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  1. Oral squamous cell carcinoma (OSCC) is a prevalent neoplasm worldwide, necessitating a deeper understanding of its pathogenesis. VGF nerve growth factor inducible (VGF), a neuropeptide, plays critical roles in...

    Authors: Chung-Hsien Chou, Chun-Han Yen, Chung-Ji Liu, Hsi-Feng Tu, Shu-Chun Lin and Kuo-Wei Chang
    Citation: Cancer Cell International 2024 24:115
  2. Gastric cancer (GC) remains a malignant tumor with high morbidity and mortality, accounting for approximately 1,080,000 diagnosed cases and 770,000 deaths worldwide annually. Disulfidptosis, characterized by t...

    Authors: Jie Li, Tian Yu, Juan Sun, Mingwei Ma, Zicheng Zheng, Yixuan He, Weiming Kang and Xin Ye
    Citation: Cancer Cell International 2024 24:112
  3. Gastric cancer is currently estimated to be the fifth leading common cancer in the world, and responsible for about one million new cases and an estimated 769,000 cancer-related deaths each year. WFDC21P is lo...

    Authors: Jinyao Dong, Yongqiang Lv, Debin Meng, Ruyi Shi, Feng Li, Rui Guo, Yi Wang, Jiansheng Guo and Yanyan Zhang
    Citation: Cancer Cell International 2024 24:111
  4. Resistance to targeted therapies represents a significant hurdle to successfully treating hepatocellular carcinoma (HCC). While epigenetic abnormalities are critical determinants of HCC relapse and therapeutic...

    Authors: Tao Cheng, Changli Zhou, Sicheng Bian, Kelsey Sobeck and Yahui Liu
    Citation: Cancer Cell International 2024 24:110
  5. Noninvasive biomarkers for the assessment of response to chemotherapy in advanced breast cancer (BCa) are essential for optimized therapeutic decision-making. We evaluated the potential of soluble Periostin (P...

    Authors: Li Jia, Wenwei Hu, Xu Yan, Jie Shao, Yuhong Guo, Aimin Zhang, Lianzi Yu, Yunli Zhou, Yueguo Li, Li Ren and Dong Dong
    Citation: Cancer Cell International 2024 24:109
  6. Conventional cancer treatments can cause serious side effects because they are not specific to cancer cells and can damage healthy cells. Aptamers often are single-stranded oligonucleotides arranged in a uniqu...

    Authors: Fatemeh Mahmoudian, Azin Ahmari, Shiva Shabani, Bahman Sadeghi, Shohreh Fahimirad and Fahimeh Fattahi
    Citation: Cancer Cell International 2024 24:108
  7. A higher number of tumor buds in the invasive front of colorectal cancer (CRC) specimens has been shown to contribute to a poor prognosis in CRC patients. Because macrophages (Mφs) have been demonstrated to al...

    Authors: Ichiro Kawamura, Rintaro Ohe, Kazushi Suzuki, Takanobu Kabasawa, Takumi Kitaoka, Daiichiro Takahara, Michihisa Kono, Naoya Uchiyama, Hiroaki Musha, Mitsuru Futakuchi and Fuyuhiko Motoi
    Citation: Cancer Cell International 2024 24:107
  8. Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy and the most frequently acute leukemia of stem cell precursors and the myeloid derivatives in adult. Longitudinal studies have indi...

    Authors: Leisheng Zhang, Yunyan Sun, Chun-e Xue, Shuling Wang, Xianghong Xu, Chengyun Zheng, Cunrong Chen and Dexiao Kong
    Citation: Cancer Cell International 2024 24:106
  9. Immune microenvironment and immunotherapy have become the focus and frontier of tumor research, and the immune checkpoint inhibitors has provided novel strategies for tumor treatment. Malignant pleural effusio...

    Authors: Shan Ge, Yuwei Zhao, Jun Liang, Zhongning He, Kai Li, Guanghui Zhang, Baojin Hua, Honggang Zheng, Qiujun Guo, Runzhi Qi and Zhan Shi
    Citation: Cancer Cell International 2024 24:105
  10. Breast cancer is significantly influenced by endoplasmic reticulum (ER) stress, impacting both its initiation and progression. When cells experience an accumulation of misfolded or unfolded proteins, they acti...

    Authors: Negin Karamali, Arshia Daraei, Arman Rostamlou, Roya Mahdavi, Zahra Akbari Jonoush, Nooshin Ghadiri, Zahra Mahmoudi, Amirhossein Mardi, Moslem Javidan, Sepideh Sohrabi and Behzad Baradaran
    Citation: Cancer Cell International 2024 24:104
  11. Colorectal cancer (CRC) is a malignancy of remarkable heterogeneity and heightened morbidity. Cancer associated fibroblasts (CAFs) are abundant in CRC tissues and are essential for CRC growth. Here, we aimed t...

    Authors: Zizhen Zhang, Shengde Liu, Zhenghang Wang, Shuo Wang, Lei Jiang, Xicheng Wang, Jian Li and Lin Shen
    Citation: Cancer Cell International 2024 24:103
  12. Despite advances in therapeutic strategies, resistance to immunotherapy and the off-target effects of targeted therapy have significantly weakened the benefits for patients with melanoma.

    Authors: Wanxian Chen, Deyi Geng, Jiasheng Chen, Xiaosha Han, Qihu Xie, Genghong Guo, Xuefen Chen, Wancong Zhang, Shijie Tang and Xiaoping Zhong
    Citation: Cancer Cell International 2024 24:101
  13. Allogeneic tumors are eradicated by host immunity; however, it is unknown how it is initiated until the report in Nature by Yaron Carmi et al. in 2015. Currently, we know that allogeneic tumors are eradicated by ...

    Authors: Ying Liu, Yuanyi Huang, Hong-Wei Cui, YingYing Wang, ZhaoWu Ma, Ying Xiang, Hong-Yi Xin, Jun-Qing Liang and Hong-Wu Xin
    Citation: Cancer Cell International 2024 24:100
  14. Breast cancer is a major global health concern, and there is a continuous search for novel biomarkers to predict its prognosis. The mitochondrial protein NDUFAF6, previously studied in liver cancer, is now bei...

    Authors: Baohong Jiang, Sixuan Wu, Lijun Zeng, Yuanbin Tang, Lunqi Luo, Lianjie Ouyang, Wenjie Feng, Yeru Tan and Yuehua Li
    Citation: Cancer Cell International 2024 24:99
  15. Tumor organoids, especially patient-derived organoids (PDOs) exhibit marked similarities in histopathological morphology, genomic alterations, and specific marker expression profiles to those of primary tumour...

    Authors: Rong-Xuan Ning, Cun-Yu Liu, Shi-Qi Wang, Wen-Kai Li, Xia Kong and Zhi-Wei He
    Citation: Cancer Cell International 2024 24:98
  16. Gastrointestinal cancer, one of the most common cancers, continues to be a major cause of mortality and morbidity globally. Accumulating evidence has shown that alterations in mitochondrial energy metabolism a...

    Authors: Quanling Zhou, Xiaohui Li, Honglian Zhou, Juanjuan Zhao, Hailong Zhao, Lijuan Li and Ya Zhou
    Citation: Cancer Cell International 2024 24:97
  17. N6-methyladenosine (m6A) is dysregulated in various cancers, including colorectal cancer (CRC). Herein, we assess the diagnostic potential of peripheral blood (PB) m6A levels in CRC.

    Authors: Chunying Zhang, Jiadi Chen, Jingyi Ren, Xiaoyu Li, Yaqin Zhang, Bihan Huang, Yihan Xu, Luyan Dong and Yingping Cao
    Citation: Cancer Cell International 2024 24:96

    The Correction to this article has been published in Cancer Cell International 2024 24:126

  18. The present study aimed to investigate the expression level, biological function, and underlying mechanism of transmembrane protein 176B (TMEM176B) in gastric cancer (GC).

    Authors: Jing Li, ZiQing Fang, Emre Dal, Hao Zhang, KeXun Yu, MengDi Ma, MingLiang Wang, Ruochuan Sun, MingDian Lu, HuiZhen Wang and YongXiang Li
    Citation: Cancer Cell International 2024 24:95
  19. Recent investigations have reported the benefits of using a tyrosine kinase inhibitor, dasatinib (DA), as well as programmed death-ligand 1 (PD-L1) inhibitors in the management of several solid tumors, includi...

    Authors: Hadeel Kheraldine, Ishita Gupta, Farhan Sachal Cyprian, Semir Vranic, Halema F. Al-Farsi, Maysaloun Merhi, Said Dermime and Ala-Eddin Al Moustafa
    Citation: Cancer Cell International 2024 24:94
  20. Novel therapeutic targets are urgently needed for treating drug-resistant non-small cell lung cancer (NSCLC) and overcoming drug resistance to molecular-targeted therapies. Regulator of G protein signaling 20 ...

    Authors: Xiaoyan Ding, Xiaoxia Li, Yanxia Jiang, Yujun Li, Hong Li, Lipeng Shang, Guilin Feng, Huhu Zhang, Ziyuan Xu, Lina Yang, Bing Li and Robert Chunhua Zhao
    Citation: Cancer Cell International 2024 24:93
  21. Cholangiocarcinoma represents a malignant neoplasm originating from the hepatobiliary tree, with a subset of tumors developing inside the liver. Intrahepatic cholangiocarcinomas (ICC) commonly exhibit an asymp...

    Authors: Hefei Ren, Chang Liu, Cheng Zhang, Hongkun Wu, Jiafeng Zhang, Zhenhua Wang, Lei Chen, Huiquan Wang, Chenghao Shao and Lin Zhou
    Citation: Cancer Cell International 2024 24:92
  22. Circular RNAs (circRNAs) belong to a class of covalently closed single stranded RNAs that have been implicated in cancer progression. Former investigations showed that hsa-circ-0013561 is abnormally expressed ...

    Authors: Kaisai Tian, Liying Zheng, Tailei Yuan, Xiaoping Chen, Qun Chen, Xiaocheng Xue, Shuixian Huang, Weining He, Mingming Jin and Yi Zhang
    Citation: Cancer Cell International 2024 24:91
  23. Patients with colorectal cancer (CRC) with liver metastasis or drug resistance have a poor prognosis. Previous research has demonstrated that PPP2R1B inactivation results in the development of CRC. However, th...

    Authors: Wei Liu, Jingtong Tang, Wei Gao, Jian Sun, Gang Liu and Jianping Zhou
    Citation: Cancer Cell International 2024 24:90
  24. Cancer chemoresistance is a problematic dilemma that significantly restrains numerous cancer management protocols. It can promote cancer recurrence, spreading of cancer, and finally, mortality. Accordingly, en...

    Authors: Samar Sami Alkafaas, Mohamed I. Elsalahaty, Doha F. Ismail, Mustafa Ali Radwan, Sara Samy Elkafas, Samah A. Loutfy, Rami M. Elshazli, Narjes Baazaoui, Ahmed Ezzat Ahmed, Wael Hafez, Mohanad Diab, Mohamed Sakran, Mohamed T. El-Saadony, Khaled A. El-Tarabily, Hani K. Kamal and Mohamed Hessien
    Citation: Cancer Cell International 2024 24:89
  25. Many cancer-related deaths including melanoma result from metastases that develop months or years after the initial cancer therapy. Even the most effective drugs and immune therapies rarely eradicate all tumor...

    Authors: Kathrin Singvogel and Birgit Schittek
    Citation: Cancer Cell International 2024 24:88
  26. As a key enzyme in ceramide synthesis, longevity assurance homologue 2 (LASS2) has been indicated to act as a tumour suppressor in a variety of cancers. Ferroptosis is involved in a variety of tumour processes...

    Authors: Yunfei Huang, Jie Du, Dan Li, Wei He, Zhouheng Liu, Li Liu, Xiaoli Yang, Xiaoming Cheng, Rui Chen and Yan Yang
    Citation: Cancer Cell International 2024 24:87
  27. The role of Acyl-CoA dehydrogenase long chain (ACADL) in different tumor types had different inhibiting or promoting effect. However, its role in non-small cell lung cancer (NSCLC) carcinogenicity is not clear.

    Authors: Kegong Chen, Chunqiao Hong, Weibo Kong, Guanghua Li, Zhuang Liu, Kechao Zhu, Chen Lu, Panpan Si, Pan Gao, Guangyao Ning and Renquan Zhang
    Citation: Cancer Cell International 2024 24:86
  28. SLC25A17, a peroxisomal solute carrier, has been implicated in various physiological and pathological processes. However, its precise roles and underlying mechanisms in triple-negative breast cancer (TNBC) rem...

    Authors: Haiting Zhou, Jiahao Li, Yi He, Xiaohui Xia, Junxia Liu and Huihua Xiong
    Citation: Cancer Cell International 2024 24:85
  29. The incidence of multiple primary cancers (MPC), especially involving primary lung cancer (PLC) and primary hematologic malignancies (PHM), is rising. This study aims to analyze clinicopathological features, g...

    Authors: Mengchen Lyu, Lifeng Luo, Ling Zhou, Xiangran Feng, Jin Yang, Ziwei Xu, Xianwen Sun, Zhiyao Bao, Xiaofei Wang, Beili Gao and Yi Xiang
    Citation: Cancer Cell International 2024 24:84
  30. Apatinib was the first anti-angiogenic agent approved for treatment of metastatic gastric cancer (GC). However, the emergence of resistance was inevitable. Thus investigating new and valuable off-target effect...

    Authors: Bei Zhang, Yan Chen, Xinqi Chen, Zhiyao Ren, Hong Xiang, Lipeng Mao and Guodong Zhu
    Citation: Cancer Cell International 2024 24:83
  31. Acute myeloid leukemia (AML) is a malignancy of the hematopoietic system, and childhood AML accounts for about 20% of pediatric leukemia. ANP32B, an important nuclear protein associated with proliferation, has...

    Authors: Xiaomei Wan, Jianwei Wang, Fang Fang, Yixin Hu, Zimu Zhang, Yanfang Tao, Yongping Zhang, Juanjuan Yu, Yumeng Wu, Bi Zhou, Hongli Yin, Li Ma, Xiaolu Li, Ran Zhuo, Wei Cheng, Shuqi Zhang…
    Citation: Cancer Cell International 2024 24:81
  32. Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) still present a huge threaten to women’s health, especially the local advanced patients. Hence, developing more effectiveness prognostic ...

    Authors: Xiaomei Chen, Xunhu Dong, Hong Li, Tingting Wu, Haoyin Liu, Jie Wu, Wei Ge, Lingji Hao and Zhe Zhang
    Citation: Cancer Cell International 2024 24:80
  33. Hepatocellular carcinoma (HCC) cells usually show strong resistance to chemotherapy, which not only reduces the efficacy of chemotherapy but also increases the side effects. Regulation of autophagy plays an im...

    Authors: Lili Sun, Yaru Li, Renshuang Zhao, Qinlei Fan, Fei Liu, Yilong Zhu, Jicheng Han, Yunyun Liu, Ningyi Jin, Xiao Li and Yiquan Li
    Citation: Cancer Cell International 2024 24:79
  34. Liver specific genes (LSGs) are crucial for hepatocyte differentiation and maintaining normal liver function. A deep understanding of LSGs and their heterogeneity in hepatocellular carcinoma (HCC) is necessary...

    Authors: Xiuzhi Zhang, Zhefeng Xiao, Xia Zhang, Ningning Li, Tao Sun, JinZhong Zhang, Chunyan Kang, Shasha Fan, Liping Dai and Xiaoli liu
    Citation: Cancer Cell International 2024 24:78
  35. Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid peroxidation. Its role in cancer metastasis remains unclear. In this study, we aimed to investigate the potential involvement...

    Authors: Juan Sun, Jie Li, Kostas Pantopoulos, Yuqin Liu, Yixuan He, Weiming Kang and Xin Ye
    Citation: Cancer Cell International 2024 24:77
  36. To examine the role of RhoB expression in relation to chemotherapy response, clinical outcomes and associated signaling pathways in colorectal cancer patients.

    Authors: Maria Kopsida, Na Liu, Angeliki Kotti, Jing Wang, Lasse Jensen, Ganesan Jothimani, Camilla Hildesjo, Staffan Haapaniemi, Wen Zhong, Surajit Pathak and Xiao-Feng Sun
    Citation: Cancer Cell International 2024 24:75
  37. Breast cancer is the most prevalent female tumor, of which triple-negative breast cancer (TNBC) accounts for about 15%. Characterized by its aggressive nature and limited treatment options, TNBC currently stan...

    Authors: Mei Zhao, Panling Xu, Wenjing Shi, Juan Wang, Ting Wang and Ping Li
    Citation: Cancer Cell International 2024 24:74
  38. Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays an important role in diverse cellular processes by regulating Rho guanosine triphosphate (GTP)ases activity. RhoGDI1 phosphorylation regulates th...

    Authors: Jeewon Lim, Yo Sep Hwang, Hyang Ran Yoon, Jiyun Yoo, Suk Ran Yoon, Haiyoung Jung, Hee Jun Cho and Hee Gu Lee
    Citation: Cancer Cell International 2024 24:73
  39. Glioblastoma (GBM) is the most lethal primary brain tumor in adult, characterized by highly aggressive and infiltrative growth. The current therapeutic management of GBM includes surgical resection followed by...

    Authors: Giorgia Castellani, Mariachiara Buccarelli, Quintino Giorgio D’Alessandris, Ramona Ilari, Andrea Cappannini, Francesca Pedini, Alessandra Boe, Valentina Lulli, Isabella Parolini, Stefano Giannetti, Mauro Biffoni, Vincenzo Zappavigna, Giovanna Marziali, Roberto Pallini and Lucia Ricci-Vitiani
    Citation: Cancer Cell International 2024 24:72
  40. Gastric cancer (GC) stands as a prevalent and deadly global malignancy. Despite its role as a preoperative neoadjuvant therapy, Apatinib’s effectiveness is curtailed among GC patients exhibiting elevated YY1 e...

    Authors: Zi-Han Geng, Jun-Xian Du, Yue-Da Chen, Pei-Yao Fu, Ping-Hong Zhou, Wen-Zheng Qin and Yi-Hong Luo
    Citation: Cancer Cell International 2024 24:71
  41. Glioblastoma (GBM) is the most common brain tumor with the worst prognosis. Temozolomide is the only first-line drug for GBM. Unfortunately, the resistance issue is a classic problem. Therefore, it is essentia...

    Authors: Yizhi Zhang, Wan Li, Yihui Yang, Sen Zhang, Hong Yang, Yue Hao, Xu Fang, Guanhua Du, Jianyou Shi, Lianqiu Wu and Jinhua Wang
    Citation: Cancer Cell International 2024 24:69
  42. Cuproptosis-related genes (CRGs) are associated with lung adenocarcinoma. However, the links between CRGs and non-small-cell lung cancer (NSCLC) are not clear. In this study, we aimed to develop two cuproptosi...

    Authors: Yijie Tang, Tianyi Wang, Qixuan Li and Jiahai Shi
    Citation: Cancer Cell International 2024 24:68
  43. Targeted drug delivery is one of the attractive ways in which cancer treatment can significantly reduce side effects. In the last two decades, the use of antibodies as a tool for accurate detection of cancer h...

    Authors: Mohadeseh Haji Abdolvahab, Pegah Karimi, Nasrin Mohajeri, Mohammad Abedini and Hamed Zare
    Citation: Cancer Cell International 2024 24:67
  44. Acute myeloid leukemia (AML) is a malignant hematologic disease caused by gene mutations and genomic rearrangements in hematologic progenitors. The PHF6 (PHD finger protein 6) gene is highly conserved and loca...

    Authors: Shengnan Yuan, Mingming Gao, Yizhou Wang, Yanjie Lan, Mengrou Li, Yuwei Du, Yue Li, Wen Ju, Yujin Huang, Ke Yuan and Lingyu Zeng
    Citation: Cancer Cell International 2024 24:66
  45. Pediatric T-cell acute lymphoblastic leukemia (T-ALL) poses significant challenges due to its aggressive nature and resistance to standard treatments. Long non-coding RNAs (lncRNAs) have emerged as potential b...

    Authors: Pankaj Sharma, Parminder kaur, Prateek Bhatia, Amita Trehan, Sreejesh Sreedharanunni and Minu Singh
    Citation: Cancer Cell International 2024 24:65
  46. Esophageal cancer (EC) is a global canker notorious for causing high mortality due to its relentless incidence rate, convoluted with unyielding recurrence and metastasis. However, these intricacies of EC are a...

    Authors: Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang…
    Citation: Cancer Cell International 2024 24:64

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