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  1. Bladder cancer is the second most common genitourinary malignancy worldwide. The death rate of bladder cancer has increased every year. However, the molecular mechanism of bladder cancer is not sufficiently st...

    Authors: Hui-hui Zhang, An-qi Zhang, Peng Peng, Liang Huang, Cai-ying Liu, Xin-rui Nie, De-fu Hou, Xia Zhang and Shang-ze Li
    Citation: Cancer Cell International 2024 24:32
  2. Hepatocellular carcinoma (HCC) stands as a prevalent malignancy globally, characterized by significant morbidity and mortality. Despite continuous advancements in the treatment of HCC, the prognosis of patient...

    Authors: Lixia Xu, Shu Chen, Qiaoqiao Li, Xinyi Chen, Yuan Xu, Yongjian Zhou, Juan Li, Zhixian Guo, Jiyuan Xing and Di Chen
    Citation: Cancer Cell International 2024 24:30
  3. Platinum-based drugs are cytotoxic drugs commonly used in cancer treatment. They cause DNA damage, effects of which on chromatin and cellular responses are relatively well described. Yet, the nuclear stress re...

    Authors: Enkhzaya Batnasan, Minttu Kärkkäinen, Sonja Koivukoski, Nithin Sadeesh, Sylvain Tollis, Pekka Ruusuvuori, Mauro Scaravilli and Leena Latonen
    Citation: Cancer Cell International 2024 24:29
  4. Primary cell lines are invaluable for exploring cancer biology and investigating novel treatments. Despite their numerous advantages, primary cultures are laborious to obtain and maintain in culture. Hence, es...

    Authors: Oliwia Piwocka, Marika Musielak, Karolina Ampuła, Igor Piotrowski, Beata Adamczyk, Magdalena Fundowicz, Wiktoria Maria Suchorska and Julian Malicki
    Citation: Cancer Cell International 2024 24:28
  5. Breast cancer clinical outcome relies on its intrinsic molecular subtype and mortality is almost exclusively due to metastasis, whose mechanism remains unclear. We recently revealed the specific contribution o...

    Authors: Mauriane Maja, Marie Verfaillie, Patrick Van Der Smissen, Patrick Henriet, Christophe E. Pierreux, Nor Eddine Sounni and Donatienne Tyteca
    Citation: Cancer Cell International 2024 24:27
  6. This review article presents an in-depth analysis of the current state of research on receptor tyrosine kinase regulatory non-coding RNAs (RTK-RNAs) in solid tumors. RTK-RNAs belong to a class of non-coding RN...

    Authors: Aysan Moeinafshar, Mohammad Nouri, Nima Shokrollahi, Mahdi Masrour, Amirmohammad Behnam, Sahand Tehrani Fateh, Hossein Sadeghi, Mohammad Miryounesi and Mohammad-Reza Ghasemi
    Citation: Cancer Cell International 2024 24:26
  7. Cervical cancer (CC) is a potential clinical application of PD-1/PD-L1 inhibitor. We aimed to study the mechanism of DNA mismatch repair (MMR) system regulating the expression of PD-L1 in CC through DNA methyl...

    Authors: Fan Guo, Ruijiao Lu, Weina Kong, Miyessar Anwar and Yangchun Feng
    Citation: Cancer Cell International 2024 24:25
  8. Single nucleotide polymorphisms (SNPs) have been linked with prostate cancer (PCa) and have shown potential as prognostic markers for advanced stages. Loss of function mutations in PKCι have been linked with i...

    Authors: Amna Hafeez, Maria Shabbir, Khushbukhat Khan, Janeen H. Trembley, Yasmin Badshah, Sameen Zafar, Kanza Shahid, Hania Shah, Naeem Mahmood Ashraf, Arslan Hamid, Tayyaba Afsar, Ali Almajwal, Afifa Marium and Suhail Razak
    Citation: Cancer Cell International 2024 24:24
  9. Patients with recurrent or metastatic cervical cancer are in urgent need of novel prognosis assessment or treatment approaches. In this study, a novel prognostic gene signature was discovered by utilizing cupr...

    Authors: Jiawen Kang, Jingwen Jiang, Xiaoqing Xiang, Yong Zhang, Jie Tang and Lesai Li
    Citation: Cancer Cell International 2024 24:23
  10. According to statistics, the incidence of liver cancer is increasing yearly, and effective treatment of liver cancer is imminent. For early liver cancer, resection surgery is currently the most effective treat...

    Authors: Jia-qian Mo, Shen-yan Zhang, Qiang Li, Mo-xian Chen, Yue-qing Zheng, Xin Xie, Rongxin Zhang and Shan-shan Wang
    Citation: Cancer Cell International 2024 24:22
  11. Threonine and tyrosine kinase (TTK) is associated with invasion and metastasis in various tumors. However, the prognostic importance of TTK and its correlation with immune infiltration in endometrial cancer (E...

    Authors: Hongxiang Du, Li Zhang, Jia Chen, Xinyi Chen, Ronghui Qiang, Xiaoyi Ding, Yilang Wang and Xiaoqing Yang
    Citation: Cancer Cell International 2024 24:20
  12. Disulfidptosis is a type of programmed cell death caused by excessive cysteine-induced disulfide bond denaturation leading to actin collapse. Liver cancer has a poor prognosis and requires more effective inter...

    Authors: Jun Tang, Xintong Peng, Desheng Xiao, Shuang Liu, Yongguang Tao and Long Shu
    Citation: Cancer Cell International 2024 24:19
  13. Although non-invasive radiological techniques are widely applied in kidney renal clear cell carcinoma (KIRC) diagnosis, more than 50% of KIRCs are detected incidentally during the diagnostic procedures to iden...

    Authors: Zhenyu Wen, Yingqi Li, Zhengping Zhao, Rongkang Li, Xinji Li, Chong Lu, Chen Sun, Wenkang Chen, Zhenjian Ge, Liangchao Ni and Yongqing Lai
    Citation: Cancer Cell International 2024 24:18
  14. Oleanolic acid (3β-hydroxyolean-12-en-28-oic acid, OA) is a kind of pentacyclic triterpene, which widely distributes in nature. OA possesses a powerful anti-cancer effect; however, its low solubility limits it...

    Authors: Jiaqi Wang, Chuchu Ma, Zhongyuan Tang, Zhengwu Sun, Eskandar Qaed, Xinming Chi, Jun Wang, Yazeed Jamalat, Zhaohong Geng, Zeyao Tang and Qiying Yao
    Citation: Cancer Cell International 2024 24:17
  15. In recent decades, colorectal cancer (CRC) has turned into one of the most widespread malignancies, and the incidence of this malignancy is expected to increase. Despite considerable improvements in therapeuti...

    Authors: Omid Rahbar Farzam, Souzan Najafi, Mohammad Amini, Zohreh Rahimi, Reza Dabbaghipour, Omid Zohdi, Ghazale Asemani Shahgoli, Behzad Baradaran and Bahman Akbari
    Citation: Cancer Cell International 2024 24:16
  16. Metabolic reprogramming, which is recognized as a hallmark of cancer, refers to the phenomenon by which cancer cells change their metabolism to support their increased biosynthetic demands. Tumor cells undergo...

    Authors: Kang Wang, Yan Lu, Haibin Li, Jun Zhang, Yongle Ju and Manzhao Ouyang
    Citation: Cancer Cell International 2024 24:15
  17. Osteosarcoma is one of the most common malignant bone tumors with bad prognosis. Necroptosis is a form of programmed cell death. Recent studies showed that targeting necroptosis was a new promising approach fo...

    Authors: Xiang Li, Zhenqian Sun, Jinlong Ma, Miaomiao Yang, Hongxin Cao and Guangjun Jiao
    Citation: Cancer Cell International 2024 24:14
  18. Glycolysis is critical for harvesting abundant energy to maintain the tumor microenvironment in malignant tumors. Retinoic acid-related orphan receptor α (RORα) has been identified as a circadian gene. However...

    Authors: Xiaoshan Wang, Junyi Zhang, Yuwei Wu, Yuqing Zhang, Siyuan Zhang, Angqing Li, Jian Wang and Zhengguang Wang
    Citation: Cancer Cell International 2024 24:12
  19. Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase integral to the regulation of many cellular processes. Due to the deregulation of PP2A in cancer, many of these processes are turned toward promo...

    Authors: Hannah Johnson, Satya Narayan and Arun K. Sharma
    Citation: Cancer Cell International 2024 24:11
  20. In the Modern era, immune checkpoint inhibitors (ICIs) have been the cornerstone of success in the treatment of several malignancies. Despite remarkable therapeutic advances, complex matrix together with signi...

    Authors: Maryam Noori, Farideh Jafari-Raddani, Zeinab Davoodi-Moghaddam, Mahda Delshad, Saeid Safiri and Davood Bashash
    Citation: Cancer Cell International 2024 24:10
  21. Hepatocellular carcinoma (HCC) is the most prevalent form of liver cancer, with a high mortality rate and poor prognosis. Mutated or dysregulated transcription factors (TFs) are significantly associated with c...

    Authors: Meixia Wang, Hanyao Guo, Bo Zhang, Yanan Shang, Sidi Zhang, Xiaoyu Liu, Pengxiu Cao, Yumei Fan and Ke Tan
    Citation: Cancer Cell International 2024 24:9
  22. Despite advancements in treating metastatic melanoma, many patients exhibit resistance to targeted therapies. Our study focuses on ATP1A1, a sodium pump subunit associated with cancer development. We aimed to ...

    Authors: Laura Soumoy, Aline Genbauffe, Lena Mouchart, Alexandra Sperone, Anne Trelcat, Léa Mukeba-Harchies, Mathilde Wells, Bertrand Blankert, Ahmad Najem, Ghanem Ghanem, Sven Saussez and Fabrice Journe
    Citation: Cancer Cell International 2024 24:8
  23. The high invasiveness and infiltrative nature of Glioblastoma (GBM) pose significant challenges for surgical removal. This study aimed to investigate the role of KCNA1 in GBM progression.

    Authors: Weichao Wang, Yang Zhang, Xuetao Li, Qinzi E, Zuoyu Jiang, Qikun Shi, Yu Huang, Jian Wang and Yulun Huang
    Citation: Cancer Cell International 2024 24:7
  24. The tumor microenvironment and cancer-associated fibroblasts (CAFs) play crucial roles in tumor development, and their metabolic coupling remains unclear. Clinical data showed a positive correlation between PD...

    Authors: Jianguo Xu, Li Bian, Dingyun You, Ziliang Li, Tingting Wang, Yiting Li, Xiaobin Ren and Yongwen He
    Citation: Cancer Cell International 2024 24:5
  25. Cancer stem cells (CSCs) play a pivotal role in the pathogenesis of human cancers. Previous studies have highlighted the role of long non-coding RNA (lncRNA) in modulating the stemness of CSCs. In our investig...

    Authors: Liu Ouyang, Min-min Sun, Ping-sheng Zhou, Yi-wei Ren, Xin-yu Liu, Wan-ying Wei, Zhen-shun Song, Kai Lu and Li-xue Yang
    Citation: Cancer Cell International 2024 24:4
  26. The alterations of RNA profile in tumor-educated platelets (TEPs) have been described as a novel biosource for cancer diagnostics. This study aimed to explore the potential snoRNAs in TEP as biomarkers for dia...

    Authors: Xuan Zhao, Guanxuan Chen, Yawen Wu, Xiao Li, Zhe Zhang, Li Xie, Xianrang Song and Xingguo Song
    Citation: Cancer Cell International 2024 24:3
  27. Disulfidptosis is a recently proposed novel cell death mode in which cells with high SLC7A11 expression induce disulfide stress and cell death in response to glucose deficiency. The purpose of the research was to...

    Authors: Leqi Zhong, Wuguang Chang, Bin Luo, Wuyou Gao, Huanhuan He, Mouxiang Fang, Hongmu Li, Zhesheng Wen and Youfang Chen
    Citation: Cancer Cell International 2024 24:2
  28. Liver cancer is one of the most common cancers in the world and a primary cause of cancer-related death. In recent years, despite the great development of diagnostic methods and targeted therapies for liver ca...

    Authors: Qiaoping Xu, Ning Ren, Lanqi Ren, Yibei Yang, Junjie Pan and Hongkai Shang
    Citation: Cancer Cell International 2024 24:1
  29. Green tea, a popular and healthy nonalcoholic drink consumed globally, is abundant in natural polyphenols. One of these polyphenols is epigallocatechin-3-gallate (EGCG), which offers a range of health benefits...

    Authors: Guichun Wang, Jinyi Wang and Mohammad Reza Momeni
    Citation: Cancer Cell International 2023 23:335
  30. Circular RNAs (circRNAs) are a class of noncoding RNAs that are involved in the progression of many human cancers. The precise gene locus and the roles of circular RNA from Fibronectin type III domain containi...

    Authors: Congya Li, Linchao Ding, Xuyao Wang, Peng Shu, Xuchao Shi, Zhijian Zheng, Jian Liu and Junlan Zhu
    Citation: Cancer Cell International 2023 23:334
  31. DPY30 belongs to the core subunit of components of the histone lysine methyltransferase complex, which is implicated in tumorigenesis, cell senescence, and other biological events. However, its contribution to...

    Authors: Chun-Ying Luo, Wei-Chao Su, Hai-Feng Jiang, Ling-Tao Luo, Dong-Yan Shen and Guo-Qiang Su
    Citation: Cancer Cell International 2023 23:333
  32. Increasing evidence highlights the potential role of long non-coding RNAs (lncRNAs) in the biological behaviors of renal cell carcinoma (RCC). Here, we explored the mechanism of AGAP2-AS1 in the occurrence and...

    Authors: Peng Xu, Da-xiong Feng, Jun Wang, Yao-Dong Wang, Gang Xie, Bin Zhang, Xiao-Han Li, Jia-Wei Zeng and Jia-Fu Feng
    Citation: Cancer Cell International 2023 23:330
  33. Cervical cancer is a leading cause of gynecological cancer death in the world. Human papillomavirus (HPV) is the most causative factor of cervical cancer. In addition, many genetic factors are involved in cerv...

    Authors: Li Li, Yixin Tong, Jianhong Wu and Xiangshang Xu
    Citation: Cancer Cell International 2023 23:329
  34. Chimeric antigen receptor (CAR) T-cells have revolutionized the treatment of CD19- and B-cell maturation antigen-positive haematological malignancies. However, the effect of a CAR construct on the function of ...

    Authors: Gerard J. Chu, Charles G. Bailey, Rajini Nagarajah, Sharon M. Sagnella, Stephen Adelstein and John E. J. Rasko
    Citation: Cancer Cell International 2023 23:327
  35. Fibroblasts, especially cancer-associated fibroblasts (CAFs), represent the predominant stromal cell population in the tumor microenvironment and have an important function in tumorigenesis by interacting with...

    Authors: Wei Cheng, Yonghui Liao, Yuan Xie, Qinrong Wang, Leilei Li, Yuanjia Chen, Yan Zhao and Jianjiang Zhou
    Citation: Cancer Cell International 2023 23:326
  36. Melanoma, a severe form of skin cancer, poses significant health risks due to its aggressive nature and potential for metastasis. The role of two-pore channel 2 (TPC2) in the development and progression of mel...

    Authors: Ali Hanbashi, Moureq Alotaibi, Homood M. As Sobeai, Lama Binobaid, Khalid Alhazzani, Xuhui Jin, Faroq Kamli, Ali Alhoshani and John Parrington
    Citation: Cancer Cell International 2023 23:325
  37. There has been a growing global interest in the potential health benefits of edible natural bioactive products in recent years. Ganoderma lucidum, a medicinal mushroom, has gained attention for its decadent array...

    Authors: Xiaoli Gao and Mina Homayoonfal
    Citation: Cancer Cell International 2023 23:324
  38. Breast cancer is the leading cause of cancer death for women worldwide. Most of the breast cancer death are due to disease recurrence and metastasis. Increasingly accumulating evidence indicates that mitochond...

    Authors: Yang Wang, Jieyi Wang, Lan Chen, Zhuo Chen, Tong Wang, Shuting Xiong, Tong Zhou, Guang Wu, Licai He, Jiawei Cao, Min Liu, Hongzhi Li and Haihua Gu
    Citation: Cancer Cell International 2023 23:323
  39. Lung cancer is the leading cause of cancer-related death. Lysosomes are key degradative compartments that maintain protein homeostasis. In current study, we aimed to construct a lysosomes-related genes signatu...

    Authors: Dingli Song, Lili Zhao, Guang Zhao, Qian Hao, Jie Wu, Hong Ren and Boxiang Zhang
    Citation: Cancer Cell International 2023 23:322
  40. Artificial intelligence (AI) is capable of integrating a large amount of related information to predict therapeutic relationships such as disease treatment with known drugs, gene expression, and drug-target bi...

    Authors: Na Ly Tran, Hyerim Kim, Cheol-Hee Shin, Eun Ko and Seung Ja Oh
    Citation: Cancer Cell International 2023 23:321
  41. Colorectal neoplasms are one of the deadliest diseases among all cancers worldwide. Thymoquinone (TQ) is a natural compound of Nigella sativa that has been used in traditional medicine against a variety of acute/...

    Authors: Farhad Sheikhnia, Vahid Rashidi, Hossein Maghsoudi and Maryam Majidinia
    Citation: Cancer Cell International 2023 23:320
  42. CD56 has been observed in malignant tumours exhibiting neuronal or neuroendocrine differentiation, such as breast cancer, small-cell lung cancer, and neuroblastoma. Abnormal glycosylation modifications are tho...

    Authors: Yuli Jian, Lin Zhang, Li Gong, Mengting Ding, Xiaoxin Sun, Xiao Yu, Shaohui Lv, Jinjing Li, Deyong Yang and Shujing Wang
    Citation: Cancer Cell International 2023 23:319
  43. Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year survival rate varies widely from 4 to 60%, mainly due t...

    Authors: Francisco Rodas, Jetzabel A. Vidal-Vidal, Daniela Herrera, David A. Brown-Brown, Diego Vera, Joaquín Veliz, Pilar Püschel, José I. Erices, Verónica Sánchez Hinojosa, Julio C. Tapia, Eduardo Silva-Pavez, Claudia Quezada-Monrás, Pablo Mendoza-Soto, Flavio Salazar-Onfray, Cristian Carrasco and Ignacio Niechi
    Citation: Cancer Cell International 2023 23:318

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