Skip to main content


Page 1 of 77

  1. Immune checkpoint inhibitors are approved for the treatment of various tumors, but the response rate is not satisfactory in certain malignancies. Inhibitor of apoptosis proteins (IAP) ubiquitin-E3 ligase activ...

    Authors: Wentao Pan, Qiuyun Luo, Eric Liang, Mude Shi, Jian Sun, Huimin Shen, Zhenhai Lu, Lin Zhang, Xianglei Yan, Luping Yuan, Suna Zhou, Hanjie Yi, Yifan Zhai, Miao-zhen Qiu and Dajun Yang
    Citation: Cancer Cell International 2024 24:181
  2. Although rare, uveal melanoma (UM) is a life-threatening malignancy. Understanding its biology is necessary to improve disease outcome. Three-dimensional (3D) in vitro culture methods have emerged as tools tha...

    Authors: Alicia A. Goyeneche, Jade M. E. Lasiste, Mohamed Abdouh, Prisca Bustamante, Julia V. Burnier and Miguel N. Burnier Jr.
    Citation: Cancer Cell International 2024 24:180
  3. Radiotherapy (RT) has been identified as a vital treatment for esophageal squamous cell carcinoma (ESCC), while the development of radioresistance remains a major obstacle in ESCC management. The aim of this s...

    Authors: Dong Guo, Shuo Zhou, Ruixue Liu, Weinan Yao, Shuguang Li, Xueyuan Zhang, Wenbin Shen and Shuchai Zhu
    Citation: Cancer Cell International 2024 24:179
  4. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors worldwide, with extremely aggressive and complicated biology. Krüppel-like factors (KLFs) encode a series of transcriptional regulatory pr...

    Authors: Jiayu Lin, Pengyi Liu, Keyan Sun, Lingxi Jiang, Yang Liu, Yishu Huang, Jia Liu, Minmin Shi, Jun Zhang, Ting Wang and Baiyong Shen
    Citation: Cancer Cell International 2024 24:177
  5. Hepatocellular carcinoma (HCC) represents one of the most significant causes of mortality due to cancer-related deaths. It has been previously reported that the TGF-β signaling pathway may be associated with t...

    Authors: Jiong Li, Wendi Wang, Sang Li, Zhengkang Qiao, Haoyue Jiang, Xinyue Chang, Yaning Zhu, Hongpei Tan, Xiaoqian Ma, Yuqian Dong, Zhenhu He, Zhen Wang, Qin Liu, Shanhu Yao, Cejun Yang, Min Yang…
    Citation: Cancer Cell International 2024 24:176
  6. The incidence and mortality of lung cancer is the highest in China and the world. Brain is the most common distant metastasis site of lung cancer. Its transfer mechanism and predictive biomarkers are still unc...

    Authors: Hanjun Wang, Ling Wang, Sheng Zhang, Qicai Liu and Feng Gao
    Citation: Cancer Cell International 2024 24:175
  7. Acute myeloid leukemia (AML) is a complex hematologic malignancy characterized by uncontrolled proliferation of myeloid precursor cells within bone marrow. Despite advances in understanding of its molecular un...

    Authors: Namsoo Kim, Seungmin Hahn, Yu Jeong Choi, Hyunsoo Cho, Haerim Chung, Ji Eun Jang, Chuhl Joo Lyu, Seung-Tae Lee, Jong Rak Choi, June-Won Cheong and Saeam Shin
    Citation: Cancer Cell International 2024 24:174
  8. Drug resistance poses a significant challenge in cancer treatment, particularly as a leading cause of therapy failure. Cisplatin, the primary drug for lung adenocarcinoma (LUAD) chemotherapy, shows effective t...

    Authors: Xiaomin Mao, Shumin Xu, Huan Wang, Peng Xiao, Shumin Li, Jiaji Wu, Junhui Sun, Cheng Jin, Mo Shen, Yueli Shi, Bufu Tang, Ying Yang, Weiyu Chen, Zhiyong Xu and Yun Xu
    Citation: Cancer Cell International 2024 24:173
  9. Cervical cancer is a human papillomavirus (HPV)-related disease. HPV type 16 (HPV16), which is the predominant cause of cervical cancer, can encode miRNAs (HPV16-miRNAs). However, the role of HPV16-miRNAs in t...

    Authors: Yunuan Wang, Xueying Wang, Yiting Liu, Yuxin He, Xiaoling Duan, Qinmei Li, Yanchun Huang, Guoxiong Xu and Qi Lu
    Citation: Cancer Cell International 2024 24:172
  10. As a highly heterogeneous tumor, non-small cell lung cancer (NSCLC) is famous for its high incidence and mortality worldwide. Smoking can cause genetic changes, which leading to the occurrence and progress of ...

    Authors: Qixuan Li, Tianyi Wang, Yijie Tang, Xian Zou, Zhongqi Shen, Zixin Tang, Youlang Zhou and Jiahai Shi
    Citation: Cancer Cell International 2024 24:171
  11. Mousedouble minute 2 (MDM2) is one of the molecules activated by p53 and plays an important role in the regulation of p53. MDM2 is generally believed to function as a negative regulator of p53 by facilitating ...

    Authors: Yumei Yao, Qian Zhang, Zhi Li and Hushan Zhang
    Citation: Cancer Cell International 2024 24:170
  12. Forkhead box E1 (FOXE1), also known as thyroid transcription factor 2 (TTF-2), belongs to a large family of forkhead transcription factors. It plays important roles in embryogenesis, cell growth, and differentiat...

    Authors: Qinlan Shi, Zhongting Huang, Yeye Kuang, Chan Wang, Xiao Fang and Xiaotong Hu
    Citation: Cancer Cell International 2024 24:169
  13. “Disulfide death,” a form of cellular demise, is triggered by the abnormal accumulation of intracellular disulfides under conditions of glucose deprivation. However, its role in the prognosis of glioma remains...

    Authors: HaoYuan Wu, ZhiHao Yang, ChenXi Chang, ZhiWei Wang, DeRan Zhang, QingGuo Guo and Bing Zhao
    Citation: Cancer Cell International 2024 24:168
  14. Accumulating evidences indicate that the specific alternative splicing (AS) events are linked to the occurrence and prognosis of gastric cancer (GC). Nevertheless, the impact of AS is still unclear and needed ...

    Authors: Nan Zhu, Yupeng Zhao, Wenjing Yan, Lan Wei, Qingqing Sang, Jianfang Li, Bingya Liu and Beiqin Yu
    Citation: Cancer Cell International 2024 24:167
  15. Triple-negative breast cancer (TNBC) is highly malignant and lacks effective biotherapeutic targets. The development of efficient anticancer drugs with low toxicity and few side effects is a hotspot in TNBC tr...

    Authors: Ming Li, Shiyao Kang, Xuming Deng, Huimin Li, Yuan Zhao, Wenru Tang and Miaomiao Sheng
    Citation: Cancer Cell International 2024 24:166
  16. Kidney Clear Cell Carcinoma (KIRC), the predominant form of kidney cancer, exhibits a diverse therapeutic response to Immune Checkpoint Inhibitors (ICIs), highlighting the need for predictive models of ICI eff...

    Authors: Qingshui Wang, Jiamin Liu, Ruiqiong Li, Simeng Wang, Yining Xu, Yawen Wang, Hao Zhang, Yingying Zhou, Xiuli Zhang, Xuequn Chen, Wei Zhuang and Yao Lin
    Citation: Cancer Cell International 2024 24:164
  17. Esophageal squamous cell carcinoma (ESCC) is one of most prevalent cancers worldwide, especially in China. Lacking in depth mechanism study, effective targets and therapeutics are desperately needed in the cli...

    Authors: Yuan Li, Zhuya Xiao, Yingying Wang, Daoming Zhang and Zuhua Chen
    Citation: Cancer Cell International 2024 24:162
  18. PD-L1 intrinsically promotes tumor progression through multiple mechanisms, which potentially leads to resistance to anti-PD-1/PD-L1 therapies. The intrinsic effect of PD-L1 on breast cancer (BC) cell prolifer...

    Authors: Marwa Elfoly, Jumanah Y. Mirza, Ayodele Alaiya, Amal A. Al-Hazzani, Asma Tulbah, Monther Al-Alwan and Hazem Ghebeh
    Citation: Cancer Cell International 2024 24:161
  19. In recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic and therapeutic appr...

    Authors: Habib Ghaznavi, Reza Afzalipour, Samideh Khoei, Saman Sargazi, Sakine Shirvalilou and Roghayeh Sheervalilou
    Citation: Cancer Cell International 2024 24:160
  20. Single nuclear polymorphisms (SNPs) have been published to be correlated with multiple diseases. Transcription Factor 21 (TCF21) is a critical transcription factor involved in various types of cancers. However...

    Authors: Xinyi Zhou, Kuan Shen, Shuqing Cao, Pengyu Li, Jian Xiao, Jiacheng Dong, Quan Cheng, Li Hu, Zekuan Xu and Li Yang
    Citation: Cancer Cell International 2024 24:159
  21. Over the past decade, heat shock protein 90 (HSP90) inhibitors have emerged as promising anticancer drugs in solid and hematological malignancies. Flavokawain C (FKC) is a naturally occurring chalcone that has...

    Authors: YuQiang Hu, ChenJie Yu, LiangJun Cheng, Chang Zhong, Jun An, MingZhen Zou, Bing Liu and Xia Gao
    Citation: Cancer Cell International 2024 24:158
  22. Identifying molecular biomarkers for predicting responses to anti-cancer drugs can enhance treatment precision and minimize side effects. This study investigated the novel cancer-targeting mechanism of combini...

    Authors: Yu-Jeong Choi, Kangwook Lee, Seo Yeon Lee, Youngbin Kwon, Jaehyuk Woo, Chan-Yong Jeon and Seong-Gyu Ko
    Citation: Cancer Cell International 2024 24:156
  23. The exosome-mediated extracellular secretion of miRNAs occurs in many cancers, and RAB27A is a potent regulator of exosome secretion. For metastatic renal cell carcinoma (RCC), this study examines the mechanis...

    Authors: Dae Hyun Song, Jong Sil Lee, Jeong-Hee Lee, Dong Chul Kim, Jung Wook Yang, Min Hye Kim, Ji Min Na, Hyun-kyung Cho, Jiyun Yoo and Hyo Jung An
    Citation: Cancer Cell International 2024 24:153
  24. Ovarian cancer (OC) is a malignancy among female globally. Circular RNAs (circRNAs) are a family of circular endogenous RNAs generated from selective splicing, which take part in many traits. Former investigat...

    Authors: Zhongxin Yan, Changling Duan, Xi Li, Hao Wang, Shanji Li, Xuexin Zhou and Yi Miao
    Citation: Cancer Cell International 2024 24:152
  25. The purinergic P2X7 receptor (P2X7R) plays an important role in the crosstalk between pancreatic stellate cells (PSCs) and cancer cells, thus promoting progression of pancreatic ductal adenocarcinoma (PDAC). S...

    Authors: Lara Magni, Haoran Yu, Nynne M. Christensen, Mette H. Poulsen, Alexander Frueh, Ganga Deshar, Astrid Z. Johansen, Julia S. Johansen, Stephan A. Pless, Niklas R. Jørgensen and Ivana Novak
    Citation: Cancer Cell International 2024 24:148
  26. Colon cancer ranks third among global tumours and second in cancer-related mortality, prompting an urgent need to explore new therapeutic targets. C6orf15 is a novel gene that has been reported only in Sjogren...

    Authors: Jiankang Yu, Jian Sun, Jingtong Tang, Jiayu Xu, Guanru Qian and Jianping Zhou
    Citation: Cancer Cell International 2024 24:146
  27. Lung adenocarcinoma is a major public health problem with the low 5-year survival rate (15%) among cancers. Aberrant alterations of meiotic genes, which have gained increased attention recently, might contribu...

    Authors: Yating Liu, Lianlian Ouyang, Shiyao Jiang, Lu Liang, Yuanbing Chen, Chao Mao, Yiqun Jiang and Li Cong
    Citation: Cancer Cell International 2024 24:145
  28. Breast cancer is the most common cancer in women worldwide. Toxoplasma gondii (T. gondii) has shown anticancer activity in breast cancer mouse models, and exerted beneficial effect on the survival of breast cance...

    Authors: Hengming Ye, Xiaotao Zhou, Bike Zhu, Tiantian Xiong, Weile Huang, Feng He, Hui Li, Lihua Chen, Luying Tang and Zefang Ren
    Citation: Cancer Cell International 2024 24:144
  29. Hepatocellular carcinoma (HCC) is widely recognized for its unfavorable prognosis. Increasing evidence has revealed that LGALS3 has an essential function in initiating and developing several malignancies in hu...

    Authors: Yinghui Ren, Yongmei Qian, Qicheng Zhang, Xiaoping Li, Mingjiang Li, Wei Li, Pan Yang, Hengchang Ren, Hongxia Li, Yiqi Weng, Dengwen Li, Ke Xu and Wenli Yu
    Citation: Cancer Cell International 2024 24:142
  30. Prompt identification and assessment of the disease are essential for reducing the death rate associated with colorectal cancer (COL). Identifying specific causal or sensitive components, such as coding RNA (c...

    Authors: Navid Abedpoor, Farzaneh Taghian, Khosro Jalali Dehkordi and Kamran Safavi
    Citation: Cancer Cell International 2024 24:141
  31. The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is crucial for enhancing cellula...

    Authors: Chia-Jung Li, Yen-Dun Tony Tzeng, Jui-Hu Hsiao, Ling-Ming Tseng, Tzu-Sheng Hsu and Pei-Yi Chu
    Citation: Cancer Cell International 2024 24:140
  32. Immunogenic cell death (ICD) is closely related to anti-tumor therapy and regulates the tumor microenvironment (TME). This study aims to explore the molecular characteristics of ICD in acute myeloid leukemia (...

    Authors: Fangmin Zhong, Shuyang He, Ni Guo, Luyi Shi, Linlin Zhang, Hua Jin and Guangyao Kong
    Citation: Cancer Cell International 2024 24:139
  33. N6-methyladenosine (m6A) is important in regulating mRNA stability, splicing, and translation, and it also contributes to tumor development. However, there is still limited understanding of the comprehensive e...

    Authors: Yunxing Shi, Kai Li, Yichuan Yuan, Chenwei Wang, Zhiwen Yang, Dinglan Zuo, Yi Niu, Jiliang Qiu, Binkui Li, Yunfei Yuan and Wei He
    Citation: Cancer Cell International 2024 24:138
  34. Exosomes derived from tumor cells contribute to the pathogenesis of cancers. Metformin, the most usually used drug for type 2 diabetes, has been frequently investigated for anticancer effects. Here, we examine...

    Authors: Reza Abbasi, Vahid Nejati and Jafar Rezaie
    Citation: Cancer Cell International 2024 24:137
  35. Hydrogen sulfide (H2S) is a significant endogenous mediator that has been implicated in the progression of various forms of cancer including breast cancer (BC). Cystathionine-β-synthase (CBS), cystathionine-γ-lya...

    Authors: Alyaa Dawoud, Rana A. Youness, Heba Nafea, Tamer Manie, Carole Bourquin, Csaba Szabo, Reham M. Abdel-Kader and Mohamed Z. Gad
    Citation: Cancer Cell International 2024 24:136
  36. One of the contributing factors in the diagnosis and treatment of most cancers is the identification of their surface antigens. Cancer tissues or cells have their specific antigens. Some antigens that are pres...

    Authors: Tina Nayerpour Dizaj, Abolfazl Doustmihan, Behnaz Sadeghzadeh Oskouei, Morteza Akbari, Mehdi Jaymand, MirAhmad Mazloomi and Rana Jahanban-Esfahlan
    Citation: Cancer Cell International 2024 24:135
  37. Some noncoding RNAs (ncRNAs) carry open reading frames (ORFs) that can be translated into micropeptides, although noncoding RNAs (ncRNAs) have been previously assumed to constitute a class of RNA transcripts w...

    Authors: He Zhou, Yan Wu, Ji Cai, Dan Zhang, Dongfeng Lan, Xiaofang Dai, Songpo Liu, Tao Song, Xianyao Wang, Qinghong Kong, Zhixu He, Jun Tan and Jidong Zhang
    Citation: Cancer Cell International 2024 24:134

Annual Journal Metrics

  • 2022 Citation Impact
    5.8 - 2-year Impact Factor
    5.6 - 5-year Impact Factor
    0.994 - SNIP (Source Normalized Impact per Paper)
    1.145 - SJR (SCImago Journal Rank)

    2023 Speed
    34 days submission to first editorial decision for all manuscripts (Median)
    110 days submission to accept (Median)

    2023 Usage 
    1,052 Altmetric mentions 

Institutional membership

Visit the membership page to check if your institution is a member and learn how you could save on article-processing charges (APCs).

Funding your APC

​​​​​​​Open access funding and policy support by SpringerOpen​​

​​​​We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here