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  1. Glycolysis is critical for harvesting abundant energy to maintain the tumor microenvironment in malignant tumors. Retinoic acid-related orphan receptor α (RORα) has been identified as a circadian gene. However...

    Authors: Xiaoshan Wang, Junyi Zhang, Yuwei Wu, Yuqing Zhang, Siyuan Zhang, Angqing Li, Jian Wang and Zhengguang Wang
    Citation: Cancer Cell International 2024 24:12
  2. In the Modern era, immune checkpoint inhibitors (ICIs) have been the cornerstone of success in the treatment of several malignancies. Despite remarkable therapeutic advances, complex matrix together with signi...

    Authors: Maryam Noori, Farideh Jafari-Raddani, Zeinab Davoodi-Moghaddam, Mahda Delshad, Saeid Safiri and Davood Bashash
    Citation: Cancer Cell International 2024 24:10
  3. Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer, with a high mortality rate and poor prognosis. Mutated or dysregulated transcription factors (TFs) are significantly associated with c...

    Authors: Meixia Wang, Hanyao Guo, Bo Zhang, Yanan Shang, Sidi Zhang, Xiaoyu Liu, Pengxiu Cao, Yumei Fan and Ke Tan
    Citation: Cancer Cell International 2024 24:9
  4. Despite advancements in treating metastatic melanoma, many patients exhibit resistance to targeted therapies. Our study focuses on ATP1A1, a sodium pump subunit associated with cancer development. We aimed to ...

    Authors: Laura Soumoy, Aline Genbauffe, Lena Mouchart, Alexandra Sperone, Anne Trelcat, Léa Mukeba-Harchies, Mathilde Wells, Bertrand Blankert, Ahmad Najem, Ghanem Ghanem, Sven Saussez and Fabrice Journe
    Citation: Cancer Cell International 2024 24:8
  5. The high invasiveness and infiltrative nature of Glioblastoma (GBM) pose significant challenges for surgical removal. This study aimed to investigate the role of KCNA1 in GBM progression.

    Authors: Weichao Wang, Yang Zhang, Xuetao Li, Qinzi E, Zuoyu Jiang, Qikun Shi, Yu Huang, Jian Wang and Yulun Huang
    Citation: Cancer Cell International 2024 24:7
  6. The tumor microenvironment and cancer-associated fibroblasts (CAFs) play crucial roles in tumor development, and their metabolic coupling remains unclear. Clinical data showed a positive correlation between PD...

    Authors: Jianguo Xu, Li Bian, Dingyun You, Ziliang Li, Tingting Wang, Yiting Li, Xiaobin Ren and Yongwen He
    Citation: Cancer Cell International 2024 24:5
  7. Cancer stem cells (CSCs) play a pivotal role in the pathogenesis of human cancers. Previous studies have highlighted the role of long non-coding RNA (lncRNA) in modulating the stemness of CSCs. In our investig...

    Authors: Liu Ouyang, Min-min Sun, Ping-sheng Zhou, Yi-wei Ren, Xin-yu Liu, Wan-ying Wei, Zhen-shun Song, Kai Lu and Li-xue Yang
    Citation: Cancer Cell International 2024 24:4
  8. The alterations of RNA profile in tumor-educated platelets (TEPs) have been described as a novel biosource for cancer diagnostics. This study aimed to explore the potential snoRNAs in TEP as biomarkers for dia...

    Authors: Xuan Zhao, Guanxuan Chen, Yawen Wu, Xiao Li, Zhe Zhang, Li Xie, Xianrang Song and Xingguo Song
    Citation: Cancer Cell International 2024 24:3
  9. Disulfidptosis is a recently proposed novel cell death mode in which cells with high SLC7A11 expression induce disulfide stress and cell death in response to glucose deficiency. The purpose of the research was to...

    Authors: Leqi Zhong, Wuguang Chang, Bin Luo, Wuyou Gao, Huanhuan He, Mouxiang Fang, Hongmu Li, Zhesheng Wen and Youfang Chen
    Citation: Cancer Cell International 2024 24:2
  10. Liver cancer is one of the most common cancers in the world and a primary cause of cancer-related death. In recent years, despite the great development of diagnostic methods and targeted therapies for liver ca...

    Authors: Qiaoping Xu, Ning Ren, Lanqi Ren, Yibei Yang, Junjie Pan and Hongkai Shang
    Citation: Cancer Cell International 2024 24:1
  11. Green tea, a popular and healthy nonalcoholic drink consumed globally, is abundant in natural polyphenols. One of these polyphenols is epigallocatechin-3-gallate (EGCG), which offers a range of health benefits...

    Authors: Guichun Wang, Jinyi Wang and Mohammad Reza Momeni
    Citation: Cancer Cell International 2023 23:335
  12. Circular RNAs (circRNAs) are a class of noncoding RNAs that are involved in the progression of many human cancers. The precise gene locus and the roles of circular RNA from Fibronectin type III domain containi...

    Authors: Congya Li, Linchao Ding, Xuyao Wang, Peng Shu, Xuchao Shi, Zhijian Zheng, Jian Liu and Junlan Zhu
    Citation: Cancer Cell International 2023 23:334
  13. DPY30 belongs to the core subunit of components of the histone lysine methyltransferase complex, which is implicated in tumorigenesis, cell senescence, and other biological events. However, its contribution to...

    Authors: Chun-Ying Luo, Wei-Chao Su, Hai-Feng Jiang, Ling-Tao Luo, Dong-Yan Shen and Guo-Qiang Su
    Citation: Cancer Cell International 2023 23:333
  14. Increasing evidence highlights the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors of renal cell carcinoma (RCC). Here, we explored the mechanism of AGAP2-AS1 in the occurrence and...

    Authors: Peng Xu, Da-xiong Feng, Jun Wang, Yao-Dong Wang, Gang Xie, Bin Zhang, Xiao-Han Li, Jia-Wei Zeng and Jia-Fu Feng
    Citation: Cancer Cell International 2023 23:330
  15. Cervical cancer is a leading cause of gynecological cancer death in the world. Human papillomavirus (HPV) is the most causative factor of cervical cancer. In addition, many genetic factors are involved in cerv...

    Authors: Li Li, Yixin Tong, Jianhong Wu and Xiangshang Xu
    Citation: Cancer Cell International 2023 23:329
  16. Chimeric antigen receptor (CAR) T-cells have revolutionized the treatment of CD19- and B-cell maturation antigen-positive haematological malignancies. However, the effect of a CAR construct on the function of ...

    Authors: Gerard J. Chu, Charles G. Bailey, Rajini Nagarajah, Sharon M. Sagnella, Stephen Adelstein and John E. J. Rasko
    Citation: Cancer Cell International 2023 23:327
  17. Fibroblasts, especially cancer-associated fibroblasts (CAFs), represent the predominant stromal cell population in the tumor microenvironment and have an important function in tumorigenesis by interacting with...

    Authors: Wei Cheng, Yonghui Liao, Yuan Xie, Qinrong Wang, Leilei Li, Yuanjia Chen, Yan Zhao and Jianjiang Zhou
    Citation: Cancer Cell International 2023 23:326
  18. Melanoma, a severe form of skin cancer, poses significant health risks due to its aggressive nature and potential for metastasis. The role of two-pore channel 2 (TPC2) in the development and progression of mel...

    Authors: Ali Hanbashi, Moureq Alotaibi, Homood M. As Sobeai, Lama Binobaid, Khalid Alhazzani, Xuhui Jin, Faroq Kamli, Ali Alhoshani and John Parrington
    Citation: Cancer Cell International 2023 23:325
  19. There has been a growing global interest in the potential health benefits of edible natural bioactive products in recent years. Ganoderma lucidum, a medicinal mushroom, has gained attention for its decadent array...

    Authors: Xiaoli Gao and Mina Homayoonfal
    Citation: Cancer Cell International 2023 23:324

    The Correction to this article has been published in Cancer Cell International 2024 24:178

  20. Breast cancer is the leading cause of cancer death for women worldwide. Most of the breast cancer death are due to disease recurrence and metastasis. Increasingly accumulating evidence indicates that mitochond...

    Authors: Yang Wang, Jieyi Wang, Lan Chen, Zhuo Chen, Tong Wang, Shuting Xiong, Tong Zhou, Guang Wu, Licai He, Jiawei Cao, Min Liu, Hongzhi Li and Haihua Gu
    Citation: Cancer Cell International 2023 23:323
  21. Lung cancer is the leading cause of cancer-related death. Lysosomes are key degradative compartments that maintain protein homeostasis. In current study, we aimed to construct a lysosomes-related genes signatu...

    Authors: Dingli Song, Lili Zhao, Guang Zhao, Qian Hao, Jie Wu, Hong Ren and Boxiang Zhang
    Citation: Cancer Cell International 2023 23:322
  22. Artificial intelligence (AI) is capable of integrating a large amount of related information to predict therapeutic relationships such as disease treatment with known drugs, gene expression, and drug-target bi...

    Authors: Na Ly Tran, Hyerim Kim, Cheol-Hee Shin, Eun Ko and Seung Ja Oh
    Citation: Cancer Cell International 2023 23:321
  23. Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide. Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional medicine against a variety of acute/...

    Authors: Farhad Sheikhnia, Vahid Rashidi, Hossein Maghsoudi and Maryam Majidinia
    Citation: Cancer Cell International 2023 23:320
  24. CD56 has been observed in malignant tumours exhibiting neuronal or neuroendocrine differentiation, such as breast cancer, small-cell lung cancer, and neuroblastoma. Abnormal glycosylation modifications are tho...

    Authors: Yuli Jian, Lin Zhang, Li Gong, Mengting Ding, Xiaoxin Sun, Xiao Yu, Shaohui Lv, Jinjing Li, Deyong Yang and Shujing Wang
    Citation: Cancer Cell International 2023 23:319
  25. Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year survival rate varies widely from 4 to 60%, mainly due t...

    Authors: Francisco Rodas, Jetzabel A. Vidal-Vidal, Daniela Herrera, David A. Brown-Brown, Diego Vera, Joaquín Veliz, Pilar Püschel, José I. Erices, Verónica Sánchez Hinojosa, Julio C. Tapia, Eduardo Silva-Pavez, Claudia Quezada-Monrás, Pablo Mendoza-Soto, Flavio Salazar-Onfray, Cristian Carrasco and Ignacio Niechi
    Citation: Cancer Cell International 2023 23:318
  26. Gastric cancer (GC) is the fifth most common malignancy and the third leading cause of cancer-related deaths worldwide. Similar to other types of tumors, GC cells undergo metabolic reprogramming and switch to ...

    Authors: Shanshan Zheng, Huaizhi Li, Yaqi Li, Xu Chen, Junyu Shen, Menglin Chen, Cancan Zhang, Jian Wu and Qingmin Sun
    Citation: Cancer Cell International 2023 23:317
  27. Gliomas, a prevalent form of primary brain tumors, are linked with a high mortality rate and unfavorable prognoses. Disulfidptosis, an innovative form of programmed cell death, has received scant attention con...

    Authors: Di Chen, Qiaoqiao Li, Yuan Xu, Yanfei Wei, Jianguo Li, Xuqiang Zhu, Hongjiang Li, Yan Lu, Xianzhi Liu and Dongming Yan
    Citation: Cancer Cell International 2023 23:316
  28. Type I interferons (IFNs) play a central role not only in innate immunity against viral infection, but also in the antitumour response, e.g. through a direct impact on cell proliferation. Particularly for canc...

    Authors: Felix Hiebinger, Aiste Kudulyte, Huanting Chi, Sebastian Burbano De Lara, Doroteja Ilic, Barbara Helm, Hendrik Welsch, Viet Loan Dao Thi, Ursula Klingmüller and Marco Binder
    Citation: Cancer Cell International 2023 23:315
  29. This study aims to compare the technical performance of Abbott’s UroVysion and Biocare’s CytoFISH urine cytology probe panel and position the CytoFISH probe panel as an alternative to UroVysion. The CytoFISH p...

    Authors: Tammy Anderson, Sharon Hartman, William Dunn, Harvey Bellin, Thomas W. Ehlers, Sarah Groen and Jason A. Ramos
    Citation: Cancer Cell International 2023 23:314
  30. Immune checkpoint blockade (ICB) has become a promising strategy in treating advanced cancers, providing significant survival benefits for patients with various cancer types. However, among the vast population...

    Authors: Boyu Sun, Ziyu Xun, Nan Zhang, Kai Liu, Xiangqi Chen and Haitao Zhao
    Citation: Cancer Cell International 2023 23:313
  31. The metastasis of melanoma cells to regional lymph nodes and distant sites is an important contributor to cancer-related morbidity and mortality among patients with melanoma. This intricate process entails dyn...

    Authors: Azadeh Rahimi, Zahra Malakoutikhah, Ilnaz Rahimmanesh, Gordon A. Ferns, Reza Nedaeinia, Sayed Mohammad Matin Ishaghi, Nasim Dana and Shaghayegh Haghjooy Javanmard
    Citation: Cancer Cell International 2023 23:312
  32. Histone chaperones (HCs) are crucial for governing genome stability and gene expression in multiple cancers. However, the functioning of HCs in the tumor microenvironment (TME) is still not clearly understood.

    Authors: Jindong Xie, Wei Deng, Xinpei Deng, Jie-Ying Liang, Yuhui Tang, Jun Huang, Hailin Tang, Yutian Zou, Huamao Zhou and Xiaoming Xie
    Citation: Cancer Cell International 2023 23:311
  33. This work compared the metabolic profile of a parental MDA-MB-231 cisplatin-sensitive triple negative breast cancer (TNBC) cell line with that of a derived cisplatin-resistant line, to characterize inherent me...

    Authors: Tatiana J. Carneiro, Ana L. M. Batista Carvalho, Martin Vojtek, Inês F. Carmo, Maria Paula M. Marques, Carmen Diniz and Ana M. Gil
    Citation: Cancer Cell International 2023 23:310
  34. Hepatocellular carcinoma (HCC) has a high incidence and mortality rate despite various treatment options, including 125I seed implantation. However, recurrence and radiation resistance remain challenging issues. ...

    Authors: Pan Hu, Letao Lin, Tao Huang, Zhenyu Li, Meigui Xiao, Huanqing Guo, Guanyu Chen, Dengyao Liu, Miaola Ke, Hongbo Shan, Fujun Zhang and Yanling Zhang
    Citation: Cancer Cell International 2023 23:308
  35. The HAND2-AS1 (HAND2 Antisense RNA 1) Long noncoding RNA (lncRNA) has emerged as a participant in the initiation of various cancer types, underscoring its pivotal involvement in both oncological processes and ...

    Authors: Pouria Samadi, Mina Shahnazari, Abolfazl Shekari, Fatemeh Maghool and Akram Jalali
    Citation: Cancer Cell International 2023 23:307
  36. Lymphocyte-activation gene 3 (LAG3) is a recently discovered immune checkpoint molecule that has been linked to immunosuppression and the advancement of cancer in different types of solid tumors. This study ai...

    Authors: Rongyang Li, Jianhao Qiu, Zhan Zhang, Chenghao Qu, Zhanpeng Tang, Wenhao Yu, Yu Tian and Hui Tian
    Citation: Cancer Cell International 2023 23:306
  37. High recurrence and metastasis rates and poor prognoses are the major challenges of current cancer therapy. Mounting evidence suggests that cancer stem cells (CSCs) play an important role in cancer development...

    Authors: Qiuping Liu, Zongliang Guo, Guoyin Li, Yunxia Zhang, Xiaomeng Liu, Bing Li, Jinping Wang and Xiaoyan Li
    Citation: Cancer Cell International 2023 23:305
  38. Gastric cancer (GC) causes millions of cancer-related deaths due to anti-apoptosis and rapid proliferation. However, the molecular mechanisms underlying GC cell proliferation and anti-apoptosis remain unclear....

    Authors: Lei Xiao, Yang zhang, Qingqing Luo, Cao Guo, Zihua Chen and Chen Lai
    Citation: Cancer Cell International 2023 23:304
  39. Glucose transporter 3 (GLUT3) plays a major role in glycolysis and glucose metabolism in cancer cells. We aimed to investigate the correlation between GLUT3 and histone lactylation modification in the occurren...

    Authors: Hao Yang, Shifeng Yang, Jixing He, Wenqiang Li, Ange Zhang, Nana Li, Guangkai Zhou and Boshi Sun
    Citation: Cancer Cell International 2023 23:303
  40. Acute myeloid leukemia (AML) with FMS-like tyrosine kinase 3 internal tandem duplication (FLT3-ITD) mutation accounts for a large proportion of AML patients and diagnosed with poor prognosis. Although the prog...

    Authors: Xinhua Xiao, Peihong Wang, Weina Zhang, Jiayi Wang, Mansi Cai, Hua Jiang, Yingli Wu and Huizhuang Shan
    Citation: Cancer Cell International 2023 23:302
  41. T lymphoma invasion and metastasis 1 (Tiam1) is a tumor related gene that specifically activates Rho-like GTPases Rac1 and plays a critical role in the progression of various malignancies. Glycolysis plays an ...

    Authors: Ying Liu, Aihua Jin, Xianglan Quan, Xionghu Shen, Houkun Zhou, Xingyu Zhao and Zhenhua Lin
    Citation: Cancer Cell International 2023 23:301
  42. Glucose metabolism is associated with the development of cancers, and m6A RNA methylation regulator-related genes play vital roles in bladder urothelial carcinoma (BLCA). However, the role of m6A-related gluco...

    Authors: Guanwen Zhou, Yi Li, Xiangguo Ren, Guoliang Qin, Zhaocun Zhang, Haifeng Zhao, Lijian Gao and Xianzhou Jiang
    Citation: Cancer Cell International 2023 23:300
  43. Brain metastasis is a common complication among patients with lung cancer, yet the underlying mechanisms remain unclear. In this study, we aimed to investigate the pathogenesis of brain metastasis in lung cancer.

    Authors: Jung Eun Lee, Jihye Park, Eun Ju Kim, Yoon Ho Ko, Soon Auck Hong, Seung Ho Yang and Young-Ho Ahn
    Citation: Cancer Cell International 2023 23:299
  44. Methyltransferase-like 3 (METTL3) is the key subunit of methyltransferase complex responsible for catalyzing N6-methyladenosine (m6A) modification on mRNA, which is the most prevalent post-transcriptional modific...

    Authors: Qingbin Liu, Jingjing Qi, Weiyang Li, Xinchen Tian, Jiaqi Zhang, Fen Liu, Xiulian Lu, Hengchang Zang, Chenqiao Liu, Changlin Ma, Yong Yu and Shulong Jiang
    Citation: Cancer Cell International 2023 23:298
  45. Acute myeloid leukemia (AML) is a clonal malignant disorder which originates from a small number of leukemia-initiating cells or leukemic stem cells (LSCs)—the subpopulation that is also the root cause of rela...

    Authors: Phatchanat Klaihmon, Sudjit Luanpitpong, Xing Kang and Surapol Issaragrisil
    Citation: Cancer Cell International 2023 23:297

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