Skip to main content

Advertisement

Articles

Page 2 of 31

  1. The study aimed to explore the associations between the interactions of serum vitamin B2 or B12 levels, aberrant DNA methylation of p16 or p53 and MTHFR C677T polymorphism and the risks of esophageal squamous cel...

    Authors: Da Pan, Ming Su, Guiling Huang, Pengfei Luo, Ting Zhang, Lingmeng Fu, Jie Wei, Shaokang Wang and Guiju Sun

    Citation: Cancer Cell International 2019 19:288

    Content type: Primary research

    Published on:

  2. Both cell adhesion and matrix metalloproteinase (MMP) activity depend on pH at the cell surface. By regulating extracellular juxtamembrane pH, the Na+/H+ exchanger NHE1 plays a significant part in human melanoma ...

    Authors: Dennis Keurhorst, Ivan Liashkovich, Fabian Frontzek, Svenja Nitzlaff, Verena Hofschröer, Rita Dreier and Christian Stock

    Citation: Cancer Cell International 2019 19:285

    Content type: Primary research

    Published on:

  3. Tripartite motif-containing protein 11 (TRIM11), a member of RING family of E3 ubiquitin ligases, is identified as an oncogene in certain human tumors. However, the detailed biological function of TRIM11 in ch...

    Authors: Bin Wang, Gang Wang, Qingfeng Wang, Ziqiang Zhu, Yunqing Wang, Kangwu Chen and Huilin Yang

    Citation: Cancer Cell International 2019 19:284

    Content type: Primary research

    Published on:

  4. Tripartite motif‑containing 27 (TRIM27) belongs to the TRIM protein family, which is closely related to the progression of some certain human cancers. Nevertheless, the biological function of TRIM27 in esophag...

    Authors: Liang Ma, Ninghua Yao, Ping Chen and Zhixiang Zhuang

    Citation: Cancer Cell International 2019 19:283

    Content type: Primary research

    Published on:

  5. Angiogenesis plays critical roles in the progression and metastasis of malignant tumors. Gastric neuroendocrine carcinoma is an uncommon stomach cancer that is rich in blood vessels and exhibits highly maligna...

    Authors: Jian-Xian Lin, Xiong-Feng Weng, Xin-Sheng Xie, Ning-Zi Lian, Sheng-Liang Qiu, Jia-Bin Wang, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Ying-Hong Yang, Si-Jia Liu, Min Hu, Yi-Ke Lin, Chang-Ming Huang…

    Citation: Cancer Cell International 2019 19:282

    Content type: Primary research

    Published on:

  6. Recently, the impact of microRNAs (miRNAs) and exosome on ovarian cancer has been assessed in many studies. We aim to explore the mechanism of exosomes transferring miR-205 in ovarian cancer, and confirm its d...

    Authors: Lijun Wang, Fei Zhao, Zhongqing Xiao and Liang Yao

    Citation: Cancer Cell International 2019 19:281

    Content type: Primary research

    Published on:

  7. Glioma is the most common central nervous system (CNS) tumour. p62, an important autophagy adaptor, plays a crucial role in cancer. However, the role of p62 in the progression of glioma is poorly characterized.

    Authors: Danni Deng, Kaiming Luo, Hongmei Liu, Xichen Nie, Lian Xue, Rong Wang, Yuan Xu, Jun Cui, Naiyuan Shao and Feng Zhi

    Citation: Cancer Cell International 2019 19:280

    Content type: Primary research

    Published on:

  8. Radiation sensitive 52 (RAD52) is an important protein that mediates DNA repair in tumors. However, little is known about the impact of RAD52 on hepatocellular carcinoma (HCC). We investigated the expression o...

    Authors: Ping Li, YanZhen Xu, Qinle Zhang, Yu Li, Wenxian Jia, Xiao Wang, Zhibin Xie, Jiayi Liu, Dong Zhao, Mengnan Shao, Suixia Chen, Nanfang Mo, Zhiwen Jiang, Liuyan Li, Run Liu, Wanying Huang…

    Citation: Cancer Cell International 2019 19:279

    Content type: Primary research

    Published on:

  9. Long noncoding RNAs (lncRNAs) are involved in different pathogenesis pathways including cancer pathogenesis. The adenoma-carcinoma pathway in colorectal cancer may involve the aberrant and variable gene expres...

    Authors: Milad Shademan, Azam Naseri Salanghuch, Khadijeh Zare, Morteza Zahedi, Mohammad Ali Foroughi, Kambiz Akhavan Rezayat, Hooman Mosannen Mozaffari, Kamran Ghaffarzadegan, Ladan Goshayeshi and Hesam Dehghani

    Citation: Cancer Cell International 2019 19:278

    Content type: Primary research

    Published on:

  10. CKS1 is highly expressed in colon cancer tissues, and is essential for cancer cell proliferation. The downstream molecular mechanism of CKS1 has been fully studied, but the upstream regulatory mechanism of it ...

    Authors: Zhengbin Chai, Li Wang, Yabing Zheng, Na Liang, Xiwei Wang, Yingying Zheng, Zhiwei Zhang, Chuanxi Zhao, Tingting Zhu and Chunyan Liu

    Citation: Cancer Cell International 2019 19:277

    Content type: Primary research

    Published on:

  11. The long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) is involved in various cancers and often functions through microRNAs. The pro-survival protein PTP1B is known to play important roles i...

    Authors: Yi Li, Qingan Zeng, Jiliang Qiu, Ting Pang, Jianzhong Xian and Xuexia Zhang

    Citation: Cancer Cell International 2019 19:275

    Content type: Primary research

    Published on:

  12. Daily experience tells us that breast cancer can be controlled using standard protocols up to the advent of a relapse. Now new frontiers in precision medicine like liquid biopsy of cell free DNA (cfDNA) give u...

    Authors: Maria Palmieri, Margherita Baldassarri, Francesca Fava, Alessandra Fabbiani, Giuseppe Maria Campennì, Maria Antonietta Mencarelli, Rossella Tita, Stefania Marsili, Alessandra Renieri and Elisa Frullanti

    Citation: Cancer Cell International 2019 19:274

    Content type: Commentary

    Published on:

  13. This study is performed to investigate the effects of adenovirus-mediated X-linked inhibitor of apoptosis protein (XIAP) overexpressed bone marrow mesenchymal stem cells (BMSCs) on brain injury in rats with ce...

    Authors: Wenjing Deng, Chenghe Fan, Yanbo Fang, Yanan Zhao, Yamin Wei, Meng Li and Junfang Teng

    Citation: Cancer Cell International 2019 19:273

    Content type: Primary research

    Published on:

  14. To investigate the value of dynamic monitoring peripheral blood lymphocyte-to-monocyte (LMR) ratio in evaluating the treatment response and prognosis of patients with extranodal NK/T cell lymphoma (ENKTL).

    Authors: Shengnan Zhang, Mengjuan Li, Fangfang Yuan, Lin Chen, Ruihua Mi, Xudong Wei, Yongping Song and Qingsong Yin

    Citation: Cancer Cell International 2019 19:272

    Content type: Review

    Published on:

  15. Prostate cancer (PCa) is a common disease that often occurs among older men and a frequent cause of malignancy associated death in this group. microRNA (miR)-129-5p has been identified as an essential regulato...

    Authors: Zhenming Jiang, Yuxi Zhang, Xi Chen, Pingeng Wu and Dong Chen

    Citation: Cancer Cell International 2019 19:271

    Content type: Primary research

    Published on:

  16. LncRNAs may exert a regulatory effect in tumorigenesis. Although the expression of lncRNA HOTAIR has been confirmed to be notably elevated in the tissues of CSCC, its biological mechanism in CSCC is still unknown...

    Authors: Guo-Jun Yu, Yong Sun, Da-Wei Zhang and Peng Zhang

    Citation: Cancer Cell International 2019 19:270

    Content type: Primary research

    Published on:

  17. Malignant glioma is one of the essentially incurable tumors with chemoresistance and tumor recurrence. As a histone methyltransferase, SUV39H2 can trimethylate H3K9. SUV39H2 is highly expressed in many types o...

    Authors: Ran Wang, Lilin Cheng, Xi Yang, Xin Chen, Yifeng Miao, Yongming Qiu and Zhiyi Zhou

    Citation: Cancer Cell International 2019 19:269

    Content type: Primary research

    Published on:

  18. Circular RNAs (circRNAs) are involved in regulating tumor pathogenesis. The mechanism of circRNAs in gastric cancer (GC) is still unknown. Our study aimed to identify differentially expressed circRNAs and asse...

    Authors: Jianming Wei, Jinmiao Wang, Xibo Gao and Feng Qi

    Citation: Cancer Cell International 2019 19:268

    Content type: Primary research

    Published on:

  19. Many circRNAs have been reported to play important roles in cancer development and have the potential to serve as a novel class of biomarkers for clinical diagnosis. However, the role of circRNAs in esophageal...

    Authors: Rongrong Zhong, Zhuozhi Chen, Ting Mo, Zimo Li and Peng Zhang

    Citation: Cancer Cell International 2019 19:267

    Content type: Primary research

    Published on:

  20. Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related death worldwide. The inhibition of epidermal growth factor receptor (EGFR) signaling by tyrosine kinase inhibitors or monoclonal antibo...

    Authors: Jing Wang, Peiyuan Sun, Qi Wang, Pan Zhang, Yuna Wang, Chengting Zi, Xuanjun Wang and Jun Sheng

    Citation: Cancer Cell International 2019 19:266

    Content type: Primary research

    Published on:

  21. Tumor-infiltrating immune cells (TIICs) are highly relevant to clinical outcome of glioma. However, previous studies cannot account for the diverse functions that make up the immune response in malignant trans...

    Authors: Jiacheng Lu, Hailin Li, Zhengxin Chen, Ligang Fan, Shuang Feng, Xiaomin Cai and Huibo Wang

    Citation: Cancer Cell International 2019 19:265

    Content type: Primary research

    Published on:

  22. Centromere Protein F (CENPF) associates with the centromere–kinetochore complex and influences cell proliferation and metastasis in several cancers. The role of CENPF in breast cancer (BC) bone metastasis rema...

    Authors: Jingbo Sun, Jingzhan Huang, Jin Lan, Kun Zhou, Yuan Gao, Zhigao Song, Yunyao Deng, Lixin Liu, Ying Dong and Xiaolong Liu

    Citation: Cancer Cell International 2019 19:264

    Content type: Primary research

    Published on:

  23. Triple-negative breast carcinoma (TNBC) patients do not benefit from hormone- or human epidermal growth factor receptor 2- (HER2-) targeted therapies. Accurate testing is pivotal for these patients.

    Authors: Jose De Jesus and Marilin Rosa

    Citation: Cancer Cell International 2019 19:263

    Content type: Primary research

    Published on:

  24. Pancreatic cancer is a malignancy with a very poor prognosis. The emergence of liquid biopsy is expected to achieve accurate early diagnosis through detection of tumor-derived secreted proteins in the blood. E...

    Authors: Peng Liu, Lingming Kong, Haoyi Jin, Yunhao Wu, Xiaodong Tan and Bing Song

    Citation: Cancer Cell International 2019 19:262

    Content type: Primary research

    Published on:

  25. Cancer has been a worldwide health problem with a high risk of morbidity and mortality, however ideal biomarkers for effective screening and diagnosis of cancer patients are still lacking. Small nucleolar RNA ...

    Authors: Chenghao Zhang, Xiaolei Ren, Jieyu He, Wanchun Wang, Chao Tu and Zhihong Li

    Citation: Cancer Cell International 2019 19:261

    Content type: Primary research

    Published on:

  26. The glial cells of the primary olfactory nervous system, olfactory ensheathing cells (OECs), are unusual in that they rarely form tumors. Only 11 cases, all of which were benign, have been reported to date. In...

    Authors: Mariyam Murtaza, Anu Chacko, Ali Delbaz, Ronak Reshamwala, Andrew Rayfield, Brent McMonagle, James A. St John and Jenny A. K. Ekberg

    Citation: Cancer Cell International 2019 19:260

    Content type: Review

    Published on:

  27. Serum/plasma YKL-40 can be a useful index that is associated with tumor development. However, the prognostic value of serum/plasma YKL-40 in patients with solid tumors is still unclear. We aimed to utilize the...

    Authors: Bingxian Bian, Li Li, Junyao Yang, Yi Liu, Guohua Xie, Yingxia Zheng, Liang Zeng, Junxiang Zeng and Lisong Shen

    Citation: Cancer Cell International 2019 19:259

    Content type: Primary research

    Published on:

  28. This study is conducted to investigate the effect of lncRNA PIK3CD-AS1 on the growth and metastasis of hepatocellular carcinoma (HCC) and its potential mechanism.

    Authors: Wei Song, Jingjing Zhang, Jianbo Zhang, Miaomiao Sun and Qingxin Xia

    Citation: Cancer Cell International 2019 19:150

    Content type: Primary research

    Published on:

  29. Non-small-cell lung cancer (lung cancer) has become one of the leading causes worldwide and the underlying mechanism is not fully understood. The transcriptional factor Kruppel like factor 8 (KLF8) is involved...

    Authors: Dongjie Ma, Hongsheng Liu, Yingzhi Qin, Zhenhuan Tian, Shanqing Li and Naixin Liang

    Citation: Cancer Cell International 2019 19:258

    Content type: Primary research

    Published on:

  30. miRNAs, a major class of small noncoding RNAs approximately 18–25 nucleotides in length, function by repressing the expression of target genes through binding to complementary sequences in the 3′-UTRs of targe...

    Authors: Yue Yu and Xu-Chen Cao

    Citation: Cancer Cell International 2019 19:257

    Content type: Review

    Published on:

  31. A hallmark of acute promyelocytic leukemia (APL) is the expression of PML/RARα fusion protein. Treatment with all-trans retinoic acid (ATRA) results in the terminal differentiation of neutrophil granulocytes. ...

    Authors: Xinrui Wang, Huiyong Fan, Congling Xu, Guojuan Jiang, Haiwei Wang and Ji Zhang

    Citation: Cancer Cell International 2019 19:256

    Content type: Primary research

    Published on:

  32. Hepatocellular carcinoma (HCC), the most common primary cancer of the liver, is one of the most common malignancies and the leading cause of cancer-related death worldwide. Leucine-rich repeat and sterile alph...

    Authors: Lili Pian, Xiaofeng Huang, Min Zhao, Yaolin Zhang, Cheng Qin, Jiyan Zhang, Jun Zhang and Qingyang Wang

    Citation: Cancer Cell International 2019 19:255

    Content type: Primary research

    Published on:

  33. Extracellular ATP (eATP) was shown to induce epithelial–mesenchymal transition (EMT), a very important early process in metastasis, in cancer cells via purinergic receptor signaling. However, the exact inducti...

    Authors: Yanyang Cao, Xuan Wang, Yunsheng Li, Maria Evers, Haiyun Zhang and Xiaozhuo Chen

    Citation: Cancer Cell International 2019 19:254

    Content type: Primary research

    Published on:

  34. Phosphoglucomutase (PGM), a key enzyme in the metabolism of glucose-1-phosphate and glucose-6-phosphate, has been found to be associated with proliferation, invasion, and metastasis of cancer. However, the exp...

    Authors: Yifan Sun, Haihua Long, Lin Sun, Xiujuan Sun, Liping Pang, Jianlin Chen, Qingqun Yi, Tianwei Liang and Yongqi Shen

    Citation: Cancer Cell International 2019 19:253

    Content type: Primary research

    Published on:

  35. Circular RNA (circRNA) CDR1as plays an important role in the occurrence and development of human tumors. The purpose of this study is to investigate the molecular mechanism of circRNA CDR1as in the development...

    Authors: Qiong Zhong, Juncong Huang, Jiawang Wei and Renrui Wu

    Citation: Cancer Cell International 2019 19:252

    Content type: Primary research

    Published on:

  36. Exosomal nucleic acid (exoNA) is a feasible target to improve the sensitivity of EGFR mutation testing in non-small cell lung cancer patients with limited cell-free DNA (cfDNA) mutant copies. However, the type an...

    Authors: Yoonjung Kim, Saeam Shin, Boyeon Kim and Kyung-A Lee

    Citation: Cancer Cell International 2019 19:251

    Content type: Primary research

    Published on:

  37. Esophageal squamous cell carcinoma (ESCC) is the eighth most common cancer worldwide and is one of the most lethal malignancies. Cisplatin (DDP) is a key drug for ESCC treatment, but the presence of chemothera...

    Authors: Tian-Liang Zheng, De-Ping Li, Zhan-Feng He and Song Zhao

    Citation: Cancer Cell International 2019 19:250

    Content type: Primary research

    Published on:

  38. Hepatocellular carcinoma (HCC) is the second-most lethal cancer worldwide with a complex pathogenesis. RuvB-like 2 (RUVBL2) was previously found to contribute to hepatocarcinogenesis. However, its expression, ...

    Authors: Tao Yan, Fang Liu, Jiajia Gao, Haizhen Lu, Jianqiang Cai, Xiaohang Zhao and Yulin Sun

    Citation: Cancer Cell International 2019 19:249

    Content type: Primary research

    Published on:

  39. Neuropilin-1 (NRP-1) is a non-tyrosine kinase receptor interacting with multiple signaling pathways that underpin the biological behavior and fate of cancer cells. However, in pancreatic cancer, the mechanisms...

    Authors: Lixin Ma, Bo Zhai, Huaqiang Zhu, Weidong Li, Wenjing Jiang, Liwang Lei, Shujun Zhang, Haiquan Qiao, Xian Jiang and Xueying Sun

    Citation: Cancer Cell International 2019 19:248

    Content type: Primary research

    Published on:

  40. CD146 alternatively called melanoma cell adhesion molecule (MCAM), is a biomarker and therapeutic target of clinical significance. It is found on different cells including the endothelial cells and lymphocytes...

    Authors: Ayobami Matthew Olajuyin, Adefunke Kafayat Olajuyin, Ziqi Wang, Xingru Zhao and Xiaoju Zhang

    Citation: Cancer Cell International 2019 19:247

    Content type: Review

    Published on:

  41. Recently, some studies reported the prognostic value of platelet-to-lymphocyte ratio (PLR) in patients with diffuse large B-cell lymphoma (DLBCL), however, the results varied from different studies. Therefore,...

    Authors: Ying Chen, Zongxin Zhang, Qiu Fang and Huiqin Jian

    Citation: Cancer Cell International 2019 19:245

    Content type: Primary research

    Published on:

  42. Following publication of the original article [1], it has been brought to our attention that an incorrect Sequenom MassArray trace and an incorrect nomenclature were used to represent the PIK3CA p.E545A mutati...

    Authors: Matteo Fassan, Luca Vianello, Diana Sacchi, Giuseppe N. Fanelli, Giada Munari, Marco Scarpa, Rocco Cappellesso, Fotios Loupakis, Cristiano Lanza, Roberta Salmaso, Claudia Mescoli, Nicola Valeri, Marco Agostini, Edoardo D’Angelo, Sara Lonardi, Salvatore Pucciarelli…

    Citation: Cancer Cell International 2019 19:244

    Content type: Correction

    Published on:

    The original article was published in Cancer Cell International 2018 18:131

  43. The hypoxic tumor microenvironment accelerates the invasion and migration of colorectal cancer (CRC) cells. The aim of this study was to develop and validate a hypoxia gene signature for predicting the outcome...

    Authors: Yi-feng Zou, Yu-ming Rong, Ying-xin Tan, Jian Xiao, Zhao-liang Yu, Yu-feng Chen, Jia Ke, Cheng-hang Li, Xi Chen, Xiao-jian Wu, Ping Lan, Xu-tao Lin and Feng Gao

    Citation: Cancer Cell International 2019 19:243

    Content type: Primary research

    Published on:

  44. Triple negative breast cancer (TNBC) is a breast cancer (BC) subtype that is characterized by its strong invasion and a high risk of metastasis. However, the specific mechanisms underlying these phenotypes are...

    Authors: Weiguang Liu, Jianjun Han, Sufang Shi, Yuna Dai and Jianchao He

    Citation: Cancer Cell International 2019 19:242

    Content type: Primary research

    Published on:

  45. Persistent infection with high-risk human papillomavirus (hrHPV) is associated with cervical cancer development. This process involves the virus-encoded E6 and E7 oncoproteins, which are maintained and express...

    Authors: Chao Li, Yanfei Li, Lanxia Sui, Jian Wang and Fang Li

    Citation: Cancer Cell International 2019 19:241

    Content type: Primary research

    Published on:

  46. Long non-coding RNAs (lncRNAs) are a family of non-protein-coding RNAs, which have the ability to influence the chemo-resistance of lung adenocarcinoma (LAC). In this study, we explored the mechanism by which ...

    Authors: Wei Zuo, Wei Zhang, Fei Xu, Jing Zhou and Wei Bai

    Citation: Cancer Cell International 2019 19:240

    Content type: Primary research

    Published on:

  47. Lung cancer has been a common malignant tumor with a leading cause of morbidity and mortality, current molecular targets are woefully lacking comparing to the highly progressive cancer. The study is designed t...

    Authors: Wenxia Ma, Bin Wang, Yaping Zhang, Ziyue Wang, Dan Niu, Siyu Chen, Zhirong Zhang, Ningning Shen, Weixia Han, Xiaoqin Zhang, Rong Wei and Chen Wang

    Citation: Cancer Cell International 2019 19:239

    Content type: Primary research

    Published on:

  48. Avoiding the phagocytosis by tumor-associated macrophages (TAMs) is necessary for the growth and metastasis of solid tumors. CD47 binds to the receptor signal-regulatory protein-α (SIRP-α) on the macrophages t...

    Authors: Jingping Yuan, Huihua He, Chuang Chen, Juan Wu, Jie Rao and Honglin Yan

    Citation: Cancer Cell International 2019 19:238

    Content type: Primary research

    Published on:

Annual Journal Metrics

On the blog

Institutional membership

Visit the membership page to check if your institution is a member and learn how you could save on article-processing charges (APCs).

Funding your APC

​​​​​​​Open access funding and policy support by SpringerOpen​​

​​​​We offer a free open access support service to make it easier for you to discover and apply for article-processing charge (APC) funding. Learn more here

Advertisement