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  1. Tumors display a high rate of glucose metabolism and the SLC2A (also known as GLUT) gene family may be central regulators of cellular glucose uptake. However, roles of SLC2A family in mechanism of metabolite c...

    Authors: Xingxing Yao, Zhanke He, Caolitao Qin, Xiangqian Deng, Lan Bai, Guoxin Li and Jiaolong Shi
    Citation: Cancer Cell International 2020 20:503
    Content type: Primary research Published on:

  2. Triple-negative breast cancer (TNBC) is a highly aggressive malignancy that lacks sensitivity to chemotherapy, endocrine therapy or targeted therapy. CDK4/6 inhibitors, combined with endocrine therapy, have be...

    Authors: Yajing Huang, Hao Wu and Xingrui Li
    Citation: Cancer Cell International 2020 20:501
    Content type: Primary research Published on:

  3. Cervical cancer is the second leading cause of death in women 20–39 years old. Because coverage for cervical cancer screening is low, and the vaccination rate of human papillomavirus (HPV) is poor in some coun...

    Authors: Chang Yang, Zhao-Cong Zhang, Tian -Bo Liu, Ye Xu, Bai-Rong Xia and Ge Lou
    Citation: Cancer Cell International 2020 20:500
    Content type: Primary research Published on:

  4. Accumulating evidence has emerged revealing that noncoding RNAs (ncRNAs) play essential roles in the occurrence and development of hepatocellular carcinoma (HCC). However, the complicated regulatory interactio...

    Authors: Gang Xu, Wei-Yu Xu, Yao Xiao, Bao Jin, Shun-Da Du, Yi-lei Mao and Zhong-Tao Zhang
    Citation: Cancer Cell International 2020 20:496
    Content type: Review Published on:

  5. Colorectal cancer (CRC) is one of the most common cancers worldwide. Circular RNAs (circRNAs), a novel class of non-coding RNAs, have been confirmed to be key regulators of many diseases. With many scholars de...

    Authors: Yahang Liang, Jingbo Shi, Qingsi He, Guorui Sun, Lei Gao, Jianhong Ye, Xiaolong Tang and Hui Qu
    Citation: Cancer Cell International 2020 20:494
    Content type: Primary research Published on:

  6. Pancreatic cancer (PC) is one of the most common cancers and the leading cause of cancer-related death worldwide. Exploring novel predictive biomarkers for PC patients’ prognosis is in urgent need.

    Authors: Hongkai Zhuang, Shanzhou Huang, Zixuan Zhou, Zuyi Ma, Zedan Zhang, Chuanzhao Zhang and Baohua Hou
    Citation: Cancer Cell International 2020 20:493
    Content type: Primary research Published on:

  7. The NF1 gene encodes neurofibromin, which is one of the primary negative regulatory factors of the Ras protein. Neurofibromin stimulates the GTPase activity of Ras to convert it from an active GTP-bound form to i...

    Authors: Junyan Tao, Dantong Sun, Lina Dong, Hua Zhu and Helei Hou
    Citation: Cancer Cell International 2020 20:492
    Content type: Review Published on:

  8. MiR-924 has been reported to be a tumor suppressor in hepatocellular carcinoma. However, the functions and mechanisms of miR-924 in non-small cell lung cancer (NSCLC) remain unclear.

    Authors: Huaishi Wang, Xi Chen, Baishuang Yang, Zhi Xia and Qiong Chen
    Citation: Cancer Cell International 2020 20:491
    Content type: Primary research Published on:

  9. Glioblastoma multiforme (GBM) is the most malignant tumor in human brain, with highly heterogeneity among different patients. Age could function as an incidence and prognosis risk factor for many tumors.

    Authors: Hongwang Song, Xiaojun Fu, Chenxing Wu and Shouwei Li
    Citation: Cancer Cell International 2020 20:489
    Content type: Primary research Published on:

    The Retraction Note to this article has been published in Cancer Cell International 2021 21:201

  10. Endometrial carcinoma (EC) is one of the three major malignant tumors of the female reproductive system. In recent years, the incidence and mortality rate of EC have increased. B-cell translocation gene 1 (BTG...

    Authors: Yibing Li, Jianing Huo, Junjian He, Yunzheng Zhang and Xiaoxin Ma
    Citation: Cancer Cell International 2020 20:490
    Content type: Primary research Published on:

  11. Cancers may be treated by selective targeting of the genes vital for their survival. A number of attempts have led to discovery of several genes essential for surviving of tumor cells of different types. In th...

    Authors: Irina A. Krivosheeva, Alexandra Yu. Filatova, Sergei A. Moshkovskii, Ancha V. Baranova and Mikhail Yu. Skoblov
    Citation: Cancer Cell International 2020 20:488
    Content type: Primary research Published on:

  12. Interleukin-35 (IL-35) has been reported to play an important role in the progression of cancers. The role of IL-35 in prostate cancer (PCA) is not well understood. In this study, we investigated the effects o...

    Authors: Jialin Zhu, Yan Wang, Dai Li, Haonan Zhang, Zhi Guo and Xueling Yang
    Citation: Cancer Cell International 2020 20:487
    Content type: Primary research Published on:

  13. This article has been retracted. Please see the retraction notice for more detail: https://doi.org/10.1186/s12935-020-01574-4.

    Authors: Xiaonian Zhu, Wei Luo, Chunhua Bei, Juan Kong, Shidong Zhang, Yuanyuan Fu, Di Li and Shengkui Tan
    Citation: Cancer Cell International 2020 20:486
    Content type: Retraction Note Published on:

    The original article was published in Cancer Cell International 2019 19:340

  14. This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12935-020-01586-0.

    Authors: Yu Fu, Limin Cai, Xuexue Lei and Dunwei Wang
    Citation: Cancer Cell International 2020 20:485
    Content type: Retraction Note Published on:

    The original article was published in Cancer Cell International 2019 19:338

  15. Recently, it has been demonstrated that circular RNA (circRNA) contributes to the production and progression in human cancer. However, the specific function and underlying mechanism of circ_0028171 in osteosar...

    Authors: Feng Pan, Jun Zhang, Benseng Tang, Li Jing, Bing Qiu and Zhengang Zha
    Citation: Cancer Cell International 2020 20:484
    Content type: Primary research Published on:

  16. Glucose 6-phosphate dehydrogenase (G6PD) serves key roles in cancer cell metabolic reprogramming, and has been reported to be involved in certain carcinogenesis. Previous results from our laboratory demonstrat...

    Authors: Qiao Zhang, Zhe Yang, Yueli Ni, Honggang Bai, Qiaoqiao Han, Zihan Yi, Xiaojia Yi, Yannick Luther Agbana, Yingmin Kuang and Yuechun Zhu
    Citation: Cancer Cell International 2020 20:483
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:565

  17. We aim to explore association between copy number alteration (CNA) and sensitivity to common tyrosine kinase inhibitors (TKIs) used in clear-cell renal cell carcinoma (ccRCC) treatment.

    Authors: Liang Wang, Yuqing Li, Yinfeng Lyu, Hui Wen and Chenchen Feng
    Citation: Cancer Cell International 2020 20:482
    Content type: Primary research Published on:

  18. Circular RNAs (circRNAs) are important regulators in the pathogenesis of diseases and affects the occurrence and development of diseases. However, the role of circRNAs in osteosarcoma (OS) has not been fully e...

    Authors: Zhisheng Long, Feipeng Gong, Yuxu Li, Zhiqiang Fan and Jingtang Li
    Citation: Cancer Cell International 2020 20:481
    Content type: Primary research Published on:

  19. Chemoresistance reduces the 5-year survival rate of endometrial cancer patient, which is the current major obstacle for cancer therapy. Increasing evidence state that Nrf2 contributes to chemoresistance in sev...

    Authors: Hong Liao, Dan Zhu, Mingzhu Bai, Huifen Chen, Shihuan Yan, Jing Yu, Huiting Zhu, Wenxin Zheng and Guorong Fan
    Citation: Cancer Cell International 2020 20:480
    Content type: Primary research Published on:

  21. Luminal subtype is the most common subgroup of breast cancer (BC), accounting for more than 70% of this cancer. Long non-coding RNAs (lncRNAs) are a group of RNAs which play critical roles in diverse cellular ...

    Authors: Sepideh Mehrpour Layeghi, Maedeh Arabpour, Rezvan Esmaeili, Mohammad Mehdi Naghizadeh, Javad Tavakkoly Bazzaz and Abbas Shakoori
    Citation: Cancer Cell International 2020 20:478
    Content type: Primary research Published on:

  22. Exploring novel and sensitive targets is urgent due to the high morbidity of endometrial cancer (EC). The purpose of our study was to explore the transcription factors and immune-related genes in EC and furthe...

    Authors: Yiru Wang, Yunduo Liu, Yue Guan, Hao Li, Yuan Liu, Mengjun Zhang, Ping Cui, Dan Kong, Xiuwei Chen and Hang Yin
    Citation: Cancer Cell International 2020 20:477
    Content type: Primary research Published on:

  23. Compelling evidences reported the role of microRNAs (miRNAs) in ovarian cancer. However, little was known regarding the molecular mechanism of miR-367 in ovarian cancer. This study intended to investigate the ...

    Authors: Qingling Zheng, Xin Dai, Wei Fang, Yan Zheng, Jin Zhang, Yanxiang Liu and Donghua Gu
    Citation: Cancer Cell International 2020 20:476
    Content type: Primary research Published on:

  24. Colorectal cancer ranks among the most lethal diseases worldwide. Although much progress has been made in research and treatment of colorectal cancer in recent years, the underlying mechanisms related to migra...

    Authors: Weifeng Xu, Beibei Chen, Dianshan Ke and Xiaobing Chen
    Citation: Cancer Cell International 2020 20:475
    Content type: Primary research Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:533

  26. Colorectal cancer (CRC) is one of the most general malignant tumors. Accumulating evidence implied that long non-coding RNA Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) participated in the t...

    Authors: Changru Fan, Qiulan Yuan, Guifeng Liu, Yuliang Zhang, Maojun Yan, Qingxu Sun and Chaoyu Zhu
    Citation: Cancer Cell International 2020 20:473
    Content type: Primary research Published on:

  27. Recurrence remains a major obstacle to long-term survival of laryngeal squamous cell carcinoma (LSCC). We conducted a genome-wide integrated analysis of methylation and the transcriptome to establish methylati...

    Authors: Jie Cui, Liping Wang, Waisheng Zhong, Zhen Chen, Jie Chen, Hong Yang and Genglong Liu
    Citation: Cancer Cell International 2020 20:472
    Content type: Primary research Published on:

  29. Dysfunction of microRNAs (miRNAs) is a major cause of aberrant expression of inflammatory cytokines and contributes to macrophage polarization. Proinflammatory M1 macrophages promote T helper (Th) 1 responses ...

    Authors: Jiping Rong, Lu Xu, Yinying Hu, Fan Liu, Yanrong Yu, Hongyan Guo, Xudong Ni, Yanqin Huang, Lin Zhao and Zhigang Wang
    Citation: Cancer Cell International 2020 20:470
    Content type: Primary research Published on:

  30. MicroRNAs (miRNAs) are important regulators for cancer cell proliferation. miR-585 has been shown to inhibit the proliferation of several types of cancer, however, little is known about its role in human gliom...

    Authors: Wangsheng Chen, Lan Hong, Changlong Hou, Yibin Wang, Fei Wang and Jianhua Zhang
    Citation: Cancer Cell International 2020 20:469
    Content type: Primary research Published on:

  31. Increasing evidence has shown that the transcription factor SOX4 is closely associated with the development and progression of many malignant tumors. However, the effect of SOX4 on breast cancer is unclear. In...

    Authors: Jing Zhang, Chunhua Xiao, Zhenbo Feng, Yun Gong, Baohua Sun, Zhongqi Li, Yimin Lu, Xiaojie Fei, Weizhu Wu, Xiaoping Sun and Lisong Teng
    Citation: Cancer Cell International 2020 20:468
    Content type: Primary research Published on:

  32. In recent years, the B cell receptor (BCR) signaling pathway has become a “hot point” because it plays a critical role in B-cell proliferation and function. Bruton’s tyrosine kinase (BTK) is overexpressed in m...

    Authors: Chao Xue, Xin Wang, Lingyan Zhang, Qingyuan Qu, Qian Zhang and Yujie Jiang
    Citation: Cancer Cell International 2020 20:467
    Content type: Review Published on:

  34. Mounting evidence implicates circular RNAs (circRNAs) in various biological processes during cancer progression. Gastric cancer is a main cause of cancer-related deaths worldwide. Herein, we aimed at investiga...

    Authors: Nan Zhou, Hui Qiao, Miaomiao Zeng, Lei Yang, Yongning Zhou and Quanlin Guan
    Citation: Cancer Cell International 2020 20:465
    Content type: Primary research Published on:

  35. N6-methyladenosine (m6A) modification might be closely associated with the genesis and development of gastric cancer (GC). Currently, the evidence established by high-throughput assay for GC-related m6A patterns ...

    Authors: Zhi Lv, Liping Sun, Qian Xu, Chengzhong Xing and Yuan Yuan
    Citation: Cancer Cell International 2020 20:464
    Content type: Primary research Published on:

  36. Emerging studies have disclosed long non-coding RNAs (lncRNAs) as pivotal modulators in the progression of prostate cancer (PCa). Current research planned to figure out the involvement of lncRNA nicotinamide n...

    Authors: Changlei Yao, Xianghua Cheng, Xiuquan Guo, Xulou Lu, Fan Bu and Yanfen Xu
    Citation: Cancer Cell International 2020 20:463
    Content type: Primary research Published on:

  37. Several studies were conducted to explore the prognostic value of modified Glasgow Prognostic Score (mGPS) in pancreatic cancer, which reported contradictory results. The purpose of this meta-analysis was to s...

    Authors: Huan Zhang, Dianyun Ren, Xin Jin and Heshui Wu
    Citation: Cancer Cell International 2020 20:462
    Content type: Primary research Published on:

  38. Large-scale initiatives like The Cancer Genome Atlas (TCGA) performed genomics studies on predominantly Caucasian kidney cancer. In this study, we aimed to investigate genomics of Chinese clear cell renal cell...

    Authors: Qiang Zhao, Jia Xue, Baoan Hong, Wubin Qian, Tiezhu Liu, Bin Fan, Jie Cai, Yongpeng Ji, Jia Liu, Yong Yang, Qixiang Li, Sheng Guo and Ning Zhang
    Citation: Cancer Cell International 2020 20:461
    Content type: Primary research Published on:

  39. LncRNAs act as functional regulators in tumor progression through interacting with various signaling pathways in multiple types of cancer. However, the effect of LINC02418 on colorectal cancer (CRC) progressio...

    Authors: Jun Tian, Peng Cui, Yifei Li, Xuequan Yao, Xiaoyu Wu, Zhirong Wang and Chunsheng Li
    Citation: Cancer Cell International 2020 20:460
    Content type: Primary research Published on:

  40. Centromere protein F (CENPF) is a key component of the kinetochore complex involved in mitosis, cell differentiation and cellular response to stresses. However, the alteration of CENPF in response to endoplasm...

    Authors: Tao Shen, Yan Li, Shuang Liang and Zhiguang Chen
    Citation: Cancer Cell International 2020 20:459
    Content type: Primary research Published on:

  41. Radiotherapy is one of the main treatments for pancreatic cancer, but radiation resistance limits its clinical application. As a result, novel therapeutic agents to improve radiosensitivity are urgently needed...

    Authors: Biqin Tan, Rong Dong, Bo Zhang, Youyou Yan, Qingyu Li, Fei Wang and Nengming Lin
    Citation: Cancer Cell International 2020 20:458
    Content type: Primary research Published on:

  42. Pancreatic cancer is one of the main causes of tumor-related deaths worldwide because of its low morbidity but extremely high mortality, and is therefore colloquially known as the “king of cancer.” Sudden onse...

    Authors: Yizhi Wang, Li Zhou, Jun Lu, Bolun Jiang, Chengxi Liu, Junchao Guo and Gary Guishan Xiao
    Citation: Cancer Cell International 2020 20:457
    Content type: Review Published on:

  43. Cancer immunotherapy has been emerged as a promising strategy for treatment of a broad spectrum of malignancies ranging from hematological to solid tumors. One of the principal approaches of cancer immunothera...

    Authors: Seyed Mohammad Miri, Elham Tafsiri, William Chi Shing Cho and Amir Ghaemi
    Citation: Cancer Cell International 2020 20:456
    Content type: Review Published on:

    The Correction to this article has been published in Cancer Cell International 2020 20:521

  44. Some studies have investigated the prognostic value exhibited by the Prognostic Nutritional Index (PNI) in patients suffering diffuse large B-cell lymphoma (DLBCL), but varying results were obtained. In order ...

    Authors: Chunyan Luan, Fei Wang, Ning Wei and Baoan Chen
    Citation: Cancer Cell International 2020 20:455
    Content type: Research Article Published on:

  45. Triple-negative breast cancer (TNBC) is a clinically aggressive subtype of breast cancer with a bad prognosis. Chemotherapy is still the standard of care for TNBC treatment. Circular RNAs (CircRNAs) have been ...

    Authors: Dongwei Dou, Xiaoyang Ren, Mingli Han, Xiaodong Xu, Xin Ge, Yuanting Gu, Xinxing Wang and Song Zhao
    Citation: Cancer Cell International 2020 20:454
    Content type: Primary research Published on:

  46. It has been well documented that long non-coding RNAs (lncRNAs) regulate numerous characteristics of cancer, including proliferation, migration, metastasis, apoptosis, and even metabolism. LncRNA BCYRN1 (BCYRN...

    Authors: Liu Yang, Yinan Zhang, Jun Bao and Ji-Feng Feng
    Citation: Cancer Cell International 2020 20:453
    Content type: Primary research Published on:

  47. Drug resistance to 5-fluorouracil (5-FU) and recurrence after chemotherapy in colorectal cancer remain a challenge to be resolved for the improvement of patient outcomes. It is recognized that a variety of sec...

    Authors: Siyuan Chang, Jing Huang, Huan Niu, Jing Wang, Yang Si, Zhigang Bai, Shan Cheng and Wei Ding
    Citation: Cancer Cell International 2020 20:452
    Content type: Primary research Published on:

  48. Kejinyan decoction, as an experienced formula of Zhou Zhongying (the Master of Traditional Chinese Medicine) has been widely used in clinic for lung cancer treatment in China, while the anti-lung cancer mechan...

    Authors: Meijuan Chen, Cheng Hu, Qian Gao, Liqiu Li, Ziyu Cheng, Qirui Li, Zhihui Li, Zhaohui Wang, Zejia Mao, Weiqian Tian and Xu Zhang
    Citation: Cancer Cell International 2020 20:451
    Content type: Primary research Published on:

  49. Hexokinase domain component 1 (HKDC1) plays an oncogenic role in certain types of cancer, such as lymphoma, liver cancer, and breast cancer. Previous bioinformatics study revealed that HKDC1 was significantly ...

    Authors: Xinyu Wang, Bowen Shi, Yue Zhao, Qijue Lu, Xiang Fei, Chaojing Lu, Chunguang Li and Hezhong Chen
    Citation: Cancer Cell International 2020 20:450
    Content type: Primary research Published on:

  50. To analyze the clinical efficacy of intraoperative radiotherapy (IORT) after breast-conserving surgery (BCS) in patients with early-stage breast cancer (BC), and to investigate the relationship between its inf...

    Authors: Lin Wang, Minmin Zhu, Yuelong Cui, Xudong Zhang and Guowen Li
    Citation: Cancer Cell International 2020 20:446
    Content type: Primary research Published on:
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Cancer Cell International

ISSN: 1475-2867

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