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  1. Circular RNAs (circRNAs) belong to a class of covalently closed single stranded RNAs that have been implicated in cancer progression. Former investigations showed that hsa-circ-0013561 is abnormally expressed ...

    Authors: Kaisai Tian, Liying Zheng, Tailei Yuan, Xiaoping Chen, Qun Chen, Xiaocheng Xue, Shuixian Huang, Weining He, Mingming Jin and Yi Zhang
    Citation: Cancer Cell International 2024 24:91
  2. Patients with colorectal cancer (CRC) with liver metastasis or drug resistance have a poor prognosis. Previous research has demonstrated that PPP2R1B inactivation results in the development of CRC. However, th...

    Authors: Wei Liu, Jingtong Tang, Wei Gao, Jian Sun, Gang Liu and Jianping Zhou
    Citation: Cancer Cell International 2024 24:90
  3. Cancer chemoresistance is a problematic dilemma that significantly restrains numerous cancer management protocols. It can promote cancer recurrence, spreading of cancer, and finally, mortality. Accordingly, en...

    Authors: Samar Sami Alkafaas, Mohamed I. Elsalahaty, Doha F. Ismail, Mustafa Ali Radwan, Sara Samy Elkafas, Samah A. Loutfy, Rami M. Elshazli, Narjes Baazaoui, Ahmed Ezzat Ahmed, Wael Hafez, Mohanad Diab, Mohamed Sakran, Mohamed T. El-Saadony, Khaled A. El-Tarabily, Hani K. Kamal and Mohamed Hessien
    Citation: Cancer Cell International 2024 24:89
  4. Many cancer-related deaths including melanoma result from metastases that develop months or years after the initial cancer therapy. Even the most effective drugs and immune therapies rarely eradicate all tumor...

    Authors: Kathrin Singvogel and Birgit Schittek
    Citation: Cancer Cell International 2024 24:88
  5. As a key enzyme in ceramide synthesis, longevity assurance homologue 2 (LASS2) has been indicated to act as a tumour suppressor in a variety of cancers. Ferroptosis is involved in a variety of tumour processes...

    Authors: Yunfei Huang, Jie Du, Dan Li, Wei He, Zhouheng Liu, Li Liu, Xiaoli Yang, Xiaoming Cheng, Rui Chen and Yan Yang
    Citation: Cancer Cell International 2024 24:87
  6. The role of Acyl-CoA dehydrogenase long chain (ACADL) in different tumor types had different inhibiting or promoting effect. However, its role in non-small cell lung cancer (NSCLC) carcinogenicity is not clear.

    Authors: Kegong Chen, Chunqiao Hong, Weibo Kong, Guanghua Li, Zhuang Liu, Kechao Zhu, Chen Lu, Panpan Si, Pan Gao, Guangyao Ning and Renquan Zhang
    Citation: Cancer Cell International 2024 24:86
  7. SLC25A17, a peroxisomal solute carrier, has been implicated in various physiological and pathological processes. However, its precise roles and underlying mechanisms in triple-negative breast cancer (TNBC) rem...

    Authors: Haiting Zhou, Jiahao Li, Yi He, Xiaohui Xia, Junxia Liu and Huihua Xiong
    Citation: Cancer Cell International 2024 24:85
  8. The incidence of multiple primary cancers (MPC), especially involving primary lung cancer (PLC) and primary hematologic malignancies (PHM), is rising. This study aims to analyze clinicopathological features, g...

    Authors: Mengchen Lyu, Lifeng Luo, Ling Zhou, Xiangran Feng, Jin Yang, Ziwei Xu, Xianwen Sun, Zhiyao Bao, Xiaofei Wang, Beili Gao and Yi Xiang
    Citation: Cancer Cell International 2024 24:84
  9. Apatinib was the first anti-angiogenic agent approved for treatment of metastatic gastric cancer (GC). However, the emergence of resistance was inevitable. Thus investigating new and valuable off-target effect...

    Authors: Bei Zhang, Yan Chen, Xinqi Chen, Zhiyao Ren, Hong Xiang, Lipeng Mao and Guodong Zhu
    Citation: Cancer Cell International 2024 24:83
  10. Acute myeloid leukemia (AML) is a malignancy of the hematopoietic system, and childhood AML accounts for about 20% of pediatric leukemia. ANP32B, an important nuclear protein associated with proliferation, has...

    Authors: Xiaomei Wan, Jianwei Wang, Fang Fang, Yixin Hu, Zimu Zhang, Yanfang Tao, Yongping Zhang, Juanjuan Yu, Yumeng Wu, Bi Zhou, Hongli Yin, Li Ma, Xiaolu Li, Ran Zhuo, Wei Cheng, Shuqi Zhang…
    Citation: Cancer Cell International 2024 24:81
  11. Cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC) still present a huge threaten to women’s health, especially the local advanced patients. Hence, developing more effectiveness prognostic ...

    Authors: Xiaomei Chen, Xunhu Dong, Hong Li, Tingting Wu, Haoyin Liu, Jie Wu, Wei Ge, Lingji Hao and Zhe Zhang
    Citation: Cancer Cell International 2024 24:80
  12. Hepatocellular carcinoma (HCC) cells usually show strong resistance to chemotherapy, which not only reduces the efficacy of chemotherapy but also increases the side effects. Regulation of autophagy plays an im...

    Authors: Lili Sun, Yaru Li, Renshuang Zhao, Qinlei Fan, Fei Liu, Yilong Zhu, Jicheng Han, Yunyun Liu, Ningyi Jin, Xiao Li and Yiquan Li
    Citation: Cancer Cell International 2024 24:79
  13. Liver specific genes (LSGs) are crucial for hepatocyte differentiation and maintaining normal liver function. A deep understanding of LSGs and their heterogeneity in hepatocellular carcinoma (HCC) is necessary...

    Authors: Xiuzhi Zhang, Zhefeng Xiao, Xia Zhang, Ningning Li, Tao Sun, JinZhong Zhang, Chunyan Kang, Shasha Fan, Liping Dai and Xiaoli liu
    Citation: Cancer Cell International 2024 24:78
  14. Ferroptosis is a form of regulated cell death characterized by iron-dependent lipid peroxidation. Its role in cancer metastasis remains unclear. In this study, we aimed to investigate the potential involvement...

    Authors: Juan Sun, Jie Li, Kostas Pantopoulos, Yuqin Liu, Yixuan He, Weiming Kang and Xin Ye
    Citation: Cancer Cell International 2024 24:77
  15. To examine the role of RhoB expression in relation to chemotherapy response, clinical outcomes and associated signaling pathways in colorectal cancer patients.

    Authors: Maria Kopsida, Na Liu, Angeliki Kotti, Jing Wang, Lasse Jensen, Ganesan Jothimani, Camilla Hildesjo, Staffan Haapaniemi, Wen Zhong, Surajit Pathak and Xiao-Feng Sun
    Citation: Cancer Cell International 2024 24:75
  16. Breast cancer is the most prevalent female tumor, of which triple-negative breast cancer (TNBC) accounts for about 15%. Characterized by its aggressive nature and limited treatment options, TNBC currently stan...

    Authors: Mei Zhao, Panling Xu, Wenjing Shi, Juan Wang, Ting Wang and Ping Li
    Citation: Cancer Cell International 2024 24:74
  17. Rho guanine nucleotide dissociation inhibitor 1 (RhoGDI1) plays an important role in diverse cellular processes by regulating Rho guanosine triphosphate (GTP)ases activity. RhoGDI1 phosphorylation regulates th...

    Authors: Jeewon Lim, Yo Sep Hwang, Hyang Ran Yoon, Jiyun Yoo, Suk Ran Yoon, Haiyoung Jung, Hee Jun Cho and Hee Gu Lee
    Citation: Cancer Cell International 2024 24:73
  18. Glioblastoma (GBM) is the most lethal primary brain tumor in adult, characterized by highly aggressive and infiltrative growth. The current therapeutic management of GBM includes surgical resection followed by...

    Authors: Giorgia Castellani, Mariachiara Buccarelli, Quintino Giorgio D’Alessandris, Ramona Ilari, Andrea Cappannini, Francesca Pedini, Alessandra Boe, Valentina Lulli, Isabella Parolini, Stefano Giannetti, Mauro Biffoni, Vincenzo Zappavigna, Giovanna Marziali, Roberto Pallini and Lucia Ricci-Vitiani
    Citation: Cancer Cell International 2024 24:72
  19. Gastric cancer (GC) stands as a prevalent and deadly global malignancy. Despite its role as a preoperative neoadjuvant therapy, Apatinib’s effectiveness is curtailed among GC patients exhibiting elevated YY1 e...

    Authors: Zi-Han Geng, Jun-Xian Du, Yue-Da Chen, Pei-Yao Fu, Ping-Hong Zhou, Wen-Zheng Qin and Yi-Hong Luo
    Citation: Cancer Cell International 2024 24:71
  20. Glioblastoma (GBM) is the most common brain tumor with the worst prognosis. Temozolomide is the only first-line drug for GBM. Unfortunately, the resistance issue is a classic problem. Therefore, it is essentia...

    Authors: Yizhi Zhang, Wan Li, Yihui Yang, Sen Zhang, Hong Yang, Yue Hao, Xu Fang, Guanhua Du, Jianyou Shi, Lianqiu Wu and Jinhua Wang
    Citation: Cancer Cell International 2024 24:69

    The Correction to this article has been published in Cancer Cell International 2024 24:293

  21. Cuproptosis-related genes (CRGs) are associated with lung adenocarcinoma. However, the links between CRGs and non-small-cell lung cancer (NSCLC) are not clear. In this study, we aimed to develop two cuproptosi...

    Authors: Yijie Tang, Tianyi Wang, Qixuan Li and Jiahai Shi
    Citation: Cancer Cell International 2024 24:68
  22. Targeted drug delivery is one of the attractive ways in which cancer treatment can significantly reduce side effects. In the last two decades, the use of antibodies as a tool for accurate detection of cancer h...

    Authors: Mohadeseh Haji Abdolvahab, Pegah Karimi, Nasrin Mohajeri, Mohammad Abedini and Hamed Zare
    Citation: Cancer Cell International 2024 24:67
  23. Acute myeloid leukemia (AML) is a malignant hematologic disease caused by gene mutations and genomic rearrangements in hematologic progenitors. The PHF6 (PHD finger protein 6) gene is highly conserved and loca...

    Authors: Shengnan Yuan, Mingming Gao, Yizhou Wang, Yanjie Lan, Mengrou Li, Yuwei Du, Yue Li, Wen Ju, Yujin Huang, Ke Yuan and Lingyu Zeng
    Citation: Cancer Cell International 2024 24:66
  24. Pediatric T-cell acute lymphoblastic leukemia (T-ALL) poses significant challenges due to its aggressive nature and resistance to standard treatments. Long non-coding RNAs (lncRNAs) have emerged as potential b...

    Authors: Pankaj Sharma, Parminder kaur, Prateek Bhatia, Amita Trehan, Sreejesh Sreedharanunni and Minu Singh
    Citation: Cancer Cell International 2024 24:65
  25. Esophageal cancer (EC) is a global canker notorious for causing high mortality due to its relentless incidence rate, convoluted with unyielding recurrence and metastasis. However, these intricacies of EC are a...

    Authors: Obed Boadi Amissah, Wenfang Chen, Jean de Dieu Habimana, Yirong Sun, Lihui Lin, Yujie Liu, Ling Wang, Zhaoming Liu, Omar Mukama, Rajesh Basnet, Hohua Liu, Junyi Li, Xuanyan Ding, Lingshuang Lv, Min Chen, Yalin Liang…
    Citation: Cancer Cell International 2024 24:64
  26. The incidence of melanoma, the most lethal form of skin cancer, has increased due to ultraviolet exposure. The treatment of advanced melanoma, particularly metastatic cases, remains challenging with poor outco...

    Authors: Ming-yun Hsieh, Sheng-Kai Hsu, Tzu-Yu Liu, Chang-Yi Wu and Chien-Chih Chiu
    Citation: Cancer Cell International 2024 24:63
  27. m6A modification has close connection with the occurrence, development, and prognosis of tumors. This study aimed to explore the roles of m6A modification and its related mechanisms in non-small cell lung canc...

    Authors: Xianxiu Ji, Xiaoying Wan, Hui Sun, Qinfang Deng, Shuyan Meng, Boxiong Xie and Songwen Zhou
    Citation: Cancer Cell International 2024 24:61
  28. Glioblastoma (GBM) characterized by immune escape is the most malignant primary brain tumors, which has strong immunosuppressive effect. Programmed death ligand-1 (PD-L1) is a recognized immunosuppressive memb...

    Authors: Leilei Zhao, Yudi Wang, Peizheng Mu, Xuehua Zhang, Ruomei Qi, Yurui Zhang, He Zhang, Xiao Zhu, Zhouyan Dong and Yucui Dong
    Citation: Cancer Cell International 2024 24:60
  29. Peroxiredoxin 3 (PRDX3), a mitochondrial hydrogen peroxide scavenger, is known to be upregulated during tumorigenesis and cancer progression. In this study, we provide evidence for the first time that PRDX3 co...

    Authors: Pei-Jou Chua, Suet-Hui Ow, Cheng-Teng Ng, Wan-Hong Huang, Jie-Ting Low, Puay Hoon Tan, Michael W.Y. Chan and Boon-Huat Bay
    Citation: Cancer Cell International 2024 24:59
  30. Tongue squamous cell carcinoma (TSCC) is an aggressive oral cancer with a high incidence of metastasis and poor prognosis. We aim to identify and verify potential biomarkers for TSCC using bioinformatics analy...

    Authors: Huixin Dou, Can Song, Xiaoyan Wang, Zhien Feng, Yingying Su and Hao Wang
    Citation: Cancer Cell International 2024 24:58
  31. AlkB homolog 1, histone H2A dioxygenase (ALKBH1), a crucial enzyme involved in RNA demethylation in humans, plays a significant role in various cellular processes. While its role in tumor progression is well-e...

    Authors: Renin Chang, Kuan-Hao Tsui, Li-Fei Pan and Chia-Jung Li
    Citation: Cancer Cell International 2024 24:57
  32. About 30% of Prostate cancer (PCa) patients progress to metastatic PCa that remains largely incurable. This evidence underlines the need for the development of innovative therapies. In this direction, the pote...

    Authors: Valeria Pecci, Fabiola Troisi, Aurora Aiello, Sara De Martino, Angela Carlino, Vincenzo Fiorentino, Cristian Ripoli, Dante Rotili, Francesco Pierconti, Maurizio Martini, Manuela Porru, Francesco Pinto, Antonello Mai, Pier Francesco Bassi, Claudio Grassi, Carlo Gaetano…
    Citation: Cancer Cell International 2024 24:56
  33. Emerging data point to the critical role of snoRNA in the emergence of different types of cancer, but scarcely in breast cancer (BC). This study aimed to clarify the differential expressions and potential diag...

    Authors: Xiao Li, Xuan Zhao, Li Xie, Xingguo Song and Xianrang Song
    Citation: Cancer Cell International 2024 24:55
  34. Ovarian cancer (OC) has the highest mortality rate among all gynecological malignancies. A hypoxic microenvironment is a common feature of solid tumors, including ovarian cancer, and an important driving facto...

    Authors: Jiaqi Xu, Fei Wu, Yue Zhu, Tiantian Wu, Tianyue Cao, Wenxin Gao, Meng Liu, Weifeng Qian, Guannan Feng, Xiaoxue Xi and Shunyu Hou
    Citation: Cancer Cell International 2024 24:54
  35. Ovarian cancer (OV) is the most lethal gynecological malignancy worldwide, with high recurrence rates. Anoikis, a newly-acknowledged form of programmed cell death, plays an essential role in cancer progression...

    Authors: Jiani Yang, Yue Zhang, Shanshan Cheng, Yanna Xu, Meixuan Wu, Sijia Gu, Shilin Xu, Yongsong Wu, Chao Wang and Yu Wang
    Citation: Cancer Cell International 2024 24:53
  36. A minute fraction of patients stands to derive substantial benefits from immunotherapy, primarily attributable to immune evasion. Our objective was to formulate a predictive signature rooted in genes associate...

    Authors: Xu Wang, Shixin Chan, Jiajie Chen, Yuanmin Xu, Longfei Dai, Qijun Han, Zhenglin Wang, Xiaomin Zuo, Yang Yang, Hu Zhao, Ming Wang, Chen Wang, Zichen Li, Huabing Zhang and Wei Chen
    Citation: Cancer Cell International 2024 24:52
  37. Engrailed homeobox 1 (EN1) is a candidate oncogene that is epigenetically modified in salivary adenoid cystic carcinoma (SACC). We investigated the expression of EN1 in SACC tissues and cells, EN1 promoter methyl...

    Authors: Yajuan Cui, Ye Zhang, Yuping Liu, Zheng Zhou, Lijing Zhu and Chuan-Xiang Zhou
    Citation: Cancer Cell International 2024 24:51
  38. Although a combination of immune checkpoint inhibitors (ICIs) is recommended as the first line treatment option for metastatic renal cell carcinoma (mRCC), several immune-related adverse events (irAEs) occur, ...

    Authors: Jee Soo Park, Myung Eun Lee, Jongchan Kim, Keunhee Oh, Namhee Lee, Minsun Jung, Won Sik Jang and Won Sik Ham
    Citation: Cancer Cell International 2024 24:50
  39. Luminal breast cancer (BC) is a prevalent subtype associated with an increased risk of late disease recurrence and mortality. Long noncoding RNAs (lncRNAs) likely play significant roles in regulating tissue-sp...

    Authors: Yue Meng, Dianrong Zhou, Ying Luo, Jierong Chen and Hui Li
    Citation: Cancer Cell International 2024 24:49
  40. The diagnosis of T-cell lymphomas is typically established through a multiparameter approach that combines clinical, morphologic, immunophenotypic, and genetic features, utilizing a variety of histopathologic ...

    Authors: Muhammad Sufyan Bin Masroni, Gracie Wee Ling Eng, Ah-Jung Jeon, Yuan Gao, He Cheng, Sai Mun Leong, Jit Kong Cheong, Susan Swee-Shan Hue and Soo Yong Tan
    Citation: Cancer Cell International 2024 24:48
  41. Long noncoding RNAs (lncRNAs) are significant contributors to various human malignancies. The aberrant expression of lncRNA LINC00894 has been reported in various human malignancies. We aimed to illustrate the...

    Authors: Xiang Zhou, Lisha Chang, Qiaoqiao Liang, Rongjie Zhao, Yong Xiao, Zheng Xu and Leitao Yu
    Citation: Cancer Cell International 2024 24:47
  42. Recently, the presence of different nanoparticles (NPs) has developed targeting drug delivery in treatment of cancer cell. Targeted drug delivery systems using NPs have shown great promise in improving the eff...

    Authors: Akram Firouzi Amandi, Zahra Bahmanyar, Mehdi Dadashpour, Mehrnoosh Lak, Mohammad Natami, Yusuf Döğüş, Mahsa Alem and Omid Ali Adeli
    Citation: Cancer Cell International 2024 24:46
  43. Pyroptosis, an inflammatory form of programmed cell death, has been implicated in the pathogenesis and progression of several cancers. However, the significance of pyroptosis-related genes (PRGs) in papillary ...

    Authors: Fang Li, Rui Du, Jiedong Kou, Jingting Li, Le Zhou, Daqi Zhang, Yantao Fu, Gianlorenzo Dionigi, Simona Bertoli, Hui Sun and Nan Liang
    Citation: Cancer Cell International 2024 24:45
  44. Gastric cancer (GC) ranks fifth for morbidity and third for mortality worldwide. The N6-methyladenosine (m6A) mRNA methylation is crucial in cancer biology and progression. However, the relationship between m6A m...

    Authors: Zehua Wang, Chen Chen, Jiao Shu, Jiaoyu Ai, Yihan Liu, Haoyue Cao, Yongxu Jia and Yanru Qin
    Citation: Cancer Cell International 2024 24:44
  45. The FGF/FGFR signaling pathway plays a critical role in human cancers. We analyzed the anti-tumor effect of AZD4547, an inhibitor targeting the FGF/FGFR pathway, in epithelial ovarian cancer (EOC) and strategi...

    Authors: Yoo-Young Lee, Ji-Yoon Ryu, Young-Jae Cho, Ju-Yeon Choi, Jung-Joo Choi, Chel Hun Choi, Jason K. Sa, Jae Ryoung Hwang and Jeong-Won Lee
    Citation: Cancer Cell International 2024 24:43
  46. Circular RNAs (circRNAs) are involved in the regulation of progression and drug resistance in ovarian cancer (OC). In the present study, we aimed to explore the role of circRAD23B, a newly identified circRNA, ...

    Authors: Hui Wang, Yashuang Zhang, Huixian Miao, Ting Xu, Xianglin Nie and Wenjun Cheng
    Citation: Cancer Cell International 2024 24:42

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