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  1. SWI/SNF, a well-known ATP-dependent chromatin-remodeling complex, plays an essential role in several biological processes. SNF5, the core subunit of the SWI/SNF remodeling complex, inactivated in 95% of malign...

    Authors: Hua Ding, Yaqin Huang, Jiazhong Shi, Liwei Wang, Sha Liu, Baixiong Zhao, Yuting Liu, Jin Yang and Zhiwen Chen
    Citation: Cancer Cell International 2021 21:655

    The Correction to this article has been published in Cancer Cell International 2022 22:20

  2. Tumor migration and invasion is a complex and diverse process that involves the epithelial–mesenchymal transition (EMT) of tumor cells and degradation of the extracellular matrix by matrix metalloproteases (MM...

    Authors: Mengying Teng, Chunyan Hu, Bingmo Yang, Wei Xiao, Qian Zhou, Yuan Li and Zhong Li
    Citation: Cancer Cell International 2021 21:654
  3. Aging and senescence can alter immune cell fitness and influence the efficacy of lung cancer treatments, especially immunotherapy. However, the correlations between cellular senescence and tumor microenvironme...

    Authors: Weihao Lin, Xin Wang, Zhenyi Xu, Zhen Wang, Tiejun Liu, Zheng Cao, Xiaoli Feng, Yibo Gao and Jie He
    Citation: Cancer Cell International 2021 21:652
  4. Circular RNAs (circRNAs) act pivotal roles in the progression of multiple malignancies. However, the underlying mechanisms by which hsa_circ_0007031 (circTUBGCP3) contributes to lung adenocarcinoma (LAC) remai...

    Authors: Yang Yang, Xin Fan, Yunfei Nie, Donglei Liu, Dengyan Zhu, Kai Wu, Yuan Zhang, Wenhua Li, Xiangyu Tian, Huaqi Wang and Yuxia Fan
    Citation: Cancer Cell International 2021 21:651
  5. Previous studies indicated CRNDE to have a pivotal part within tumorigenesis. Notwithstanding, precise details on CRNDE activities within NPC are still uncertain. The investigation described in this article se...

    Authors: Sichen Ge, Chengyi Jiang, Min Li, Zhongqiang Cheng and Xiaojia Feng
    Citation: Cancer Cell International 2021 21:650
  6. The ESR1 gene suffers methylation changes in many types of cancers, including breast cancer (BC), the most frequently diagnosed cancer in women that is also present in men. Methylation at promoter A of ESR1 is th...

    Authors: Laura Itzel Quintas-Granados, Hernán Cortés, Manuel González-Del Carmen, Gerardo Leyva-Gómez, Lilia Patricia Bustamante-Montes, Miguel Rodríguez-Morales, Edgar Yebran Villegas-Vazquez, Israel López-Reyes, Sofía Lizeth Alcaraz-Estrada, Jorge Sandoval-Basilio, Ernesto Soto-Reyes, Javad Sharifi-Rad, Gabriela Figueroa-González and Octavio Daniel Reyes-Hernández
    Citation: Cancer Cell International 2021 21:649
  7. Osteosarcoma (OS) patients with lung metastasis have poor prognoses, and effective therapeutic strategies for delaying or inhibiting the spread of lung metastasis from the primary OS site are lacking. Hence, i...

    Authors: Haoran Kong, Wenhui Yu, Zhuning Chen, Haonan Li, Guiwen Ye, Jiacong Hong, Zhongyu Xie, Keng Chen, Yanfeng Wu and Huiyong Shen
    Citation: Cancer Cell International 2021 21:648

    The Correction to this article has been published in Cancer Cell International 2022 22:152

  8. Eribulin has shown antitumour activity in some soft tissue sarcomas (STSs), but it has only been approved for advanced liposarcoma (LPS).

    Authors: Javier Escudero, Victoria Heredia-Soto, Yinyin Wang, Patricia Ruiz, Yingying Hu, Alejandro Gallego, Jose Juan Pozo-Kreilinger, Virginia Martinez-Marin, Alberto Berjon, Eduardo Ortiz-Cruz, Daniel Bernabeu, Jaime Feliu, Jing Tang, Andres Redondo and Marta Mendiola
    Citation: Cancer Cell International 2021 21:646
  9. Glioma is a common type of malignant brain tumor with a high mortality and relapse rate. The endosomal sorting complex required for transport (ESCRT) has been reported to be involved in tumorigenesis. However,...

    Authors: Xiaolong Zhu, Hui Yang, Mengying Zhang, Xingwei Wu, Lan Jiang, Xiaocen Liu and Kun Lv
    Citation: Cancer Cell International 2021 21:645
  10. The lncRNA H19 is believed to act as an oncogene in various types of tumors and is considered to be a therapeutic target and diagnostic marker. However, the role of the lncRNA H19 in regulating the radiosensit...

    Authors: Xueshan Zhao, Xiaodong Jin, Qiuning Zhang, Ruifeng Liu, Hongtao Luo, Zhen Yang, Yichao Geng, Shuangwu Feng, Chengcheng Li, Lina Wang, Xiaohu Wang and Qiang Li
    Citation: Cancer Cell International 2021 21:644
  11. Human papillomavirus (HPV) E6/E7 mRNA in situ hybridization (HPV E6/E7 RNAscope) appears to be a sensitive and specific technique in detecting transcriptionally active HPV. We aimed to examine the diagnostic u...

    Authors: Rong-Zhen Luo, Shu-Lin Chen, Mei Li, Yue Li, Xia Yang and Li-Li Liu
    Citation: Cancer Cell International 2021 21:643
  12. Heterogeneous nuclear ribonucleoprotein K (HnRNPK) is a nucleic acid-binding protein that regulates diverse biological events. Pathologically, HnRNPK proteins are frequently overexpressed and clinically correl...

    Authors: Huan-Lei Wu, Sen-Mao Li, Yao-chen Huang, Qi-Dong Xia, Peng Zhou, Xian-Miao Li, Xiao Yu, Shao-Gang Wang, Zhang-Qun Ye and Jia Hu
    Citation: Cancer Cell International 2021 21:641
  13. Osteosarcoma (OS) metastasis is the most common cause of cancer-related mortality, however, no sufficient clinical biomarkers have been identified. In this study, we identified five genes to help predict metas...

    Authors: Fu-peng Ding, Jia-yi Tian, Jing Wu, Dong-feng Han and Ding Zhao
    Citation: Cancer Cell International 2021 21:640
  14. Cervical cancer (CC) is the leading cause of cancer-related death in women. A limited number of studies have investigated whether immune-prognostic features can be used to predict the prognosis of CC. This stu...

    Authors: Ya-Nan Pi, Jun-Nan Guo, Ge Lou and Bin-Bin Cui
    Citation: Cancer Cell International 2021 21:639
  15. The emergence of chemoresistance to 5-fluorouracil (5-FU)-based chemotherapy is the main cause of treatment failure in advanced and metastatic colorectal cancer (CRC) patients. Long noncoding RNAs (lncRNAs) ha...

    Authors: Jingui Wang, Xiaoqian Zhang, Junling Zhang, Shangwen Chen, Jing Zhu and Xin Wang
    Citation: Cancer Cell International 2021 21:638
  16. Esophageal carcinogenesis is a multifactorial process in which genetic and environmental factors interact to activate intracellular signals, leading to the uncontrolled survival and growth of esophageal squamo...

    Authors: Jia Zhao, Guangyu Jin, Xudong Liu, Kai Wu, Yang Yang, Zhanfeng He, Donglei Liu, Chunyang Zhang, Dengyan Zhu, Jia Jiao, Xiangnan Li and Song Zhao
    Citation: Cancer Cell International 2021 21:637
  17. Circular RNAs (circRNAs), which are endogenous non-coding RNAs, are associated with various biological processes including development, homeostatic maintenance, and pathological responses. Accumulating evidenc...

    Authors: Yu Huang, Wenhao Ge, Yuan Ding, Lufei Zhang, Jiarong Zhou, Yang Kong, Bijun Cui, Bingqiang Gao, Xiaohui Qian and Weilin Wang
    Citation: Cancer Cell International 2021 21:636
  18. The tumor microenvironment (TME) is critical in the progression and metastasis of skin cutaneous melanoma (SKCM). Differences in tumor-infiltrating immune cells (TICs) and their gene expression have been linke...

    Authors: Peipei Yang, Wanrong Chen, Hua Xu, Junhan Yang, Jinghang Jiang, Yunhui Jiang and Ganglin Xu
    Citation: Cancer Cell International 2021 21:635
  19. Rhabdomyosarcoma (RMS) is a malignant soft-tissue tumour. In recent years, the tumour microenvironment (TME) has been reported to be associated with the development of tumours. However, the relationship betwee...

    Authors: Tian Xia, Lian Meng, Zhijuan Zhao, Yujun Li, Hao Wen, Hao Sun, Tiantian Zhang, Jingxian Wei, Feng Li and Chunxia Liu
    Citation: Cancer Cell International 2021 21:634
  20. Current treatment options for glioma are limited, and the prognosis of patients with glioma is poor as the available drugs show low therapeutic efficacy. Furthermore, the molecular mechanisms associated with g...

    Authors: Lun Li, Yi Yang, Zhenshuang Wang, Chengran Xu, Jinhai Huang and Guangyu Li
    Citation: Cancer Cell International 2021 21:633
  21. The precancerous disease of breast cancer is an inevitable stage in the tumorigenesis and development of breast neoplasms. Quercetin (Que) has shown great potential in breast cancer treatment by inhibiting cel...

    Authors: Dan Qiu, Xianxin Yan, Xinqin Xiao, Guijuan Zhang, Yanqiu Wang, Jingyu Cao, Ruirui Ma, Shouyi Hong and Min Ma
    Citation: Cancer Cell International 2021 21:632
  22. A number of studies have indicated that Ubiquitin-conjugating enzyme E2T (UBE2T), as an oncogene, promotes progression and metastasis of lung cancer, including lung adenocarcinoma (LUAD), but it is completely ...

    Authors: Yongbing Chen, Haihua Hong, Qingqing Wang, Junqiang Li, Wenfeng Zhang, Tingting Chen and Pu Li
    Citation: Cancer Cell International 2021 21:631
  23. Osteosarcoma is a primary malignant tumor that mainly affects children and young adults. Transmembrane emp24 trafficking protein 3 (TMED3) may be involved in the regulation of malignant cancer behaviors. Howev...

    Authors: Wei Xu, Yifan Li, Xiaojian Ye, Yunhan Ji, Yu Chen, Xiangyang Zhang and Zhikun Li
    Citation: Cancer Cell International 2021 21:630
  24. MicroRNA (miRNA) that translocate from the nucleus to mitochondria are referred to as mitochondrial microRNA (mitomiR). Albeit mitomiRs have been shown to modulate gene expression, their functional impact with...

    Authors: Praveen Sharma, Vibhuti Sharma, Tarunveer Singh Ahluwalia, Nilambra Dogra, Santosh Kumar and Sandeep Singh
    Citation: Cancer Cell International 2021 21:629
  25. Non-small cell lung cancer (NSCLC) accounts for more than 80% of lung cancers, which is the most common malignant tumor worldwide. Polypeptide extract from scorpion venom (PESV) has been reported to inhibit NS...

    Authors: Hong Zhang, Haojian Zhang, Jiye Zhu, Huan Liu and Qin Zhou
    Citation: Cancer Cell International 2021 21:628
  26. Cancer cachexia is a wasting disorder characterized by significant weight loss, and is attributed to skeletal muscle weakness. In the process of cancer development, microRNAs act as oncogenes or tumor suppress...

    Authors: Kairu Xie, Hairong Xiong, Wen Xiao, Zhiyong Xiong, Wenjun Hu, Jiaxin Ye, Ning Xu, Jian Shi, Changfei Yuan, Zhixian Chen, Daojia Miao, Xiaoping Zhang and Hongmei Yang
    Citation: Cancer Cell International 2021 21:627
  27. Controversial findings have been reported in the impact of speckle-type POZ protein (SPOP) on clinicopathological features and prognosis in diverse cancers. We conducted this meta-analysis to confirm whether S...

    Authors: Yan He, Jun Chen, Xingchen Peng, Yanli Xia and Yonglin Su
    Citation: Cancer Cell International 2021 21:626
  28. This article aimed to explore the prognostic and immunological roles of AXL gene in clear cell renal cell carcinoma (ccRCC) for overall survival (OS) and to identify the LncRNA/RBP/AXL mRNA networks.

    Authors: Yi Wang, Ye Tian, Shouyong Liu, Zengjun Wang and Qianwei Xing
    Citation: Cancer Cell International 2021 21:625
  29. Long non-coding RNAs (lncRNAs) have been verified to play fatal role in regulating the progression of lung adenocarcinoma (LUAD). Although lncRNAs play important role in regulating the autophagy of tumor cells...

    Authors: Zhuochen Zhao, Junhu Wan, Manman Guo, Zhengwu Yang, Zhuofang Li, Yangxia Wang and Liang Ming
    Citation: Cancer Cell International 2021 21:624
  30. Acquired glucocorticoid (GC) resistance remains the main obstacle in acute lymphoblastic leukemia (ALL) therapy. The aim of the present study was to establish a novel GC-resistant B-ALL cell line and investiga...

    Authors: Yuanyuan Li, Chuan Zuo and Ling Gu
    Citation: Cancer Cell International 2021 21:623
  31. Morphine, a µ-opioid receptor (MOR) agonist, has been shown to be related to the activity of cancer cells, and a higher morphine dosage reduces the survival time of patients with lung cancer. However, the effe...

    Authors: Xingyun Liu, Jia Yang, Chengwei Yang, Xiang Huang, Mingming Han, Fang Kang and Juan Li
    Citation: Cancer Cell International 2021 21:622
  32. The aim of this study was to construct a model based on the prognostic features associated with epithelial–mesenchymal transition (EMT) to explore the various mechanisms and therapeutic strategies available fo...

    Authors: Dafeng Xu, Yu Wang, Jincai Wu, Shixun Lin, Yonghai Chen and Jinfang Zheng
    Citation: Cancer Cell International 2021 21:621
  33. Pancreatic cancer has been a threateningly lethal malignant tumor worldwide. Despite the promising survival improvement in other cancer types attributing to the fast development of molecular precise medicine, ...

    Authors: Rong Wei, Guoye Qi, Zixin Zeng, Ningning Shen, Ziyue Wang, Honghong Shen, Lifang Gao, Chen Song, Wenxia Ma and Chen Wang
    Citation: Cancer Cell International 2021 21:620
  34. Neuroblastoma (NB) is a common solid malignancy in children that is associated with a poor prognosis. Although the novel small molecular compound Dimethylaminomicheliolide (DMAMCL) has been shown to induce cel...

    Authors: Simeng Zhang, Zhongyan Hua, Gen Ba, Ning Xu, Jianing Miao, Guifeng Zhao, Wei Gong, Zhihui Liu, Carol J. Thiele and Zhijie Li
    Citation: Cancer Cell International 2021 21:619
  35. Papillary thyroid carcinoma (PTC) is a common endocrine tumor. Increasing evidence has shown that microRNA dysfunction is involved in the occurrence and development of cancer. The expression of MicroRNA-30b-5p...

    Authors: Ye Wang, Congjun Wang, Zhao Fu, Siwen Zhang and Junqiang Chen
    Citation: Cancer Cell International 2021 21:618
  36. UCA1 is frequently upregulated in a variety of cancers, including CRC, and it can play an oncogenic role by various mechanisms. However, how UCA1 is regulated in cancer is largely unknown. In this study, we ai...

    Authors: Rong-Zhang He, Jing Jiang, Xinglin Hu, Ming Lei, Jia Li, Weihao Luo, Lili Duan, Zheng Hu, Yin-Yuan Mo, Di-Xian Luo and Wan-Xin Peng
    Citation: Cancer Cell International 2021 21:616
  37. There is mounting evidence that demonstrated the association of aberrant NEDD4L expression with diverse human cancers. However, the expression pattern and clinical implication of NEDD4L in acute myeloid leukemia ...

    Authors: Ming-qiang Chu, Liu-chao Zhang, Qian Yuan, Ting-juan Zhang and Jing-dong Zhou
    Citation: Cancer Cell International 2021 21:615
  38. Most previous studies compared the risk for non-melanoma skin cancer (NMSC) in biologic-treated common inflammatory diseases with the general population. Whether the increased NMSC risk is caused by the diseas...

    Authors: Ruolin Liu, Qianyi Wan, Rui Zhao, Haitao Xiao, Ying Cen and Xuewen Xu
    Citation: Cancer Cell International 2021 21:614
  39. Bladder cancer (BLCA) is the most common genitourinary tumor but lacks specific diagnostic biomarkers. Recent years have witnessed significant advances in the use and approval of immune checkpoint blockade (IC...

    Authors: YiHeng Du, Jin Cao, Xiang Jiang, XiaoWei Cai, Bo Wang, Yi Wang, XiZhi Wang and BoXin Xue
    Citation: Cancer Cell International 2021 21:613
  40. Cancer is the second most killer worldwide causing millions of people to lose their lives every year. In the case of women, breast cancer takes away the highest proportion of mortality rate than other cancers....

    Authors: Shabnam Sharmin, Md. Mizanur Rahaman, Miquel Martorell, Jorge Sastre-Serra, Javad Sharifi-Rad, Monica Butnariu, Iulia Cristina Bagiu, Radu Vasile Bagiu and Mohammad Torequl Islam
    Citation: Cancer Cell International 2021 21:612
  41. The underlying circular RNAs (circRNAs)-related competitive endogenous RNA (ceRNA) mechanisms of pathogenesis and prognosis in non-small cell lung cancer (NSCLC) remain unclear.

    Authors: Jia Yang, Ran Hao, Yunlong Zhang, Haibin Deng, Wenjing Teng and Zhongqi Wang
    Citation: Cancer Cell International 2021 21:611
  42. The accumulation of single nucleotide variants (SNVs) and the emergence of neoantigens can affect tumour proliferation and the immune microenvironment. However, the SNV-related immune microenvironment characte...

    Authors: Yu-Jie Xu, Min-Ke He, Shuang Liu, Li-Chang Huang, Xiao-Yun Bu, Anna Kan and Ming Shi
    Citation: Cancer Cell International 2021 21:610
  43. N6-methyladenosine (m6A) is the most abundant RNA modification of mammalian mRNAs and plays a vital role in many diseases, especially tumours. In recent years, m6A has become the topic of intense discussion in...

    Authors: Jialu Guo, Jianfeng Zheng, Huizhi Zhang and Jinyi Tong
    Citation: Cancer Cell International 2021 21:609
  44. Gallbladder cancer (GBC) is the most common biliary tract malignancy and has a poor prognosis in patients with GBC. CircRNA TP63 (circTP63) has been implicated in cell proliferation and invasion in some tumor ...

    Authors: Shouhua Wang, Huanjun Tong, Tingting Su, Di Zhou, Weibin Shi, Zhaohui Tang and Zhiwei Quan
    Citation: Cancer Cell International 2021 21:608
  45. Uveal melanoma (UM), the most prevalent intraocular tumor in adults, is a highly metastatic and drug resistant lesion. Recent studies have demonstrated cytotoxic and anti-metastatic effects of the antiprogesti...

    Authors: Prisca Bustamante Alvarez, Alexander Laskaris, Alicia A. Goyeneche, Yunxi Chen, Carlos M. Telleria and Julia V. Burnier
    Citation: Cancer Cell International 2021 21:607
  46. Sestrin 2, a highly conserved stress-induced protein, participates in the pathological processes of metabolic and age-related diseases. This p53-inducible protein also regulates cell growth and metabolism, whi...

    Authors: Junsheng Qu, Moyi Luo, Jingwen Zhang, Fang Han, Ningning Hou, Ruiyan Pan and Xiaodong Sun
    Citation: Cancer Cell International 2021 21:606
  47. Breast cancer is a common cancer among women in the world. However, its pathogenesis is still to be determined. The role and molecular mechanism of Nucleosome Assembly Protein 1 Like 1 (NAP1L1) in breast cance...

    Authors: Shu Liu, Yewei Zhang, Shien Cui, Dajiang Song, Bo Li, Qian Chen, Guangyu Yao and Bin Gong
    Citation: Cancer Cell International 2021 21:605

    The Correction to this article has been published in Cancer Cell International 2022 22:26

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