Skip to main content

Articles

Page 1 of 75

  1. Acute myeloid leukemia (AML) is a malignancy of the hematopoietic system, and childhood AML accounts for about 20% of pediatric leukemia. ANP32B, an important nuclear protein associated with proliferation, has...

    Authors: Xiaomei Wan, Jianwei Wang, Fang Fang, Yixin Hu, Zimu Zhang, Yanfang Tao, Yongping Zhang, Juanjuan Yu, Yumeng Wu, Bi Zhou, Hongli Yin, Li Ma, Xiaolu Li, Ran Zhuo, Wei Cheng, Shuqi Zhang…
    Citation: Cancer Cell International 2024 24:81
  2. Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) still present a huge threaten to women’s health, especially the local advanced patients. Hence, developing more effectiveness prognostic ...

    Authors: Xiaomei Chen, Xunhu Dong, Hong Li, Tingting Wu, Haoyin Liu, Jie Wu, Wei Ge, Lingji Hao and Zhe Zhang
    Citation: Cancer Cell International 2024 24:80
  3. Hepatocellular carcinoma (HCC) cells usually show strong resistance to chemotherapy, which not only reduces the efficacy of chemotherapy but also increases the side effects. Regulation of autophagy plays an im...

    Authors: Lili Sun, Yaru Li, Renshuang Zhao, Qinlei Fan, Fei Liu, Yilong Zhu, Jicheng Han, Yunyun Liu, Ningyi Jin, Xiao Li and Yiquan Li
    Citation: Cancer Cell International 2024 24:79
  4. Liver specific genes (LSGs) are crucial for hepatocyte differentiation and maintaining normal liver function. A deep understanding of LSGs and their heterogeneity in hepatocellular carcinoma (HCC) is necessary...

    Authors: Xiuzhi Zhang, Zhefeng Xiao, Xia Zhang, Ningning Li, Tao Sun, JinZhong Zhang, Chunyan Kang, Shasha Fan, Liping Dai and Xiaoli liu
    Citation: Cancer Cell International 2024 24:78
  5. Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid peroxidation. Its role in cancer metastasis remains unclear. In this study, we aimed to investigate the potential involvement...

    Authors: Juan Sun, Jie Li, Kostas Pantopoulos, Yuqin Liu, Yixuan He, Weiming Kang and Xin Ye
    Citation: Cancer Cell International 2024 24:77
  6. To examine the role of RhoB expression in relation to chemotherapy response, clinical outcomes and associated signaling pathways in colorectal cancer patients.

    Authors: Maria Kopsida, Na Liu, Angeliki Kotti, Jing Wang, Lasse Jensen, Ganesan Jothimani, Camilla Hildesjo, Staffan Haapaniemi, Wen Zhong, Surajit Pathak and Xiao-Feng Sun
    Citation: Cancer Cell International 2024 24:75
  7. Breast cancer is the most prevalent female tumor, of which triple-negative breast cancer (TNBC) accounts for about 15%. Characterized by its aggressive nature and limited treatment options, TNBC currently stan...

    Authors: Mei Zhao, Panling Xu, Wenjing Shi, Juan Wang, Ting Wang and Ping Li
    Citation: Cancer Cell International 2024 24:74
  8. Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays an important role in diverse cellular processes by regulating Rho guanosine triphosphate (GTP)ases activity. RhoGDI1 phosphorylation regulates th...

    Authors: Jeewon Lim, Yo Sep Hwang, Hyang Ran Yoon, Jiyun Yoo, Suk Ran Yoon, Haiyoung Jung, Hee Jun Cho and Hee Gu Lee
    Citation: Cancer Cell International 2024 24:73
  9. Glioblastoma (GBM) is the most lethal primary brain tumor in adult, characterized by highly aggressive and infiltrative growth. The current therapeutic management of GBM includes surgical resection followed by...

    Authors: Giorgia Castellani, Mariachiara Buccarelli, Quintino Giorgio D’Alessandris, Ramona Ilari, Andrea Cappannini, Francesca Pedini, Alessandra Boe, Valentina Lulli, Isabella Parolini, Stefano Giannetti, Mauro Biffoni, Vincenzo Zappavigna, Giovanna Marziali, Roberto Pallini and Lucia Ricci-Vitiani
    Citation: Cancer Cell International 2024 24:72
  10. Gastric cancer (GC) stands as a prevalent and deadly global malignancy. Despite its role as a preoperative neoadjuvant therapy, Apatinib’s effectiveness is curtailed among GC patients exhibiting elevated YY1 e...

    Authors: Zi-Han Geng, Jun-Xian Du, Yue-Da Chen, Pei-Yao Fu, Ping-Hong Zhou, Wen-Zheng Qin and Yi-Hong Luo
    Citation: Cancer Cell International 2024 24:71
  11. Glioblastoma (GBM) is the most common brain tumor with the worst prognosis. Temozolomide is the only first-line drug for GBM. Unfortunately, the resistance issue is a classic problem. Therefore, it is essentia...

    Authors: Yizhi Zhang, Wan Li, Yihui Yang, Sen Zhang, Hong Yang, Yue Hao, Xu Fang, Guanhua Du, Jianyou Shi, Lianqiu Wu and Jinhua Wang
    Citation: Cancer Cell International 2024 24:69
  12. Cuproptosis-related genes (CRGs) are associated with lung adenocarcinoma. However, the links between CRGs and non-small-cell lung cancer (NSCLC) are not clear. In this study, we aimed to develop two cuproptosi...

    Authors: Yijie Tang, Tianyi Wang, Qixuan Li and Jiahai Shi
    Citation: Cancer Cell International 2024 24:68
  13. Targeted drug delivery is one of the attractive ways in which cancer treatment can significantly reduce side effects. In the last two decades, the use of antibodies as a tool for accurate detection of cancer h...

    Authors: Mohadeseh Haji Abdolvahab, Pegah Karimi, Nasrin Mohajeri, Mohammad Abedini and Hamed Zare
    Citation: Cancer Cell International 2024 24:67
  14. Acute myeloid leukemia (AML) is a malignant hematologic disease caused by gene mutations and genomic rearrangements in hematologic progenitors. The PHF6 (PHD finger protein 6) gene is highly conserved and loca...

    Authors: Shengnan Yuan, Mingming Gao, Yizhou Wang, Yanjie Lan, Mengrou Li, Yuwei Du, Yue Li, Wen Ju, Yujin Huang, Ke Yuan and Lingyu Zeng
    Citation: Cancer Cell International 2024 24:66
  15. Pediatric T-cell acute lymphoblastic leukemia (T-ALL) poses significant challenges due to its aggressive nature and resistance to standard treatments. Long non-coding RNAs (lncRNAs) have emerged as potential b...

    Authors: Pankaj Sharma, Parminder kaur, Prateek Bhatia, Amita Trehan, Sreejesh Sreedharanunni and Minu Singh
    Citation: Cancer Cell International 2024 24:65
  16. Esophageal cancer (EC) is a global canker notorious for causing high mortality due to its relentless incidence rate, convoluted with unyielding recurrence and metastasis. However, these intricacies of EC are a...

    Authors: Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang…
    Citation: Cancer Cell International 2024 24:64
  17. The incidence of melanoma, the most lethal form of skin cancer, has increased due to ultraviolet exposure. The treatment of advanced melanoma, particularly metastatic cases, remains challenging with poor outco...

    Authors: Ming-yun Hsieh, Sheng-Kai Hsu, Tzu-Yu Liu, Chang-Yi Wu and Chien-Chih Chiu
    Citation: Cancer Cell International 2024 24:63
  18. m6A modification has close connection with the occurrence, development, and prognosis of tumors. This study aimed to explore the roles of m6A modification and its related mechanisms in non-small cell lung canc...

    Authors: Xianxiu Ji, Xiaoying Wan, Hui Sun, Qinfang Deng, Shuyan Meng, Boxiong Xie and Songwen Zhou
    Citation: Cancer Cell International 2024 24:61
  19. Glioblastoma (GBM) characterized by immune escape is the most malignant primary brain tumors, which has strong immunosuppressive effect. Programmed death ligand-1 (PD-L1) is a recognized immunosuppressive memb...

    Authors: Leilei Zhao, Yudi Wang, Peizheng Mu, Xuehua Zhang, Ruomei Qi, Yurui Zhang, He Zhang, Xiao Zhu, Zhouyan Dong and Yucui Dong
    Citation: Cancer Cell International 2024 24:60
  20. Peroxiredoxin 3 (PRDX3), a mitochondrial hydrogen peroxide scavenger, is known to be upregulated during tumorigenesis and cancer progression. In this study, we provide evidence for the first time that PRDX3 co...

    Authors: Pei-Jou Chua, Suet-Hui Ow, Cheng-Teng Ng, Wan-Hong Huang, Jie-Ting Low, Puay Hoon Tan, Michael W.Y. Chan and Boon-Huat Bay
    Citation: Cancer Cell International 2024 24:59
  21. Tongue squamous cell carcinoma (TSCC) is an aggressive oral cancer with a high incidence of metastasis and poor prognosis. We aim to identify and verify potential biomarkers for TSCC using bioinformatics analy...

    Authors: Huixin Dou, Can Song, Xiaoyan Wang, Zhien Feng, Yingying Su and Hao Wang
    Citation: Cancer Cell International 2024 24:58
  22. AlkB homolog 1, histone H2A dioxygenase (ALKBH1), a crucial enzyme involved in RNA demethylation in humans, plays a significant role in various cellular processes. While its role in tumor progression is well-e...

    Authors: Renin Chang, Kuan-Hao Tsui, Li-Fei Pan and Chia-Jung Li
    Citation: Cancer Cell International 2024 24:57
  23. About 30% of Prostate cancer (PCa) patients progress to metastatic PCa that remains largely incurable. This evidence underlines the need for the development of innovative therapies. In this direction, the pote...

    Authors: Valeria Pecci, Fabiola Troisi, Aurora Aiello, Sara De Martino, Angela Carlino, Vincenzo Fiorentino, Cristian Ripoli, Dante Rotili, Francesco Pierconti, Maurizio Martini, Manuela Porru, Francesco Pinto, Antonello Mai, Pier Francesco Bassi, Claudio Grassi, Carlo Gaetano…
    Citation: Cancer Cell International 2024 24:56
  24. Emerging data point to the critical role of snoRNA in the emergence of different types of cancer, but scarcely in breast cancer (BC). This study aimed to clarify the differential expressions and potential diag...

    Authors: Xiao Li, Xuan Zhao, Li Xie, Xingguo Song and Xianrang Song
    Citation: Cancer Cell International 2024 24:55
  25. Ovarian cancer (OC) has the highest mortality rate among all gynecological malignancies. A hypoxic microenvironment is a common feature of solid tumors, including ovarian cancer, and an important driving facto...

    Authors: Jiaqi Xu, Fei Wu, Yue Zhu, Tiantian Wu, Tianyue Cao, Wenxin Gao, Meng Liu, Weifeng Qian, Guannan Feng, Xiaoxue Xi and Shunyu Hou
    Citation: Cancer Cell International 2024 24:54
  26. Ovarian cancer (OV) is the most lethal gynecological malignancy worldwide, with high recurrence rates. Anoikis, a newly-acknowledged form of programmed cell death, plays an essential role in cancer progression...

    Authors: Jiani Yang, Yue Zhang, Shanshan Cheng, Yanna Xu, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu, Chao Wang and Yu Wang
    Citation: Cancer Cell International 2024 24:53
  27. A minute fraction of patients stands to derive substantial benefits from immunotherapy, primarily attributable to immune evasion. Our objective was to formulate a predictive signature rooted in genes associate...

    Authors: Xu Wang, Shixin Chan, Jiajie Chen, Yuanmin Xu, Longfei Dai, Qijun Han, Zhenglin Wang, Xiaomin Zuo, Yang Yang, Hu Zhao, Ming Wang, Chen Wang, Zichen Li, Huabing Zhang and Wei Chen
    Citation: Cancer Cell International 2024 24:52
  28. Engrailed homeobox 1 (EN1) is a candidate oncogene that is epigenetically modified in salivary adenoid cystic carcinoma (SACC). We investigated the expression of EN1 in SACC tissues and cells, EN1 promoter methyl...

    Authors: Yajuan Cui, Ye Zhang, Yuping Liu, Zheng Zhou, Lijing Zhu and Chuan-Xiang Zhou
    Citation: Cancer Cell International 2024 24:51
  29. Although a combination of immune checkpoint inhibitors (ICIs) is recommended as the first line treatment option for metastatic renal cell carcinoma (mRCC), several immune-related adverse events (irAEs) occur, ...

    Authors: Jee Soo Park, Myung Eun Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, Won Sik Jang and Won Sik Ham
    Citation: Cancer Cell International 2024 24:50
  30. Luminal breast cancer (BC) is a prevalent subtype associated with an increased risk of late disease recurrence and mortality. Long noncoding RNAs (lncRNAs) likely play significant roles in regulating tissue-sp...

    Authors: Yue Meng, Dianrong Zhou, Ying Luo, Jierong Chen and Hui Li
    Citation: Cancer Cell International 2024 24:49
  31. The diagnosis of T-cell lymphomas is typically established through a multiparameter approach that combines clinical, morphologic, immunophenotypic, and genetic features, utilizing a variety of histopathologic ...

    Authors: Muhammad Sufyan Bin Masroni, Gracie Wee Ling Eng, Ah-Jung Jeon, Yuan Gao, He Cheng, Sai Mun Leong, Jit Kong Cheong, Susan Swee-Shan Hue and Soo Yong Tan
    Citation: Cancer Cell International 2024 24:48
  32. Long noncoding RNAs (lncRNAs) are significant contributors to various human malignancies. The aberrant expression of lncRNA LINC00894 has been reported in various human malignancies. We aimed to illustrate the...

    Authors: Xiang Zhou, Lisha Chang, Qiaoqiao Liang, Rongjie Zhao, Yong Xiao, Zheng Xu and Leitao Yu
    Citation: Cancer Cell International 2024 24:47
  33. Recently, the presence of different nanoparticles (NPs) has developed targeting drug delivery in treatment of cancer cell. Targeted drug delivery systems using NPs have shown great promise in improving the eff...

    Authors: Akram Firouzi Amandi, Zahra Bahmanyar, Mehdi Dadashpour, Mehrnoosh Lak, Mohammad Natami, Yusuf Döğüş, Mahsa Alem and Omid Ali Adeli
    Citation: Cancer Cell International 2024 24:46
  34. Pyroptosis, an inflammatory form of programmed cell death, has been implicated in the pathogenesis and progression of several cancers. However, the significance of pyroptosis-related genes (PRGs) in papillary ...

    Authors: Fang Li, Rui Du, Jiedong Kou, Jingting Li, Le Zhou, Daqi Zhang, Yantao Fu, Gianlorenzo Dionigi, Simona Bertoli, Hui Sun and Nan Liang
    Citation: Cancer Cell International 2024 24:45
  35. Gastric cancer (GC) ranks fifth for morbidity and third for mortality worldwide. The N6-methyladenosine (m6A) mRNA methylation is crucial in cancer biology and progression. However, the relationship between m6A m...

    Authors: Zehua Wang, Chen Chen, Jiao Shu, Jiaoyu Ai, Yihan Liu, Haoyue Cao, Yongxu Jia and Yanru Qin
    Citation: Cancer Cell International 2024 24:44
  36. The FGF/FGFR signaling pathway plays a critical role in human cancers. We analyzed the anti-tumor effect of AZD4547, an inhibitor targeting the FGF/FGFR pathway, in epithelial ovarian cancer (EOC) and strategi...

    Authors: Yoo-Young Lee, Ji-Yoon Ryu, Young-Jae Cho, Ju-Yeon Choi, Jung-Joo Choi, Chel Hun Choi, Jason K. Sa, Jae Ryoung Hwang and Jeong-Won Lee
    Citation: Cancer Cell International 2024 24:43
  37. Circular RNAs (circRNAs) are involved in the regulation of progression and drug resistance in ovarian cancer (OC). In the present study, we aimed to explore the role of circRAD23B, a newly identified circRNA, ...

    Authors: Hui Wang, Yashuang Zhang, Huixian Miao, Ting Xu, Xianglin Nie and Wenjun Cheng
    Citation: Cancer Cell International 2024 24:42
  38. Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumour. Despite advancements in surgery, radiotherapy and chemotherapy, which have improved the prognosis of most patients, a subset of patie...

    Authors: Xinyue Guo, Licheng Xu, Luan Nie, Chenyu Zhang, Yaohui Liu, Rui Zhao, Jing Cao, Linli Tian and Ming Liu
    Citation: Cancer Cell International 2024 24:41
  39. Drug resistance remains a challenge in ovarian cancer. In addition to aberrant activation of relevant signaling pathways, the adaptive stress response is emerging as a new spotlight of drug resistance in cance...

    Authors: Nan Lin, Liankun Sun, Jiannan Chai, Hang Qi, Yuanxin Zhao, Jiaoyan Ma, Meihui Xia and Xiaoqing Hu
    Citation: Cancer Cell International 2024 24:38
  40. One of the key features of cancer is energy metabolic reprogramming which is tightly related to cancer proliferation, invasion, metastasis, and chemotherapy resistance. NcRNAs are a class of RNAs having no pro...

    Authors: Shizhen Li, Mingjing Peng, Shiming Tan, Linda Oyang, Jinguan Lin, Longzheng Xia, Jiewen Wang, Nayiyuan Wu, Xianjie Jiang, Qiu Peng, Yujuan Zhou and Qianjin Liao
    Citation: Cancer Cell International 2024 24:37
  41. Although meningioma is the most common primary brain tumor, treatments rely on surgery and radiotherapy, and recurrent meningiomas have no standard therapeutic options due to a lack of clinically relevant rese...

    Authors: Dokyeong Kim, Junseong Park, Hyeon-Chun Park, Songzi Zhang, Minyoung Park, Soon A. Park, Sug Hyung Lee, Youn Soo Lee, Jae-Sung Park, Sin-Soo Jeun, Yeun-Jun Chung and Stephen Ahn
    Citation: Cancer Cell International 2024 24:36
  42. It is well known that tumor-associated macrophages (TAMs) play essential roles in brain tumor resistance to chemotherapy. However, the detailed mechanisms of how TAMs are involved in brain tumor resistance are...

    Authors: Sheng-Yan Wu, Wen-Jui Yu, Ting-Yi Chien, Yu-An Ren, Chi-Shuo Chen and Chi-Shiun Chiang
    Citation: Cancer Cell International 2024 24:35
  43. Male patients with papillary thyroid carcinoma (PTC) tend to have poorer prognosis compared to females, partially attributable to a higher rate of lymph node metastasis (LNM). Developing a precise predictive m...

    Authors: Jianlin Zhang, Xumin Zhou, Fan Yao, JiaLi Zhang and Qiang Li
    Citation: Cancer Cell International 2024 24:34
  44. Gastric cancer is a highly prevalent cancer type and the underlying molecular mechanisms are not fully understood. Ubiquitin-specific peptidase (USP) 29 has been suggested to regulate cell fate in several type...

    Authors: Rongfu Tu, Ye Kang, Yiwen Pan, Yanyan Da, Doudou Ren, Ru Zhang, Zeqiong Cai, Yijia Liu, Jiao Xu, Junpeng Ma, Zhiyong Zhou, Shupeng Yin, Xiaozhuang Li, Peng Zhang, Qi Zhang, Jingchao Wang…
    Citation: Cancer Cell International 2024 24:33

Annual Journal Metrics

  • 2022 Citation Impact
    5.8 - 2-year Impact Factor
    5.6 - 5-year Impact Factor
    0.994 - SNIP (Source Normalized Impact per Paper)
    1.145 - SJR (SCImago Journal Rank)

    2022 Speed
    13 days submission to first editorial decision for all manuscripts (Median)
    116 days submission to accept (Median)

    2022 Usage 
    2,208,493 downloads
    1,520 Altmetric mentions 

Institutional membership

Visit the membership page to check if your institution is a member and learn how you could save on article-processing charges (APCs).

Funding your APC

​​​​​​​Open access funding and policy support by SpringerOpen​​

​​​​We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here