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  1. In recent times, the intersection of nanotechnology and biomedical research has given rise to nanobiomedicine, a captivating realm that holds immense promise for revolutionizing diagnostic and therapeutic appr...

    Authors: Habib Ghaznavi, Reza Afzalipour, Samideh Khoei, Saman Sargazi, Sakine Shirvalilou and Roghayeh Sheervalilou
    Citation: Cancer Cell International 2024 24:160
  2. Single nuclear polymorphisms (SNPs) have been published to be correlated with multiple diseases. Transcription Factor 21 (TCF21) is a critical transcription factor involved in various types of cancers. However...

    Authors: Xinyi Zhou, Kuan Shen, Shuqing Cao, Pengyu Li, Jian Xiao, Jiacheng Dong, Quan Cheng, Li Hu, Zekuan Xu and Li Yang
    Citation: Cancer Cell International 2024 24:159
  3. Over the past decade, heat shock protein 90 (HSP90) inhibitors have emerged as promising anticancer drugs in solid and hematological malignancies. Flavokawain C (FKC) is a naturally occurring chalcone that has...

    Authors: YuQiang Hu, ChenJie Yu, LiangJun Cheng, Chang Zhong, Jun An, MingZhen Zou, Bing Liu and Xia Gao
    Citation: Cancer Cell International 2024 24:158
  4. Identifying molecular biomarkers for predicting responses to anti-cancer drugs can enhance treatment precision and minimize side effects. This study investigated the novel cancer-targeting mechanism of combini...

    Authors: Yu-Jeong Choi, Kangwook Lee, Seo Yeon Lee, Youngbin Kwon, Jaehyuk Woo, Chan-Yong Jeon and Seong-Gyu Ko
    Citation: Cancer Cell International 2024 24:156
  5. The exosome-mediated extracellular secretion of miRNAs occurs in many cancers, and RAB27A is a potent regulator of exosome secretion. For metastatic renal cell carcinoma (RCC), this study examines the mechanis...

    Authors: Dae Hyun Song, Jong Sil Lee, Jeong-Hee Lee, Dong Chul Kim, Jung Wook Yang, Min Hye Kim, Ji Min Na, Hyun-kyung Cho, Jiyun Yoo and Hyo Jung An
    Citation: Cancer Cell International 2024 24:153
  6. Ovarian cancer (OC) is a malignancy among female globally. Circular RNAs (circRNAs) are a family of circular endogenous RNAs generated from selective splicing, which take part in many traits. Former investigat...

    Authors: Zhongxin Yan, Changling Duan, Xi Li, Hao Wang, Shanji Li, Xuexin Zhou and Yi Miao
    Citation: Cancer Cell International 2024 24:152
  7. The purinergic P2X7 receptor (P2X7R) plays an important role in the crosstalk between pancreatic stellate cells (PSCs) and cancer cells, thus promoting progression of pancreatic ductal adenocarcinoma (PDAC). S...

    Authors: Lara Magni, Haoran Yu, Nynne M. Christensen, Mette H. Poulsen, Alexander Frueh, Ganga Deshar, Astrid Z. Johansen, Julia S. Johansen, Stephan A. Pless, Niklas R. Jørgensen and Ivana Novak
    Citation: Cancer Cell International 2024 24:148
  8. Colon cancer ranks third among global tumours and second in cancer-related mortality, prompting an urgent need to explore new therapeutic targets. C6orf15 is a novel gene that has been reported only in Sjogren...

    Authors: Jiankang Yu, Jian Sun, Jingtong Tang, Jiayu Xu, Guanru Qian and Jianping Zhou
    Citation: Cancer Cell International 2024 24:146
  9. Lung adenocarcinoma is a major public health problem with the low 5-year survival rate (15%) among cancers. Aberrant alterations of meiotic genes, which have gained increased attention recently, might contribu...

    Authors: Yating Liu, Lianlian Ouyang, Shiyao Jiang, Lu Liang, Yuanbing Chen, Chao Mao, Yiqun Jiang and Li Cong
    Citation: Cancer Cell International 2024 24:145
  10. Breast cancer is the most common cancer in women worldwide. Toxoplasma gondii (T. gondii) has shown anticancer activity in breast cancer mouse models, and exerted beneficial effect on the survival of breast cance...

    Authors: Hengming Ye, Xiaotao Zhou, Bike Zhu, Tiantian Xiong, Weile Huang, Feng He, Hui Li, Lihua Chen, Luying Tang and Zefang Ren
    Citation: Cancer Cell International 2024 24:144
  11. Hepatocellular carcinoma (HCC) is widely recognized for its unfavorable prognosis. Increasing evidence has revealed that LGALS3 has an essential function in initiating and developing several malignancies in hu...

    Authors: Yinghui Ren, Yongmei Qian, Qicheng Zhang, Xiaoping Li, Mingjiang Li, Wei Li, Pan Yang, Hengchang Ren, Hongxia Li, Yiqi Weng, Dengwen Li, Ke Xu and Wenli Yu
    Citation: Cancer Cell International 2024 24:142
  12. Prompt identification and assessment of the disease are essential for reducing the death rate associated with colorectal cancer (COL). Identifying specific causal or sensitive components, such as coding RNA (c...

    Authors: Navid Abedpoor, Farzaneh Taghian, Khosro Jalali Dehkordi and Kamran Safavi
    Citation: Cancer Cell International 2024 24:141
  13. The mitochondrial calcium uniporter (MCU) is a transmembrane protein facilitating the entry of calcium ions into mitochondria from the cell cytosol. Maintaining calcium balance is crucial for enhancing cellula...

    Authors: Chia-Jung Li, Yen-Dun Tony Tzeng, Jui-Hu Hsiao, Ling-Ming Tseng, Tzu-Sheng Hsu and Pei-Yi Chu
    Citation: Cancer Cell International 2024 24:140
  14. Immunogenic cell death (ICD) is closely related to anti-tumor therapy and regulates the tumor microenvironment (TME). This study aims to explore the molecular characteristics of ICD in acute myeloid leukemia (...

    Authors: Fangmin Zhong, Shuyang He, Ni Guo, Luyi Shi, Linlin Zhang, Hua Jin and Guangyao Kong
    Citation: Cancer Cell International 2024 24:139
  15. N6-methyladenosine (m6A) is important in regulating mRNA stability, splicing, and translation, and it also contributes to tumor development. However, there is still limited understanding of the comprehensive e...

    Authors: Yunxing Shi, Kai Li, Yichuan Yuan, Chenwei Wang, Zhiwen Yang, Dinglan Zuo, Yi Niu, Jiliang Qiu, Binkui Li, Yunfei Yuan and Wei He
    Citation: Cancer Cell International 2024 24:138
  16. Exosomes derived from tumor cells contribute to the pathogenesis of cancers. Metformin, the most usually used drug for type 2 diabetes, has been frequently investigated for anticancer effects. Here, we examine...

    Authors: Reza Abbasi, Vahid Nejati and Jafar Rezaie
    Citation: Cancer Cell International 2024 24:137
  17. Hydrogen sulfide (H2S) is a significant endogenous mediator that has been implicated in the progression of various forms of cancer including breast cancer (BC). Cystathionine-β-synthase (CBS), cystathionine-γ-lya...

    Authors: Alyaa Dawoud, Rana A. Youness, Heba Nafea, Tamer Manie, Carole Bourquin, Csaba Szabo, Reham M. Abdel-Kader and Mohamed Z. Gad
    Citation: Cancer Cell International 2024 24:136
  18. One of the contributing factors in the diagnosis and treatment of most cancers is the identification of their surface antigens. Cancer tissues or cells have their specific antigens. Some antigens that are pres...

    Authors: Tina Nayerpour Dizaj, Abolfazl Doustmihan, Behnaz Sadeghzadeh Oskouei, Morteza Akbari, Mehdi Jaymand, MirAhmad Mazloomi and Rana Jahanban-Esfahlan
    Citation: Cancer Cell International 2024 24:135
  19. Some noncoding RNAs (ncRNAs) carry open reading frames (ORFs) that can be translated into micropeptides, although noncoding RNAs (ncRNAs) have been previously assumed to constitute a class of RNA transcripts w...

    Authors: He Zhou, Yan Wu, Ji Cai, Dan Zhang, Dongfeng Lan, Xiaofang Dai, Songpo Liu, Tao Song, Xianyao Wang, Qinghong Kong, Zhixu He, Jun Tan and Jidong Zhang
    Citation: Cancer Cell International 2024 24:134
  20. The metabolism of cancer cells generally differs from that of normal cells. Indeed, most cancer cells have a high rate of glycolysis, even at normal oxygen concentrations. These metabolic properties can potent...

    Authors: Claire Muller, Victorine Lacroix-Malgras, Jérôme Kluza, William Laine, Yonca Güler, Frédéric Bost, Michel Boisbrun, Sabine Mazerbourg and Stéphane Flament
    Citation: Cancer Cell International 2024 24:132
  21. Extensive exploration of the molecular subtypes of triple-negative breast cancer (TNBC) is critical for advancing precision medicine. Notably, the luminal androgen receptor (LAR) subtype has attracted attentio...

    Authors: Ya-Xin Zhao, Han Wang, Si-Wei Zhang, Wei-Xin Zhang, Yi-Zhou Jiang and Zhi-Ming Shao
    Citation: Cancer Cell International 2024 24:131
  22. Fatty acids synthesis and metabolism (FASM)-driven lipid mobilization is essential for energy production during nutrient shortages. However, the molecular characteristics, physiological function and clinical p...

    Authors: Ai Zhengdong, Xing Xiaoying, Fu Shuhui, Liang Rui, Tang Zehui, Song Guanbin, Yang Li, Tang Xi and Liu Wanqian
    Citation: Cancer Cell International 2024 24:130
  23. Cancer-associated fibroblasts (CAFs) drive cancer progression and treatment failure on one hand, while their tumor-restraining functions are also observed on the other. Recent single cell RNA sequencing (scRNA...

    Authors: Ze Gao, Ning Zhang, Bingzheng An, Dawei Li, Zhiqing Fang and Dawei Xu
    Citation: Cancer Cell International 2024 24:127
  24. Bladder cancer (BCa) stands out as a prevalent and highly lethal malignancy worldwide. Chemoresistance significantly contributes to cancer recurrence and progression. Traditional Tumor Node Metastasis (TNM) st...

    Authors: Tingting Cai, Tao Feng, Guangren Li, Jin Wang, Shengming Jin, Dingwei Ye and Yiping Zhu
    Citation: Cancer Cell International 2024 24:125
  25. Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent renal cancers, and the molecular mechanisms underlying its progression are still not fully understood. The expression of CCDC25, a notably u...

    Authors: Hongpei Tan, Jiahao Liu, Yanan Li, Ze Mi, Baiying Liu and Pengfei Rong
    Citation: Cancer Cell International 2024 24:124
  26. GBM, also known as glioblastoma multiforme, is the most prevalent and lethal type of brain cancer. The cell proliferation, invasion, angiogenesis, and treatment of gliomas are significantly influenced by oxida...

    Authors: Kan Wang, Yifei Xiao, Ruipeng Zheng and Yu Cheng
    Citation: Cancer Cell International 2024 24:123
  27. Prostate cancer (PCa) is one of the most prevalent cancers in men and is associated with high mortality and disability rates. β-hydroxybutyrate (BHB), a ketone body, has received increasing attention for its r...

    Authors: Yifan Zhang and Yunlong Li
    Citation: Cancer Cell International 2024 24:121
  28. Triple-negative breast cancer (TNBC) is widely recognized as the most aggressive form of breast cancer, occurring more frequently in younger patients and characterized by high heterogeneity, early distant meta...

    Authors: Lijuan Weng, Jianliang Zhou, Shenchao Guo, Nong Xu and Ruishuang Ma
    Citation: Cancer Cell International 2024 24:120
  29. This study aimed to construct a model based on 23 enrolled molecules to evaluate prognoses of pT2/3N0M0 esophageal squamous cell carcinoma (ESCC) patients with up to 20 years of follow-up.

    Authors: Wen-Mei Jiang, Jia-Yuan Tian, Yi-Han Guo, Li-Hong Qiu, Xing-Yu Luo, Yang-Yu Huang, Hao Long, Lan-Jun Zhang, Peng Lin, Xin-Xin Xu, Lei-Lei Wu and Guo-Wei Ma
    Citation: Cancer Cell International 2024 24:119
  30. Increasing evidence proves that RBP7 plays a significant role in breast cancer (BC). The present study was aimed to investigate the mechanism of RBP7.

    Authors: Yue Yu, Zhihua Xu, Hao Zhou, Ruyan Xu, Jia Xu, Wenjun Liu, Yuxin Wu, Yue Qiu, Guangbo Zhang, Xue Huang and Yan Chen
    Citation: Cancer Cell International 2024 24:118
  31. Multiple myeloma (MM) is the second most common refractory hematologic cancer. Searching for new targets and prognostic markers for MM is significant.

    Authors: Hong Luo, Chengyun Pan, Li Wang, Lin Zheng, Shuyun Cao, Xiuying Hu, Tianzhen Hu, Naiqin Zhao, Qin Shang and Jishi Wang
    Citation: Cancer Cell International 2024 24:117
  32. Mesenchymal stem/stromal cells (MSCs) have been acknowledged as the most important stromal cells in the bone marrow (BM) microenvironment for physiologic hematopoiesis and the concomitant hematologic malignanc...

    Authors: Yu Lu, Chaohui Zheng, Wenxia Zhang, Xuan Liu, Ziwei Zhou, Zhenzhen Wang, Huan Hua, Zhengrong Song, Xuejun Zhang, Shuyi Liu, Leisheng Zhang and Fuxu Wang
    Citation: Cancer Cell International 2024 24:116
  33. Esophageal squamous cell carcinoma (ESCC) is one of the leading causes of digestive system tumor related death in the world. Unfortunately, effective chemopreventive agent is lack for patients with ESCC in cli...

    Authors: Qiang Yuan, Yunshu Shi, Yuhan Zhang, Yaqian Shi, Zubair Hussain, Jimin Zhao, Yanan jiang, Yan Qiao, Yaping Guo, Jing Lu, Ziming Dong, Zigang Dong, Junyong Wang and Kangdong Liu
    Citation: Cancer Cell International 2024 24:114
  34. Long non-coding RNAs (lncRNAs) are key regulators of the 6-methyladenosine (m6A) epigenetic modification, playing a role in the initiation and progression of tumors. However, the regulatory mechanisms in head ...

    Authors: Meiting Rong, Ming Zhang, Feihong Dong, Ke Wu, Bingkun Cai, Jinrui Niu, Le Yang, Zhongyan Li and Hui-yi Lu
    Citation: Cancer Cell International 2024 24:113
  35. Gastric cancer (GC) remains a malignant tumor with high morbidity and mortality, accounting for approximately 1,080,000 diagnosed cases and 770,000 deaths worldwide annually. Disulfidptosis, characterized by t...

    Authors: Jie Li, Tian Yu, Juan Sun, Mingwei Ma, Zicheng Zheng, Yixuan He, Weiming Kang and Xin Ye
    Citation: Cancer Cell International 2024 24:112
  36. Gastric cancer is currently estimated to be the fifth leading common cancer in the world, and responsible for about one million new cases and an estimated 769,000 cancer-related deaths each year. WFDC21P is lo...

    Authors: Jinyao Dong, Yongqiang Lv, Debin Meng, Ruyi Shi, Feng Li, Rui Guo, Yi Wang, Jiansheng Guo and Yanyan Zhang
    Citation: Cancer Cell International 2024 24:111

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