharifi-Rad and William C. Cho
    Citation: Cancer Cell International 2020 20:326
    Content type: Review Published on:

  4. Cholangiocarcinoma (CCA) is a mortal cancer with high mortality, whereas the function and mechanism of occurrence and progression of CCA are still mysterious. Long non-coding RNAs (lncRNAs) could function as i...

    Authors: Lining Huang, Xingming Jiang, Zhenglong Li, Jinglin Li, Xuan Lin, Zengtao Hu and Yunfu Cui
    Citation: Cancer Cell International 2020 20:324
    Content type: Primary research Published on:

  5. Prostate cancer (PCa) is a malignant heterogeneous tumor that threatens men’s health. Long non-coding RNA activated by DNA damage (NORAD) and microRNA-495-3p (miR-495-3p) have been revealed to be concerned wit...

    Authors: Fengling Chen, Ling Liu and Shuya Wang
    Citation: Cancer Cell International 2020 20:323
    Content type: Primary research Published on:

  6. Long non-coding RNAs (lncRNAs) have been defined as vital regulators in the progression of human cancers, including colorectal cancer (CRC). Long intergenic non-protein coding RNA 667 (LINC00667) is a tumor pr...

    Authors: Juan Yu, Furang Wang, Jun Zhang, Jing Li, Xiaoguang Chen and Guangsen Han
    Citation: Cancer Cell International 2020 20:322
    Content type: Primary research Published on:

  7. Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) play vital roles in human cancers. Nevertheless, the effects of lncRNAs and miRNAs on breast cancer (BC) remain to be further investigated. This study was d...

    Authors: Shaoqiang Cheng, Bingshu Xia, Hongbin Li, Yuying Li, Xinxin Lv, Yue Zhang and Yuanxi Huang
    Citation: Cancer Cell International 2020 20:321
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2021 21:104

  8. Breast cancer (BC) is a common malignancy worldwide. It has been reported that long non-coding RNA (lncRNA) HOX transcript antisense RNA (HOTAIR) is abnormally expressed in BC. However, the role of HOTAIR in t...

    Authors: Yuanyuan Wang, Guoliang Gong, Jingyun Xu, Yuanxin Zhang, Shenggui Wu and Shaohong Wang
    Citation: Cancer Cell International 2020 20:320
    Content type: Primary research Published on:

  9. Long noncoding RNA (lncRNA) is generally identified as competing endogenous RNA (ceRNA) that plays a vital role in the pathogenesis of kidney renal clear cell carcinoma (KIRC), the most common subtype of renal...

    Authors: Di Zhang, Song Zeng and Xiaopeng Hu
    Citation: Cancer Cell International 2020 20:319
    Content type: Primary research Published on:

  10. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Yang Hu, Hong Xie, Yankun Liu, Weiying Liu, Min Liu and Hua Tang
    Citation: Cancer Cell International 2020 20:318
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2017 17:36

  11. Papillary renal cell carcinoma (pRCC) accounting for near 20% of renal cell carcinoma is the second most common histological subtype. MiRNAs have been demonstrated to played significant roles on predicting pro...

    Authors: Ge Li, Haifan Yang, Yong Cheng, Xin Zhao, Xu Li and Rui Jiang
    Citation: Cancer Cell International 2020 20:317
    Content type: Primary research Published on:

  12. Cell cycle dysregulation plays a key role in the pathogenesis of malignant tumors. As a part of the CDK-activating kinase (CAK) trimeric complex, cyclin H is necessary to regulate the cell cycle and proliferat...

    Authors: Chen Peng, Yansong Yang, Li Ji, Panpan Yang, Xiaoqing Yang and Yuquan Zhang
    Citation: Cancer Cell International 2020 20:316
    Content type: Primary research Published on:

  13. Accumulating amount of evidence has highlighted the important roles of long non-coding RNAs (lncRNAs) acting as competing endogenous RNAs (ceRNAs) in tumor pathogenesis. However, the roles of long non coding R...

    Authors: Zhichen Kang, Lixin Guo, Zhuo Zhu and Rongfeng Qu
    Citation: Cancer Cell International 2020 20:315
    Content type: Primary research Published on:

  14. Although the medical level is constantly improving, cancer is still a major disease that threatens human health, and very effective treatments have not been found. In recent years, studies have found that four...

    Authors: Yaoyue Qi, Hui Li, Jing Lv, Weiwei Qi, Liwei Shen, Shihai Liu, Aiping Ding, Gongjun Wang, Libin Sun and Wensheng Qiu
    Citation: Cancer Cell International 2020 20:314
    Content type: Primary research Published on:

  15. The aim of this study was to investigate the association between telomerase reverse transcriptase (TERT) gene polymorphisms and acute myeloid leukemia (AML) susceptibility in a Chinese Han population.

    Authors: Yong Tong, Yinzhou Xiang, Bao Li, Shijie Bao, Ying Zhou, Wen Yuan, Yu Ling, Dan Hao, Huamin Zhu and Zhiqiang Sun
    Citation: Cancer Cell International 2020 20:313
    Content type: Primary research Published on:

  16. Prostate cancer (PCa) is the second cause of cancer related death in North American men. Androgens play an important role in its progression by regulating the expression of several genes including fusion ones ...

    Authors: Carlos D. Cruz-Hernández, Marian Cruz-Burgos, Sergio A. Cortés-Ramírez, Alberto Losada-García, Ignacio Camacho-Arroyo, Patricia García-López, Elizabeth Langley, Vanessa González-Covarrubias, Monserrat Llaguno-Munive, Martha E. Albino-Sánchez, José L. Cruz-Colín, Carlos Pérez-Plasencia, Fredy O. Beltrán-Anaya and Mauricio Rodríguez-Dorantes
    Citation: Cancer Cell International 2020 20:312
    Content type: Primary research Published on:

  17. Long noncoding ribonucleic acid (lncRNA) promoter methylation is closely related to the occurrence and development of hepatocellular carcinoma (HCC). Thus, we aim to screen and verify the lncRNA promoter methy...

    Authors: Zhuo Lin, Xiaofeng Ni, Shengjie Dai, Hao Chen, Jianhui Chen, Boda Wu, Jianyang Ao, Keqing Shi and Hongwei Sun
    Citation: Cancer Cell International 2020 20:311
    Content type: Primary research Published on:

  18. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults with a poor prognosis. DEPDC1B (DEP domain-containing protein 1B) has been shown to be associated with some types of malignancies. ...

    Authors: Xu Chen, Zheng-Qian Guo, Dan Cao, Yong Chen and Jian Chen
    Citation: Cancer Cell International 2020 20:310
    Content type: Primary research Published on:

  19. Ovarian serous cystadenocarcinoma (OSC) is the most common and lethal gynecological cancer in women worldwide; however, biomarkers to diagnose and predict prognosis of OSC remain limited. Therefore, the presen...

    Authors: Wei Huang, Yongjian Zhang, Ye Xu, Shaoyou Yang, Bing Li, Lan Huang and Ge Lou
    Citation: Cancer Cell International 2020 20:309
    Content type: Primary research Published on:

  20. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Rustelle Janse van Vuuren, Mandie Botes, Tamarin Jurgens, Anna Margaretha Joubert and Iman van den Bout
    Citation: Cancer Cell International 2020 20:308
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2019 19:1

  21. Although the fact that long non-coding RNA MCM3AP antisense RNA 1 (MCM3AP-AS1) is oncogenic in several cancers is well documented, very few researchers investigate its expression and function in prostate cancer.

    Authors: Jie Wu, Yalin Lv, Yujun Li, Yanxia Jiang, Lili Wang, Xiangyan Zhang, Mengqi Sun, Yuwei Zou, Jin Xu and Li Zhang
    Citation: Cancer Cell International 2020 20:307
    Content type: Primary research Published on:

  22. Autophagy is associated with cancer development. Autophagy-related genes play significant roles in endometrial cancer (EC), a major gynecological malignancy worldwide, but little was known about their value as...

    Authors: Hui Wang, Xiaoling Ma, Jinhui Liu, Yicong Wan, Yi Jiang, Yankai Xia and Wenjun Cheng
    Citation: Cancer Cell International 2020 20:306
    Content type: Primary research Published on:

  23. Osteosarcoma (OS) is the most common bone malignant tumor in children, youth, and adolescents. Circular RNA hsa_circ_0005909 (circ_0005909) is involved in the progression of OS. Nevertheless, there are few rep...

    Authors: Shuai Ding, Guangquan Zhang, Yanzheng Gao, Shulian Chen and Chen Cao
    Citation: Cancer Cell International 2020 20:305
    Content type: Primary research Published on:

  24. It has been widely reported that the expression levels of SNHG20 are elevated in diverse types of cancers, indicating that SNHG20 may participate in cancer initiation and development. Besides, accumulating evi...

    Authors: Hanlong Zhu, Si Zhao, Ruonan Jiao, Huishan Wang, Ruiyi Tang, Xiaochao Wu, Fei Wang, Xianxiu Ge, Quanpeng Li and Lin Miao
    Citation: Cancer Cell International 2020 20:304
    Content type: Review Published on:

  25. Gastric cancer (GC) is the leading cause of death worldwide and is closely related to metastasis. MRTF-A is one of the most well-characterized genetic markers in cancer. However, the mechanism whereby MRTF-A m...

    Authors: Libin Yin, Tao Liu, Chenyao Li, Guoqiang Yan, Chao Li, Jiantao Zhang and Lei Wang
    Citation: Cancer Cell International 2020 20:303
    Content type: Primary research Published on:

  26. Bladder cancer (BCa) is one of the important tumors that have been proven to be treatable with immunotherapy. This study aims to identify and validate a molecular prognostic index of BCa based on immunogenomic...

    Authors: Ning Xu, Zhi-Bin Ke, Xiao-Dan Lin, Ye-Hui Chen, Yu-Peng Wu, Yu Chen, Ru-Nan Dong, Shao-Hao Chen, Xiao-Dong Li, Yong Wei, Qing-Shui Zheng, Yun-Zhi Lin and Xue-Yi Xue
    Citation: Cancer Cell International 2020 20:302
    Content type: Primary research Published on:

  27. Researches validate that circular RNAs (circRNAs) are dysregulated in a variety of malignancies and play an important role in regulating the malignant phenotype of tumor cells. Nevertheless, the role of circ_0...

    Authors: Li Zhang, Jie Wu, Yujun Li, Yanxia Jiang, Lili Wang, Yunqing Chen, Yalin Lv, Yuwei Zou and Xiaoyan Ding
    Citation: Cancer Cell International 2020 20:301
    Content type: Primary research Published on:

  28. The mechanisms of neuronal protein γ-synuclein (SNCG) in the malignancy of oral squamous cell carcinoma (OSCC) are not clear. This study tested the hypothesis that SNCG is involved in nicotine-induced malignan...

    Authors: Chia-Chen Hsu, Yu-Fu Su, Kuo-Yang Tsai, Feng-Chih Kuo, Chi-Fu Chiang, Chu-Yen Chien, Ying-Chen Chen, Chien-Hsing Lee, Yu-Chiao Wu, Kun Wang, Shyun-Yeu Liu and Yi-Shing Shieh
    Citation: Cancer Cell International 2020 20:300
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:410

  29. Small nucleolar RNAs (snoRNAs) are a new non-coding RNAs (ncRNAs), which have not been widely investigated and are identified to be involved in tumorigenesis. But the function of snoRNAs in BLCA has not been r...

    Authors: Rui Cao, Bo Ma, Lushun Yuan, Gang Wang and Ye Tian
    Citation: Cancer Cell International 2020 20:299
    Content type: Primary research Published on:

  30. Cancer remains one of the major culprits causing disease-related deaths and leads to a high morbidity and similar mortality. Insidious onset, difficult early detection and a lack of broad-spectrum and effectiv...

    Authors: Yizhi Wang, Li Zhou, Jun Lu, Bolun Jiang, Chengxi Liu and Junchao Guo
    Citation: Cancer Cell International 2020 20:298
    Content type: Review Published on:

  32. Pancreatic ductal adenocarcinoma (PDAC), a subtype of pancreatic cancer, is a malignant tumor with unfavorable prognosis. Despite accumulating researches have made efforts on finding novel therapeutic methods ...

    Authors: Liping Wu, Yongcun Liu, Cheng Guo and Yuan Shao
    Citation: Cancer Cell International 2020 20:296
    Content type: Primary research Published on:

  33. Hepatocellular carcinoma (HCC) is a common malignant tumor in China. Advanced treatment like transcatheter hepatic arterial chemoembolization (TACE) has prolonged the lives of man...

    Authors: Xialei Liu, Lewei Yang, Dong Jiang, Wuzhu Lu and Yongyu Zhang
    Citation: Cancer Cell International 2020 20:295
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2021 21:355

  34. Thyroid cancer (TC) is the most frequent endocrine malignancy. Long noncoding RNAs (lncRNAs) have been confirmed to act as significant roles in tumor development. The role of lncRNA TMPO-AS1 in TC is still unc...

    Authors: Zhenyu Li, Yun Feng, Zhen Zhang, Xiaozhong Cao and Xiubo Lu
    Citation: Cancer Cell International 2020 20:294
    Content type: Primary research Published on:

  36. In cervical cancer, most patients die of metastasis. The epithelial-to-mesenchymal transition (EMT) is a pivotal and intricate process that increases the metastatic potential of cervical cancer. C-phycocyanin ...

    Authors: Huanhuan Ji, Guoxiang Liu, Jingjing Han, Feng Zhu, Xiaolei Dong and Bing Li
    Citation: Cancer Cell International 2020 20:292
    Content type: Primary research Published on:

  38. Bladder cancer is having a gradually increasing incidence in China. Except for the traditional chemotherapy drugs, there are no emerging new drugs for almost 30 years in bladder cancer. New potential therapeut...

    Authors: Songtao Cheng, Tianchen Peng, Xiaolu Zhu, Fenfang Zhou, Gang Wang, Lingao Ju, Yu Xiao, Xuefeng Liu and Xinghuan Wang
    Citation: Cancer Cell International 2020 20:290
    Content type: Primary research Published on:

  39. Cisplatin (DDP) is the first-line chemotherapeutic drug for non-small cell lung cancer (NSCLC), and long-term DDP stimulation increased resistance of NSCLC cells to this drug by enriching cancer stem cells (CS...

    Authors: Yongsheng Zhao, Renyan Zheng, Jian Chen and Dong Ning
    Citation: Cancer Cell International 2020 20:289
    Content type: Primary research Published on:

  40. At the present time, colorectal cancer (CRC) is still known as a disease with a high mortality rate. Theranostics are flawless scenarios that link diagnosis with therapy, including precision medicine as a crit...

    Authors: Somayeh Vafaei, Raheleh Roudi, Zahra Madjd, Amir Reza Aref and Marzieh Ebrahimi
    Citation: Cancer Cell International 2020 20:288
    Content type: Review Published on:

  41. Although tremendous improvement has been seen in cancer diagnosis and treatment, its morbidity and mortality is still high due to lack of ideal biomarkers. An increasing number of studies have demonstrated tha...

    Authors: Haixiang Shen, Qiwang Mo, Xin Xu and Ben Liu
    Citation: Cancer Cell International 2020 20:286
    Content type: Review Published on:

  42. Survival outcomes are significantly different in stage II colorectal cancer (CRC) patients with diverse clinicopathological features. The objective of this study is to establish a credible prognostic nomogram ...

    Authors: Shaobo Mo, Zheng Zhou, Yaqi Li, Xiang Hu, Xiaoji Ma, Long Zhang, Sanjun Cai and Junjie Peng
    Citation: Cancer Cell International 2020 20:285
    Content type: Primary research Published on:

  43. Evidence suggests that altered DNA methylation plays a causative role in the occurrence, progression and prognosis of gastric cancer (GC). Thus, methylated-differentially expressed genes (MDEGs) could potentia...

    Authors: Yang Li, Rongrong Sun, Youwei Zhang, Yuan Yuan and Yufeng Miao
    Citation: Cancer Cell International 2020 20:284
    Content type: Primary research Published on:

  44. Prostate cancer (PCa) greatly threatens men’s lives, with high incidence and mortality. Recently, the research of long non-coding RNAs (lncRNAs) has made breakthroughs in the development of human cancers. This...

    Authors: Huijuan Wu, Xin Tian and Chaoyang Zhu
    Citation: Cancer Cell International 2020 20:283
    Content type: Primary research Published on:

  45. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Wanqing Weng, Zhongjing Zhang, Weiguo Huang, Xiangxiang Xu, Boda Wu, Tingbo Ye, Yunfeng Shan, Keqing Shi and Zhuo Lin
    Citation: Cancer Cell International 2020 20:282
    Content type: Correction Published on:

    The original article was published in Cancer Cell International 2020 20:231

  46. Metastasis is a major cause of failed colorectal cancer (CRC) treatment. While lung metastasis (LM) is observed in 10–15% of patients with CRC, the genetic mechanisms that cause CRC to metastasize to the lung ...

    Authors: Nan Zhang, Jiabo Di, Zaozao Wang, Pin Gao, Beihai Jiang and Xiangqian Su
    Citation: Cancer Cell International 2020 20:281
    Content type: Primary research Published on:

  47. Aberrant activity of cell cycle proteins is one of the key somatic events in non-small cell lung cancer (NSCLC) pathogenesis. In most NSCLC cases, the retinoblastoma protein tumor suppressor (RB) becomes inact...

    Authors: Lindsey R. Conroy, Pawel Lorkiewicz, Liqing He, Xinmin Yin, Xiang Zhang, Shesh N. Rai and Brian F. Clem
    Citation: Cancer Cell International 2020 20:280
    Content type: Primary research Published on:

  48. Alternative splicing (AS) may cause structural and functional variations in the protein to promote the proliferation of tumor cells. However, there is no comprehensive analysis of the clinical significance of ...

    Authors: Chuan Liu, Chuan Hu, Zhi Li, Jing Feng, Jiale Huang, Bowen Yang and Ti Wen
    Citation: Cancer Cell International 2020 20:279
    Content type: Primary research Published on:

  49. Oncolytic viruses have emerged as an alternative therapeutic modality for cancer as they can replicate specifically in tumour cells and induce toxic effects leading to apoptosis. Despite the great potentials a...

    Authors: Syed Umar Faruq Syed Najmuddin, Zahiah Mohamed Amin, Sheau Wei Tan, Swee Keong Yeap, Jeevanathan Kalyanasundram, Muhamad Alhapis Che Ani, Abhimanyu Veerakumarasivam, Soon Choy Chan, Suet Lin Chia, Khatijah Yusoff and Noorjahan Banu Alitheen
    Citation: Cancer Cell International 2020 20:278
    Content type: Primary research Published on:

  50. There have been attempts to develop novel anti-tumor drugs in cancer therapy. Although satisfying results have been observed at a consequence of application of chemotherapeutic agents, the cancer cells are cap...

    Authors: Milad Ashrafizadeh, Masoud Najafi, Reza Mohammadinejad, Tahereh Farkhondeh and Saeed Samarghandian
    Citation: Cancer Cell International 2020 20:277
    Content type: Review Published on:
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Cancer Cell International

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