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  1. Gastric cancer is a frequent and lethal solid tumor that has a poor prognosis and treatment result. Reprogramming of nucleotide metabolism is a characteristic of cancer development and progression.

    Authors: Shaofei Chen and Zhiyong Wang
    Citation: Cancer Cell International 2024 24:212
  2. MicroRNA-98 (miR-98) stands as an important molecule in the intricate landscape of oncology. As a subset of microRNAs, these small non-coding RNAs have accompanied a new era in cancer research, underpinning their...

    Authors: Vajihe Hazari, Sahar Ahmad Samali, Payam Izadpanahi, Homa Mollaei, Farzad Sadri and Zohreh Rezaei
    Citation: Cancer Cell International 2024 24:209
  3. Lung adenocarcinoma (LUAD) patients have a dismal survival rate because of cancer metastasis and drug resistance. The study aims to identify the genes that concurrently modulate EMT, metastasis and EGFR-TKI re...

    Authors: Weina Fan, Ying Xing, Shi Yan, Wei Liu, Jinfeng Ning, Fanglin Tian, Xin Wang, Yuning Zhan, Lixin Luo, Mengru Cao, Jian Huang and Li Cai
    Citation: Cancer Cell International 2024 24:208
  4. Human liver cancer stem-like cells (HLCSLCs) are widely acknowledged as significant factors in the recurrence and eradication of hepatocellular carcinoma (HCC). The sustenance of HLCSLCs’ stemness is hypothesi...

    Authors: Lei Lou, Tingyun Deng, Qing Yuan, Lianghou Wang, Zhi Wang and Xiang Li
    Citation: Cancer Cell International 2024 24:206
  5. The members of the classic B7 family regulate the immune microenvironment of several malignant tumors. However, the potential relationship between the B7 family and the breast cancer (BrCa) tumor immune microe...

    Authors: Jiayu Liu, Cenzhu Wang, Ying Jiang, Yunxu Zhou, Lingyan Chen, Zhiwen Qian, Lu Liu, Danping Wu and Yan Zhang
    Citation: Cancer Cell International 2024 24:205
  6. Aberrant Derlin-1 (DERL1) expression is associated with an overactivation of p-AKT, whose involvement in breast cancer (BRCA) development has been widely speculated. However, the precise mechanism that links D...

    Authors: Yang Bai, Zhanqiang Zhang, Jiong Bi, Qian Tang, Keying Jiang, Chen Yao and Wenjian Wang
    Citation: Cancer Cell International 2024 24:204
  7. Prostate cancer (PC) is a major global health concern affecting male individuals. Among its variants, androgen-independent prostate cancer exhibits slow progression and lacks effective treatment targets, rende...

    Authors: Ying Chang, Jinyuan Sui, Qiang Fu, Zhongqi Lu, Zhengri Piao, Tiefeng Jin and Meihua Zhang
    Citation: Cancer Cell International 2024 24:203
  8. Colorectal cancer (CRC) has the third highest incidence and second mortality rate of malignant tumors globally, highlighting the urgency to explore the mechanisms underlying CRC progression for refined treatme...

    Authors: Wenjie Zhu, Changlei Wu, Zitao Liu, Shimin Zhao, Xiufeng Cheng and Jun Huang
    Citation: Cancer Cell International 2024 24:201
  9. Ferroptosis, an iron-dependent regulated cell death mechanism, holds significant promise as a therapeutic strategy in oncology. In the current study, we explored the regulatory effects of epigallocatechin gall...

    Authors: Shun Wang, Ruohuang Wang, Dingtao Hu, Caoxu Zhang, Peng Cao, Jie Huang and Baoqing Wang
    Citation: Cancer Cell International 2024 24:200
  10. The extracellular matrix (ECM) is a dynamic and complex microenvironment that modulates cell behavior and cell fate. Changes in ECM composition and architecture have been correlated with development, different...

    Authors: Madison R. Pickett, Yuan-I Chen, Mohini Kamra, Sachin Kumar, Nikhith Kalkunte, Gabriella P. Sugerman, Kelsey Varodom, Manuel K. Rausch, Janet Zoldan, Hsin-Chin Yeh and Sapun H. Parekh
    Citation: Cancer Cell International 2024 24:199
  11. Translationally controlled tumor protein (TCTP), also known as histamine-releasing factor (HRF) or fortilin, is a highly conserved protein found in various species. To date, multiple studies have demonstrated ...

    Authors: An-Bu Liu, Jia Liu, Sheng Wang, Lei Ma and Jun-Fei Zhang
    Citation: Cancer Cell International 2024 24:198
  12. Syntaxin6 (STX6) is a SNARE (Soluble N-ethylmaleimide-sensitive factor attachment protein receptors) protein complex located in the trans-Golgi network and endosomes, which is closely associated with a variety...

    Authors: Li Huang, Xiaoting Zhong, An Li, Fuping Tu, Miao He, Xueming Xu, Xiaohui Liu, Xiaoli Zeng, Jun Chi, Tian Tian, Chunli Wang, Xiangcai Wang and Jianming Ye
    Citation: Cancer Cell International 2024 24:197
  13. Thyroid cancer (TC) is the most common endocrine malignancy. Nowadays, undifferentiated thyroid cancers (UTCs) are still lethal, mostly due to the insurgence of therapy resistance and disease relapse. These ev...

    Authors: Viola Ghiandai, Elisa Stellaria Grassi, Giacomo Gazzano, Laura Fugazzola and Luca Persani
    Citation: Cancer Cell International 2024 24:196
  14. Hepatocellular carcinoma (HCC) is a highly prevalent and deadly cancer, with limited treatment options for advanced-stage patients. Disulfidptosis is a recently identified mechanism of programmed cell death th...

    Authors: Guanjun Chen, Ganghua Zhang, Yuxing Zhu, Anshan Wu, Jianing Fang, Zhijing Yin, Haotian Chen and Ke Cao
    Citation: Cancer Cell International 2024 24:194
  15. LncRNA colorectal neoplasia differentially expressed (CRNDE) was found to be an important regulator in many cancers. This project focuses on the function of CRNDE on macrophage metabolic reprogramming and Hepa...

    Authors: Chao Lin, Tao Jiang, Changyong E, Lun Wang, Tong Chen, Xia Wang and Yien Xiang
    Citation: Cancer Cell International 2024 24:193
  16. Immunotherapy combined with molecular targeted therapy is increasingly popular in patients with advanced hepatocellular carcinoma (HCC). However, immune-related adverse events(irAEs) brought on by immunotherap...

    Authors: Guoqiang Sun, Chuan Liu, Zhengqing Lu, Jinyu Zhang, Hengsong Cao, Tian Huang, Mingrui Dai, Hanyuan Liu, Tingting Feng, Weiwei Tang and Yongxiang Xia
    Citation: Cancer Cell International 2024 24:192
  17. Mitogen-activated protein kinase inhibitors (MAPKi) were the first line drugs for advanced melanoma patients with BRAF mutation. Targeted therapies have significant therapeutic effects; however, drug resistanc...

    Authors: Kun Zhao, Qi Zhao, Xinzhi Dai, Xue Wen, Xing Luo, Yi Duan, Zhihui Yang and Qiong Dai
    Citation: Cancer Cell International 2024 24:191
  18. Cancer-associated fibroblasts (CAFs) are the major cellular component of the tumor microenvironment and are known to affect tumor growth and response to various treatments. This study was undertaken to investi...

    Authors: Max Rademaekers, Emil Oliver Johansson, Ellen Johansson, Karin Roberg and Emilia Wiechec
    Citation: Cancer Cell International 2024 24:190
  19. The advancement of nanoscience and material design in recent times has facilitated the creation of point-of-care devices for cancer diagnosis and biomolecule sensing. Exosomes (EXOs) facilitate the transfer of...

    Authors: Saman Yasamineh, Naghmeh Nikben, Mareb Hamed Ahmed, Radhwan Abdul Kareem, Ameer Kadhim Al-Aridhy and Mohammad Hosseini Hooshiar
    Citation: Cancer Cell International 2024 24:189
  20. Breast cancer is a serious threat to women’s health with high morbidity and mortality. The development of more effective therapies for the treatment of breast cancer is strongly warranted. Growing evidence sug...

    Authors: Yun-Qi Zhang, Wei Zhang, Xiang-Tai Kong, Wang-Xi Hai, Rui Guo, Min Zhang, Su-Lin Zhang and Biao Li
    Citation: Cancer Cell International 2024 24:188
  21. Chronic myeloid leukemia (CML) is a common hematological malignancy, and tyrosine kinase inhibitors (TKIs) represent the primary therapeutic approach for CML. Activation of metabolism signaling pathway has bee...

    Authors: Yifei Li, Shiyi Yuan, Ying Zhou, Jingwen Zhou, Xuan Zhang, Ping Zhang, Wenrui Xiao, Ying Zhang, Jianchuan Deng and Shifeng Lou
    Citation: Cancer Cell International 2024 24:186
  22. The aim of this study was to determine the role of lncRNA PART1 and downstream FUT6 in tumorigenesis and progression of head and neck cancer (HNC). Bioinformatics analysis and qRT-PCR revealed that lncRNA PART...

    Authors: Yanheng Yao, Yuxin Zhang, Jiyuan Shi, Xiling Xu, Yunran Gao, Suwen Bai, Qin Hu, Jing Wu and Juan Du
    Citation: Cancer Cell International 2024 24:185
  23. Cancer-induced pre-metastatic niches (PMNs) play a decisive role in promoting metastasis by facilitating angiogenesis in distant sites. Evidence accumulates suggesting that microRNAs (miRNAs) exert significant...

    Authors: Yilin Hu, Weijie Zang, Ying Feng, Qinsheng Mao, Junjie Chen, Yizhun Zhu and Wanjiang Xue
    Citation: Cancer Cell International 2024 24:184
  24. Immune checkpoint inhibitors are approved for the treatment of various tumors, but the response rate is not satisfactory in certain malignancies. Inhibitor of apoptosis proteins (IAP) ubiquitin-E3 ligase activ...

    Authors: Wentao Pan, Qiuyun Luo, Eric Liang, Mude Shi, Jian Sun, Huimin Shen, Zhenhai Lu, Lin Zhang, Xianglei Yan, Luping Yuan, Suna Zhou, Hanjie Yi, Yifan Zhai, Miao-zhen Qiu and Dajun Yang
    Citation: Cancer Cell International 2024 24:181
  25. Although rare, uveal melanoma (UM) is a life-threatening malignancy. Understanding its biology is necessary to improve disease outcome. Three-dimensional (3D) in vitro culture methods have emerged as tools tha...

    Authors: Alicia A. Goyeneche, Jade M. E. Lasiste, Mohamed Abdouh, Prisca Bustamante, Julia V. Burnier and Miguel N. Burnier Jr.
    Citation: Cancer Cell International 2024 24:180
  26. Radiotherapy (RT) has been identified as a vital treatment for esophageal squamous cell carcinoma (ESCC), while the development of radioresistance remains a major obstacle in ESCC management. The aim of this s...

    Authors: Dong Guo, Shuo Zhou, Ruixue Liu, Weinan Yao, Shuguang Li, Xueyuan Zhang, Wenbin Shen and Shuchai Zhu
    Citation: Cancer Cell International 2024 24:179
  27. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors worldwide, with extremely aggressive and complicated biology. Krüppel-like factors (KLFs) encode a series of transcriptional regulatory pr...

    Authors: Jiayu Lin, Pengyi Liu, Keyan Sun, Lingxi Jiang, Yang Liu, Yishu Huang, Jia Liu, Minmin Shi, Jun Zhang, Ting Wang and Baiyong Shen
    Citation: Cancer Cell International 2024 24:177
  28. Hepatocellular carcinoma (HCC) represents one of the most significant causes of mortality due to cancer-related deaths. It has been previously reported that the TGF-β signaling pathway may be associated with t...

    Authors: Jiong Li, Wendi Wang, Sang Li, Zhengkang Qiao, Haoyue Jiang, Xinyue Chang, Yaning Zhu, Hongpei Tan, Xiaoqian Ma, Yuqian Dong, Zhenhu He, Zhen Wang, Qin Liu, Shanhu Yao, Cejun Yang, Min Yang…
    Citation: Cancer Cell International 2024 24:176
  29. The incidence and mortality of lung cancer is the highest in China and the world. Brain is the most common distant metastasis site of lung cancer. Its transfer mechanism and predictive biomarkers are still unc...

    Authors: Hanjun Wang, Ling Wang, Sheng Zhang, Qicai Liu and Feng Gao
    Citation: Cancer Cell International 2024 24:175
  30. Acute myeloid leukemia (AML) is a complex hematologic malignancy characterized by uncontrolled proliferation of myeloid precursor cells within bone marrow. Despite advances in understanding of its molecular un...

    Authors: Namsoo Kim, Seungmin Hahn, Yu Jeong Choi, Hyunsoo Cho, Haerim Chung, Ji Eun Jang, Chuhl Joo Lyu, Seung-Tae Lee, Jong Rak Choi, June-Won Cheong and Saeam Shin
    Citation: Cancer Cell International 2024 24:174
  31. Drug resistance poses a significant challenge in cancer treatment, particularly as a leading cause of therapy failure. Cisplatin, the primary drug for lung adenocarcinoma (LUAD) chemotherapy, shows effective t...

    Authors: Xiaomin Mao, Shumin Xu, Huan Wang, Peng Xiao, Shumin Li, Jiaji Wu, Junhui Sun, Cheng Jin, Mo Shen, Yueli Shi, Bufu Tang, Ying Yang, Weiyu Chen, Zhiyong Xu and Yun Xu
    Citation: Cancer Cell International 2024 24:173
  32. Cervical cancer is a human papillomavirus (HPV)-related disease. HPV type 16 (HPV16), which is the predominant cause of cervical cancer, can encode miRNAs (HPV16-miRNAs). However, the role of HPV16-miRNAs in t...

    Authors: Yunuan Wang, Xueying Wang, Yiting Liu, Yuxin He, Xiaoling Duan, Qinmei Li, Yanchun Huang, Guoxiong Xu and Qi Lu
    Citation: Cancer Cell International 2024 24:172
  33. As a highly heterogeneous tumor, non-small cell lung cancer (NSCLC) is famous for its high incidence and mortality worldwide. Smoking can cause genetic changes, which leading to the occurrence and progress of ...

    Authors: Qixuan Li, Tianyi Wang, Yijie Tang, Xian Zou, Zhongqi Shen, Zixin Tang, Youlang Zhou and Jiahai Shi
    Citation: Cancer Cell International 2024 24:171
  34. Mousedouble minute 2 (MDM2) is one of the molecules activated by p53 and plays an important role in the regulation of p53. MDM2 is generally believed to function as a negative regulator of p53 by facilitating ...

    Authors: Yumei Yao, Qian Zhang, Zhi Li and Hushan Zhang
    Citation: Cancer Cell International 2024 24:170
  35. Forkhead box E1 (FOXE1), also known as thyroid transcription factor 2 (TTF-2), belongs to a large family of forkhead transcription factors. It plays important roles in embryogenesis, cell growth, and differentiat...

    Authors: Qinlan Shi, Zhongting Huang, Yeye Kuang, Chan Wang, Xiao Fang and Xiaotong Hu
    Citation: Cancer Cell International 2024 24:169
  36. “Disulfide death,” a form of cellular demise, is triggered by the abnormal accumulation of intracellular disulfides under conditions of glucose deprivation. However, its role in the prognosis of glioma remains...

    Authors: HaoYuan Wu, ZhiHao Yang, ChenXi Chang, ZhiWei Wang, DeRan Zhang, QingGuo Guo and Bing Zhao
    Citation: Cancer Cell International 2024 24:168
  37. Accumulating evidences indicate that the specific alternative splicing (AS) events are linked to the occurrence and prognosis of gastric cancer (GC). Nevertheless, the impact of AS is still unclear and needed ...

    Authors: Nan Zhu, Yupeng Zhao, Wenjing Yan, Lan Wei, Qingqing Sang, Jianfang Li, Bingya Liu and Beiqin Yu
    Citation: Cancer Cell International 2024 24:167
  38. Triple-negative breast cancer (TNBC) is highly malignant and lacks effective biotherapeutic targets. The development of efficient anticancer drugs with low toxicity and few side effects is a hotspot in TNBC tr...

    Authors: Ming Li, Shiyao Kang, Xuming Deng, Huimin Li, Yuan Zhao, Wenru Tang and Miaomiao Sheng
    Citation: Cancer Cell International 2024 24:166
  39. Kidney Clear Cell Carcinoma (KIRC), the predominant form of kidney cancer, exhibits a diverse therapeutic response to Immune Checkpoint Inhibitors (ICIs), highlighting the need for predictive models of ICI eff...

    Authors: Qingshui Wang, Jiamin Liu, Ruiqiong Li, Simeng Wang, Yining Xu, Yawen Wang, Hao Zhang, Yingying Zhou, Xiuli Zhang, Xuequn Chen, Wei Zhuang and Yao Lin
    Citation: Cancer Cell International 2024 24:164
  40. Esophageal squamous cell carcinoma (ESCC) is one of most prevalent cancers worldwide, especially in China. Lacking in depth mechanism study, effective targets and therapeutics are desperately needed in the cli...

    Authors: Yuan Li, Zhuya Xiao, Yingying Wang, Daoming Zhang and Zuhua Chen
    Citation: Cancer Cell International 2024 24:162

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