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  1. Endometrial cancer (EC) is a common malignancy of the female reproductive system. Circular RNAs (circRNAs) were demonstrated to exert critical roles in cancers, including EC. This study aimed to investigate th...

    Authors: Youjuan Jia, Meijuan Liu and Shuxia Wang

    Citation: Cancer Cell International 2020 20:412

    Content type: Primary research

    Published on:

  2. Dysregulation of lncRNAs is frequent in glioma and has emerged as an important mechanism involved in tumorigenesis. Previous analysis of Chinese Glioma Genome Atlas (CGGA) database indicated that LBX2-AS1 expr...

    Authors: Qunbang Chen, Jian Gao, Yingjia Zhao and Ruizhe Hou

    Citation: Cancer Cell International 2020 20:411

    Content type: Primary research

    Published on:

  3. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Chia-Chen Hsu, Yu-Fu Su, Kuo-Yang Tsai, Feng-Chih Kuo, Chi-Fu Chiang, Chu-Yen Chien, Ying-Chen Chen, Chien-Hsing Lee, Yu-Chiao Wu, Kun Wang, Shyun-Yeu Liu and Yi-Shing Shieh

    Citation: Cancer Cell International 2020 20:410

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2020 20:300

  4. Diagnosis of metastatic castrate resistant prostate cancer (mCRPC) with current biomarkers is difficult and often results in unnecessary invasive procedures as well as over-diagnosis and over-treatment. There ...

    Authors: Shengri Tian, Zhen Lei, Zuo Gong, Zhonghai Sun, Dongyuan Xu and Minhu Piao

    Citation: Cancer Cell International 2020 20:409

    Content type: Review

    Published on:

  5. Nasopharyngeal carcinoma (NPC) is an epithelial malignancy with high morbidity rates in the east and southeast Asia. The molecular mechanisms of NPC remain largely unknown. We explored the pathogenesis, potent...

    Authors: Yuanji Xu, Xinyi Huang, Wangzhong Ye, Yangfan Zhang, Changkun Li, Penggang Bai, Zhizhong Lin and Chuanben Chen

    Citation: Cancer Cell International 2020 20:408

    Content type: Primary research

    Published on:

  6. Oral squamous cell carcinoma (OSCC) is a more common cancer in the world. Emerging evidence suggests that circular RNAs (circRNAs) participate in the progression of OSCC. However, the role of circ_0000140 in O...

    Authors: Jia Guo, Yuanyuan Su and Meng Zhang

    Citation: Cancer Cell International 2020 20:407

    Content type: Primary research

    Published on:

  7. Hepatocellular carcinoma (HCC) is a high mortality disease, the fifth most general cancer worldwide, and the second leading to cancer-related deaths, with more than 500,000 new patients diagnosed each year. Fi...

    Authors: Zeng-hong Wu and Dong-liang Yang

    Citation: Cancer Cell International 2020 20:406

    Content type: Primary research

    Published on:

  8. Despite being one of the leading cancer types in the world, the diagnosis of oral cancer and its suitable therapeutic options remain limited. This study aims to investigate the single and chemosensitizing effe...

    Authors: In-Hyoung Yang, Seung-Hyun Hong, Minjung Jung, Chi-Hyun Ahn, Hye-Jung Yoon, Seong Doo Hong, Sung-Dae Cho and Ji-Ae Shin

    Citation: Cancer Cell International 2020 20:405

    Content type: Primary research

    Published on:

  9. Circular RNAs (circRNAs) play vital roles in hepatocellular carcinoma development. However, the role and mechanism of circRNA hsa_circ_0000517 (circ_0000517) in hepatocellular carcinoma development were largel...

    Authors: Shuwei He, Jianzeng Yang, Shitao Jiang, Yuan Li and Xingmin Han

    Citation: Cancer Cell International 2020 20:404

    Content type: Primary research

    Published on:

  10. Long non-coding RNA (lncRNA) BM742401 is a tumor suppressor in gastric cancer and chronic lymphocytic leukemia. As the promoter and coding region of BM742401 are fully embedded in a CpG island, we hypothesized th...

    Authors: Zhenhai Li, Shaji Kumar, Dong-Yan Jin, George A. Calin, Wee-Joo Chng, Kam-Leung Siu, Ming-Wai Poon and Chor Sang Chim

    Citation: Cancer Cell International 2020 20:403

    Content type: Primary research

    Published on:

  11. Breast cancer (BC) is the most common malignancy among women. Emerging studies have demonstrated that circular RNA (circRNA) zinc finger RNA binding protein (circZFR) serves as a crucial regulator in many huma...

    Authors: Zhuo Chen, Fang Wang, Youyi Xiong, Nan Wang, Yuanting Gu and Xinguang Qiu

    Citation: Cancer Cell International 2020 20:400

    Content type: Primary research

    Published on:

  12. Iron metabolism disorder is closely associated with several malignant tumors, however the mechanisms underlying iron and the carcinogenesis in osteosarcoma are not yet well understood.

    Authors: Shuo Ni, Yanbin Kuang, Yin Yuan and Baoqing Yu

    Citation: Cancer Cell International 2020 20:399

    Content type: Primary research

    Published on:

  13. Oral squamous cell carcinoma (OSCC), a form of head and neck squamous cell carcinoma (HNSCC) has a poor 5-year survival rate. OSCC patients are often treated with cisplatin but resistance to chemotherapy is of...

    Authors: Xiao-han Li, Dan Li, Chang Liu, Ming-ming Zhang, Xiao-jiao Guan and Ya-ping Fu

    Citation: Cancer Cell International 2020 20:398

    Content type: Primary research

    Published on:

  14. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Tong Li, Qiaofei Liu, Ronghua Zhang, Quan Liao and Yupei Zhao

    Citation: Cancer Cell International 2020 20:397

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2020 20:341

  15. Studies have shown that miR-502-5p functions as a tumor suppressor and is associated with tumor growth and metastasis. This study intends to uncover the potential mechanism of miR-502-5p functioning as a tumor...

    Authors: Wendao You, Xiaoyu Liu, Yang Yu, Chen Chen, Yujia Xiong, Yiting Liu, Yibin Sun, Chenhuan Tan, Hanshuo Zhang, Yadong Wang and Rui Li

    Citation: Cancer Cell International 2020 20:395

    Content type: Primary research

    Published on:

  16. Glioblastoma multiforme (GBM) is the most seriously brain tumor with extremely poor prognosis. Recent research has demonstrated that competitive endogenous RNA (ceRNA) network which long noncoding RNAs (lncRNA...

    Authors: Xiaolong Zhu, Lan Jiang, Hui Yang, Tianbing Chen, Xingwei Wu and Kun Lv

    Citation: Cancer Cell International 2020 20:393

    Content type: Primary research

    Published on:

  17. The situation faced by breast cancer patients, especially those with triple-negative breast cancer, is still grave. More effective therapeutic targets are needed to optimize the clinical management of breast c...

    Authors: Wei Peng, Jian-Di Li, Jing-Jing Zeng, Xiao-Ping Zou, Deng Tang, Wei Tang, Min-Hua Rong, Ying Li, Wen-Bin Dai, Zhong-Qing Tang, Zhen-Bo Feng and Gang Chen

    Citation: Cancer Cell International 2020 20:392

    Content type: Primary research

    Published on:

  18. Circular RNAs (circRNAs) are a new group of non-coding RNAs that play vital roles in cancer occurrence, including gastric cancer (GC). Nevertheless, the role and underlying regulatory mechanisms of circHIPK3 i...

    Authors: Qingchun Li, Yuan Tian, Yun Liang and Chang Li

    Citation: Cancer Cell International 2020 20:391

    Content type: Primary research

    Published on:

  19. The introduction of combined conventional cytostatics and pathway-specific inhibitors has opened new treatment options for several cancer types including hematologic neoplasia such as leukaemias. As the detail...

    Authors: L.-M. Sklarz, Y. S. Gladbach, M. Ernst, M. Hamed, C. Roolf, S. Sender, J. Beck, E. Schütz, S. Fischer, S. Struckmann, C. Junghanss, G. Fuellen and H. Murua Escobar

    Citation: Cancer Cell International 2020 20:390

    Content type: Primary research

    Published on:

  20. Recently, extensive evidence has clarified the crucial role of circular RNAs (circRNAs) as a pro-tumor or anti-cancer participant in human malignancies. A new circRNA derived from oxysterol binding protein lik...

    Authors: Shanshan Yang, Yiwen Jiang, Xiaoli Ren, Dan Feng, Liaoyun Zhang, Deying He, Shiyao Hong, Li Jin, Fang Zhang and Shun Lu

    Citation: Cancer Cell International 2020 20:389

    Content type: Primary research

    Published on:

  21. Esophageal squamous cell carcinoma (ESCC) is one of the most frequent malignant tumors originated from digestive system around the world and the treatment was limited by the unclear mechanism. DNA polymerase e...

    Authors: Yongjun Zhu, Gang Chen, Yang Song, Zhiming Chen and Xiaofeng Chen

    Citation: Cancer Cell International 2020 20:388

    Content type: Primary research

    Published on:

  22. The incidence and death rate of non-small cell lung cancer (NSCLC) in China ranks the first among the malignant tumors. Circular RNA (circRNA) was reported to be involved in the progression of NSCLC. Our study...

    Authors: Liang Wang, Lantao Zhao and Yonghong Wang

    Citation: Cancer Cell International 2020 20:387

    Content type: Primary research

    Published on:

  23. The aim of this study was to identify prognostic long non-coding RNAs (lncRNAs) and develop a multi-lncRNA signature for suvival prediction in esophageal squamous cell carcinoma (ESCC).

    Authors: Lan zhang, Pan Li, Enjie Liu, Chenju Xing, Di Zhu, Jianying Zhang, Weiwei Wang and Guozhong Jiang

    Citation: Cancer Cell International 2020 20:386

    Content type: Primary research

    Published on:

  24. Cervical squamous cell carcinoma (CSCC) is one of the main causes of cancer-related deaths in women worldwide. The present study was conducted with the main objective of determining the potential role of recep...

    Authors: Jing Wang and Shengcai Chen

    Citation: Cancer Cell International 2020 20:385

    Content type: Primary research

    Published on:

  25. Melanoma is a cancer that has a high mortality rate in the absence of targeted therapy. Conventional therapies such as surgery, chemotherapy, and radiotherapy are associated with poor prognosis. The expression...

    Authors: Shaghayegh Haghjooy Javanmard, Golnaz Vaseghi, Ahmad Ghasemi, Laleh Rafiee, Gordon A. Ferns, Hajar Naji Esfahani and Reza Nedaeinia

    Citation: Cancer Cell International 2020 20:384

    Content type: Primary research

    Published on:

  26. The pathogenesis of multiple myeloma (MM) is not completely known. Uncovering the potential mechanism of MM initiation and progression is essential for identifying novel diagnostic and therapeutic targets. Her...

    Authors: Yan Wang, Quande Lin, Chunge Song, Ruojin Ma and Xiaojie Li

    Citation: Cancer Cell International 2020 20:383

    Content type: Primary research

    Published on:

  27. Pancreatic cancer is a common malignant tumor of the digestive tract. It has a high degree of malignancy and poor prognosis. Finding effective molecular markers has great significance for pancreatic cancer dia...

    Authors: Mu-jing Ke, Lian-dong Ji and Yi-xiong Li

    Citation: Cancer Cell International 2020 20:382

    Content type: Primary research

    Published on:

  28. Chemo-resistance is one of the main obstacles in the treatment of prostate cancer (PCa). Long non-coding RNA small nucleolar RNA host gene 6 (SNHG6) is involved in the chemo-resistance of various tumors. We ai...

    Authors: Chunhui Cao, Guanghai Sun and Chunlin Liu

    Citation: Cancer Cell International 2020 20:381

    Content type: Primary research

    Published on:

  29. Newcastle disease virus (NDV) has shown noticeable oncolytic properties, especially against cervical cancer. However, in order to improve the spread rate and oncotoxicity of the virus, employment of other ther...

    Authors: Seyed Mohammad Miri, Mir Saeed Ebrahimzadeh, Elahe Abdolalipour, Mahsa Yazdi, Hassan Hosseini Ravandi and Amir Ghaemi

    Citation: Cancer Cell International 2020 20:380

    Content type: Primary research

    Published on:

  30. The roots of Salvia miltiorrhiza are used in traditional Chinese medicine (TCM) and have high medicinal value. Tanshinone IIA (Tan IIA) is the active ingredient of Salvia miltiorrhiza which can inhibit the growth...

    Authors: Zi-Yuan Nie, Ming-Hui Zhao, Bao-Qian Cheng, Rong-Fang Pan, Tian-Rui Wang, Yan Qin and Xue-Jun Zhang

    Citation: Cancer Cell International 2020 20:379

    Content type: Primary research

    Published on:

  31. Growing evidence has demonstrated that glutathione peroxidases (GPXs) family genes play critical roles in onset and progression of human cancer. However, a systematic study regarding expression, diagnostic and...

    Authors: Weiyang Lou, Bisha Ding, Shuqian Wang and Peifen Fu

    Citation: Cancer Cell International 2020 20:378

    Content type: Primary research

    Published on:

  32. Breast cancer is a common malignancy in women. Among breast cancer types, triple-negative breast cancer (TNBC) tends to affect younger women, is prone to axillary lymph node, lung, and bone metastases; and has...

    Authors: Chengli Lu, Zhiyuan Ma, Xiaoming Cheng, Huichao Wu, Biguang Tuo, Xuemei Liu and Taolang Li

    Citation: Cancer Cell International 2020 20:377

    Content type: Review

    Published on:

  33. Numerous studies have shown that long noncoding RNAs play important roles in human cancer progression. Although zebrafish xenografts have recently become a novel in vivo model for human cancer research, whethe...

    Authors: Wenyi Shen, Juan Pu, Jing Sun, Bing Tan, Wei Wang, Lili Wang, Jianmeng Cheng and Yangsong Zuo

    Citation: Cancer Cell International 2020 20:376

    Content type: Primary research

    Published on:

  34. The aim of this study is to determine whether Hypoxanthine Guanine Phosphoribosyltransferase (HPRT) could be used as a biomarker for the diagnosis and treatment of B cell malignancies. With 4.3% of all new can...

    Authors: Michelle H. Townsend, Zac E. Ence, Taylor P. Cox, John E. Lattin, Weston Burrup, Michael K. Boyer, Stephen R. Piccolo, Richard A. Robison and Kim L. O’Neill

    Citation: Cancer Cell International 2020 20:375

    Content type: Primary research

    Published on:

  35. Glioma is the most primary central nervous system tumor in adults. The 5 year survival rate for glioma patients remains poor, although treatment strategies had improved in the past few decades. The cumulative ...

    Authors: Niya Long, Liangzhao Chu, Jun Jia, Shuo Peng, Yuan Gao, Hua Yang, Yaoming Yang, Yan Zhao and Jian Liu

    Citation: Cancer Cell International 2020 20:374

    Content type: Primary research

    Published on:

  36. Ovarian cancer (OC) is the most malignant tumor in the female reproductive system. About 75% of OC in complete remission of clinical symptoms still develop a recurrence. Therefore, searching for new treatment ...

    Authors: Fangfang Bi, Ying Chen and Qing Yang

    Citation: Cancer Cell International 2020 20:373

    Content type: Primary research

    Published on:

  37. Long non-coding RNAs (LncRNAs) have been increasingly confirmed to be abnormally expressed in human cancer and closely related to tumorigenesis. LncRNA ACTA2-AS1 is abnormally expressed in multiple tumors and ...

    Authors: Lingli Luo, Min Wang, Xianping Li, Can Luo, Shan Tan, Sheng Yin, Lei Liu and Xiaolin Zhu

    Citation: Cancer Cell International 2020 20:372

    Content type: Primary research

    Published on:

  38. Hepatocellular carcinoma (HCC) is the most aggressive and frequently diagnosed malignancy of the liver. Despite aggressive therapy, life expectancy of many patients in these cases is extended by only a few mon...

    Authors: Yi Xiao, Qiang Gong, Wenhong Wang, Fang Liu, Qinghong Kong, Feng Pan, Xiaoke Zhang, Changyan Yu, Shanshan Hu, Fang Fan, Sanhua Li and Yun Liu

    Citation: Cancer Cell International 2020 20:371

    Content type: Primary research

    Published on:

  39. Reversible acetylation of α-tubulin has been implicated in modulating microtuble structures and functions, which may subsequently involve in cellular apoptosis and autophage. But how to trigger apoptosis or au...

    Authors: Qilin Wang and Xiangguo Liu

    Citation: Cancer Cell International 2020 20:369

    Content type: Primary research

    Published on:

  40. T cell receptor gamma locus antisense RNA 1 (TRG-AS1) has been reported to involve in the progression of glioblastoma, however the role and its underlying molecular mechanism in hepatocellular carcinoma (HCC) ...

    Authors: Xuehu Sun, Yeben Qian, Xingyu Wang, Rongge Cao, Jianlin Zhang, Weidong Chen and Maoyong Fang

    Citation: Cancer Cell International 2020 20:367

    Content type: Primary research

    Published on:

  41. Mammary Paget’s disease (MPD) is an uncommon cutaneous intraepithelial malignancy with ulceration of the nipple or areola. Its pathogenesis and genomic mutation remain largely unknown and no cell lines are est...

    Authors: Bo Pan, Dongyi Zhao, Yaqian Liu, Na Li, Chen Song, Ning Li, Xuelu Li, Man Li and Zuowei Zhao

    Citation: Cancer Cell International 2020 20:365

    Content type: Primary research

    Published on:

  42. As a new kind of RNA, circular RNA (circRNA) is a endogenous non-coding RNA with circular structure, which has the characteristics of universality, stability, conservatism and specificity. CircRNA can specific...

    Authors: Xiaoqing Zhang, Ning Lu, Li Wang, Yixuan Wang, Minna Li, Ying Zhou, Honglin Yan, Manli Cui, Mingxin Zhang and Lingmin Zhang

    Citation: Cancer Cell International 2020 20:362

    Content type: Review

    Published on:

  43. Hepatocellular carcinoma (HCC) is the most common malignant heterogeneous disease in primary liver tumors. Circular RNA hsa_circ_0000517 (hsa_circ_0000517) is connected with HCC prognosis. Nevertheless, there ...

    Authors: Shuwei He, Zhengwu Guo, Qian Kang, Xu Wang and Xingmin Han

    Citation: Cancer Cell International 2020 20:360

    Content type: Primary research

    Published on:

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