Sort by
Previous Page Page 1 of 38 Next Page
  1. Primary Research

    The role of REST and HDAC2 in epigenetic dysregulation of Nav1.5 and nNav1.5 expression in breast cancer

    Increased expression of voltage-gated sodium channels (VGSCs) have been implicated with strong metastatic potential of human breast cancer in vitro and in vivo where the main culprits are cardiac isoform Nav1....

    Nur Sabrina Kamarulzaman, Hemaniswarri Dewi Dewadas, Chiuan Yee Leow, Nik Soriani Yaacob and Noor Fatmawati Mokhtar

    Cancer Cell International 2017 17:74

    Published on: 1 August 2017

  2. Research

    Pleomorphism and drug resistant cancer stem cells are characteristic of aggressive primary meningioma cell lines

    Meningioma tumors arise in arachnoid membranes, and are the most reported central nervous system (CNS) tumors worldwide. Up to 20% of grade I meningioma tumors reoccur and currently predictive cancer stem cell...

    Ishaq Khan, Saleh Baeesa, Mohammed Bangash, Hans-Juergen Schulten, Fahad Alghamdi, Hanadi Qashqari, Nawal Madkhali, Angel Carracedo, Mohamad Saka, Awatif Jamal, Jaudah Al-Maghrabi, Mohammed AlQahtani, Saleh Al-Karim, Ghazi Damanhouri, Kulvinder Saini, Adeel Chaudhary…

    Cancer Cell International 2017 17:72

    Published on: 21 July 2017

  3. Primary Research

    EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP

    Rituximab combined with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) is used as standard frontline regimen for diffuse large B-cell lymphoma (DLBCL). The landscape of somatic mutations in D...

    Jiao Li, Ning Ding, Xiaogan Wang, Lan Mi, Lingyan Ping, Xuan Jin, Yalu Liu, Zhitao Ying, Yan Xie, Weiping Liu, Yuqin Song and Jun Zhu

    Cancer Cell International 2017 17:70

    Published on: 14 July 2017

  4. Review

    Chemotherapy and tumor microenvironment of pancreatic cancer

    Pancreatic cancer is an extremely dismal malignance. Chemotherapy has been widely applied to treat this intractable tumor. It has exclusive tumor microenvironment (TME), characterized by dense desmoplasia and ...

    Qiaofei Liu, Quan Liao and Yupei Zhao

    Cancer Cell International 2017 17:68

    Published on: 5 July 2017

  5. Primary Research

    Induction of apoptosis and proliferation inhibition of hepatocellular carcinoma by 6-chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA): in vitro and vivo studies

    6-Chloro-2-methoxy-N-(phenylmethyl)-9-acridinamine (BA), a novel sponge-derived compound, has been reported to elicit a cytotoxic effect by inhibiting cell proliferation.

    Yun Huang, Guohua Liu, Feng Yang, Xiaowei Xing, Ying Li, Zhijun Huang and Hong Yuan

    Cancer Cell International 2017 17:66

    Published on: 3 July 2017

  6. Review

    HOTAIR: a key regulator in gynecologic cancers

    Long non-coding RNAs (lncRNAs) play critical roles in the initiation and progression of human cancers. HOX transcript antisense RNA (HOTAIR) is an lncRNA localized to the mammalian HOXC gene cluster; it can inter...

    Jing Li, Jing Wang, Yan Zhong, Ruixia Guo, Danxia Chu, Haifeng Qiu and Zhongfu Yuan

    Cancer Cell International 2017 17:65

    Published on: 21 June 2017

  7. Primary Research

    Overexpression of lncRNA HOXA11-AS promotes cell epithelial–mesenchymal transition by repressing miR-200b in non-small cell lung cancer

    Recent studies have verified that long noncoding RNAs (lncRNAs) involved in many biological functions and play crucial roles in human cancers progression, the study aimed to detect the association between long...

    Jian-Hui Chen, Li-Yang Zhou, Suo Xu, Yu-Long Zheng, Yu-Feng Wan and Cheng-Ping Hu

    Cancer Cell International 2017 17:64

    Published on: 12 June 2017

  8. Primary Research

    Suppression of endothelial cell migration by tumor associated macrophage-derived exosomes is reversed by epithelial ovarian cancer exosomal lncRNA

    To study the mechanism by which epithelial ovarian cancer (EOC)-derived exosomes restore the migration of endothelial cells that is suppressed by TAM-derived exosomes.

    Quanfeng Wu, Xiaoli Wu, Xiang Ying, Qinyi Zhu, Xinjing Wang, Lu Jiang, Xin Chen, Yueqian Wu and Xipeng Wang

    Cancer Cell International 2017 17:62

    Published on: 6 June 2017

  9. Primary Research

    Berberine regulates the protein expression of multiple tumorigenesis-related genes in hepatocellular carcinoma cell lines

    Hepatocellular carcinoma (HCC) is the seventh most common malignancy and the third leading cause of cancer-related death worldwide with an extremely grim prognosis. Berberine (BBR) has been found to inhibit pr...

    Tung-Yueh Chuang, Hsiao-Li Wu, Jie Min, Michael Diamond, Ricardo Azziz and Yen-Hao Chen

    Cancer Cell International 2017 17:59

    Published on: 30 May 2017

  10. Research article

    DMD transcripts in CRL-2061 rhabdomyosarcoma cells show high levels of intron retention by intron-specific PCR amplification

    The DMD gene encoding dystrophin is mutated in Duchenne muscular dystrophy, a fatal progressive muscle wasting disease. DMD has also been shown to act as a tumor suppressor gene. Rhabdomyosarcoma (RMS) is a mesod...

    Emma Tabe Eko Niba, Ryo Yamanaka, Abdul Qawee Mahyoob Rani, Hiroyuki Awano, Masaaki Matsumoto, Hisahide Nishio and Masafumi Matsuo

    Cancer Cell International 2017 17:58

    Published on: 23 May 2017

  11. Review

    Pepsinogen C expression, regulation and its relationship with cancer

    Pepsinogen C (PGC) belongs to the aspartic protease family and is secreted by gastric chief cells. PGC could be activated to pepsin C and digests polypeptides and amino acids, but as a zymogen PGC’s functions ...

    Shixuan Shen, Jingyi Jiang and Yuan Yuan

    Cancer Cell International 2017 17:57

    Published on: 23 May 2017

  12. Primary Research

    Growth of MCF-7 breast cancer cells and efficacy of anti-angiogenic agents in a hydroxyethyl chitosan/glycidyl methacrylate hydrogel

    Breast cancer negatively affects women’s health worldwide. The tumour microenvironment plays a critical role in tumour initiation, proliferation, and metastasis. Cancer cells are traditionally grown in two-dim...

    Hejing Wang, Junmin Qian, Yaping Zhang, Weijun Xu, Juxiang Xiao and Aili Suo

    Cancer Cell International 2017 17:55

    Published on: 16 May 2017

  13. Primary Research

    Hypoxia and TGF-β1 induced PLOD2 expression improve the migration and invasion of cervical cancer cells by promoting epithelial-to-mesenchymal transition (EMT) and focal adhesion formation

    Intra-tumoral hypoxia and increases in extracellular level of transforming growth factor β1 (TGF-β1), which are common findings in cancer, are associated with an increased risk of metastasis and mortality. Mor...

    Feifei Xu, Jialu Zhang, Guolin Hu, Lei Liu and Weijiang Liang

    Cancer Cell International 2017 17:54

    Published on: 12 May 2017

  14. Primary Research

    The cholesterol metabolite 27-hydroxycholesterol stimulates cell proliferation via ERβ in prostate cancer cells

    For every six men, one will be diagnosed with prostate cancer (PCa) in their lifetime. Estrogen receptors (ERs) are known to play a role in prostate carcinogenesis. However, it is unclear whether the estrogeni...

    Shaneabbas Raza, Megan Meyer, Casey Goodyear, Kimberly D. P. Hammer, Bin Guo and Othman Ghribi

    Cancer Cell International 2017 17:52

    Published on: 11 May 2017

Previous Page Page 1 of 38 Next Page