Genis L, Galvez BG, Gonzalo P, Arroyo AG: MT1-MMP: universal or particular player in angiogenesis?. Cancer Metastasis Rev. 2006, 25 (1): 77-86. 10.1007/s10555-006-7891-z.
Article
PubMed
Google Scholar
Itoh Y, Nagase H: Matrix metalloproteinases in cancer. Essays Biochem. 2002, 38: 21-36.
Article
CAS
PubMed
Google Scholar
Zucker S, Pei D, Cao J, Lopez-Otin C: Membrane type-matrix metalloproteinases (MT-MMP). Curr Topics Dev Biol. 2003, 54: 1-74.
Article
CAS
Google Scholar
Sato H, Takino T, Okada Y, Cao J, Shinagawa A, Yamamoto E, Seiki M: A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature. 1994, 370 (6484): 61-65. 10.1038/370061a0.
Article
CAS
PubMed
Google Scholar
Stetler-Stevenson WG, Liotta LA, Kleiner DE: Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis. Faseb J. 1993, 7 (15): 1434-1441.
CAS
PubMed
Google Scholar
Sato H, Takino T, Miyamori H: Roles of membrane-type matrix metalloproteinase-1 in tumor invasion and metastasis. Cancer Sci. 2005, 96 (4): 212-217. 10.1111/j.1349-7006.2005.00039.x.
Article
CAS
PubMed
Google Scholar
Skobe M, Hawighorst T, Jackson DG, Prevo R, Janes L, Velasco P, Riccardi L, Alitalo K, Claffey K, Detmar M: Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis. Nat Med. 2001, 7 (2): 192-198. 10.1038/84643.
Article
CAS
PubMed
Google Scholar
Akagi K, Ikeda Y, Miyazaki M, Abe T, Kinoshita J, Maehara Y, Sugimachi K: Vascular endothelial growth factor-C (VEGF-C) expression in human colorectal cancer tissues. British J Cancer. 2000, 83 (7): 887-891. 10.1054/bjoc.2000.1396.
Article
CAS
Google Scholar
Hotary K, Li XY, Allen E, Stevens SL, Weiss SJ: A cancer cell metalloprotease triad regulates the basement membrane transmigration program. Genes Dev. 2006, 20 (19): 2673-2686. 10.1101/gad.1451806.
Article
PubMed Central
CAS
PubMed
Google Scholar
Gilles C, Polette M, Coraux C, Tournier JM, Meneguzzi G, Munaut C, Volders L, Rousselle P, Birembaut P, Foidart JM: Contribution of MT1-MMP and of human laminin-5 gamma2 chain degradation to mammary epithelial cell migration. J Cell Sci. 2001, 114 (Pt 16): 2967-2976.
PubMed Central
CAS
PubMed
Google Scholar
Xu J, Rodriguez D, Petitclerc E, Kim JJ, Hangai M, Moon YS, Davis GE, Brooks PC: Proteolytic exposure of a cryptic site within collagen type IV is required for angiogenesis and tumor growth in vivo. J Cell Biol. 2001, 154 (5): 1069-1079. 10.1083/jcb.200103111.
Article
PubMed Central
CAS
PubMed
Google Scholar
Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P: Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nat Cell Biol. 2007, 9 (8): 893-904. 10.1038/ncb1616.
Article
CAS
PubMed
Google Scholar
Kajita M, Itoh Y, Chiba T, Mori H, Okada A, Kinoh H, Seiki M: Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration. J Cell Biol. 2001, 153 (5): 893-904. 10.1083/jcb.153.5.893.
Article
PubMed Central
CAS
PubMed
Google Scholar
Suenaga N, Mori H, Itoh Y, Seiki M: CD44 binding through the hemopexin-like domain is critical for its shedding by membrane-type 1 matrix metalloproteinase. Oncogene. 2005, 24 (5): 859-868. 10.1038/sj.onc.1208258.
Article
CAS
PubMed
Google Scholar
Deryugina EI, Bourdon MA, Jungwirth K, Smith JW, Strongin AY: Functional activation of integrin alpha V beta 3 in tumor cells expressing membrane-type 1 matrix metalloproteinase. Int J Cancer. 2000, 86 (1): 15-23. 10.1002/(SICI)1097-0215(20000401)86:1<15::AID-IJC3>3.0.CO;2-B.
Article
CAS
PubMed
Google Scholar
Deryugina EI, Ratnikov BI, Postnova TI, Rozanov DV, Strongin AY: Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase. J Biol Chem. 2002, 277 (12): 9749-9756. 10.1074/jbc.M110269200.
Article
CAS
PubMed
Google Scholar
Sodek KL, Ringuette MJ, Brown TJ: MT1-MMP is the critical determinant of matrix degradation and invasion by ovarian cancer cells. British J Cancer. 2007, 97 (3): 358-367. 10.1038/sj.bjc.6603863.
Article
CAS
Google Scholar
Bonnomet A, Polette M, Strumane K, Gilles C, Dalstein V, Kileztky C, Berx G, van Roy F, Birembaut P, Nawrocki-Raby B: The E-cadherin-repressed hNanos1 gene induces tumor cell invasion by upregulating MT1-MMP expression. Oncogene. 2008, 27 (26): 3692-3699. 10.1038/sj.onc.1211035.
Article
CAS
PubMed
Google Scholar
Chernov AV, Sounni NE, Remacle AG, Strongin AY: Epigenetic control of the invasion-promoting MT1-MMP/MMP-2/TIMP-2 axis in cancer cells. J Biol Chem. 2009, 284 (19): 12727-12734. 10.1074/jbc.M900273200.
Article
PubMed Central
CAS
PubMed
Google Scholar
Achen MG, Stacker SA: Molecular control of lymphatic metastasis. Ann NY Acad Sci. 2008, 1131: 225-234. 10.1196/annals.1413.020.
Article
CAS
PubMed
Google Scholar
Su JL, Yang PC, Shih JY, Yang CY, Wei LH, Hsieh CY, Chou CH, Jeng YM, Wang MY, Chang KJ: The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer cell. 2006, 9 (3): 209-223. 10.1016/j.ccr.2006.02.018.
Article
CAS
PubMed
Google Scholar
Yu M, Tang Z, Alousi S, Berk RS, Miller F, Kosir MA: Expression patterns of lymphangiogenic and angiogenic factors in a model of breast ductal carcinoma in situ. Am J Surg. 2007, 194 (5): 594-599. 10.1016/j.amjsurg.2007.08.007.
Article
CAS
PubMed
Google Scholar
Bock JM, Sinclair LL, Bedford NS, Jackson RE, Lee JH, Trask DK: Modulation of cellular invasion by VEGF-C expression in squamous cell carcinoma of the head and neck. Arch Otolaryngolog Head Neck Surg. 2008, 134 (4): 355-362. 10.1001/archotol.134.4.355.
Article
Google Scholar
Donnem T, Al-Saad S, Al-Shibli K, Delghandi MP, Persson M, Nilsen MN, Busund LT, Bremnes RM: Inverse prognostic impact of angiogenic marker expression in tumor cells versus stromal cells in non small cell lung cancer. Clin Cancer Res. 2007, 13 (22 Pt 1): 6649-6657.
Article
CAS
PubMed
Google Scholar
Donnem T, Al-Shibli K, Al-Saad S, Busund LT, Bremnes RM: Prognostic impact of fibroblast growth factor 2 in non-small cell lung cancer: coexpression with VEGFR-3 and PDGF-B predicts poor survival. J Thorac Oncol. 2009, 4 (5): 578-585. 10.1097/JTO.0b013e31819f2e38.
Article
PubMed
Google Scholar
Simiantonaki N, Jayasinghe C, Michel-Schmidt R, Peters K, Hermanns MI, Kirkpatrick CJ: Hypoxia-induced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines. Int J Oncol. 2008, 32 (3): 585-592.
CAS
PubMed
Google Scholar
Witte D, Thomas A, Ali N, Carlson N, Younes M: Expression of the vascular endothelial growth factor receptor-3 (VEGFR-3) and its ligand VEGF-C in human colorectal adenocarcinoma. Anticancer Res. 2002, 22 (3): 1463-1466.
CAS
PubMed
Google Scholar
Simiantonaki N, Taxeidis M, Jayasinghe C, Kirkpatrick CJ: Epithelial expression of VEGF receptors in colorectal carcinomas and their relationship to metastatic status. Anticancer Res. 2007, 27 (5A): 3245-3250.
PubMed
Google Scholar
Neuchrist C, Erovic BM, Handisurya A, Fischer MB, Steiner GE, Hollemann D, Gedlicka C, Saaristo A, Burian M: Vascular endothelial growth factor C and vascular endothelial growth factor receptor 3 expression in squamous cell carcinomas of the head and neck. Head Neck. 2003, 25 (6): 464-474. 10.1002/hed.10235.
Article
PubMed
Google Scholar
Warburton G, Nikitakis NG, Roberson P, Marinos NJ, Wu T, Sauk JJ, Ord RA, Wahl SM: Histopathological and lymphangiogenic parameters in relation to lymph node metastasis in early stage oral squamous cell carcinoma. J Oral Maxillofac Surg. 2007, 65 (3): 475-484. 10.1016/j.joms.2005.12.074.
Article
PubMed
Google Scholar
Kaushal V, Mukunyadzi P, Dennis RA, Siegel ER, Johnson DE, Kohli M: Stage-specific characterization of the vascular endothelial growth factor axis in prostate cancer: expression of lymphangiogenic markers is associated with advanced-stage disease. Clin Cancer Res. 2005, 11 (2 Pt 1): 584-593.
CAS
PubMed
Google Scholar
Ma C, Lin H, Leonard SS, Shi X, Ye J, Luo J: Overexpression of ErbB2 enhances ethanol-stimulated intracellular signaling and invasion of human mammary epithelial and breast cancer cells in vitro. Oncogene. 2003, 22 (34): 5281-5290. 10.1038/sj.onc.1206675.
Article
CAS
PubMed
Google Scholar
Steeg PS: Metastasis suppressors alter the signal transduction of cancer cells. Nature Rev. 2003, 3 (1): 55-63. 10.1038/nrc967.
CAS
Google Scholar
Kim HJ, Park CI, Park BW, Lee HD, Jung WH: Expression of MT-1 MMP, MMP2, MMP9 and TIMP2 mRNAs in ductal carcinoma in situ and invasive ductal carcinoma of the breast. Yonsei Med J. 2006, 47 (3): 333-342. 10.3349/ymj.2006.47.3.333.
Article
PubMed Central
CAS
PubMed
Google Scholar
Tetu B, Brisson J, Wang CS, Lapointe H, Beaudry G, Blanchette C, Trudel D: The influence of MMP-14, TIMP-2 and MMP-2 expression on breast cancer prognosis. Breast Cancer Res. 2006, 8 (3): R28-10.1186/bcr1503.
Article
PubMed Central
PubMed
Google Scholar
Ogura S, Ohdaira T, Hozumi Y, Omoto Y, Nagai H: Metastasis-related factors expressed in pT1 pN0 breast cancer: assessment of recurrence risk. J Surg Oncol. 2007, 96 (1): 46-53. 10.1002/jso.20805.
Article
CAS
PubMed
Google Scholar
Jiang WG, Davies G, Martin TA, Parr C, Watkins G, Mason MD, Mansel RE: Expression of membrane type-1 matrix metalloproteinase, MT1-MMP in human breast cancer and its impact on invasiveness of breast cancer cells. Int J Mol Med. 2006, 17 (4): 583-590.
PubMed
Google Scholar
Jones JL, Glynn P, Walker RA: Expression of MMP-2 and MMP-9, their inhibitors, and the activator MT1-MMP in primary breast carcinomas. J Pathol. 1999, 189 (2): 161-168. 10.1002/(SICI)1096-9896(199910)189:2<161::AID-PATH406>3.0.CO;2-2.
Article
CAS
PubMed
Google Scholar
Mylona E, Nomikos A, Magkou C, Kamberou M, Papassideri I, Keramopoulos A, Nakopoulou L: The clinicopathological and prognostic significance of membrane type 1 matrix metalloproteinase (MT1-MMP) and MMP-9 according to their localization in invasive breast carcinoma. Histopathology. 2007, 50 (3): 338-347. 10.1111/j.1365-2559.2007.02615.x.
Article
CAS
PubMed
Google Scholar
Ishigaki S, Toi M, Ueno T, Matsumoto H, Muta M, Koike M, Seiki M: Significance of membrane type 1 matrix metalloproteinase expression in breast cancer. Jpn J Cancer Res. 1999, 90 (5): 516-522. 10.1111/j.1349-7006.1999.tb00778.x.
Article
CAS
PubMed
Google Scholar
Teramoto S, Arihiro K, Koseki M, Kataoka T, Asahara T, Ohdan H: Role of vascular endothelial growth factor-C and -D mRNA in breast cancer. Hiroshima J Med Sci. 2008, 57 (2): 73-78.
CAS
PubMed
Google Scholar
Nakamura Y, Yasuoka H, Tsujimoto M, Yang Q, Tsukiyama A, Imabun S, Nakahara M, Nakao K, Nakamura M, Mori I: Clinicopathological significance of vascular endothelial growth factor-C in breast carcinoma with long-term follow-up. Mod Pathol. 2003, 16 (4): 309-314. 10.1097/01.MP.0000062858.98295.9F.
Article
PubMed
Google Scholar
Kurebayashi J, Otsuki T, Kunisue H, Mikami Y, Tanaka K, Yamamoto S, Sonoo H: Expression of vascular endothelial growth factor (VEGF) family members in breast cancer. Jpn J Cancer Res. 1999, 90 (9): 977-981. 10.1111/j.1349-7006.1999.tb00844.x.
Article
CAS
PubMed
Google Scholar
Li YS, Kaneko M, Amatya VJ, Takeshima Y, Arihiro K, Inai K: Expression of vascular endothelial growth factor-C and its receptor in invasive micropapillary carcinoma of the breast. Pathol Int. 2006, 56 (5): 256-261. 10.1111/j.1440-1827.2006.01961.x.
Article
CAS
PubMed
Google Scholar
Mohammed RA, Green A, El-Shikh S, Paish EC, Ellis IO, Martin SG: Prognostic significance of vascular endothelial cell growth factors -A, -C and -D in breast cancer and their relationship with angio- and lymphangiogenesis. British J Cancer. 2007, 96 (7): 1092-1100. 10.1038/sj.bjc.6603678.
Article
CAS
Google Scholar
Kinoshita J, Kitamura K, Kabashima A, Saeki H, Tanaka S, Sugimachi K: Clinical significance of vascular endothelial growth factor-C (VEGF-C) in breast cancer. Breast Cancer Res Treat. 2001, 66 (2): 159-164. 10.1023/A:1010692132669.
Article
CAS
PubMed
Google Scholar
Bando H, Weich HA, Horiguchi S, Funata N, Ogawa T, Toi M: The association between vascular endothelial growth factor-C, its corresponding receptor, VEGFR-3, and prognosis in primary breast cancer: a study with 193 cases. Oncol Rep. 2006, 15 (3): 653-659.
CAS
PubMed
Google Scholar
Nakamura Y, Yasuoka H, Tsujimoto M, Yoshidome K, Nakahara M, Nakao K, Nakamura M, Kakudo K: Nitric oxide in breast cancer: induction of vascular endothelial growth factor-C and correlation with metastasis and poor prognosis. Clin Cancer Res. 2006, 12 (4): 1201-1207. 10.1158/1078-0432.CCR-05-1269.
Article
CAS
PubMed
Google Scholar
Zhang XH, Huang DP, Guo GL, Chen GR, Zhang HX, Wan L, Chen SY: Coexpression of VEGF-C and COX-2 and its association with lymphangiogenesis in human breast cancer. BMC cancer. 2008, 8: 4-10.1186/1471-2407-8-4.
Article
PubMed Central
PubMed
Google Scholar
Watanabe O, Kinoshita J, Shimizu T, Imamura H, Hirano A, Okabe T, Aiba M, Ogawa K: Expression of a CD44 variant and VEGF-C and the implications for lymphatic metastasis and long-term prognosis of human breast cancer. J Exp Clin Cancer Res. 2005, 24 (1): 75-82.
CAS
PubMed
Google Scholar
Schoppmann SF, Fenzl A, Nagy K, Unger S, Bayer G, Geleff S, Gnant M, Horvat R, Jakesz R, Birner P: VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival. Surgery. 2006, 139 (6): 839-846. 10.1016/j.surg.2005.12.008.
Article
PubMed
Google Scholar
Gisterek I, Matkowski R, Kozlak J, Dus D, Lacko A, Szelachowska J, Kornafel J: Evaluation of prognostic value of VEGF-C and VEGF-D in breast cancer–10 year’s follow-up analysis. Anticancer Res. 2007, 27 (4C): 2797-2802.
CAS
PubMed
Google Scholar
van der Schaft DW, Pauwels P, Hulsmans S, Zimmermann M, van de Poll-Franse LV, Griffioen AW: Absence of lymphangiogenesis in ductal breast cancer at the primary tumor site. Cancer letters. 2007, 254 (1): 128-136. 10.1016/j.canlet.2007.03.001.
Article
CAS
PubMed
Google Scholar
Muller A, Homey B, Soto H, Ge N, Catron D, Buchanan ME, McClanahan T, Murphy E, Yuan W, Wagner SN: Involvement of chemokine receptors in breast cancer metastasis. Nature. 2001, 410 (6824): 50-56. 10.1038/35065016.
Article
CAS
PubMed
Google Scholar
Kriehuber E, Breiteneder-Geleff S, Groeger M, Soleiman A, Schoppmann SF, Stingl G, Kerjaschki D, Maurer D: Isolation and characterization of dermal lymphatic and blood endothelial cells reveal stable and functionally specialized cell lineages. J Exp Med. 2001, 194 (6): 797-808. 10.1084/jem.194.6.797.
Article
PubMed Central
CAS
PubMed
Google Scholar
Alitalo K, Tammela T, Petrova TV: Lymphangiogenesis in development and human disease. Nature. 2005, 438 (7070): 946-953. 10.1038/nature04480.
Article
CAS
PubMed
Google Scholar
Boardman KC, Swartz MA: Interstitial flow as a guide for lymphangiogenesis. Circulation Res. 2003, 92 (7): 801-808. 10.1161/01.RES.0000065621.69843.49.
Article
CAS
PubMed
Google Scholar
Bauer SM, Bauer RJ, Liu ZJ, Chen H, Goldstein L, Velazquez OC: Vascular endothelial growth factor-C promotes vasculogenesis, angiogenesis, and collagen constriction in three-dimensional collagen gels. J Vasc Surg. 2005, 41 (4): 699-707. 10.1016/j.jvs.2005.01.015.
Article
PubMed
Google Scholar
Nakamura ES, Koizumi K, Kobayashi M, Saiki I: Inhibition of lymphangiogenesis-related properties of murine lymphatic endothelial cells and lymph node metastasis of lung cancer by the matrix metalloproteinase inhibitor MMI270. Cancer science. 2004, 95 (1): 25-31. 10.1111/j.1349-7006.2004.tb03166.x.
Article
CAS
PubMed
Google Scholar
Choi WW, Lewis MM, Lawson D, Yin-Goen Q, Birdsong GG, Cotsonis GA, Cohen C, Young AN: Angiogenic and lymphangiogenic microvessel density in breast carcinoma: correlation with clinicopathologic parameters and VEGF-family gene expression. Mod Pathol. 2005, 18 (1): 143-152. 10.1038/modpathol.3800253.
Article
CAS
PubMed
Google Scholar
Kahn HJ, Marks A: A new monoclonal antibody, D2-40, for detection of lymphatic invasion in primary tumors. Lab Invest. 2002, 82 (9): 1255-1257. 10.1097/01.LAB.0000028824.03032.AB.
Article
PubMed
Google Scholar
Weidner N: Current pathologic methods for measuring intratumoral microvessel density within breast carcinoma and other solid tumors. Breast Cancer Res Treat. 1995, 36 (2): 169-180. 10.1007/BF00666038.
Article
CAS
PubMed
Google Scholar