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  1. Hepatocellular carcinoma (HCC) is widely recognized for its unfavorable prognosis. Increasing evidence has revealed that LGALS3 has an essential function in initiating and developing several malignancies in hu...

    Authors: Yinghui Ren, Yongmei Qian, Qicheng Zhang, Xiaoping Li, Mingjiang Li, Wei Li, Pan Yang, Hengchang Ren, Hongxia Li, Yiqi Weng, Dengwen Li, Ke Xu and Wenli Yu
    Citation: Cancer Cell International 2024 24:142
  2. Prompt identification and assessment of the disease are essential for reducing the death rate associated with colorectal cancer (COL). Identifying specific causal or sensitive components, such as coding RNA (c...

    Authors: Navid Abedpoor, Farzaneh Taghian, Khosro Jalali Dehkordi and Kamran Safavi
    Citation: Cancer Cell International 2024 24:141
  3. The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is crucial for enhancing cellula...

    Authors: Chia-Jung Li, Yen-Dun Tony Tzeng, Jui-Hu Hsiao, Ling-Ming Tseng, Tzu-Sheng Hsu and Pei-Yi Chu
    Citation: Cancer Cell International 2024 24:140
  4. Immunogenic cell death (ICD) is closely related to anti-tumor therapy and regulates the tumor microenvironment (TME). This study aims to explore the molecular characteristics of ICD in acute myeloid leukemia (...

    Authors: Fangmin Zhong, Shuyang He, Ni Guo, Luyi Shi, Linlin Zhang, Hua Jin and Guangyao Kong
    Citation: Cancer Cell International 2024 24:139
  5. N6-methyladenosine (m6A) is important in regulating mRNA stability, splicing, and translation, and it also contributes to tumor development. However, there is still limited understanding of the comprehensive e...

    Authors: Yunxing Shi, Kai Li, Yichuan Yuan, Chenwei Wang, Zhiwen Yang, Dinglan Zuo, Yi Niu, Jiliang Qiu, Binkui Li, Yunfei Yuan and Wei He
    Citation: Cancer Cell International 2024 24:138
  6. Exosomes derived from tumor cells contribute to the pathogenesis of cancers. Metformin, the most usually used drug for type 2 diabetes, has been frequently investigated for anticancer effects. Here, we examine...

    Authors: Reza Abbasi, Vahid Nejati and Jafar Rezaie
    Citation: Cancer Cell International 2024 24:137
  7. Hydrogen sulfide (H2S) is a significant endogenous mediator that has been implicated in the progression of various forms of cancer including breast cancer (BC). Cystathionine-β-synthase (CBS), cystathionine-γ-lya...

    Authors: Alyaa Dawoud, Rana A. Youness, Heba Nafea, Tamer Manie, Carole Bourquin, Csaba Szabo, Reham M. Abdel-Kader and Mohamed Z. Gad
    Citation: Cancer Cell International 2024 24:136
  8. One of the contributing factors in the diagnosis and treatment of most cancers is the identification of their surface antigens. Cancer tissues or cells have their specific antigens. Some antigens that are pres...

    Authors: Tina Nayerpour Dizaj, Abolfazl Doustmihan, Behnaz Sadeghzadeh Oskouei, Morteza Akbari, Mehdi Jaymand, MirAhmad Mazloomi and Rana Jahanban-Esfahlan
    Citation: Cancer Cell International 2024 24:135
  9. Some noncoding RNAs (ncRNAs) carry open reading frames (ORFs) that can be translated into micropeptides, although noncoding RNAs (ncRNAs) have been previously assumed to constitute a class of RNA transcripts w...

    Authors: He Zhou, Yan Wu, Ji Cai, Dan Zhang, Dongfeng Lan, Xiaofang Dai, Songpo Liu, Tao Song, Xianyao Wang, Qinghong Kong, Zhixu He, Jun Tan and Jidong Zhang
    Citation: Cancer Cell International 2024 24:134
  10. The metabolism of cancer cells generally differs from that of normal cells. Indeed, most cancer cells have a high rate of glycolysis, even at normal oxygen concentrations. These metabolic properties can potent...

    Authors: Claire Muller, Victorine Lacroix-Malgras, Jérôme Kluza, William Laine, Yonca Güler, Frédéric Bost, Michel Boisbrun, Sabine Mazerbourg and Stéphane Flament
    Citation: Cancer Cell International 2024 24:132
  11. Extensive exploration of the molecular subtypes of triple-negative breast cancer (TNBC) is critical for advancing precision medicine. Notably, the luminal androgen receptor (LAR) subtype has attracted attentio...

    Authors: Ya-Xin Zhao, Han Wang, Si-Wei Zhang, Wei-Xin Zhang, Yi-Zhou Jiang and Zhi-Ming Shao
    Citation: Cancer Cell International 2024 24:131
  12. Fatty acids synthesis and metabolism (FASM)-driven lipid mobilization is essential for energy production during nutrient shortages. However, the molecular characteristics, physiological function and clinical p...

    Authors: Ai Zhengdong, Xing Xiaoying, Fu Shuhui, Liang Rui, Tang Zehui, Song Guanbin, Yang Li, Tang Xi and Liu Wanqian
    Citation: Cancer Cell International 2024 24:130
  13. Cancer-associated fibroblasts (CAFs) drive cancer progression and treatment failure on one hand, while their tumor-restraining functions are also observed on the other. Recent single cell RNA sequencing (scRNA...

    Authors: Ze Gao, Ning Zhang, Bingzheng An, Dawei Li, Zhiqing Fang and Dawei Xu
    Citation: Cancer Cell International 2024 24:127
  14. Bladder cancer (BCa) stands out as a prevalent and highly lethal malignancy worldwide. Chemoresistance significantly contributes to cancer recurrence and progression. Traditional Tumor Node Metastasis (TNM) st...

    Authors: Tingting Cai, Tao Feng, Guangren Li, Jin Wang, Shengming Jin, Dingwei Ye and Yiping Zhu
    Citation: Cancer Cell International 2024 24:125
  15. Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent renal cancers, and the molecular mechanisms underlying its progression are still not fully understood. The expression of CCDC25, a notably u...

    Authors: Hongpei Tan, Jiahao Liu, Yanan Li, Ze Mi, Baiying Liu and Pengfei Rong
    Citation: Cancer Cell International 2024 24:124
  16. GBM, also known as glioblastoma multiforme, is the most prevalent and lethal type of brain cancer. The cell proliferation, invasion, angiogenesis, and treatment of gliomas are significantly influenced by oxida...

    Authors: Kan Wang, Yifei Xiao, Ruipeng Zheng and Yu Cheng
    Citation: Cancer Cell International 2024 24:123
  17. Prostate cancer (PCa) is one of the most prevalent cancers in men and is associated with high mortality and disability rates. β-hydroxybutyrate (BHB), a ketone body, has received increasing attention for its r...

    Authors: Yifan Zhang and Yunlong Li
    Citation: Cancer Cell International 2024 24:121
  18. Triple-negative breast cancer (TNBC) is widely recognized as the most aggressive form of breast cancer, occurring more frequently in younger patients and characterized by high heterogeneity, early distant meta...

    Authors: Lijuan Weng, Jianliang Zhou, Shenchao Guo, Nong Xu and Ruishuang Ma
    Citation: Cancer Cell International 2024 24:120
  19. This study aimed to construct a model based on 23 enrolled molecules to evaluate prognoses of pT2/3N0M0 esophageal squamous cell carcinoma (ESCC) patients with up to 20 years of follow-up.

    Authors: Wen-Mei Jiang, Jia-Yuan Tian, Yi-Han Guo, Li-Hong Qiu, Xing-Yu Luo, Yang-Yu Huang, Hao Long, Lan-Jun Zhang, Peng Lin, Xin-Xin Xu, Lei-Lei Wu and Guo-Wei Ma
    Citation: Cancer Cell International 2024 24:119
  20. Increasing evidence proves that RBP7 plays a significant role in breast cancer (BC). The present study was aimed to investigate the mechanism of RBP7.

    Authors: Yue Yu, Zhihua Xu, Hao Zhou, Ruyan Xu, Jia Xu, Wenjun Liu, Yuxin Wu, Yue Qiu, Guangbo Zhang, Xue Huang and Yan Chen
    Citation: Cancer Cell International 2024 24:118
  21. Multiple myeloma (MM) is the second most common refractory hematologic cancer. Searching for new targets and prognostic markers for MM is significant.

    Authors: Hong Luo, Chengyun Pan, Li Wang, Lin Zheng, Shuyun Cao, Xiuying Hu, Tianzhen Hu, Naiqin Zhao, Qin Shang and Jishi Wang
    Citation: Cancer Cell International 2024 24:117
  22. Mesenchymal stem/stromal cells (MSCs) have been acknowledged as the most important stromal cells in the bone marrow (BM) microenvironment for physiologic hematopoiesis and the concomitant hematologic malignanc...

    Authors: Yu Lu, Chaohui Zheng, Wenxia Zhang, Xuan Liu, Ziwei Zhou, Zhenzhen Wang, Huan Hua, Zhengrong Song, Xuejun Zhang, Shuyi Liu, Leisheng Zhang and Fuxu Wang
    Citation: Cancer Cell International 2024 24:116
  23. Oral squamous cell carcinoma (OSCC) is a prevalent neoplasm worldwide, necessitating a deeper understanding of its pathogenesis. VGF nerve growth factor inducible (VGF), a neuropeptide, plays critical roles in...

    Authors: Chung-Hsien Chou, Chun-Han Yen, Chung-Ji Liu, Hsi-Feng Tu, Shu-Chun Lin and Kuo-Wei Chang
    Citation: Cancer Cell International 2024 24:115
  24. Esophageal squamous cell carcinoma (ESCC) is one of the leading causes of digestive system tumor related death in the world. Unfortunately, effective chemopreventive agent is lack for patients with ESCC in cli...

    Authors: Qiang Yuan, Yunshu Shi, Yuhan Zhang, Yaqian Shi, Zubair Hussain, Jimin Zhao, Yanan jiang, Yan Qiao, Yaping Guo, Jing Lu, Ziming Dong, Zigang Dong, Junyong Wang and Kangdong Liu
    Citation: Cancer Cell International 2024 24:114
  25. Long non-coding RNAs (lncRNAs) are key regulators of the 6-methyladenosine (m6A) epigenetic modification, playing a role in the initiation and progression of tumors. However, the regulatory mechanisms in head ...

    Authors: Meiting Rong, Ming Zhang, Feihong Dong, Ke Wu, Bingkun Cai, Jinrui Niu, Le Yang, Zhongyan Li and Hui-yi Lu
    Citation: Cancer Cell International 2024 24:113
  26. Gastric cancer (GC) remains a malignant tumor with high morbidity and mortality, accounting for approximately 1,080,000 diagnosed cases and 770,000 deaths worldwide annually. Disulfidptosis, characterized by t...

    Authors: Jie Li, Tian Yu, Juan Sun, Mingwei Ma, Zicheng Zheng, Yixuan He, Weiming Kang and Xin Ye
    Citation: Cancer Cell International 2024 24:112
  27. Gastric cancer is currently estimated to be the fifth leading common cancer in the world, and responsible for about one million new cases and an estimated 769,000 cancer-related deaths each year. WFDC21P is lo...

    Authors: Jinyao Dong, Yongqiang Lv, Debin Meng, Ruyi Shi, Feng Li, Rui Guo, Yi Wang, Jiansheng Guo and Yanyan Zhang
    Citation: Cancer Cell International 2024 24:111
  28. Resistance to targeted therapies represents a significant hurdle to successfully treating hepatocellular carcinoma (HCC). While epigenetic abnormalities are critical determinants of HCC relapse and therapeutic...

    Authors: Tao Cheng, Changli Zhou, Sicheng Bian, Kelsey Sobeck and Yahui Liu
    Citation: Cancer Cell International 2024 24:110
  29. Noninvasive biomarkers for the assessment of response to chemotherapy in advanced breast cancer (BCa) are essential for optimized therapeutic decision-making. We evaluated the potential of soluble Periostin (P...

    Authors: Li Jia, Wenwei Hu, Xu Yan, Jie Shao, Yuhong Guo, Aimin Zhang, Lianzi Yu, Yunli Zhou, Yueguo Li, Li Ren and Dong Dong
    Citation: Cancer Cell International 2024 24:109
  30. Conventional cancer treatments can cause serious side effects because they are not specific to cancer cells and can damage healthy cells. Aptamers often are single-stranded oligonucleotides arranged in a uniqu...

    Authors: Fatemeh Mahmoudian, Azin Ahmari, Shiva Shabani, Bahman Sadeghi, Shohreh Fahimirad and Fahimeh Fattahi
    Citation: Cancer Cell International 2024 24:108
  31. A higher number of tumor buds in the invasive front of colorectal cancer (CRC) specimens has been shown to contribute to a poor prognosis in CRC patients. Because macrophages (Mφs) have been demonstrated to al...

    Authors: Ichiro Kawamura, Rintaro Ohe, Kazushi Suzuki, Takanobu Kabasawa, Takumi Kitaoka, Daiichiro Takahara, Michihisa Kono, Naoya Uchiyama, Hiroaki Musha, Mitsuru Futakuchi and Fuyuhiko Motoi
    Citation: Cancer Cell International 2024 24:107
  32. Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy and the most frequently acute leukemia of stem cell precursors and the myeloid derivatives in adult. Longitudinal studies have indi...

    Authors: Leisheng Zhang, Yunyan Sun, Chun-e Xue, Shuling Wang, Xianghong Xu, Chengyun Zheng, Cunrong Chen and Dexiao Kong
    Citation: Cancer Cell International 2024 24:106
  33. Immune microenvironment and immunotherapy have become the focus and frontier of tumor research, and the immune checkpoint inhibitors has provided novel strategies for tumor treatment. Malignant pleural effusio...

    Authors: Shan Ge, Yuwei Zhao, Jun Liang, Zhongning He, Kai Li, Guanghui Zhang, Baojin Hua, Honggang Zheng, Qiujun Guo, Runzhi Qi and Zhan Shi
    Citation: Cancer Cell International 2024 24:105
  34. Breast cancer is significantly influenced by endoplasmic reticulum (ER) stress, impacting both its initiation and progression. When cells experience an accumulation of misfolded or unfolded proteins, they acti...

    Authors: Negin Karamali, Arshia Daraei, Arman Rostamlou, Roya Mahdavi, Zahra Akbari Jonoush, Nooshin Ghadiri, Zahra Mahmoudi, Amirhossein Mardi, Moslem Javidan, Sepideh Sohrabi and Behzad Baradaran
    Citation: Cancer Cell International 2024 24:104
  35. Colorectal cancer (CRC) is a malignancy of remarkable heterogeneity and heightened morbidity. Cancer associated fibroblasts (CAFs) are abundant in CRC tissues and are essential for CRC growth. Here, we aimed t...

    Authors: Zizhen Zhang, Shengde Liu, Zhenghang Wang, Shuo Wang, Lei Jiang, Xicheng Wang, Jian Li and Lin Shen
    Citation: Cancer Cell International 2024 24:103
  36. Despite advances in therapeutic strategies, resistance to immunotherapy and the off-target effects of targeted therapy have significantly weakened the benefits for patients with melanoma.

    Authors: Wanxian Chen, Deyi Geng, Jiasheng Chen, Xiaosha Han, Qihu Xie, Genghong Guo, Xuefen Chen, Wancong Zhang, Shijie Tang and Xiaoping Zhong
    Citation: Cancer Cell International 2024 24:101
  37. Allogeneic tumors are eradicated by host immunity; however, it is unknown how it is initiated until the report in Nature by Yaron Carmi et al. in 2015. Currently, we know that allogeneic tumors are eradicated by ...

    Authors: Ying Liu, Yuanyi Huang, Hong-Wei Cui, YingYing Wang, ZhaoWu Ma, Ying Xiang, Hong-Yi Xin, Jun-Qing Liang and Hong-Wu Xin
    Citation: Cancer Cell International 2024 24:100
  38. Breast cancer is a major global health concern, and there is a continuous search for novel biomarkers to predict its prognosis. The mitochondrial protein NDUFAF6, previously studied in liver cancer, is now bei...

    Authors: Baohong Jiang, Sixuan Wu, Lijun Zeng, Yuanbin Tang, Lunqi Luo, Lianjie Ouyang, Wenjie Feng, Yeru Tan and Yuehua Li
    Citation: Cancer Cell International 2024 24:99
  39. Tumor organoids, especially patient-derived organoids (PDOs) exhibit marked similarities in histopathological morphology, genomic alterations, and specific marker expression profiles to those of primary tumour...

    Authors: Rong-Xuan Ning, Cun-Yu Liu, Shi-Qi Wang, Wen-Kai Li, Xia Kong and Zhi-Wei He
    Citation: Cancer Cell International 2024 24:98
  40. Gastrointestinal cancer, one of the most common cancers, continues to be a major cause of mortality and morbidity globally. Accumulating evidence has shown that alterations in mitochondrial energy metabolism a...

    Authors: Quanling Zhou, Xiaohui Li, Honglian Zhou, Juanjuan Zhao, Hailong Zhao, Lijuan Li and Ya Zhou
    Citation: Cancer Cell International 2024 24:97
  41. N6-methyladenosine (m6A) is dysregulated in various cancers, including colorectal cancer (CRC). Herein, we assess the diagnostic potential of peripheral blood (PB) m6A levels in CRC.

    Authors: Chunying Zhang, Jiadi Chen, Jingyi Ren, Xiaoyu Li, Yaqin Zhang, Bihan Huang, Yihan Xu, Luyan Dong and Yingping Cao
    Citation: Cancer Cell International 2024 24:96

    The Correction to this article has been published in Cancer Cell International 2024 24:126

  42. The present study aimed to investigate the expression level, biological function, and underlying mechanism of transmembrane protein 176B (TMEM176B) in gastric cancer (GC).

    Authors: Jing Li, ZiQing Fang, Emre Dal, Hao Zhang, KeXun Yu, MengDi Ma, MingLiang Wang, Ruochuan Sun, MingDian Lu, HuiZhen Wang and YongXiang Li
    Citation: Cancer Cell International 2024 24:95
  43. Novel therapeutic targets are urgently needed for treating drug-resistant non-small cell lung cancer (NSCLC) and overcoming drug resistance to molecular-targeted therapies. Regulator of G protein signaling 20 ...

    Authors: Xiaoyan Ding, Xiaoxia Li, Yanxia Jiang, Yujun Li, Hong Li, Lipeng Shang, Guilin Feng, Huhu Zhang, Ziyuan Xu, Lina Yang, Bing Li and Robert Chunhua Zhao
    Citation: Cancer Cell International 2024 24:93
  44. Cholangiocarcinoma represents a malignant neoplasm originating from the hepatobiliary tree, with a subset of tumors developing inside the liver. Intrahepatic cholangiocarcinomas (ICC) commonly exhibit an asymp...

    Authors: Hefei Ren, Chang Liu, Cheng Zhang, Hongkun Wu, Jiafeng Zhang, Zhenhua Wang, Lei Chen, Huiquan Wang, Chenghao Shao and Lin Zhou
    Citation: Cancer Cell International 2024 24:92

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