Skip to main content

Articles

Page 20 of 76

  2. m6A (N6-methyladenosine) methylation, a well-known modification in tumour epigenetics, dynamically and reversibly fine tunes the entire process of RNA metabolism. Aberrant levels of m6A and its regulators, whi...

    Authors: Lin-Lin Chang, Xia-Qing Xu, Xue-Ling Liu, Qian-Qian Guo, Yan-Nan Fan, Bao-Xia He and Wen-Zhou Zhang
    Citation: Cancer Cell International 2021 21:663
    Content type: Review Published on:

  4. Gastric cancer is a highly aggressive malignant tumor with heterogeneity and is still a global health problem. The present study aimed to investigate the role of Cyclin I-like (CCNI2) in the regulation of phen...

    Authors: Wenchao Chen, Yang Zhou, Gang Wu and Peichun Sun
    Citation: Cancer Cell International 2021 21:661
    Content type: Primary Research Published on:

  5. In bladder cancer, up to 70% of patients will relapse after resection within 5 years, in which the mechanism underlying the recurrence remains largely unclear.

    Authors: Junhao Zhou, Hu Tian, Xi Zhi, Zhuoyu Xiao, Taoyi Chen, Haoyu Yuan, Qi Chen, Mingkun Chen, Jiankun Yang, Qizhao Zhou, Kangyi Xue, Wenbin Guo, Ming Xia, Jiming Bao, Cheng Yang, Haifeng Duan…
    Citation: Cancer Cell International 2021 21:660
    Content type: Primary research Published on:

  7. Prodigiosin (PG), a natural red pigment produced by numerous bacterial species, has been a eye-catching research point in recent years for its anticancer activity. However, the role of PG in the cancer biology...

    Authors: Dijie Zheng, Shiyu Chen, Kun Cai, Linhan Lei, Chunchen Wu, Chengyi Sun, Yazhu Deng and Chao Yu
    Citation: Cancer Cell International 2021 21:658
    Content type: Primary Research Published on:

  8. Intrahepatic cholangiocarcinoma (ICC) is a fatal primary liver cancer, and its long-term survival rate remains poor. RNA-binding proteins (RBPs) play an important role in critical cellular processes, failure o...

    Authors: Wenbo Zou, Zizheng Wang, Xiuping Zhang, Shuai Xu, Fei Wang, Lincheng Li, Zhaoda Deng, Jing Wang, Ke Pan, Xinlan Ge, Chonghui Li, Rong Liu and Minggen Hu
    Citation: Cancer Cell International 2021 21:657
    Content type: Primary research Published on:

  9. Accumulating evidence has demonstrated the close relation of SOX1 with tumorigenesis and tumor progression. Upregulation of SOX1 was recently shown to suppress growth of human cancers. However, the expression ...

    Authors: Da Wang, Fei Xiong, Guanhua Wu, Wenzheng Liu, Bing Wang and Yongjun Chen
    Citation: Cancer Cell International 2021 21:656
    Content type: Primary Research Published on:

  10. SWI/SNF, a well-known ATP-dependent chromatin-remodeling complex, plays an essential role in several biological processes. SNF5, the core subunit of the SWI/SNF remodeling complex, inactivated in 95% of malign...

    Authors: Hua Ding, Yaqin Huang, Jiazhong Shi, Liwei Wang, Sha Liu, Baixiong Zhao, Yuting Liu, Jin Yang and Zhiwen Chen
    Citation: Cancer Cell International 2021 21:655
    Content type: Primary Research Published on:

    The Correction to this article has been published in Cancer Cell International 2022 22:20

  11. Tumor migration and invasion is a complex and diverse process that involves the epithelial–mesenchymal transition (EMT) of tumor cells and degradation of the extracellular matrix by matrix metalloproteases (MM...

    Authors: Mengying Teng, Chunyan Hu, Bingmo Yang, Wei Xiao, Qian Zhou, Yuan Li and Zhong Li
    Citation: Cancer Cell International 2021 21:654
    Content type: Primary Research Published on:

  12. MYB is often overexpressed in malignant tumors and plays a carcinogenic role in the initiation and development of cancer. Deletion of the MYB regulatory C-terminal domain may be a driving mutation leading to t...

    Authors: Dingyu Hu, Wenjun Shao, Li Liu, Yanyan Wang, Shunling Yuan, Zhaoping Liu, Jing Liu and Ji Zhang
    Citation: Cancer Cell International 2021 21:653
    Content type: Review Published on:

  13. Aging and senescence can alter immune cell fitness and influence the efficacy of lung cancer treatments, especially immunotherapy. However, the correlations between cellular senescence and tumor microenvironme...

    Authors: Weihao Lin, Xin Wang, Zhenyi Xu, Zhen Wang, Tiejun Liu, Zheng Cao, Xiaoli Feng, Yibo Gao and Jie He
    Citation: Cancer Cell International 2021 21:652
    Content type: Primary Research Published on:

  14. Circular RNAs (circRNAs) act pivotal roles in the progression of multiple malignancies. However, the underlying mechanisms by which hsa_circ_0007031 (circTUBGCP3) contributes to lung adenocarcinoma (LAC) remai...

    Authors: Yang Yang, Xin Fan, Yunfei Nie, Donglei Liu, Dengyan Zhu, Kai Wu, Yuan Zhang, Wenhua Li, Xiangyu Tian, Huaqi Wang and Yuxia Fan
    Citation: Cancer Cell International 2021 21:651
    Content type: Primary Research Published on:

  15. Previous studies indicated CRNDE to have a pivotal part within tumorigenesis. Notwithstanding, precise details on CRNDE activities within NPC are still uncertain. The investigation described in this article se...

    Authors: Sichen Ge, Chengyi Jiang, Min Li, Zhongqiang Cheng and Xiaojia Feng
    Citation: Cancer Cell International 2021 21:650
    Content type: Primary Research Published on:

  16. The ESR1 gene suffers methylation changes in many types of cancers, including breast cancer (BC), the most frequently diagnosed cancer in women that is also present in men. Methylation at promoter A of ESR1 is th...

    Authors: Laura Itzel Quintas-Granados, Hernán Cortés, Manuel González-Del Carmen, Gerardo Leyva-Gómez, Lilia Patricia Bustamante-Montes, Miguel Rodríguez-Morales, Edgar Yebran Villegas-Vazquez, Israel López-Reyes, Sofía Lizeth Alcaraz-Estrada, Jorge Sandoval-Basilio, Ernesto Soto-Reyes, Javad Sharifi-Rad, Gabriela Figueroa-González and Octavio Daniel Reyes-Hernández
    Citation: Cancer Cell International 2021 21:649
    Content type: Primary Research Published on:

  17. Osteosarcoma (OS) patients with lung metastasis have poor prognoses, and effective therapeutic strategies for delaying or inhibiting the spread of lung metastasis from the primary OS site are lacking. Hence, i...

    Authors: Haoran Kong, Wenhui Yu, Zhuning Chen, Haonan Li, Guiwen Ye, Jiacong Hong, Zhongyu Xie, Keng Chen, Yanfeng Wu and Huiyong Shen
    Citation: Cancer Cell International 2021 21:648
    Content type: Primary Research Published on:

    The Correction to this article has been published in Cancer Cell International 2022 22:152

  19. Eribulin has shown antitumour activity in some soft tissue sarcomas (STSs), but it has only been approved for advanced liposarcoma (LPS).

    Authors: Javier Escudero, Victoria Heredia-Soto, Yinyin Wang, Patricia Ruiz, Yingying Hu, Alejandro Gallego, Jose Juan Pozo-Kreilinger, Virginia Martinez-Marin, Alberto Berjon, Eduardo Ortiz-Cruz, Daniel Bernabeu, Jaime Feliu, Jing Tang, Andres Redondo and Marta Mendiola
    Citation: Cancer Cell International 2021 21:646
    Content type: Primary Research Published on:

  20. Glioma is a common type of malignant brain tumor with a high mortality and relapse rate. The endosomal sorting complex required for transport (ESCRT) has been reported to be involved in tumorigenesis. However,...

    Authors: Xiaolong Zhu, Hui Yang, Mengying Zhang, Xingwei Wu, Lan Jiang, Xiaocen Liu and Kun Lv
    Citation: Cancer Cell International 2021 21:645
    Content type: Primary research Published on:

  21. The lncRNA H19 is believed to act as an oncogene in various types of tumors and is considered to be a therapeutic target and diagnostic marker. However, the role of the lncRNA H19 in regulating the radiosensit...

    Authors: Xueshan Zhao, Xiaodong Jin, Qiuning Zhang, Ruifeng Liu, Hongtao Luo, Zhen Yang, Yichao Geng, Shuangwu Feng, Chengcheng Li, Lina Wang, Xiaohu Wang and Qiang Li
    Citation: Cancer Cell International 2021 21:644
    Content type: Primary research Published on:

  22. Human papillomavirus (HPV) E6/E7 mRNA in situ hybridization (HPV E6/E7 RNAscope) appears to be a sensitive and specific technique in detecting transcriptionally active HPV. We aimed to examine the diagnostic u...

    Authors: Rong-Zhen Luo, Shu-Lin Chen, Mei Li, Yue Li, Xia Yang and Li-Li Liu
    Citation: Cancer Cell International 2021 21:643
    Content type: Primary Research Published on:

  24. Heterogeneous nuclear ribonucleoprotein K (HnRNPK) is a nucleic acid-binding protein that regulates diverse biological events. Pathologically, HnRNPK proteins are frequently overexpressed and clinically correl...

    Authors: Huan-Lei Wu, Sen-Mao Li, Yao-chen Huang, Qi-Dong Xia, Peng Zhou, Xian-Miao Li, Xiao Yu, Shao-Gang Wang, Zhang-Qun Ye and Jia Hu
    Citation: Cancer Cell International 2021 21:641
    Content type: Primary Research Published on:

  25. Osteosarcoma (OS) metastasis is the most common cause of cancer-related mortality, however, no sufficient clinical biomarkers have been identified. In this study, we identified five genes to help predict metas...

    Authors: Fu-peng Ding, Jia-yi Tian, Jing Wu, Dong-feng Han and Ding Zhao
    Citation: Cancer Cell International 2021 21:640
    Content type: Primary research Published on:

  26. Cervical cancer (CC) is the leading cause of cancer-related death in women. A limited number of studies have investigated whether immune-prognostic features can be used to predict the prognosis of CC. This stu...

    Authors: Ya-Nan Pi, Jun-Nan Guo, Ge Lou and Bin-Bin Cui
    Citation: Cancer Cell International 2021 21:639
    Content type: Primary Research Published on:

  27. The emergence of chemoresistance to 5-fluorouracil (5-FU)-based chemotherapy is the main cause of treatment failure in advanced and metastatic colorectal cancer (CRC) patients. Long noncoding RNAs (lncRNAs) ha...

    Authors: Jingui Wang, Xiaoqian Zhang, Junling Zhang, Shangwen Chen, Jing Zhu and Xin Wang
    Citation: Cancer Cell International 2021 21:638
    Content type: Primary Research Published on:

  28. Esophageal carcinogenesis is a multifactorial process in which genetic and environmental factors interact to activate intracellular signals, leading to the uncontrolled survival and growth of esophageal squamo...

    Authors: Jia Zhao, Guangyu Jin, Xudong Liu, Kai Wu, Yang Yang, Zhanfeng He, Donglei Liu, Chunyang Zhang, Dengyan Zhu, Jia Jiao, Xiangnan Li and Song Zhao
    Citation: Cancer Cell International 2021 21:637
    Content type: Primary Research Published on:

  29. Circular RNAs (circRNAs), which are endogenous non-coding RNAs, are associated with various biological processes including development, homeostatic maintenance, and pathological responses. Accumulating evidenc...

    Authors: Yu Huang, Wenhao Ge, Yuan Ding, Lufei Zhang, Jiarong Zhou, Yang Kong, Bijun Cui, Bingqiang Gao, Xiaohui Qian and Weilin Wang
    Citation: Cancer Cell International 2021 21:636
    Content type: Primary Research Published on:

  30. The tumor microenvironment (TME) is critical in the progression and metastasis of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) and their gene expression have been linke...

    Authors: Peipei Yang, Wanrong Chen, Hua Xu, Junhan Yang, Jinghang Jiang, Yunhui Jiang and Ganglin Xu
    Citation: Cancer Cell International 2021 21:635
    Content type: Primary Research Published on:

  31. Rhabdomyosarcoma (RMS) is a malignant soft-tissue tumour. In recent years, the tumour microenvironment (TME) has been reported to be associated with the development of tumours. However, the relationship betwee...

    Authors: Tian Xia, Lian Meng, Zhijuan Zhao, Yujun Li, Hao Wen, Hao Sun, Tiantian Zhang, Jingxian Wei, Feng Li and Chunxia Liu
    Citation: Cancer Cell International 2021 21:634
    Content type: Primary Research Published on:

  32. Current treatment options for glioma are limited, and the prognosis of patients with glioma is poor as the available drugs show low therapeutic efficacy. Furthermore, the molecular mechanisms associated with g...

    Authors: Lun Li, Yi Yang, Zhenshuang Wang, Chengran Xu, Jinhai Huang and Guangyu Li
    Citation: Cancer Cell International 2021 21:633
    Content type: Primary Research Published on:

  33. The precancerous disease of breast cancer is an inevitable stage in the tumorigenesis and development of breast neoplasms. Quercetin (Que) has shown great potential in breast cancer treatment by inhibiting cel...

    Authors: Dan Qiu, Xianxin Yan, Xinqin Xiao, Guijuan Zhang, Yanqiu Wang, Jingyu Cao, Ruirui Ma, Shouyi Hong and Min Ma
    Citation: Cancer Cell International 2021 21:632
    Content type: Primary Research Published on:

  34. A number of studies have indicated that Ubiquitin-conjugating enzyme E2T (UBE2T), as an oncogene, promotes progression and metastasis of lung cancer, including lung adenocarcinoma (LUAD), but it is completely ...

    Authors: Yongbing Chen, Haihua Hong, Qingqing Wang, Junqiang Li, Wenfeng Zhang, Tingting Chen and Pu Li
    Citation: Cancer Cell International 2021 21:631
    Content type: Primary Research Published on:

  35. Osteosarcoma is a primary malignant tumor that mainly affects children and young adults. Transmembrane emp24 trafficking protein 3 (TMED3) may be involved in the regulation of malignant cancer behaviors. Howev...

    Authors: Wei Xu, Yifan Li, Xiaojian Ye, Yunhan Ji, Yu Chen, Xiangyang Zhang and Zhikun Li
    Citation: Cancer Cell International 2021 21:630
    Content type: Primary Research Published on:

  36. MicroRNA (miRNA) that translocate from the nucleus to mitochondria are referred to as mitochondrial microRNA (mitomiR). Albeit mitomiRs have been shown to modulate gene expression, their functional impact with...

    Authors: Praveen Sharma, Vibhuti Sharma, Tarunveer Singh Ahluwalia, Nilambra Dogra, Santosh Kumar and Sandeep Singh
    Citation: Cancer Cell International 2021 21:629
    Content type: Primary Research Published on:

  37. Non-small cell lung cancer (NSCLC) accounts for more than 80% of lung cancers, which is the most common malignant tumor worldwide. Polypeptide extract from scorpion venom (PESV) has been reported to inhibit NS...

    Authors: Hong Zhang, Haojian Zhang, Jiye Zhu, Huan Liu and Qin Zhou
    Citation: Cancer Cell International 2021 21:628
    Content type: Primary Research Published on:

  38. Cancer cachexia is a wasting disorder characterized by significant weight loss, and is attributed to skeletal muscle weakness. In the process of cancer development, microRNAs act as oncogenes or tumor suppress...

    Authors: Kairu Xie, Hairong Xiong, Wen Xiao, Zhiyong Xiong, Wenjun Hu, Jiaxin Ye, Ning Xu, Jian Shi, Changfei Yuan, Zhixian Chen, Daojia Miao, Xiaoping Zhang and Hongmei Yang
    Citation: Cancer Cell International 2021 21:627
    Content type: Primary Research Published on:

  39. Controversial findings have been reported in the impact of speckle-type POZ protein (SPOP) on clinicopathological features and prognosis in diverse cancers. We conducted this meta-analysis to confirm whether S...

    Authors: Yan He, Jun Chen, Xingchen Peng, Yanli Xia and Yonglin Su
    Citation: Cancer Cell International 2021 21:626
    Content type: Review Published on:

  40. This article aimed to explore the prognostic and immunological roles of AXL gene in clear cell renal cell carcinoma (ccRCC) for overall survival (OS) and to identify the LncRNA/RBP/AXL mRNA networks.

    Authors: Yi Wang, Ye Tian, Shouyong Liu, Zengjun Wang and Qianwei Xing
    Citation: Cancer Cell International 2021 21:625
    Content type: Primary Research Published on:

  41. Long non-coding RNAs (lncRNAs) have been verified to play fatal role in regulating the progression of lung adenocarcinoma (LUAD). Although lncRNAs play important role in regulating the autophagy of tumor cells...

    Authors: Zhuochen Zhao, Junhu Wan, Manman Guo, Zhengwu Yang, Zhuofang Li, Yangxia Wang and Liang Ming
    Citation: Cancer Cell International 2021 21:624
    Content type: Primary Research Published on:

  42. Acquired glucocorticoid (GC) resistance remains the main obstacle in acute lymphoblastic leukemia (ALL) therapy. The aim of the present study was to establish a novel GC-resistant B-ALL cell line and investiga...

    Authors: Yuanyuan Li, Chuan Zuo and Ling Gu
    Citation: Cancer Cell International 2021 21:623
    Content type: Primary Research Published on:

  43. Morphine, a µ-opioid receptor (MOR) agonist, has been shown to be related to the activity of cancer cells, and a higher morphine dosage reduces the survival time of patients with lung cancer. However, the effe...

    Authors: Xingyun Liu, Jia Yang, Chengwei Yang, Xiang Huang, Mingming Han, Fang Kang and Juan Li
    Citation: Cancer Cell International 2021 21:622
    Content type: Primary Research Published on:

  44. The aim of this study was to construct a model based on the prognostic features associated with epithelial–mesenchymal transition (EMT) to explore the various mechanisms and therapeutic strategies available fo...

    Authors: Dafeng Xu, Yu Wang, Jincai Wu, Shixun Lin, Yonghai Chen and Jinfang Zheng
    Citation: Cancer Cell International 2021 21:621
    Content type: Primary Research Published on:

  45. Pancreatic cancer has been a threateningly lethal malignant tumor worldwide. Despite the promising survival improvement in other cancer types attributing to the fast development of molecular precise medicine, ...

    Authors: Rong Wei, Guoye Qi, Zixin Zeng, Ningning Shen, Ziyue Wang, Honghong Shen, Lifang Gao, Chen Song, Wenxia Ma and Chen Wang
    Citation: Cancer Cell International 2021 21:620
    Content type: Primary Research Published on:

  46. Neuroblastoma (NB) is a common solid malignancy in children that is associated with a poor prognosis. Although the novel small molecular compound Dimethylaminomicheliolide (DMAMCL) has been shown to induce cel...

    Authors: Simeng Zhang, Zhongyan Hua, Gen Ba, Ning Xu, Jianing Miao, Guifeng Zhao, Wei Gong, Zhihui Liu, Carol J. Thiele and Zhijie Li
    Citation: Cancer Cell International 2021 21:619
    Content type: Primary Research Published on:

  47. Papillary thyroid carcinoma (PTC) is a common endocrine tumor. Increasing evidence has shown that microRNA dysfunction is involved in the occurrence and development of cancer. The expression of MicroRNA-30b-5p...

    Authors: Ye Wang, Congjun Wang, Zhao Fu, Siwen Zhang and Junqiang Chen
    Citation: Cancer Cell International 2021 21:618
    Content type: Primary Research Published on:

  49. There is mounting evidence that demonstrated the association of aberrant NEDD4L expression with diverse human cancers. However, the expression pattern and clinical implication of NEDD4L in acute myeloid leukemia ...

    Authors: Ming-qiang Chu, Liu-chao Zhang, Qian Yuan, Ting-juan Zhang and Jing-dong Zhou
    Citation: Cancer Cell International 2021 21:615
    Content type: Primary Research Published on:

  50. Most previous studies compared the risk for non-melanoma skin cancer (NMSC) in biologic-treated common inflammatory diseases with the general population. Whether the increased NMSC risk is caused by the diseas...

    Authors: Ruolin Liu, Qianyi Wan, Rui Zhao, Haitao Xiao, Ying Cen and Xuewen Xu
    Citation: Cancer Cell International 2021 21:614
    Content type: Review Published on:
Journal cover image
Submit manuscript

Follow

Annual Journal Metrics

  • 2022 Citation Impact
    5.8 - 2-year Impact Factor
    5.6 - 5-year Impact Factor
    0.994 - SNIP (Source Normalized Impact per Paper)
    1.145 - SJR (SCImago Journal Rank)

    2023 Speed
    34 days submission to first editorial decision for all manuscripts (Median)
    110 days submission to accept (Median)

    2023 Usage 
    2,067,719 downloads
    1,052 Altmetric mentions 

On the blog

Institutional membership

Visit the membership page to check if your institution is a member and learn how you could save on article-processing charges (APCs).

Funding your APC

​​​​​​​Open access funding and policy support by SpringerOpen​​

​​​​We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here. 

Cancer Cell International

ISSN: 1475-2867

Contact us